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Volume 154, Issue 6
15 March 1995
Issue Cover
ISSN 0022-1767
EISSN 1550-6606
In this Issue

ARTICLES

Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes.
N Burdin; C Van Kooten; L Galibert; J S Abrams; J Wijdenes; J Banchereau; F Rousset
J Immunol (1995) 154 (6): 2533–2544.
View articletitled, Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes.
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DMA and DMB are the only genes in the class II region of the human MHC needed for class II-associated antigen processing.
S Ceman; R A Rudersdorf; J M Petersen; R DeMars
J Immunol (1995) 154 (6): 2545–2556.
View articletitled, DMA and DMB are the only genes in the class II region of the human MHC needed for class II-associated antigen processing.
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Intraembryonic origin of hepatic hematopoiesis in Xenopus laevis.
X D Chen; J B Turpen
J Immunol (1995) 154 (6): 2557–2567.
View articletitled, Intraembryonic origin of hepatic hematopoiesis in Xenopus laevis.
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Hybrid and allogeneic resistance to T cell grafts mediated by murine NK and CD8+ T cells.
C Davenport; A Haile; V Kumar; M Bennett
J Immunol (1995) 154 (6): 2568–2577.
View articletitled, Hybrid and allogeneic resistance to T cell grafts mediated by murine NK and CD8+ T cells.
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IL-12 inhibits IL-4 synthesis in keyhole limpet hemocyanin-primed CD4+ T cells through an effect on antigen-presenting cells.
R H DeKruyff; Y Fang; S F Wolf; D T Umetsu
J Immunol (1995) 154 (6): 2578–2587.
View articletitled, IL-12 inhibits IL-4 synthesis in keyhole limpet hemocyanin-primed CD4+ T cells through an effect on antigen-presenting cells.
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Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection.
J P Dutz; C J Ong; J Marth; H S Teh
J Immunol (1995) 154 (6): 2588–2599.
View articletitled, Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection.
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Selective expansion followed by profound deletion of mature V beta 8.3+ T cells in vivo after exposure to the superantigenic lectin Urtica dioica agglutinin.
A Galelli; M Delcourt; M C Wagner; W Peumans; P Truffa-Bachi
J Immunol (1995) 154 (6): 2600–2611.
View articletitled, Selective expansion followed by profound deletion of mature V beta 8.3+ T cells in vivo after exposure to the superantigenic lectin Urtica dioica agglutinin.
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Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation.
R Q Hintzen; S M Lens; K Lammers; H Kuiper; M P Beckmann; R A van Lier
J Immunol (1995) 154 (6): 2612–2623.
View articletitled, Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation.
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A cascade of cytokines is responsible for IL-9 expression in human T cells. Involvement of IL-2, IL-4, and IL-10.
F A Houssiau; L Schandené; M Stevens; C Cambiaso; M Goldman; J van Snick; J C Renauld
J Immunol (1995) 154 (6): 2624–2630.
View articletitled, A cascade of cytokines is responsible for IL-9 expression in human T cells. Involvement of IL-2, IL-4, and IL-10.
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NK cell recognition of MHC class I. NK cells are sensitive to peptide-binding groove and surface alpha-helical mutations that affect T cells.
Z B Kurago; K D Smith; C T Lutz
J Immunol (1995) 154 (6): 2631–2641.
View articletitled, NK cell recognition of MHC class I. NK cells are sensitive to peptide-binding groove and surface alpha-helical mutations that affect T cells.
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Autologous rat myelin basic protein is a partial agonist that is converted into a full antagonist upon blockade of CD4. Evidence for the integration of efficacious and nonefficacious signals during T cell antigen recognition.
M D Mannie; J M Rosser; G A White
J Immunol (1995) 154 (6): 2642–2654.
View articletitled, Autologous rat myelin basic protein is a partial agonist that is converted into a full antagonist upon blockade of CD4. Evidence for the integration of efficacious and nonefficacious signals during T cell antigen recognition.
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Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
A M Miltenburg; S Lacraz; H G Welgus; J M Dayer
J Immunol (1995) 154 (6): 2655–2667.
View articletitled, Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
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Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression.
R S Mitra; T A Judge; F O Nestle; L A Turka; B J Nickoloff
J Immunol (1995) 154 (6): 2668–2677.
View articletitled, Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression.
