The concentration of macrophages per gram tumor was as much as five times greater in regressing compared to progressing Moloney sarcomas. Infiltrating mononuclear cells, including macrophages, were closely associated with a cessation of mitotic activity in tumors.

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This work was supported by United States Public Health Service Contract N01-CB-44001, Grant AI 07007, California Division—American Cancer Society Junior Fellowship J-235, and the Lilly International Fellowship Foundation. This is manuscript No. 1016 from the Department of Immunopathology, Scripps Clinic and Research Foundation, 476 Prospect Street, La Jolla, California 92037.

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Copyright © 1976 by The American Association of Immunologists, Inc.
1976
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