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Volume 157, Issue 2
15 July 1996
Issue Cover
ISSN 0022-1767
EISSN 1550-6606
In this Issue

CUTTING EDGE

Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic.
J E Gretz; E P Kaldjian; A O Anderson; S Shaw
J Immunol (1996) 157 (2): 495–499.
View articletitled, Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic.
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Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor.
D E Danley; T H Chuang; G M Bokoch
J Immunol (1996) 157 (2): 500–503.
View articletitled, Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor.
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ARTICLES

The weak CD8+ CTL response to an influenza hemagglutinin epitope reflects limited T cell availability.
W Cao; B A Myers-Powell; T J Braciale
J Immunol (1996) 157 (2): 505–511.
View articletitled, The weak CD8+ CTL response to an influenza hemagglutinin epitope reflects limited T cell availability.
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Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.
M Castedo; T Hirsch; S A Susin; N Zamzami; P Marchetti; A Macho; G Kroemer
J Immunol (1996) 157 (2): 512–521.
View articletitled, Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.
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IFN-alpha induces autoimmune T cells through the induction of intracellular adhesion molecule-1 and B7.2.
D Chakrabarti; B Hultgren; T A Stewart
J Immunol (1996) 157 (2): 522–528.
View articletitled, IFN-alpha induces autoimmune T cells through the induction of intracellular adhesion molecule-1 and B7.2.
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T cell regulation in adult transplantation tolerance.
J D Davies; G Martin; J Phillips; S E Marshall; S P Cobbold; H Waldmann
J Immunol (1996) 157 (2): 529–533.
View articletitled, T cell regulation in adult transplantation tolerance.
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Tyrosine phosphorylation of Shc is not required for proliferation or viability signaling by granulocyte-macrophage colony-stimulating factor in hematopoietic cell lines.
M Durstin; R C Inhorn; J D Griffin
J Immunol (1996) 157 (2): 534–540.
View articletitled, Tyrosine phosphorylation of Shc is not required for proliferation or viability signaling by granulocyte-macrophage colony-stimulating factor in hematopoietic cell lines.
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Type I (CD64) and type II (CD32) Fc gamma receptor-mediated phagocytosis by human blood dendritic cells.
N A Fanger; K Wardwell; L Shen; T F Tedder; P M Guyre
J Immunol (1996) 157 (2): 541–548.
View articletitled, Type I (CD64) and type II (CD32) Fc gamma receptor-mediated phagocytosis by human blood dendritic cells.
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Regulation of the B cell response to T-dependent antigens by classical pathway complement.
M B Fischer; M Ma; S Goerg; X Zhou; J Xia; O Finco; S Han; G Kelsoe; R G Howard; T L Rothstein; E Kremmer; F S Rosen; M C Carroll
J Immunol (1996) 157 (2): 549–556.
View articletitled, Regulation of the B cell response to T-dependent antigens by classical pathway complement.
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Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity.
G P Geba; W Ptak; G M Anderson; V Paliwal; R E Ratzlaff; J Levin; P W Askenase
J Immunol (1996) 157 (2): 557–565.
View articletitled, Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity.
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Th1 development of naive CD4+ T cells is inhibited by co-activation with anti-CD4 monoclonal antibodies.
S Goedert; T Germann; P Hoehn; S Koelsch; N Palm; E Rüde; E Schmitt
J Immunol (1996) 157 (2): 566–573.
View articletitled, Th1 development of naive CD4+ T cells is inhibited by co-activation with anti-CD4 monoclonal antibodies.
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Gamma delta TCR+ hybridomas derived from mice preimmunized via the portal vein adoptively transfer increased skin allograft survival in vivo.
R M Gorczynski; Z Cohen; Y Leung; Z Chen
J Immunol (1996) 157 (2): 574–581.
View articletitled, Gamma delta TCR+ hybridomas derived from mice preimmunized via the portal vein adoptively transfer increased skin allograft survival in vivo.
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The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation.
