Studies of the rate of antigen absorption in sensitized and immunized animals, as contrasted with the rate of absorption in normal animals, have shown that previous treatment with an antigen confers upon an animal an increased power of absorption for that antigen. This fact was established with respect to sensitized rabbits and guinea-pigs by Doerr and Pick (1), Friedberger and Lurà (2), Römer and Viereck (3), and others. Smith and Cook (4) confirmed the work of Doerr and Pick and further (5) demonstrated that absorption of antigen in immunized animals proceeds much more rapidly than in sensitized or normal animals.

As it is evident that upon sensitization and particularly upon immunization, an animal acquires increased powers of absorption for the specific antigen, the question arises as to whether the process of immunity production is in any way dependent upon the changed absorptive powers of the organism.

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