The literature of the last ten years contains a great many reports of the successful treatment of various acute infectious diseases with suspensions of the dead bacteria causing the disease, i.e., homologous “vaccines.” However, although this method has attained universal acceptance as a prophylactic measure in typhoid fever, cholera and paratyphoid infections, and promises similar prospects in some other conditions, it can hardly be said that it has been more than hopefully suggestive as a therapeutic procedure used during the course of actual disease. Indeed there has been an increasing suspicion among bacteriologists that the effects produced, when bacterial protein was injected into patients, were not in any sense specific, and depended rather upon the general character of the injected substances as bacterial proteins, than upon their specifically immunizing properties.

This content is only available via PDF.