M Inobe; N Aoki; P S Linsley; J A Ledbetter; R Abe; M Murakami; T Uede
J Immunol (1996) 157 (2): 582–588.
View articletitled, The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation.
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Differential effect of the immunomodulator AS101 on B7-1 and B7-2 costimulatory molecules: role in the antitumoral effects of AS101.
Y Kalechman; B Sredni
J Immunol (1996) 157 (2): 589–597.
View articletitled, Differential effect of the immunomodulator AS101 on B7-1 and B7-2 costimulatory molecules: role in the antitumoral effects of AS101.
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Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse.
V M Lentz; M P Cancro; F E Nashold; C E Hayes
J Immunol (1996) 157 (2): 598–606.
View articletitled, Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse.
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Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.
D Maurer; S Fiebiger; C Ebner; B Reininger; G F Fischer; S Wichlas; M H Jouvin; M Schmitt-Egenolf; D Kraft; J P Kinet; G Stingl
J Immunol (1996) 157 (2): 607–616.
View articletitled, Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.
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Chemical denaturation and modification of ovalbumin alters its dependence on ubiquitin conjugation for class I antigen presentation.
M T Michalek; E P Grant; K L Rock
J Immunol (1996) 157 (2): 617–624.
View articletitled, Chemical denaturation and modification of ovalbumin alters its dependence on ubiquitin conjugation for class I antigen presentation.
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TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation.
G Muralidhar; S Koch; H E Broome; S L Swain
J Immunol (1996) 157 (2): 625–635.
View articletitled, TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation.
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CD28 costimulation prevents cell death during primary T cell activation.
P J Noel; L H Boise; J M Green; C B Thompson
J Immunol (1996) 157 (2): 636–642.
View articletitled, CD28 costimulation prevents cell death during primary T cell activation.
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The effect of IL-2 treatment on transcriptional attenuation in proto-oncogenes pim-1 and c-myb in human thymic blast cells.
F Rohwer; S Todd; K L McGuire
J Immunol (1996) 157 (2): 643–649.
View articletitled, The effect of IL-2 treatment on transcriptional attenuation in proto-oncogenes pim-1 and c-myb in human thymic blast cells.
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Introduction of exogenous antigens into the MHC class I processing and presentation pathway by Drosophila antennapedia homeodomain primes cytotoxic T cells in vivo.
M P Schutze-Redelmeier; H Gournier; F Garcia-Pons; M Moussa; A H Joliot; M Volovitch; A Prochiantz; F A Lemonnier
J Immunol (1996) 157 (2): 650–655.
View articletitled, Introduction of exogenous antigens into the MHC class I processing and presentation pathway by Drosophila antennapedia homeodomain primes cytotoxic T cells in vivo.
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p70 S6 kinase sensitivity to rapamycin is eliminated by amino acid substitution of Thr229.
H Sugiyama; P Papst; E W Gelfand; N Terada
J Immunol (1996) 157 (2): 656–660.
View articletitled, p70 S6 kinase sensitivity to rapamycin is eliminated by amino acid substitution of Thr229.
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Characterization of a T cell line specific to an anti-Id antibody related to the carbohydrate antigen, sialyl SSEA-1, and the immundominant T cell antigenic site of the antibody.
K Tsuyuoka; K Yago; K Hirashima; S Ando; N Hanai; H Saito; K M Yamasaki; K Takahashi; Y Fukuda; K Nakao; R Kannagi
J Immunol (1996) 157 (2): 661–669.
View articletitled, Characterization of a T cell line specific to an anti-Id antibody related to the carbohydrate antigen, sialyl SSEA-1, and the immundominant T cell antigenic site of the antibody.
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Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone.
K Udaka; K H Wiesmüller; S Kienle; G Jung; P Walden
J Immunol (1996) 157 (2): 670–678.
View articletitled, Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone.
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A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule.
M Vergelli; H Le; J M van Noort; S Dhib-Jalbut; H McFarland; R Martin
J Immunol (1996) 157 (2): 679–688.
