All rabbits possessing normal group-specific β agglutinins produced immune group-specific β agglutinins. About two-thirds of the animals lacking normal agglutinins produced specific β agglutinins upon immunization.

The B1 antigen could not be demonstrated in the tissues, blood cells, or serum of rabbits incapable of producing group-specific β agglutinins.

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This work was supported in part by a grant from the Rockefeller Foundation.

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