Takeda, K., T. Kaisho, N. Yoshida, J. Takeda, T. Kishimoto, and S. Akira. 1998. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J. Immunol. 161: 4652–4660.
In Fig. 6 as originally published, the FACS dot plot in the lower row of the IL-6 column was mistakenly duplicated from the lower row of the medium column, and the percentages in the left lower column were mislabeled. The corrected figure is shown below. The results and conclusions of the article remain unchanged. The figure legend was correct as published and is shown below for reference.
IL-6-induced prevention of T cell apoptosis was impaired in Lck-Cre/Stat3flox/− mice. Splenic T cells from wild-type and Lck-Cre/Stat3flox/− mice were cultured in 0.1% FCS culture medium in the presence of 10 ng/ml IL-6 and/or 100 ng/ml anti-CD3 Ab for 5 h. Then cells were stained with FITC-annexin V and PI.
IL-6-induced prevention of T cell apoptosis was impaired in Lck-Cre/Stat3flox/− mice. Splenic T cells from wild-type and Lck-Cre/Stat3flox/− mice were cultured in 0.1% FCS culture medium in the presence of 10 ng/ml IL-6 and/or 100 ng/ml anti-CD3 Ab for 5 h. Then cells were stained with FITC-annexin V and PI.
