Anti-Vκ region antisera and anti-Cκ,λ region antiserum were used to investigate the nature of antigen recognition units of T cells. The results did not support the hypothesis that T cells contain relatively large amounts of V regions with undetectable amounts of C regions which are buried in the membrane but indicated that with specific anti-κI and anti-κIII antisera the detectable V region determinants were confined to the B cell population.

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This work was supported in part by United States Public Health Service Grants AI-09758, and CA-10056, and American Heart Association Grant 70-749.

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Copyright © 1973 by The American Association of Immunologists, Inc.
1973
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