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Analysis of the intra-epithelial lymphocyte compartment in SCID mice that received co-isogenic CD4+ T cells. Evidence that mature post-thymic CD4+ T cells can be induced to express CD8 alpha in vivo.
P J Morrissey; K Charrier; D A Horovitz; F A Fletcher; J D Watson
J Immunol (1995) 154 (6): 2678–2686.
View articletitled, Analysis of the intra-epithelial lymphocyte compartment in SCID mice that received co-isogenic CD4+ T cells. Evidence that mature post-thymic CD4+ T cells can be induced to express CD8 alpha in vivo.
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Anti-IL-4 antibody prevents graft-versus-host disease in mice after bone marrow transplantation. The IgE allotype is an important marker of graft-versus-host disease.
C Ushiyama; T Hirano; H Miyajima; K Okumura; Z Ovary; H Hashimoto
J Immunol (1995) 154 (6): 2687–2696.
View articletitled, Anti-IL-4 antibody prevents graft-versus-host disease in mice after bone marrow transplantation. The IgE allotype is an important marker of graft-versus-host disease.
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Successive generation of antigen-presenting, dendritic cell lines from murine epidermis.
S Xu; K Ariizumi; G Caceres-Dittmar; D Edelbaum; K Hashimoto; P R Bergstresser; A Takashima
J Immunol (1995) 154 (6): 2697–2705.
View articletitled, Successive generation of antigen-presenting, dendritic cell lines from murine epidermis.
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Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing.
I Cascino; G Fiucci; G Papoff; G Ruberti
J Immunol (1995) 154 (6): 2706–2713.
View articletitled, Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing.
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Molecular cloning of a cDNA clone encoding a phosphoprotein component related to the Ig receptor-mediated signal transduction.
S Inui; K Kuwahara; J Mizutani; K Maeda; T Kawai; H Nakayasu; N Sakaguchi
J Immunol (1995) 154 (6): 2714–2723.
View articletitled, Molecular cloning of a cDNA clone encoding a phosphoprotein component related to the Ig receptor-mediated signal transduction.
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Role of ETS1 in IL-2 gene expression.
V Romano-Spica; P Georgiou; H Suzuki; T S Papas; N K Bhat
J Immunol (1995) 154 (6): 2724–2732.
View articletitled, Role of ETS1 in IL-2 gene expression.
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CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.
M Shirai; T Arichi; M Nishioka; T Nomura; K Ikeda; K Kawanishi; V H Engelhard; S M Feinstone; J A Berzofsky
J Immunol (1995) 154 (6): 2733–2742.
View articletitled, CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.
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Structure of the mouse CD72 (Lyb-2) gene and its alternatively spliced transcripts.
H Ying; E Nakayama; W H Robinson; J R Parnes
J Immunol (1995) 154 (6): 2743–2752.
View articletitled, Structure of the mouse CD72 (Lyb-2) gene and its alternatively spliced transcripts.
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Involvement of IFN-gamma in Bacillus Calmette-Guérin-induced but not in tumor-induced sensitization to TNF-induced lethality.
A Cauwels; P Brouckaert; J Grooten; S Huang; M Aguet; W Fiers
J Immunol (1995) 154 (6): 2753–2763.
View articletitled, Involvement of IFN-gamma in Bacillus Calmette-Guérin-induced but not in tumor-induced sensitization to TNF-induced lethality.
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Activation of IFN-alpha, IFN-gamma, MxA, and IFN regulatory factor 1 genes in influenza A virus-infected human peripheral blood mononuclear cells.
T Ronni; T Sareneva; J Pirhonen; I Julkunen
J Immunol (1995) 154 (6): 2764–2774.
View articletitled, Activation of IFN-alpha, IFN-gamma, MxA, and IFN regulatory factor 1 genes in influenza A virus-infected human peripheral blood mononuclear cells.
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IL-7 in the cell-mediated immune response to a human pathogen.
P A Sieling; L Sakimura; K Uyemura; M Yamamura; J Oliveros; B J Nickoloff; T H Rea; R L Modlin
J Immunol (1995) 154 (6): 2775–2783.
View articletitled, IL-7 in the cell-mediated immune response to a human pathogen.
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Induction of protective polyclonal antibodies by immunization with a Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine.
