Lymph node cells from guinea pigs with specific delayed hypersensitivity release macrophage agglutination (MAggF) and migration inhibition factors (MIF) upon exposure to antigen or concanavalin A in serumfree medium. MAggF in culture supernatants was absorbed neither by immunoabsorbents made with a rabbit anti-guinea pig lymphokine serum that removed MIF, nor by immunoabsorbents made with rabbit anti-guinea pig Ig. These results suggest that MAggF is antigenically distinct from MIF and Ig.


This work was supported by grants from the Swiss National Foundation for Scientific Research, Kroc Foundation and U. S. National Institutes of Health (General Research Support Grant 5 S07RR0573605).

This content is only available via PDF.