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Volume 157, Issue 6
15 September 1996
Issue Cover
ISSN 0022-1767
EISSN 1550-6606
In this Issue

CUTTING EDGE

A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens.
C M Snapper; J J Mond
J Immunol (1996) 157 (6): 2229–2233.
View articletitled, A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens.
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Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP.
G W Chacko; S Tridandapani; J E Damen; L Liu; G Krystal; K M Coggeshall
J Immunol (1996) 157 (6): 2234–2238.
View articletitled, Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP.
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Regulation of CTL recognition by receptors for HLA-DR molecules.
H Nakajima; M Takiguchi
J Immunol (1996) 157 (6): 2239–2242.
View articletitled, Regulation of CTL recognition by receptors for HLA-DR molecules.
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Phosphatidylinositol 3 kinase activity is not essential for B7-1-mediated costimulation of proliferation or development of cytotoxicity in murine T cells.
H T Ni; M J Deeths; M F Mescher
J Immunol (1996) 157 (6): 2243–2246.
View articletitled, Phosphatidylinositol 3 kinase activity is not essential for B7-1-mediated costimulation of proliferation or development of cytotoxicity in murine T cells.
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ARTICLES

Effect of HLA-DM transfection on hen egg lysozyme presentation by T2.Ak cells.
L J Albert; B Ghumman; T H Watts
J Immunol (1996) 157 (6): 2247–2255.
View articletitled, Effect of HLA-DM transfection on hen egg lysozyme presentation by T2.Ak cells.
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The mechanisms of peptide exchange and beta 2-microglobulin exchange on cell surface Ld and Kb molecules are noncooperative.
J R Cook; N B Myers; T H Hansen
J Immunol (1996) 157 (6): 2256–2261.
View articletitled, The mechanisms of peptide exchange and beta 2-microglobulin exchange on cell surface Ld and Kb molecules are noncooperative.
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Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site.
R M Egan; C Yorkey; R Black; W K Loh; J L Stevens; J G Woodward
J Immunol (1996) 157 (6): 2262–2271.
View articletitled, Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site.
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Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2.
J Gómez; C Martínez-A; B Fernández; A García; A Rebollo
J Immunol (1996) 157 (6): 2272–2281.
View articletitled, Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2.
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Characterization of the human C6 promoter: requirement of the CCAAT enhancer binding protein binding site for C6 gene promoter activity.
S González; C López-Larrea
J Immunol (1996) 157 (6): 2282–2290.
View articletitled, Characterization of the human C6 promoter: requirement of the CCAAT enhancer binding protein binding site for C6 gene promoter activity.
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TCR recognition of the Hb(64-76)/I-Ek determinant: single conservative amino acid changes in the complementarity-determining region 3 dramatically alter antigen fine specificity.
B L Hsu; D L Donermeyer; P M Allen
J Immunol (1996) 157 (6): 2291–2298.
View articletitled, TCR recognition of the Hb(64-76)/I-Ek determinant: single conservative amino acid changes in the complementarity-determining region 3 dramatically alter antigen fine specificity.
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Delayed tyrosine phosphorylation and nuclear expression of STAT1 following antigen receptor stimulation of B lymphocytes.
J G Karras; L Huo; Z Wang; D A Frank; J M Zimmet; T L Rothstein
J Immunol (1996) 157 (6): 2299–2309.
View articletitled, Delayed tyrosine phosphorylation and nuclear expression of STAT1 following antigen receptor stimulation of B lymphocytes.
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Inhibition of TC-1 cytokine production, effector cytotoxic T lymphocyte development and alloantibody production by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
N I Kerkvliet; L Baecher-Steppan; D M Shepherd; J A Oughton; B A Vorderstrasse; G K DeKrey
J Immunol (1996) 157 (6): 2310–2319.
View articletitled, Inhibition of TC-1 cytokine production, effector cytotoxic T lymphocyte development and alloantibody production by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
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TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen.
R Khattri; A I Sperling; D Qian; F W Fitch; E W Shores; P E Love; J A Bluestone
J Immunol (1996) 157 (6): 2320–2327.
View articletitled, TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen.
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Multifactor cis-dominant negative regulation of IL-2 gene expression in anergized T cells.
S Kitagawa-Sakakida; R H Schwartz
J Immunol (1996) 157 (6): 2328–2339.
View articletitled, Multifactor cis-dominant negative regulation of IL-2 gene expression in anergized T cells.
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T cell-mediated terminal maturation of dendritic cells: loss of adhesive and phagocytotic capacities.
