1. Hyperimmune rabbit sera against eastern and western equine encephalomyelitis, St. Louis and Japanese B encephalitis and rabies have been fractionated by electrophoresis.

  2. Neutralization tests performed on all fractions revealed the antibodies to be present almost exclusively in the gamma globulin.

  3. Normal sera and electrophoretically separated fractions thereof appeared to exert some nonspecific masking effect on the virus.

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