1. The rhesus monkey was shown to be rendered relatively susceptible to infection with fresh tissue derived from human trachoma, by previous preparation of the conjunctiva by irritation with powdered Portland cement. Clinically and histologically, these lesions resemble those induced in other varieties of monkeys and can be transmitted in series from rhesus to rhesus.

  2. The New World monkey, Cebus capucinus, was also found to be susceptible to infection with human material.

  3. No evidence of a filterable virus was found in tissues removed from monkeys whose conjunctivae had developed lesions in reponse to inoculation with human trachomatous material.

  4. No evidence of an inclusion producing virus was found, upon serial passage of human trachomatous material from brain to brain or from testis to brain of mice or rabbits.

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Conducted under grant from the Commonwealth Fund. Present address: Mount Zion Hospital and Hooper Foundation, University of California, San Francisco.

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