T Kitajima; G Caceres-Dittmar; F J Tapia; J Jester; P R Bergstresser; A Takashima
J Immunol (1996) 157 (6): 2340–2347.
View articletitled, T cell-mediated terminal maturation of dendritic cells: loss of adhesive and phagocytotic capacities.
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High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis.
T Marth; W Strober; B L Kelsall
J Immunol (1996) 157 (6): 2348–2357.
View articletitled, High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis.
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Selective activation of CD8 T cell effector functions by epitope variants of lymphocytic choriomeningitis virus glycoprotein.
S Martin; H Kohler; H U Weltzien; C Leipner
J Immunol (1996) 157 (6): 2358–2365.
View articletitled, Selective activation of CD8 T cell effector functions by epitope variants of lymphocytic choriomeningitis virus glycoprotein.
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Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice.
T A Moore; U von Freeden-Jeffry; R Murray; A Zlotnik
J Immunol (1996) 157 (6): 2366–2373.
View articletitled, Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice.
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Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells.
L G Rider; N Hirasawa; F Santini; M A Beaven
J Immunol (1996) 157 (6): 2374–2380.
View articletitled, Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells.
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Granzyme B induces apoptosis and cyclin A-associated cyclin-dependent kinase activity in all stages of the cell cycle.
L Shi; G Chen; D He; D G Bosc; D W Litchfield; A H Greenberg
J Immunol (1996) 157 (6): 2381–2385.
View articletitled, Granzyme B induces apoptosis and cyclin A-associated cyclin-dependent kinase activity in all stages of the cell cycle.
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Viral peptide specific induction of MHC class II expression by murine T cell clones.
D B Thomas; C A Smith; C M Graham
J Immunol (1996) 157 (6): 2386–2394.
View articletitled, Viral peptide specific induction of MHC class II expression by murine T cell clones.
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Role of reactive oxygen intermediates in TCR-induced death of T cell blasts and hybridomas.
M S Williams; P A Henkart
J Immunol (1996) 157 (6): 2395–2402.
View articletitled, Role of reactive oxygen intermediates in TCR-induced death of T cell blasts and hybridomas.
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MHC class I-processed pseudogenes in New World primates provide evidence for rapid turnover of MHC class I genes.
L F Cadavid; A L Hughes; D I Watkins
J Immunol (1996) 157 (6): 2403–2409.
View articletitled, MHC class I-processed pseudogenes in New World primates provide evidence for rapid turnover of MHC class I genes.
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Differential activation of the nuclear factor-kappa B by TNF muteins specific for the p60 and p80 TNF receptors.
G B Chainy; S Singh; U Raju; B B Aggarwal
J Immunol (1996) 157 (6): 2410–2417.
View articletitled, Differential activation of the nuclear factor-kappa B by TNF muteins specific for the p60 and p80 TNF receptors.
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Characterization of three promoter elements and cognate DNA binding protein(s) necessary for IFN-gamma induction of gp91-phox transcription.
E A Eklund; W Luo; D G Skalnik
J Immunol (1996) 157 (6): 2418–2429.
View articletitled, Characterization of three promoter elements and cognate DNA binding protein(s) necessary for IFN-gamma induction of gp91-phox transcription.
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Correlation between the amino acid position of arginine in VH-CDR3 and specificity for native DNA among autoimmune antibodies.
M R Krishnan; N T Jou; T N Marion
J Immunol (1996) 157 (6): 2430–2439.
View articletitled, Correlation between the amino acid position of arginine in VH-CDR3 and specificity for native DNA among autoimmune antibodies.
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The B cell response to autologous type II collagen: biased V gene repertoire with V gene sharing and epitope shift.
J A Mo; R Holmdahl
J Immunol (1996) 157 (6): 2440–2448.
View articletitled, The B cell response to autologous type II collagen: biased V gene repertoire with V gene sharing and epitope shift.
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Use of phage surface expression to analyze regions of human V4-34(VH4-21)-encoded IgG autoantibody required for recognition of DNA: no involvement of the 9G4 idiotope.
C I Mockridge; C J Chapman; M B Spellerberg; D A Isenberg; F K Stevenson
J Immunol (1996) 157 (6): 2449–2454.
View articletitled, Use of phage surface expression to analyze regions of human V4-34(VH4-21)-encoded IgG autoantibody required for recognition of DNA: no involvement of the 9G4 idiotope.
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Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles.
G Noun; M Reboul; J P Abastado; C Jaulin; P Kourilsky; M Pla
J Immunol (1996) 157 (6): 2455–2461.
View articletitled, Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles.
