This Pillars of Immunology article is a commentary on “The Inflammasome: A Molecular Platform Triggering Activation of Inflammatory Caspases and Processing of proIL-β,” a pivotal article written by F. Martinon, K. Burns, and J. Tschopp, published in Molecular Cell in 2002. https://doi.org/10.1016/S1097-2765(02)00599-3.

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