The studies described lead to the conclusion that the M-protein is definitely antigenic even though subjected to drastic methods of isolation and purification. The isolated M-protein is not nearly as antigenic, however, as intact streptococci which are believed to contain a fiftieth or less of their weight as M-protein.

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Copyright © 1942 by The American Association of Immunologists, Inc.
1942
Williams & Wilkins Company
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