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Volume 150, Issue 12
15 June 1993
Issue Cover
ISSN 0022-1767
EISSN 1550-6606
In this Issue

ARTICLES

Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins.
W H Alwan; F M Record; P J Openshaw
J Immunol (1993) 150 (12): 5211–5218.
View articletitled, Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins.
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Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative.
R A Daynes; B A Araneo; W B Ershler; C Maloney; G Z Li; S Y Ryu
J Immunol (1993) 150 (12): 5219–5230.
View articletitled, Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative.
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Dissection of the function of HLA class II and costimulation in B cell-mediated and toxic shock syndrome toxin-1-induced T cell proliferation.
D Dennig; R J O'Reilly
J Immunol (1993) 150 (12): 5231–5240.
View articletitled, Dissection of the function of HLA class II and costimulation in B cell-mediated and toxic shock syndrome toxin-1-induced T cell proliferation.
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Identification of functional domains in murine granulocyte-macrophage colony-stimulating factor using monoclonal antibodies to synthetic peptides.
R S Greenfield; G R Braslawsky; K F Kadow; G L Spitalny; D Chace; C O Bull; I Bursuker
J Immunol (1993) 150 (12): 5241–5251.
View articletitled, Identification of functional domains in murine granulocyte-macrophage colony-stimulating factor using monoclonal antibodies to synthetic peptides.
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Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells.
G Laszlo; K S Hathcock; H B Dickler; R J Hodes
J Immunol (1993) 150 (12): 5252–5262.
View articletitled, Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells.
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Genesis of human oncolytic natural killer cells from primitive CD34+CD33- bone marrow progenitors.
E Lotzová; C A Savary; R E Champlin
J Immunol (1993) 150 (12): 5263–5269.
View articletitled, Genesis of human oncolytic natural killer cells from primitive CD34+CD33- bone marrow progenitors.
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Role of thiols in the presentation of a snake toxin to murine T cells.
B Maillère; J Cotton; G Mourier; M Léonetti; S Leroy; A Ménez
J Immunol (1993) 150 (12): 5270–5280.
View articletitled, Role of thiols in the presentation of a snake toxin to murine T cells.
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Modulation of T lymphocyte function by neuropeptides. Evidence for their role as local immunoregulatory elements.
D A Nio; R N Moylan; J K Roche
J Immunol (1993) 150 (12): 5281–5288.
View articletitled, Modulation of T lymphocyte function by neuropeptides. Evidence for their role as local immunoregulatory elements.
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MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors.
N Odum; S B Kanner; J A Ledbetter; A Svejgaard
J Immunol (1993) 150 (12): 5289–5298.
View articletitled, MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors.
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Isotypic residues in the membrane proximal domain of MHC class II beta-chains control activation of CD4+ T cells.
A J Sant
J Immunol (1993) 150 (12): 5299–5310.
View articletitled, Isotypic residues in the membrane proximal domain of MHC class II beta-chains control activation of CD4+ T cells.
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Characterization of the EBV/C3d receptor on the human Jurkat T cell line: evidence for a novel transcript.
S K Sinha; S C Todd; J A Hedrick; C L Speiser; J D Lambris; C D Tsoukas
J Immunol (1993) 150 (12): 5311–5320.
View articletitled, Characterization of the EBV/C3d receptor on the human Jurkat T cell line: evidence for a novel transcript.
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Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.
F G Snijdewint; P Kaliński; E A Wierenga; J D Bos; M L Kapsenberg
J Immunol (1993) 150 (12): 5321–5329.
View articletitled, Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.
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T cell-macrophage cognate interaction in the activation of macrophage effector function by Th2 cells.
R D Stout; J Suttles
J Immunol (1993) 150 (12): 5330–5337.
View articletitled, T cell-macrophage cognate interaction in the activation of macrophage effector function by Th2 cells.
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Anti-CD3-stimulated Ca2+ signal in individual human peripheral T cells. Activation correlates with a sustained increase in intracellular Ca2+1.
M C Wacholtz; P E Lipsky
J Immunol (1993) 150 (12): 5338–5349.
View articletitled, Anti-CD3-stimulated Ca2+ signal in individual human peripheral T cells. Activation correlates with a sustained increase in intracellular Ca2+1.
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A common sequence motif near nonhomologous recombination breakpoints involving Ig sequences.
C L Chou; S L Morrison
J Immunol (1993) 150 (12): 5350–5360.
View articletitled, A common sequence motif near nonhomologous recombination breakpoints involving Ig sequences.
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Syrian and Armenian hamsters differ in serum amyloid A gene expression. Identification of novel Syrian hamster serum amyloid A subtypes.