R Wang; Y Charoenvit; G Corradin; R Porrozzi; R L Hunter; G Glenn; C R Alving; P Church; S L Hoffman
J Immunol (1995) 154 (6): 2784–2793.
View articletitled, Induction of protective polyclonal antibodies by immunization with a Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine.
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Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 costimulatory molecules.
G Yang; K E Hellström; I Hellström; L Chen
J Immunol (1995) 154 (6): 2794–2800.
View articletitled, Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 costimulatory molecules.
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Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions.
L F Brown; S M Olbricht; B Berse; R W Jackman; G Matsueda; K A Tognazzi; E J Manseau; H F Dvorak; L Van de Water
J Immunol (1995) 154 (6): 2801–2807.
View articletitled, Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions.
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Evidence for the involvement of arginine 462 and the flanking sequence of human C4 beta-chain in mediating C5 binding to the C4b subcomponent of the classical complement pathway C5 convertase.
R O Ebanks; D E Isenman
J Immunol (1995) 154 (6): 2808–2820.
View articletitled, Evidence for the involvement of arginine 462 and the flanking sequence of human C4 beta-chain in mediating C5 binding to the C4b subcomponent of the classical complement pathway C5 convertase.
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ATP induces the release of IL-1 from LPS-primed cells in vivo.
R J Griffiths; E J Stam; J T Downs; I G Otterness
J Immunol (1995) 154 (6): 2821–2828.
View articletitled, ATP induces the release of IL-1 from LPS-primed cells in vivo.
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Identification of complement receptor type 1-related proteins on primate erythrocytes.
M W Nickells; V B Subramanian; L Clemenza; J P Atkinson
J Immunol (1995) 154 (6): 2829–2837.
View articletitled, Identification of complement receptor type 1-related proteins on primate erythrocytes.
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IL-4 induction of VCAM-1 on endothelial cells involves activation of a protein tyrosine kinase.
R L Palmer-Crocker; J S Pober
J Immunol (1995) 154 (6): 2838–2845.
View articletitled, IL-4 induction of VCAM-1 on endothelial cells involves activation of a protein tyrosine kinase.
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Class II MHC gene expression in microglia. Regulation by the cytokines IFN-gamma, TNF-alpha, and TGF-beta.
R B Panek; E N Benveniste
J Immunol (1995) 154 (6): 2846–2854.
View articletitled, Class II MHC gene expression in microglia. Regulation by the cytokines IFN-gamma, TNF-alpha, and TGF-beta.
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Human heart mast cells. Isolation, purification, ultrastructure, and immunologic characterization.
V Patella; I Marinò; B Lampärter; E Arbustini; M Adt; G Marone
J Immunol (1995) 154 (6): 2855–2865.
View articletitled, Human heart mast cells. Isolation, purification, ultrastructure, and immunologic characterization.
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Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages.
J D Radolf; L L Arndt; D R Akins; L L Curetty; M E Levi; Y Shen; L S Davis; M V Norgard
J Immunol (1995) 154 (6): 2866–2877.
View articletitled, Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages.
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Prostaglandin E2 release triggered by phagocytosis of latex particles. A distinct association with prostaglandin synthase isozymes in bone marrow macrophages.
Y Shibata
J Immunol (1995) 154 (6): 2878–2887.
View articletitled, Prostaglandin E2 release triggered by phagocytosis of latex particles. A distinct association with prostaglandin synthase isozymes in bone marrow macrophages.
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CD50 (ICAM-3) is phosphorylated on tyrosine and is associated with tyrosine kinase activity in human neutrophils.
K M Skubitz; K Ahmed; K D Campbell; A P Skubitz
J Immunol (1995) 154 (6): 2888–2895.
View articletitled, CD50 (ICAM-3) is phosphorylated on tyrosine and is associated with tyrosine kinase activity in human neutrophils.
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Molecular basis for a familial defect in phagocyte expression of IgG receptor I (CD64).
J G van de Winkel; T P de Wit; L K Ernst; P J Capel; J L Ceuppens
J Immunol (1995) 154 (6): 2896–2903.
View articletitled, Molecular basis for a familial defect in phagocyte expression of IgG receptor I (CD64).
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Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.
P Vandenabeele; W Declercq; B Vanhaesebroeck; J Grooten; W Fiers
J Immunol (1995) 154 (6): 2904–2913.
View articletitled, Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.
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Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.
