Conjugate formation between effector T cells raised in vivo in a BALB/c host and fluorescein diacetate-labeled allogeneic EL4 tumor target cells was observed and scored by using a fluorescence microscope. This conjugate formation was found to be specifically inhibited by plasma membrane vesicles isolated from the EL4 cells.

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This work was supported by the National Institutes of Health Training Grant GM07026, Grants AI07757, AI13587-01 and AI13587-02.

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