M C de Beer; F C de Beer; C M Beach; W A Gonnerman; I Carreras; J D Sipe
J Immunol (1993) 150 (12): 5361–5370.
View articletitled, Syrian and Armenian hamsters differ in serum amyloid A gene expression. Identification of novel Syrian hamster serum amyloid A subtypes.
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Simultaneous transfer of four functional genes from the HLA class II region into mammalian cells by fusion with yeast spheroplasts carrying an artificial chromosome.
L A Demmer; D D Chaplin
J Immunol (1993) 150 (12): 5371–5378.
View articletitled, Simultaneous transfer of four functional genes from the HLA class II region into mammalian cells by fusion with yeast spheroplasts carrying an artificial chromosome.
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Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.
T J Fleming; C O'hUigin; T R Malek
J Immunol (1993) 150 (12): 5379–5390.
View articletitled, Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.
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Cloning and expression of immunologically active recombinant Amb a V allergen of short ragweed (Ambrosia artemisiifolia) pollen.
B Ghosh; M P Perry; T Rafnar; D G Marsh
J Immunol (1993) 150 (12): 5391–5399.
View articletitled, Cloning and expression of immunologically active recombinant Amb a V allergen of short ragweed (Ambrosia artemisiifolia) pollen.
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Studies on antigen binding by intact and hinge-deleted chimeric antibodies.
C Horgan; K Brown; S H Pincus
J Immunol (1993) 150 (12): 5400–5407.
View articletitled, Studies on antigen binding by intact and hinge-deleted chimeric antibodies.
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Regulation of the expression of human C epsilon germline transcript. Identification of a novel IL-4 responsive element.
T Ichiki; W Takahashi; T Watanabe
J Immunol (1993) 150 (12): 5408–5417.
View articletitled, Regulation of the expression of human C epsilon germline transcript. Identification of a novel IL-4 responsive element.
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Variable IgH chain enhancer activity in Burkitt's lymphomas suggests an additional, direct mechanism of c-myc deregulation.
V K Jain; J G Judde; E E Max; I T Magrath
J Immunol (1993) 150 (12): 5418–5428.
View articletitled, Variable IgH chain enhancer activity in Burkitt's lymphomas suggests an additional, direct mechanism of c-myc deregulation.
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Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.
M Jones; J L Cordell; A D Beyers; A G Tse; D Y Mason
J Immunol (1993) 150 (12): 5429–5435.
View articletitled, Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.
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Structural comparison and chromosomal localization of the human and mouse IL-13 genes.
A N McKenzie; X Li; D A Largaespada; A Sato; A Kaneda; S M Zurawski; E L Doyle; A Milatovich; U Francke; N G Copeland
J Immunol (1993) 150 (12): 5436–5444.
View articletitled, Structural comparison and chromosomal localization of the human and mouse IL-13 genes.
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CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene.
E Rouvier; M F Luciani; M G Mattéi; F Denizot; P Golstein
J Immunol (1993) 150 (12): 5445–5456.
View articletitled, CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene.
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Differential expression of 13 IgA-heavy chain genes in rabbit lymphoid tissues.
H Spieker-Polet; P C Yam; K L Knight
J Immunol (1993) 150 (12): 5457–5465.
View articletitled, Differential expression of 13 IgA-heavy chain genes in rabbit lymphoid tissues.
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Differentiation of human lambda I variable regions with a monoclonal antibody to a defined, germ-line-encoded idiotope correlates with V lambda Ia chemical structure.
S Suleyman; O Hosono; M Sioud; I Randen; K M Thompson; O Førre; J B Natvig
J Immunol (1993) 150 (12): 5466–5475.
View articletitled, Differentiation of human lambda I variable regions with a monoclonal antibody to a defined, germ-line-encoded idiotope correlates with V lambda Ia chemical structure.
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Leishmania antigens presented by GM-CSF-derived macrophages protect susceptible mice against challenge with Leishmania major.
T M Doherty; R L Coffman
J Immunol (1993) 150 (12): 5476–5483.
View articletitled, Leishmania antigens presented by GM-CSF-derived macrophages protect susceptible mice against challenge with Leishmania major.
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Beta 2-microglobulin-deficient mice can be protected against influenza A infection by vaccination with vaccinia-influenza recombinants expressing hemagglutinin and neuraminidase.
S L Epstein; J A Misplon; C M Lawson; E K Subbarao; M Connors; B R Murphy
J Immunol (1993) 150 (12): 5484–5493.
View articletitled, Beta 2-microglobulin-deficient mice can be protected against influenza A infection by vaccination with vaccinia-influenza recombinants expressing hemagglutinin and neuraminidase.
