1. Agglutinability of Blood and Agar Strains of Typhoid Bacilli. Carroll G. Bull, and Ida W. Pritchett: Gay and Claypole found that two generations on 10 per cent rabbit blood agar rendered typhoid bacilli inagglutinable to an immune serum produced by a plain agar strain, but that a serum produced by a blood strain agglutinated equally well both blood agar and plain agar strains.1 These authors observed also that a blood strain immune serum agglutinated freshly isolated inagglutinable strains, and they were thus able to identify such strains without first growing them for a number of generations on artificial media.

In contemplating the production of a general agglutinating serum according to the above method, we first attempted to render our laboratory strains inagglutinable by growing them on 10 per cent rabbit blood agar. Two generations on blood agar failed to change the agglutinability of these strains. Cultivation on blood agar was continued and the agglutinability tested with an agar strain immune serum after each two or three successive transfers.

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