We wish to retract the article titled “Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor” by Melanie L. Hart, Almut Grenz, Iris C. Gorzolla, Jens Schittenhelm, Julee H. Dalton, and Holger K. Eltzschig, The Journal of Immunology, 2011, 186: 4367–4374.
We recently became aware of some potentially inappropriate duplication of histologic images and Western blots in our research paper (in Fig. 1B, actin bands are possibly duplicated as CD73 bands; in Fig. 2E, the left column lower and upper images are possibly duplicated and the lower right image appears to be the same as the lower right image of Fig. 5E; and some lanes in the Western blots in Figs. 3B and 6A are potentially spliced without appropriate indication). We were not able to provide the original data for these figures, and thus they cannot be validated. Based on these concerns, all authors, with the exception of Dr. Almut Grenz, have agreed that we would like to retract this research paper. We deeply apologize to our colleagues and the scientific community for any inconvenience this may have caused.
Melanie L. Hart
Albert-Ludwigs-University of Freiburg Freiburg, Germany
Iris C. Gorzolla
Marienhospital Stuttgart Stuttgart, Germany
Tübingen University Hospital Tübingen, Germany
Julee H. Dalton
UCSF Benioff Children's Hospital Oakland Oakland, CA
Holger K. Eltzschig
McGovern Medical School The University of Texas Health Science Center at Houston Houston, TX