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Volume 157, Issue 4
15 August 1996
Issue Cover
ISSN 0022-1767
EISSN 1550-6606
In this Issue

CUTTING EDGE

Beta-chemokine inhibition of monocytotropic HIV-1 infection. Interference with a postbinding fusion step.
T Oravecz; M Pall; M A Norcross
J Immunol (1996) 157 (4): 1329–1332.
View articletitled, Beta-chemokine inhibition of monocytotropic HIV-1 infection. Interference with a postbinding fusion step.
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CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis.
P J Perrin; J H Maldonado; T A Davis; C H June; M K Racke
J Immunol (1996) 157 (4): 1333–1336.
View articletitled, CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis.
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Direct measurement of anergy of antigen-specific T cells following oral tolerance induction.
N Van Houten; S F Blake
J Immunol (1996) 157 (4): 1337–1341.
View articletitled, Direct measurement of anergy of antigen-specific T cells following oral tolerance induction.
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ARTICLES

Naive murine neonatal T cells undergo apoptosis in response to primary stimulation.
B Adkins; K Chun; K Hamilton; M Nassiri
J Immunol (1996) 157 (4): 1343–1349.
View articletitled, Naive murine neonatal T cells undergo apoptosis in response to primary stimulation.
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A direct role for IFN-gamma in regulation of Th1 cell development.
L M Bradley; D K Dalton; M Croft
J Immunol (1996) 157 (4): 1350–1358.
View articletitled, A direct role for IFN-gamma in regulation of Th1 cell development.
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Bcl-2 expression inhibits prostaglandin E2-mediated apoptosis in B cell lymphomas.
D M Brown; R P Phipps
J Immunol (1996) 157 (4): 1359–1370.
View articletitled, Bcl-2 expression inhibits prostaglandin E2-mediated apoptosis in B cell lymphomas.
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Murine T lymphocytes modulate activity of an ATP-activated P2Z-type purinoceptor during differentiation.
T M Chused; S Apasov; M Sitkovsky
J Immunol (1996) 157 (4): 1371–1380.
View articletitled, Murine T lymphocytes modulate activity of an ATP-activated P2Z-type purinoceptor during differentiation.
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Coordinated regulation in human T cells of nucleotide-hydrolyzing ecto-enzymatic activities, including CD38 and PC-1. Possible role in the recycling of nicotinamide adenine dinucleotide metabolites.
P Deterre; L Gelman; H Gary-Gouy; C Arrieumerlou; V Berthelier; J M Tixier; S Ktorza; J Goding; C Schmitt; G Bismuth
J Immunol (1996) 157 (4): 1381–1388.
View articletitled, Coordinated regulation in human T cells of nucleotide-hydrolyzing ecto-enzymatic activities, including CD38 and PC-1. Possible role in the recycling of nicotinamide adenine dinucleotide metabolites.
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Activated B cells express CD28/B7-independent costimulatory activity.
L Ding; E M Shevach
J Immunol (1996) 157 (4): 1389–1396.
View articletitled, Activated B cells express CD28/B7-independent costimulatory activity.
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Reciprocal regulation of mucosal surface IgA+ B cells by Ig receptor cross-linking and CD40 ligand.
R O Ehrhardt; B Gray; R Duchmann; J K Inman; W Strober
J Immunol (1996) 157 (4): 1397–1405.
View articletitled, Reciprocal regulation of mucosal surface IgA+ B cells by Ig receptor cross-linking and CD40 ligand.
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Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion.
F D Finkelman; A Lees; R Birnbaum; W C Gause; S C Morris
J Immunol (1996) 157 (4): 1406–1414.
View articletitled, Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion.
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Inhibition of transcription factor Stat1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway.
L B Ivashkiv; E M Schmitt; A Castro
J Immunol (1996) 157 (4): 1415–1421.
View articletitled, Inhibition of transcription factor Stat1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway.
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Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen.
K Kuroda; J Yagi; K Imanishi; X J Yan; X Y Li; W Fujimaki; H Kato; T Miyoshi-Akiyama; Y Kumazawa; H Abe; T Uchiyama
J Immunol (1996) 157 (4): 1422–1431.
View articletitled, Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen.
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Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.
G Lack; K L Bradley; E Hamelmann; H Renz; J Loader; D Y Leung; G Larsen; E W Gelfand
J Immunol (1996) 157 (4): 1432–1439.
View articletitled, Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.
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CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.
Y Y Li; M Baccam; S B Waters; J E Pessin; G A Bishop; G A Koretzky
J Immunol (1996) 157 (4): 1440–1447.
View articletitled, CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.
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Expression of the CTL-associated protein TIA-1 during murine embryogenesis.
B Lowin; L French; J C Martinou; J Tschopp
J Immunol (1996) 157 (4): 1448–1454.