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Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype.
S Hou; P C Doherty
J Immunol (1993) 150 (12): 5494–5500.
View articletitled, Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype.
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Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy.
P A Sieling; J S Abrams; M Yamamura; P Salgame; B R Bloom; T H Rea; R L Modlin
J Immunol (1993) 150 (12): 5501–5510.
View articletitled, Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy.
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Regulation of IL-5 in onchocerciasis. A critical role for IL-2.
C Steel; T B Nutman
J Immunol (1993) 150 (12): 5511–5518.
View articletitled, Regulation of IL-5 in onchocerciasis. A critical role for IL-2.
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Syngeneic response to SJL follicular center B cell lymphoma (reticular cell sarcoma) cells is primarily in V beta 16+ CD4+ T cells.
V K Tsiagbe; J Asakawa; A Miranda; R M Sutherland; Y Paterson; G J Thorbecke
J Immunol (1993) 150 (12): 5519–5528.
View articletitled, Syngeneic response to SJL follicular center B cell lymphoma (reticular cell sarcoma) cells is primarily in V beta 16+ CD4+ T cells.
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IFN-gamma-mediated antimicrobial response. Indoleamine 2,3-dioxygenase-deficient mutant host cells no longer inhibit intracellular Chlamydia spp. or Toxoplasma growth.
S M Thomas; L F Garrity; C R Brandt; C S Schobert; G S Feng; M W Taylor; J M Carlin; G I Byrne
J Immunol (1993) 150 (12): 5529–5534.
View articletitled, IFN-gamma-mediated antimicrobial response. Indoleamine 2,3-dioxygenase-deficient mutant host cells no longer inhibit intracellular Chlamydia spp. or Toxoplasma growth.
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Transcriptional activation of the macrophage colony-stimulating factor gene by IL-2 is associated with secretion of bioactive macrophage colony-stimulating factor protein by monocytes and involves activation of the transcription factor NF-kappa B.
M A Brach; C Arnold; M Kiehntopf; H J Gruss; F Herrmann
J Immunol (1993) 150 (12): 5535–5543.
View articletitled, Transcriptional activation of the macrophage colony-stimulating factor gene by IL-2 is associated with secretion of bioactive macrophage colony-stimulating factor protein by monocytes and involves activation of the transcription factor NF-kappa B.
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Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells.
J R Bradley; D R Johnson; J S Pober
J Immunol (1993) 150 (12): 5544–5555.
View articletitled, Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells.
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Neutrophil CD14: biochemical properties and role in the secretion of tumor necrosis factor-alpha in response to lipopolysaccharide.
A Haziot; B Z Tsuberi; S M Goyert
J Immunol (1993) 150 (12): 5556–5565.
View articletitled, Neutrophil CD14: biochemical properties and role in the secretion of tumor necrosis factor-alpha in response to lipopolysaccharide.
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Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation.
S Ledoux; N Rebai; A Dagenais; I T Shaw; J Nalbantoglu; R P Sekaly; N R Cashman
J Immunol (1993) 150 (12): 5566–5575.
View articletitled, Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation.
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Th2 cells mediate IL-4-dependent local tissue inflammation.
K M Müller; F Jaunin; I Masouyé; J H Saurat; C Hauser
J Immunol (1993) 150 (12): 5576–5584.
View articletitled, Th2 cells mediate IL-4-dependent local tissue inflammation.
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Inhibition of lung inflammatory reactions in rats by an anti-human IL-8 antibody.
M S Mulligan; M L Jones; M A Bolanowski; M P Baganoff; C L Deppeler; D M Meyers; U S Ryan; P A Ward
J Immunol (1993) 150 (12): 5585–5595.
View articletitled, Inhibition of lung inflammatory reactions in rats by an anti-human IL-8 antibody.
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Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture.
C D Richards; M Shoyab; T J Brown; J Gauldie
J Immunol (1993) 150 (12): 5596–5603.
View articletitled, Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture.
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Microbial superantigens induce NF-kappa B in the human monocytic cell line THP-1.
N S Trede; E Castigli; R S Geha; T Chatila
J Immunol (1993) 150 (12): 5604–5613.
View articletitled, Microbial superantigens induce NF-kappa B in the human monocytic cell line THP-1.
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Molecular, biochemical, and functional characteristics of tumor necrosis factor-alpha produced by human placental cytotrophoblastic cells.
Y Yang; K K Yelavarthi; H L Chen; J L Pace; P F Terranova; J S Hunt
J Immunol (1993) 150 (12): 5614–5624.
