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Volume 8, Issue 9
1 September 2024
ImmunoHorizons Cover Image for Volume 8, Issue 9
EISSN 2573-7732

ADAPTIVE IMMUNITY

α-Hemolysin from Staphylococcus aureus Changes the Epigenetic Landscape of Th17 Cells
Joanna Pastwińska; Iwona Karwaciak; Kaja Karaś; Anna Sałkowska; Katarzyna Chałaśkiewicz; Dominik Strapagiel; Marta Sobalska-Kwapis; Jarosław Dastych; Marcin Ratajewski
Immunohorizons (2024) 8 (9): 606–621.
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Estimates of Sequences with Ultralong and Short CDR3s in the Bovine IgM B Cell Receptor Repertoire Using the Long-read Oxford Nanopore MinION Platform
Tess E. Altvater-Hughes; Harold P. Hodgins; Douglas C. Hodgins; Natasha B. Gallo; Gabhan I. Chalmers; Nicole D. Ricker; Bonnie A. Mallard
Immunohorizons (2024) 8 (9): 635–651.
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B Cells Influence Encephalitogenic T Cell Frequency to Myelin Oligodendrocyte Glycoprotein (MOG)38–49 during Full-length MOG Protein–Induced Demyelinating Disease
Michael A. Faust; Lisa Gibbs; Juan M. Oviedo; Douglas H. Cornwall; Keke C. Fairfax; Zemin Zhou; Tracey J. Lamb; Brian D. Evavold
Immunohorizons (2024) 8 (9): 729–739.
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CLINICAL AND TRANSLATIONAL IMMUNOLOGY

Improving Reliability of Immunological Assays by Defining Minimal Criteria for Cell Fitness
Sabine Ivison; Gabrielle Boucher; Grace Zheng; Rosa V. Garcia; Rita Kohen; Alain Bitton; John D. Rioux; Megan K. Levings; iGenoMed Consortium
Immunohorizons (2024) 8 (9): 622–634.
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Probing Dermal Immunity to Mycobacteria through a Controlled Human Infection Model
E. Chandler Church; Emma Bishop; Andrew Fiore-Gartland; Krystle K. Q. Yu; Ming Chang; Richard M. Jones; Justin K. Brache; Lamar Ballweber Fleming; Jolie M. Phan; Mohau S. Makatsa; Jack Heptinstall; Kelvin Chiong; One Dintwe; Anneta Naidoo; Valentin Voillet; Koshlan Mayer-Blackwell; Gift Nwanne; Erica Andersen-Nissen; Jay C. Vary, Jr.; Georgia D. Tomaras; M. Juliana McElrath; David R. Sherman; Sean C. Murphy; James G. Kublin; Chetan Seshadri
Immunohorizons (2024) 8 (9): 695–711.
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INNATE IMMUNITY

Bruton Tyrosine Kinase Inhibition Decreases Inflammation and Differentially Impacts Phagocytosis and Cellular Metabolism in Mouse- and Human-derived Myeloid Cells
Rochelle Y. Benoit; Jennifer L. Zagrodnik; Samantha J. Carew; Craig S. Moore
Immunohorizons (2024) 8 (9): 652–667.
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HDAC6 Deletion Decreases Pristane-induced Inflammation
Dao Xu; Xin M. Luo; Christopher M. Reilly
Immunohorizons (2024) 8 (9): 668–678.
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Gasdermin D and Gasdermin E Are Dispensable for Silica-Mediated IL-1β Secretion from Mouse Macrophages
Jennifer Leung; Michael Chang; Richard E. Moore; Jargalsaikhan Dagvadorj; Fayyaz S. Sutterwala; Suzanne L. Cassel
Immunohorizons (2024) 8 (9): 679–687.
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Pseudomonas aeruginosa Mediates Host Necroptosis through Rhl-Pqs Quorum Sensing Interaction
Zihao Liu; Lu Sun; Lupeng Li; Edward A. Miao; Amal O. Amer; Daniel J. Wozniak; Haitao Wen
Immunohorizons (2024) 8 (9): 721–728.
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INFECTIOUS DISEASE

Chemokine Receptor CCR2 Is Protective toward Outer Hair Cells in Chronic Suppurative Otitis Media
Ankur Gupta; Viktoria Schiel; Ritwija Bhattacharya; Kourosh Eftekharian; Anping Xia; Peter L. Santa Maria
Immunohorizons (2024) 8 (9): 688–694.
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Human ACE2 Gene Replacement Mice Support SARS-CoV-2 Viral Replication and Nonlethal Disease Progression
Joshua M. Thiede; Jenna K. Dick; Nicholas N. Jarjour; Venkatramana D. Krishna; Lily Qian; Jules Sangala; Kellie Benzow; Kul Karanjeet; Shine Chin; Orion Rainwater; Maxim C.-J. Cheeran; Kristin A. Hogquist; Stephen C. Jameson; Geoffrey T. Hart; Tyler D. Bold; Michael D. Koob
Immunohorizons (2024) 8 (9): 712–720.
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  • Cover Image

    Cover Image

    issue cover

    On the cover: ACE2 gene replacement (ACE2-GR) mice were generated, in which the locus containing Ace2 was substituted with the syntenic region of the human genome, providing a model for SARS-CoV-2 infection. Homozygous ACE2-GR mice were analyzed for ACE2 expression (brown staining) in tissue sections of lung. Thiede, J. M., J. K. Dick, N. N. Jarjour, V. D. Krishna, L. Qian, J. Sangala, K. Benzow, K. Karanjeet, S. Chin, O. Rainwater, M. C.-J. Cheeran, K. A. Hogquist, S. C. Jameson, G. T. Hart, T. D. Bold, and M. D. Koob. 2024. Human ACE2 gene replacement mice support SARS-CoV-2 viral replication and nonlethal disease progression. Immunohorizons. 8: 712–720.

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  • Online ISSN 2573-7732

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