View articletitled, Expression of the CTL-associated protein TIA-1 during murine embryogenesis.
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Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression.
F E Lund; N Yu; K M Kim; M Reth; M C Howard
J Immunol (1996) 157 (4): 1455–1467.
View articletitled, Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression.
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Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells.
R Marhaba; F Mary; C Pelassy; A T Stanescu; C Aussel; J P Breittmayer
J Immunol (1996) 157 (4): 1468–1473.
View articletitled, Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells.
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B cells selected for apoptosis in the sheep ileal Peyer's patch have enhanced mutational diversity in the Ig V lambda light chain.
T A Maybaum; J D Reynolds
J Immunol (1996) 157 (4): 1474–1484.
View articletitled, B cells selected for apoptosis in the sheep ileal Peyer's patch have enhanced mutational diversity in the Ig V lambda light chain.
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Physical and functional association of Fc mu receptor on human natural killer cells with the zeta- and Fc epsilon RI gamma-chains and with src family protein tyrosine kinases.
H Rabinowich; M Manciulea; D Metes; A Sulica; R B Herberman; S J Corey; T L Whiteside
J Immunol (1996) 157 (4): 1485–1491.
View articletitled, Physical and functional association of Fc mu receptor on human natural killer cells with the zeta- and Fc epsilon RI gamma-chains and with src family protein tyrosine kinases.
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Somatic mutations in human Ig variable genes correlate with a partially functional CD40-ligand in the X-linked hyper-IgM syndrome.
D Razanajaona; C van Kooten; S Lebecque; J M Bridon; S Ho; S Smith; R Callard; J Banchereau; F Brière
J Immunol (1996) 157 (4): 1492–1498.
View articletitled, Somatic mutations in human Ig variable genes correlate with a partially functional CD40-ligand in the X-linked hyper-IgM syndrome.
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TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors.
H Strobl; E Riedl; C Scheinecker; C Bello-Fernandez; W F Pickl; K Rappersberger; O Majdic; W Knapp
J Immunol (1996) 157 (4): 1499–1507.
View articletitled, TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors.
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Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells.
Y Takahama; H Nakauchi
J Immunol (1996) 157 (4): 1508–1513.
View articletitled, Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells.
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Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-Jun N-terminal kinase.
A Tamir; Y Granot; N Isakov
J Immunol (1996) 157 (4): 1514–1522.
View articletitled, Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-Jun N-terminal kinase.
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Enhanced generation of NK cells with intact cytotoxic function in CD45 exon 6-deficient mice.
H Yamada; K Kishihara; Y Y Kong; K Nomoto
J Immunol (1996) 157 (4): 1523–1528.
View articletitled, Enhanced generation of NK cells with intact cytotoxic function in CD45 exon 6-deficient mice.
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Cytokine-mediated communication between dendritic epidermal T cells and Langerhans cells. In vitro studies using cell lines.
K Yokota; K Ariizumi; T Kitajima; P R Bergstresser; N E Street; A Takashima
J Immunol (1996) 157 (4): 1529–1537.
View articletitled, Cytokine-mediated communication between dendritic epidermal T cells and Langerhans cells. In vitro studies using cell lines.
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The transcription factor B-cell-specific activator protein is not involved in the IL-4-induced activation of the human IgE germline promoter.
B Albrecht; S Peiritsch; B Messner; M Woisetschläger
J Immunol (1996) 157 (4): 1538–1543.
View articletitled, The transcription factor B-cell-specific activator protein is not involved in the IL-4-induced activation of the human IgE germline promoter.
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A third Ig light chain gene isotype in Xenopus laevis consists of six distinct VL families and is related to mammalian lambda genes.
R N Haire; T Ota; J P Rast; R T Litman; F Y Chan; L I Zon; G W Litman
J Immunol (1996) 157 (4): 1544–1550.
View articletitled, A third Ig light chain gene isotype in Xenopus laevis consists of six distinct VL families and is related to mammalian lambda genes.
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The rat MHC haplotype RT1c expresses two classical class I molecules.
E Joly; L Leong; W J Coadwell; C Clarkson; G W Butcher
J Immunol (1996) 157 (4): 1551–1558.
View articletitled, The rat MHC haplotype RT1c expresses two classical class I molecules.
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Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes.
Y J Lee; E N Benveniste
J Immunol (1996) 157 (4): 1559–1568.
View articletitled, Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes.
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Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains.
M Okumura; R J Matthews; B Robb; G W Litman; P Bork; M L Thomas
J Immunol (1996) 157 (4): 1569–1575.
View articletitled, Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains.
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The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding.
A Tamm; R E Schmidt
J Immunol (1996) 157 (4): 1576–1581.