View articletitled, A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule.
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IL-12 is a central mediator of acute graft-versus-host disease in mice.
E Williamson; P Garside; J A Bradley; A M Mowat
J Immunol (1996) 157 (2): 689–699.
View articletitled, IL-12 is a central mediator of acute graft-versus-host disease in mice.
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Specific inhibition of T lymphocyte coactivation by triggering integrin beta 1 reveals convergence of beta 1, beta 2, and beta 7 signaling pathways.
D G Woodside; T K Teague; B W McIntyre
J Immunol (1996) 157 (2): 700–706.
View articletitled, Specific inhibition of T lymphocyte coactivation by triggering integrin beta 1 reveals convergence of beta 1, beta 2, and beta 7 signaling pathways.
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Requirement of Fas(CD95), CD45, and CD11a/CD18 in monocyte-dependent apoptosis of human T cells.
M X Wu; Z Ao; M Hegen; C Morimoto; S F Schlossman
J Immunol (1996) 157 (2): 707–713.
View articletitled, Requirement of Fas(CD95), CD45, and CD11a/CD18 in monocyte-dependent apoptosis of human T cells.
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Non-T cell-derived IL-4 plays an important role in IgE production induced by antigen resensitization and is resistant to FK506.
M Yamashita; M Yamaoka; N Seki; T Fujii
J Immunol (1996) 157 (2): 714–719.
View articletitled, Non-T cell-derived IL-4 plays an important role in IgE production induced by antigen resensitization and is resistant to FK506.
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Molecular mimicry between an immunodominant amino acid motif on the 47-kDa lipoprotein of Treponema pallidum (Tpp47) and multiple repeats of analogous sequences in fibronectin.
R E Baughn; A Jiang; R Abraham; V Ottmers; D M Musher
J Immunol (1996) 157 (2): 720–731.
View articletitled, Molecular mimicry between an immunodominant amino acid motif on the 47-kDa lipoprotein of Treponema pallidum (Tpp47) and multiple repeats of analogous sequences in fibronectin.
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High affinity antibodies against Lex and sialyl Lex from a phage display library.
Q Dinh; N P Weng; M Kiso; H Ishida; A Hasegawa; D M Marcus
J Immunol (1996) 157 (2): 732–738.
View articletitled, High affinity antibodies against Lex and sialyl Lex from a phage display library.
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Determinants of polyreactivity in a large panel of recombinant human antibodies from HIV-1 infection.
H J Ditzel; K Itoh; D R Burton
J Immunol (1996) 157 (2): 739–749.
View articletitled, Determinants of polyreactivity in a large panel of recombinant human antibodies from HIV-1 infection.
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Lack of association of secretory component with IgA in J chain-deficient mice.
B A Hendrickson; L Rindisbacher; B Corthesy; D Kendall; D A Waltz; M R Neutra; J G Seidman
J Immunol (1996) 157 (2): 750–754.
View articletitled, Lack of association of secretory component with IgA in J chain-deficient mice.
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A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak.
C A Nelson; N J Viner; S P Young; S J Petzold; E R Unanue
J Immunol (1996) 157 (2): 755–762.
View articletitled, A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak.
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Somatically mutated B cell pool provides precursors for insulin antibodies.
J W Thomas; C Hulbert
J Immunol (1996) 157 (2): 763–771.
View articletitled, Somatically mutated B cell pool provides precursors for insulin antibodies.
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Isolation of a neutralizing human RSV antibody from a dominant, non-neutralizing immune repertoire by epitope-blocked panning.
P Tsui; M A Tornetta; R S Ames; B C Bankosky; S Griego; C Silverman; T Porter; G Moore; R W Sweet
J Immunol (1996) 157 (2): 772–780.
View articletitled, Isolation of a neutralizing human RSV antibody from a dominant, non-neutralizing immune repertoire by epitope-blocked panning.
