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Translating Immunology

This collection showcases bench-to-bedside review articles that highlight immunological discoveries that have led to a treatment, drug, or diagnostic device.

TRANSLATING IMMUNOLOGY

Therapeutic Opportunities for Immunoreceptor-Engineered T Cell Therapy for Modulation of Alloimmunity

Kavitha Muralidharan; Divyansh Agarwal; Ali Naji; Vijay G. Bhoj

https://doi.org/10.4049/jimmunol.2200542

TRANSLATING IMMUNOLOGY

Translating JAKs to Jakinibs

Massimo Gadina; Danielle A. Chisolm; Rachael L. Philips; Iain B. McInness; Paul S. Changelian; John J. O’Shea

https://doi.org/10.4049/jimmunol.1901477

TRANSLATING IMMUNOLOGY

A 20-Year Journey from Axonal Injury to Neurodegenerative Diseases and the Prospect of Immunotherapy for Combating Alzheimer’s Disease

Michal Schwartz; Javier M. Peralta Ramos; Hila Ben-Yehuda

https://doi.org/10.4049/jimmunol.1900844

TRANSLATING IMMUNOLOGY

Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases

Maryam Tahvildari; Reza Dana

https://doi.org/10.4049/jimmunol.1900733

TRANSLATING IMMUNOLOGY

T Cell–Activating Bispecific Antibodies in Cancer Therapy

Asaad Trabolsi; Artavazd Arumov; Jonathan H. Schatz

https://doi.org/10.4049/jimmunol.1900496

TRANSLATING IMMUNOLOGY

Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis

Jason E. Hawkes; Bernice Y. Yan; Tom C. Chan; James G. Krueger

https://doi.org/10.4049/jimmunol.1800013

TRANSLATING IMMUNOLOGY

Passive Serum Therapy to Immunomodulation by IVIG: A Fascinating Journey of Antibodies

Cristina João; Vir Singh Negi; Michel D. Kazatchkine; Jagadeesh Bayry; Srini V. Kaveri

https://doi.org/10.4049/jimmunol.1701271

TRANSLATING IMMUNOLOGY

Inhibitors of the PD-1 Pathway in Tumor Therapy

Martin W. LaFleur; Yuki Muroyama; Charles G. Drake; Arlene H. Sharpe

https://doi.org/10.4049/jimmunol.1701044

TRANSLATING IMMUNOLOGY

Natalizumab for Multiple Sclerosis: A Case in Point for the Impact of Translational Neuroimmunology

Afsaneh Shirani; Olaf Stüve

https://doi.org/10.4049/jimmunol.1601358

TRANSLATING IMMUNOLOGY

From IgE to Omalizumab

Toshiaki Kawakami; Ulrich Blank

https://doi.org/10.4049/jimmunol.1601476

TRANSLATING IMMUNOLOGY

Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway

Andrew B. Adams; Mandy L. Ford; Christian P. Larsen

https://doi.org/10.4049/jimmunol.1601135

TRANSLATING IMMUNOLOGY

The Opportunity To Eradicate Peste des Petits Ruminants

Jeffrey C. Mariner; Bryony A. Jones; Karl M. Rich; Samuel Thevasagayam; John Anderson; Martyn Jeggo; Yi Cai; Andrew R. Peters; Peter L. Roeder

https://doi.org/10.4049/jimmunol.1502625

TRANSLATING IMMUNOLOGY

G-CSF and GM-CSF in Neutropenia

Hrishikesh M. Mehta; Michael Malandra; Seth J. Corey

https://doi.org/10.4049/jimmunol.1500861

TRANSLATING IMMUNOLOGY

Chimeric Antigen Receptor– and TCR-Modified T Cells Enter Main Street and Wall Street

David M. Barrett; Stephan A. Grupp; Carl H. June

https://doi.org/10.4049/jimmunol.1500751

TRANSLATING IMMUNOLOGY

Translational Medicine in Action: Anti-CD20 Therapy in Lymphoma

Sean H. Lim; Ronald Levy

https://doi.org/10.4049/jimmunol.1490027

TRANSLATING IMMUNOLOGY

IL-2: The First Effective Immunotherapy for Human Cancer

Steven A. Rosenberg

https://doi.org/10.4049/jimmunol.1490019

TRANSLATING IMMUNOLOGY

Development and Implementation of Papillomavirus Prophylactic Vaccines

Ian H. Frazer

https://doi.org/10.4049/jimmunol.1490012

TRANSLATING IMMUNOLOGY

Calcineurin Inhibitors: 40 Years Later, Can’t Live Without …

Jamil R. Azzi; Mohamed H. Sayegh; Samir G. Mallat

https://doi.org/10.4049/jimmunol.1390055

TRANSLATING IMMUNOLOGY

IFN-α in the Treatment of Melanoma

Ahmad A. Tarhini; Helen Gogas; John M. Kirkwood

https://doi.org/10.4049/jimmunol.1290060

TRANSLATING IMMUNOLOGY

Translational Applications of Flow Cytometry in Clinical Practice

David L. Jaye; Robert A. Bray; Howard M. Gebel; Wayne A. C. Harris; Edmund K. Waller

https://doi.org/10.4049/jimmunol.1290017

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Translating Immunology

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Translating Immunology

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