View articletitled, The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding.
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Characterization of an Ig VH idiotope that results in specific homophilic binding and increased avidity for antigen.
X Yan; S V Evans; M J Kaminki; S D Gillies; R A Reisfeld; A N Houghton; P B Chapman
J Immunol (1996) 157 (4): 1582–1588.
View articletitled, Characterization of an Ig VH idiotope that results in specific homophilic binding and increased avidity for antigen.
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IL-12 is both required and sufficient for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells.
R Bianchi; U Grohmann; M L Belladonna; S Silla; F Fallarino; E Ayroldi; M C Fioretti; P Puccetti
J Immunol (1996) 157 (4): 1589–1597.
View articletitled, IL-12 is both required and sufficient for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells.
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Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.
J O Brubaker; C M Thompson; L A Morrison; D M Knipe; G R Siber; R W Finberg
J Immunol (1996) 157 (4): 1598–1604.
View articletitled, Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.
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Rhinovirus produces nonspecific activation of lymphocytes through a monocyte-dependent mechanism.
J E Gern; R Vrtis; E A Kelly; E C Dick; W W Busse
J Immunol (1996) 157 (4): 1605–1612.
View articletitled, Rhinovirus produces nonspecific activation of lymphocytes through a monocyte-dependent mechanism.
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Escherichia coli and Pseudomonas aeruginosa induce expansion of V delta 2 cells in adult peripheral blood, but of V delta 1 cells in cord blood.
C M Kersten; R T McCluskey; L A Boyle; J T Kurnick
J Immunol (1996) 157 (4): 1613–1619.
View articletitled, Escherichia coli and Pseudomonas aeruginosa induce expansion of V delta 2 cells in adult peripheral blood, but of V delta 1 cells in cord blood.
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Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria.
D M Yañez; D D Manning; A J Cooley; W P Weidanz; H C van der Heyde
J Immunol (1996) 157 (4): 1620–1624.
View articletitled, Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria.
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Enhancement of TNF-alpha synthesis by overexpression of G alpha z in a mast cell line.
R A Baumgartner; N Hirasawa; K Ozawa; F Gusovsky; M A Beaven
J Immunol (1996) 157 (4): 1625–1629.
View articletitled, Enhancement of TNF-alpha synthesis by overexpression of G alpha z in a mast cell line.
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In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.
T S Blackwell; T R Blackwell; E P Holden; B W Christman; J W Christman
J Immunol (1996) 157 (4): 1630–1637.
View articletitled, In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.
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Stress-induced changes in blood leukocyte distribution. Role of adrenal steroid hormones.
F S Dhabhar; A H Miller; B S McEwen; R L Spencer
J Immunol (1996) 157 (4): 1638–1644.
View articletitled, Stress-induced changes in blood leukocyte distribution. Role of adrenal steroid hormones.
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Anaphylaxis mediated through a humanized high affinity IgE receptor.
D Dombrowicz; A T Brini; V Flamand; E Hicks; J N Snouwaert; J P Kinet; B H Koller
J Immunol (1996) 157 (4): 1645–1651.
View articletitled, Anaphylaxis mediated through a humanized high affinity IgE receptor.
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Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.
J A Francisco; P A Kiener; P Moran-Davis; J A Ledbetter; C B Siegall
J Immunol (1996) 157 (4): 1652–1658.
View articletitled, Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.
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Analysis of the gene that encodes the complement regulatory protein, membrane inhibitor of reactive lysis (CD59). Identification of an alternatively spliced exon and characterization of the transcriptional regulatory regions of the promoter.
M H Holguin; C B Martin; T Eggett; C J Parker
J Immunol (1996) 157 (4): 1659–1668.
View articletitled, Analysis of the gene that encodes the complement regulatory protein, membrane inhibitor of reactive lysis (CD59). Identification of an alternatively spliced exon and characterization of the transcriptional regulatory regions of the promoter.
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Phospholipase A2 triggers the first phase of the thermal stress response and exhibits cell-type specificity.
D A Jurivich; S Pangas; L Qiu; J F Welk
J Immunol (1996) 157 (4): 1669–1677.
View articletitled, Phospholipase A2 triggers the first phase of the thermal stress response and exhibits cell-type specificity.
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Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability.
W Luttmann; B Knoechel; M Foerster; H Matthys; J C Virchow, Jr; C Kroegel
J Immunol (1996) 157 (4): 1678–1683.
View articletitled, Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability.
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Priming of eosinophil recruitment in vivo by LPS pretreatment.
D M Macari; M M Teixeira; P G Hellewell
J Immunol (1996) 157 (4): 1684–1692.
View articletitled, Priming of eosinophil recruitment in vivo by LPS pretreatment.
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C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway.