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Enhanced growth of murine melanoma in ultraviolet-irradiated skin is associated with local inhibition of immune effector mechanisms.
C K Donawho; H K Muller; C D Bucana; M L Kripke
J Immunol (1996) 157 (2): 781–786.
View articletitled, Enhanced growth of murine melanoma in ultraviolet-irradiated skin is associated with local inhibition of immune effector mechanisms.
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Multiple HLA-A alleles can present an immunodominant peptide of the human melanoma antigen Melan-A/MART-1 to a peptide-specific HLA-A*0201+ cytotoxic T cell line.
K Fleischhauer; S Tanzarella; H J Wallny; C Bordignon; C Traversari
J Immunol (1996) 157 (2): 787–797.
View articletitled, Multiple HLA-A alleles can present an immunodominant peptide of the human melanoma antigen Melan-A/MART-1 to a peptide-specific HLA-A*0201+ cytotoxic T cell line.
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In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.
R T Gazzinelli; M Wysocka; S Hieny; T Scharton-Kersten; A Cheever; R Kühn; W Müller; G Trinchieri; A Sher
J Immunol (1996) 157 (2): 798–805.
View articletitled, In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.
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Calpain is the target antigen of a Th1 clone that transfers protective immunity against Schistosoma mansoni.
D Jankovic; L Aslund; I P Oswald; P Caspar; C Champion; E Pearce; J E Coligan; M Strand; A Sher; S L James
J Immunol (1996) 157 (2): 806–814.
View articletitled, Calpain is the target antigen of a Th1 clone that transfers protective immunity against Schistosoma mansoni.
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Exacerbated viral hepatitis in IFN-gamma receptor-deficient mice is not suppressed by IL-12.
V E Schijns; C M Wierda; M van Hoeij; M C Horzinek
J Immunol (1996) 157 (2): 815–821.
View articletitled, Exacerbated viral hepatitis in IFN-gamma receptor-deficient mice is not suppressed by IL-12.
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Recombinant polyepitope vaccines for the delivery of multiple CD8 cytotoxic T cell epitopes.
S A Thomson; S L Elliott; M A Sherritt; K W Sproat; B E Coupar; A A Scalzo; C A Forbes; A M Ladhams; X Y Mo; R A Tripp; P C Doherty; D J Moss; A Suhrbier
J Immunol (1996) 157 (2): 822–826.
View articletitled, Recombinant polyepitope vaccines for the delivery of multiple CD8 cytotoxic T cell epitopes.
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Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication.
L Q Vieira; M Goldschmidt; M Nashleanas; K Pfeffer; T Mak; P Scott
J Immunol (1996) 157 (2): 827–835.
View articletitled, Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication.
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Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity.
M E Weijtens; R A Willemsen; D Valerio; K Stam; R L Bolhuis
J Immunol (1996) 157 (2): 836–843.
View articletitled, Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity.
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Counter-receptors on human basophils for endothelial cell adhesion molecules.
B S Bochner; S A Sterbinsky; M Briskin; S S Saini; D W MacGlashan, Jr
J Immunol (1996) 157 (2): 844–850.
View articletitled, Counter-receptors on human basophils for endothelial cell adhesion molecules.
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Human fibroblasts express functional IL-2 receptors formed by the IL-2R alpha- and beta-chain subunits: association of IL-2 binding with secretion of the monocyte chemoattractant protein-1.
H J Gruss; C Scott; B J Rollins; M A Brach; F Herrmann
J Immunol (1996) 157 (2): 851–857.
View articletitled, Human fibroblasts express functional IL-2 receptors formed by the IL-2R alpha- and beta-chain subunits: association of IL-2 binding with secretion of the monocyte chemoattractant protein-1.
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Neutrophil adhesion to 24-hour IL-1-stimulated endothelial cells under flow conditions.
D A Jones; C W Smith; L J Picker; L V McIntire
J Immunol (1996) 157 (2): 858–863.