View articletitled, Molecular, biochemical, and functional characteristics of tumor necrosis factor-alpha produced by human placental cytotrophoblastic cells.
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IL-1 and transforming growth factor-beta inhibit platelet-derived growth factor-AA binding to osteoblastic cells by reducing platelet-derived growth factor-alpha receptor expression.
Y L Yeh; Y M Kang; M S Chaibi; J F Xie; D T Graves
J Immunol (1993) 150 (12): 5625–5632.
View articletitled, IL-1 and transforming growth factor-beta inhibit platelet-derived growth factor-AA binding to osteoblastic cells by reducing platelet-derived growth factor-alpha receptor expression.
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Antibody-mediated redistribution and shedding of endothelial antigens in the rabbit.
Y Yuzawa; J R Brentjens; J Brett; P R Caldwell; C Esposito; A Fukatsu; G Godman; D Stern; G Andres
J Immunol (1993) 150 (12): 5633–5646.
View articletitled, Antibody-mediated redistribution and shedding of endothelial antigens in the rabbit.
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Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.
J D Ahlers; C D Pendleton; N Dunlop; A Minassian; P L Nara; J A Berzofsky
J Immunol (1993) 150 (12): 5647–5665.
View articletitled, Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.
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Identification of a major encephalitogenic epitope of proteolipid protein (residues 56-70) for the induction of experimental allergic encephalomyelitis in Biozzi AB/H and nonobese diabetic mice.
S Amor; D Baker; N Groome; J L Turk
J Immunol (1993) 150 (12): 5666–5672.
View articletitled, Identification of a major encephalitogenic epitope of proteolipid protein (residues 56-70) for the induction of experimental allergic encephalomyelitis in Biozzi AB/H and nonobese diabetic mice.
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Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations.
M C Gagnerault; P Touraine; W Savino; P A Kelly; M Dardenne
J Immunol (1993) 150 (12): 5673–5681.
View articletitled, Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations.
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Characterization of T cells infiltrating the heart in rats with experimental autoimmune myocarditis. Their similarity to extrathymic T cells in mice and the site of proliferation.
H Hanawa; M Tsuchida; Y Matsumoto; H Watanabe; T Abo; H Sekikawa; M Kodama; S Zhang; T Izumi; A Shibata
J Immunol (1993) 150 (12): 5682–5695.
View articletitled, Characterization of T cells infiltrating the heart in rats with experimental autoimmune myocarditis. Their similarity to extrathymic T cells in mice and the site of proliferation.
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Overexpression of LFA-1 and ICAM-1 in Down syndrome thymus. Implications for abnormal thymocyte maturation.
M Murphy; R M Insoft; L Pike-Nobile; K S Derbin; L B Epstein
J Immunol (1993) 150 (12): 5696–5703.
View articletitled, Overexpression of LFA-1 and ICAM-1 in Down syndrome thymus. Implications for abnormal thymocyte maturation.
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Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death.
L G Radvanyi; G B Mills; R G Miller
J Immunol (1993) 150 (12): 5704–5715.
View articletitled, Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death.
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Usage of T cell receptor beta-chain variable gene is highly restricted at the site of inflammation in murine autoimmune uveitis.
N A Rao; Y M Naidu; R Bell; J W Lindsey; G Pararajasegaram; Y Sun; L Steinman
J Immunol (1993) 150 (12): 5716–5721.
View articletitled, Usage of T cell receptor beta-chain variable gene is highly restricted at the site of inflammation in murine autoimmune uveitis.
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A peptide variant of an arthritis-related T cell epitope induces T cells that recognize this epitope as a synthetic peptide but not in its naturally processed form.
M H Wauben; R van der Zee; I Joosten; C J Boog; A M van Dijk; M C Holewijn; R H Meloen; W van Eden
J Immunol (1993) 150 (12): 5722–5730.
View articletitled, A peptide variant of an arthritis-related T cell epitope induces T cells that recognize this epitope as a synthetic peptide but not in its naturally processed form.
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ERRATA

Genetic mechanisms for dominant VH gene expression: the VHB512 Gene
C Fernandez
J Immunol (1993) 150 (12): 5731.
View articletitled, Genetic mechanisms for dominant VH gene expression: the VHB512 Gene
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Unexpected Effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog
WA Kuziel; G Ju; TA Grdina; WC Greene
J Immunol (1993) 150 (12): 5731.
View articletitled, Unexpected Effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog
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Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell
R Wang; KM Murphy; DY Loh; C Weaver; JH Russel
J Immunol (1993) 150 (12): 5732.
View articletitled, Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell
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  • Online ISSN 1550-6606
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