G Nilsson; M Johnell; C H Hammer; H L Tiffany; K Nilsson; D D Metcalfe; A Siegbahn; P M Murphy
J Immunol (1996) 157 (4): 1693–1698.
View articletitled, C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway.
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IL-1 beta activation in human epidermis.
E Nylander-Lundqvist; O Bäck; T Egelrud
J Immunol (1996) 157 (4): 1699–1704.
View articletitled, IL-1 beta activation in human epidermis.
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IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury.
C A Redlich; X Gao; S Rockwell; M Kelley; J A Elias
J Immunol (1996) 157 (4): 1705–1710.
View articletitled, IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury.
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Functional and structural characterization of the eosinophil P-selectin ligand.
F A Symon; M B Lawrence; M L Williamson; G M Walsh; S R Watson; A J Wardlaw
J Immunol (1996) 157 (4): 1711–1719.
View articletitled, Functional and structural characterization of the eosinophil P-selectin ligand.
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Mouse bone marrow-derived mast cells and mast cell lines constitutively produce B cell growth and differentiation activities.
C Tkaczyk; P Frandji; H G Botros; P Poncet; J Lapeyre; R Peronet; B David; S Mécheri
J Immunol (1996) 157 (4): 1720–1728.
View articletitled, Mouse bone marrow-derived mast cells and mast cell lines constitutively produce B cell growth and differentiation activities.
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CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin.
T Werfel; J Zwirner; M Oppermann; A Sieber; G Begemann; W Drommer; A Kapp; O Götze
J Immunol (1996) 157 (4): 1729–1735.
View articletitled, CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin.
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Identification of mouse granulocyte chemotactic protein-2 from fibroblasts and epithelial cells. Functional comparison with natural KC and macrophage inflammatory protein-2.
A Wuyts; A Haelens; P Proost; J P Lenaerts; R Conings; G Opdenakker; J Van Damme
J Immunol (1996) 157 (4): 1736–1743.
View articletitled, Identification of mouse granulocyte chemotactic protein-2 from fibroblasts and epithelial cells. Functional comparison with natural KC and macrophage inflammatory protein-2.
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Role of vitamin D3-binding protein in activation of mouse macrophages.
N Yamamoto; V R Naraparaju
J Immunol (1996) 157 (4): 1744–1749.
View articletitled, Role of vitamin D3-binding protein in activation of mouse macrophages.
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Induction of autoimmunity in the absence of CD28 costimulation.
K Bachmaier; C Pummerer; A Shahinian; J Ionescu; N Neu; T W Mak; J M Penninger
J Immunol (1996) 157 (4): 1752–1757.
View articletitled, Induction of autoimmunity in the absence of CD28 costimulation.
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Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha.
C K Edwards, 3rd; T Zhou; J Zhang; T J Baker; M De; R E Long; D R Borcherding; T L Bowlin; H Bluethmann; J D Mountz
J Immunol (1996) 157 (4): 1758–1772.
View articletitled, Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha.
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Biochemical characterization and microsequencing of a 205-kDa synovial protein stimulatory for T cells and reactive with rheumatoid factor containing sera.
N A Hain; B Stuhlmüller; G R Hahn; J R Kalden; R Deutzmann; G R Burmester
J Immunol (1996) 157 (4): 1773–1780.
View articletitled, Biochemical characterization and microsequencing of a 205-kDa synovial protein stimulatory for T cells and reactive with rheumatoid factor containing sera.
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T-T cellular interaction between CD4-CD8- regulatory T cells and T cell clones presenting TCR peptide. Its implication for TCR vaccination against experimental autoimmune encephalomyelitis.
M F Kozovska; T Yamamura; T Tabira
J Immunol (1996) 157 (4): 1781–1790.
View articletitled, T-T cellular interaction between CD4-CD8- regulatory T cells and T cell clones presenting TCR peptide. Its implication for TCR vaccination against experimental autoimmune encephalomyelitis.
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Susceptibility of HIV-1 plasma virus to complement-mediated lysis. Evidence for a role in clearance of virus in vivo.
B L Sullivan; E J Knopoff; M Saifuddin; D M Takefman; M N Saarloos; B E Sha; G T Spear
J Immunol (1996) 157 (4): 1791–1798.
View articletitled, Susceptibility of HIV-1 plasma virus to complement-mediated lysis. Evidence for a role in clearance of virus in vivo.
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Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells.
E Suri-Payer; P J Kehn; A W Cheever; E M Shevach
J Immunol (1996) 157 (4): 1799–1805.
View articletitled, Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells.
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Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways.
L M Teran; N Noso; M Carroll; D E Davies; S Holgate; J M Schröder
J Immunol (1996) 157 (4): 1806–1812.
View articletitled, Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways.
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