View articletitled, Neutrophil adhesion to 24-hour IL-1-stimulated endothelial cells under flow conditions.
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IFN-gamma-induced MHC class II gene expression is suppressed in endothelial cells by dextran sulfate.
R H Lian; G J Kotwal; S R Wellhausen; L A Hunt; D E Justus
J Immunol (1996) 157 (2): 864–873.
View articletitled, IFN-gamma-induced MHC class II gene expression is suppressed in endothelial cells by dextran sulfate.
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Human Thy-1 is cytokine-inducible on vascular endothelial cells and is a signaling molecule regulated by protein kinase C.
J C Mason; H Yarwood; A Tárnok; K Sugars; A A Harrison; P J Robinson; D O Haskard
J Immunol (1996) 157 (2): 874–883.
View articletitled, Human Thy-1 is cytokine-inducible on vascular endothelial cells and is a signaling molecule regulated by protein kinase C.
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Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.
A Sahu; B K Kay; J D Lambris
J Immunol (1996) 157 (2): 884–891.
View articletitled, Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.
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Stimulus-specific inhibition of intracellular adhesion molecule-1 gene expression by TGF-beta.
P Shrikant; S J Lee; I Kalvakolanu; R M Ransohoff; E N Benveniste
J Immunol (1996) 157 (2): 892–900.
View articletitled, Stimulus-specific inhibition of intracellular adhesion molecule-1 gene expression by TGF-beta.
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Accelerated amyloid deposition in mice treated with the aspartic protease inhibitor, pepstatin.
T Yamada; J Liepnieks; M D Benson; B Kluve-Beckerman
J Immunol (1996) 157 (2): 901–907.
View articletitled, Accelerated amyloid deposition in mice treated with the aspartic protease inhibitor, pepstatin.
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Role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis.
C Agostini; L Trentin; M Facco; R Sancetta; A Cerutti; C Tassinari; L Cimarosto; F Adami; A Cipriani; R Zambello; G Semenzato
J Immunol (1996) 157 (2): 910–918.
View articletitled, Role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis.
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Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55.
M Ichikawa; T G Johns; J Liu; C C Bernard
J Immunol (1996) 157 (2): 919–926.
View articletitled, Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55.
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Cloning and analysis of IgG kappa and IgG lambda anti-thyroglobulin autoantibodies from a patient with Hashimoto's thyroiditis: evidence for in vivo antigen-driven repertoire selection.
R S McIntosh; M S Asghar; P F Watson; E H Kemp; A P Weetman
J Immunol (1996) 157 (2): 927–935.
View articletitled, Cloning and analysis of IgG kappa and IgG lambda anti-thyroglobulin autoantibodies from a patient with Hashimoto's thyroiditis: evidence for in vivo antigen-driven repertoire selection.
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IL-10 modulates formation of osteoclasts in murine hemopoietic cultures.
J M Owens; A C Gallagher; T J Chambers
J Immunol (1996) 157 (2): 936–940.
View articletitled, IL-10 modulates formation of osteoclasts in murine hemopoietic cultures.
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A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse.
A J Rajan; Y L Gao; C S Raine; C F Brosnan
J Immunol (1996) 157 (2): 941–949.
View articletitled, A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse.
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Human IgG production in vivo: determination of synthetic rate by nonradioactive tracer incorporation.
C A Thornton; S Welle; R C Griggs; G N Abraham
J Immunol (1996) 157 (2): 950–955.
View articletitled, Human IgG production in vivo: determination of synthetic rate by nonradioactive tracer incorporation.
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Human IgG monoclonal antibodies that modulate the binding of specific IgE to birch pollen Bet v 1.
V Visco; C Dolecek; S Denépoux; J Le Mao; C Guret; F Rousset; M T Guinnepain; D Kraft; R Valenta; A Weyer; J Banchereau; S Labecque
J Immunol (1996) 157 (2): 956–962.
View articletitled, Human IgG monoclonal antibodies that modulate the binding of specific IgE to birch pollen Bet v 1.
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