Dual Binding Specificities in Mopc 384 and 870 Murine Myeloma Immunoglobulins

Homogeneous murine myeloma immunoglobulins (IgA, κ), M 384, and M 870, bind methyl α-D-galactopyranoside and phosphorylcholine at different subsites. Heterologous recombinant immunoglobulins of these two immunoglobulins with M 603 (a homogeneous IgA, κ with known phosphorylcholine specificity) also bind phosphorylcholine.