Conjugate formation between effector T cells raised in vivo in a BALB/c host and fluorescein diacetate-labeled allogeneic EL4 tumor target cells was observed and scored by using a fluorescence microscope. This conjugate formation was found to be specifically inhibited by plasma membrane vesicles isolated from the EL4 cells.


This work was supported by the National Institutes of Health Training Grant GM07026, Grants AI07757, AI13587-01 and AI13587-02.

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