Abstract
During the past several years this talk has been an occasion for historical, philosophical, or pedagogic presentations. I want to return to the earlier tradition and address my remarks to a scientific subject that is currently of great interest to me, namely, the similarities between humoral and cellular immunity.
For a century, immunology has been divided into two worlds, one humoral, the other cellular. I believe there are clear indications that this era is now drawing to a close as a consequence of studies of the various mediators that are operative in the trans-antibody domain of humoral and cellular immunity. It is my impression that we are witnessing one of those exciting developments in scientific research in which a series of diverse facts gives rise to hypothetical concepts that are eventually developed into the satisfying pattern of a theory.
