Abstract
Whole goldfish anti-bovine serum albumin (BSA) serum was fractionated to yield two populations of antibody-containing immunoglobulins of different charge. Whole serum protein homologies of the two antibody preparations were demonstrated by Osserman-type immunoelectrophoretic tests. Diffusion-in-gel tests indicated that the two antibody populations shared at least one antigenic determinant, although one population was antigenically deficient with respect to the other. On the basis of their whole-serum homologies and antigenic disparities, the two antibody populations are thought to represent distinct serum proteins.
Footnotes
This work was supported by United States National Institutes of Health Grant AI-07970.
Parts of this work were reported at the annual meeting of the Federation of American Societies for Experimental Biology, 1968.