Y Vodovotz; D Russell; Q W Xie; C Bogdan; C Nathan
J Immunol (1995) 154 (6): 2914–2925.
View articletitled, Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.
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Expression of TNF receptors by T cells and membrane TNF-alpha by alveolar macrophages suggests a role for TNF-alpha in the regulation of the local immune responses in the lung of HIV-1-infected patients.
C Agostini; R Zambello; L Trentin; A Cerutti; C Enthammer; M Facco; A Milani; R Sancetta; S Garbisa; G Semenzato
J Immunol (1995) 154 (6): 2928–2938.
View articletitled, Expression of TNF receptors by T cells and membrane TNF-alpha by alveolar macrophages suggests a role for TNF-alpha in the regulation of the local immune responses in the lung of HIV-1-infected patients.
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A 12-kDa protein of Mycobacterium tuberculosis protects mice against experimental autoimmune encephalomyelitis. Protection in the absence of shared T cell epitopes with encephalitogenic proteins.
A Ben-Nun; I Mendel; G Sappler; N Kerlero de Rosbo
J Immunol (1995) 154 (6): 2939–2948.
View articletitled, A 12-kDa protein of Mycobacterium tuberculosis protects mice against experimental autoimmune encephalomyelitis. Protection in the absence of shared T cell epitopes with encephalitogenic proteins.
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Anti-TNF-alpha treatment down-regulates the expression of fibronectin and decreases cellular infiltration of cardiac allografts in rats.
A J Coito; J Binder; L F Brown; M de Sousa; L Van de Water; J W Kupiec-Weglinski
J Immunol (1995) 154 (6): 2949–2958.
View articletitled, Anti-TNF-alpha treatment down-regulates the expression of fibronectin and decreases cellular infiltration of cardiac allografts in rats.
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Patterns of cytokine secretion by autoreactive proteolipid protein-specific T cell clones during the course of multiple sclerosis.
J Correale; W Gilmore; M McMillan; S Li; K McCarthy; T Le; L P Weiner
J Immunol (1995) 154 (6): 2959–2968.
View articletitled, Patterns of cytokine secretion by autoreactive proteolipid protein-specific T cell clones during the course of multiple sclerosis.
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Peri-islet infiltrates of young non-obese diabetic mice display restricted TCR beta-chain diversity.
K A Galley; J S Danska
J Immunol (1995) 154 (6): 2969–2982.
View articletitled, Peri-islet infiltrates of young non-obese diabetic mice display restricted TCR beta-chain diversity.
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Molecular mimicry, anti-coxsackievirus B3 neutralizing monoclonal antibodies, and myocarditis.
C J Gauntt; H M Arizpe; A L Higdon; H J Wood; D F Bowers; M M Rozek; R Crawley
J Immunol (1995) 154 (6): 2983–2995.
View articletitled, Molecular mimicry, anti-coxsackievirus B3 neutralizing monoclonal antibodies, and myocarditis.
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HIV-1 down-regulates CD4 costimulation of TCR/CD3-directed tyrosine phosphorylation through CD4/p56lck dissociation.
S B Kanner; O K Haffar
J Immunol (1995) 154 (6): 2996–3005.
View articletitled, HIV-1 down-regulates CD4 costimulation of TCR/CD3-directed tyrosine phosphorylation through CD4/p56lck dissociation.
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Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression.
D M Nelson; K A Butters; M L Markert; N L Reinsmoen; R S McIvor
J Immunol (1995) 154 (6): 3006–3014.
View articletitled, Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression.
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Existence of a soluble form of CD50 (intercellular adhesion molecule-3) produced upon human lymphocyte activation. Present in normal human serum and levels are increased in the serum of systemic lupus erythematosus patients.
M R Pino-Otín; O Viñas; M A de la Fuente; M Juan; J Font; M Torradeflot; L Pallarés; F Lozano; J Alberola-Ila; J Martorell
J Immunol (1995) 154 (6): 3015–3024.
View articletitled, Existence of a soluble form of CD50 (intercellular adhesion molecule-3) produced upon human lymphocyte activation. Present in normal human serum and levels are increased in the serum of systemic lupus erythematosus patients.
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Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo.
R L Yung; J Quddus; C E Chrisp; K J Johnson; B C Richardson
J Immunol (1995) 154 (6): 3025–3035.
View articletitled, Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo.
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