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HOXB cluster genes in activated natural killer lymphocytes: expression from 3'-->5' cluster side and proliferative function.
M T Quaranta; M Petrini; E Tritarelli; P Samoggia; A Carè; L Bottero; U Testa; C Peschle
J Immunol (1996) 157 (6): 2462–2469.
View articletitled, HOXB cluster genes in activated natural killer lymphocytes: expression from 3'-->5' cluster side and proliferative function.
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Probing HLA-B7 conformational shifts induced by peptide-binding groove mutations and bound peptide with anti-HLA monoclonal antibodies.
K D Smith; B E Mace; A Valenzuela; J L Vigna; J A McCutcheon; J A Barbosa; E Huczko; V H Engelhard; C T Lutz
J Immunol (1996) 157 (6): 2470–2478.
View articletitled, Probing HLA-B7 conformational shifts induced by peptide-binding groove mutations and bound peptide with anti-HLA monoclonal antibodies.
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Species-dependent post-translational modification and position 2 allelism: effects on streptococcal superantigen SSA structure and V beta specificity.
K R Stevens; M Van; J G Lamphear; R S Orkiszewski; K D Ballard; R G Cook; R R Rich
J Immunol (1996) 157 (6): 2479–2487.
View articletitled, Species-dependent post-translational modification and position 2 allelism: effects on streptococcal superantigen SSA structure and V beta specificity.
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Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif.
J L Viney; S Jones; H H Chiu; B Lagrimas; M E Renz; L G Presta; D Jackson; K J Hillan; S Lew; S Fong
J Immunol (1996) 157 (6): 2488–2497.
View articletitled, Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif.
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Interval mapping of quantitative trait loci controlling humoral immunity to exogenous antigens: evidence that non-MHC immune response genes may also influence susceptibility to autoimmunity.
J Wu; J A Longmate; G Adamus; P A Hargrave; E K Wakeland
J Immunol (1996) 157 (6): 2498–2505.
View articletitled, Interval mapping of quantitative trait loci controlling humoral immunity to exogenous antigens: evidence that non-MHC immune response genes may also influence susceptibility to autoimmunity.
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Respiratory syncytial virus infection of human respiratory epithelial cells up-regulates class I MHC expression through the induction of IFN-beta and IL-1 alpha.
R Garofalo; F Mei; R Espejo; G Ye; H Haeberle; S Baron; P L Ogra; V E Reyes
J Immunol (1996) 157 (6): 2506–2513.
View articletitled, Respiratory syncytial virus infection of human respiratory epithelial cells up-regulates class I MHC expression through the induction of IFN-beta and IL-1 alpha.
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Bacteria in the bloodstream are trapped in the liver and killed by immigrating neutrophils.
S H Gregory; A J Sagnimeni; E J Wing
J Immunol (1996) 157 (6): 2514–2520.
View articletitled, Bacteria in the bloodstream are trapped in the liver and killed by immigrating neutrophils.
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Mucosal or targeted lymph node immunization of macaques with a particulate SIVp27 protein elicits virus-specific CTL in the genito-rectal mucosa and draining lymph nodes.
L S Klavinskis; L A Bergmeier; L Gao; E Mitchell; R G Ward; G Layton; R Brookes; N J Meyers; T Lehner
J Immunol (1996) 157 (6): 2521–2527.
View articletitled, Mucosal or targeted lymph node immunization of macaques with a particulate SIVp27 protein elicits virus-specific CTL in the genito-rectal mucosa and draining lymph nodes.
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IL-10 enhances the growth of Legionella pneumophila in human mononuclear phagocytes and reverses the protective effect of IFN-gamma: differential responses of blood monocytes and alveolar macrophages.
D R Park; S J Skerrett
J Immunol (1996) 157 (6): 2528–2538.
View articletitled, IL-10 enhances the growth of Legionella pneumophila in human mononuclear phagocytes and reverses the protective effect of IFN-gamma: differential responses of blood monocytes and alveolar macrophages.
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Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.
M R Parkhurst; M L Salgaller; S Southwood; P F Robbins; A Sette; S A Rosenberg; Y Kawakami
J Immunol (1996) 157 (6): 2539–2548.
View articletitled, Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.
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Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system.
R Savedra, Jr; R L Delude; R R Ingalls; M J Fenton; D T Golenbock
J Immunol (1996) 157 (6): 2549–2554.
View articletitled, Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system.
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L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits.
S R Sharar; N N Chapman; L C Flaherty; J M Harlan; T F Tedder; R K Winn
J Immunol (1996) 157 (6): 2555–2563.
View articletitled, L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits.
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IL-4 is protective against development of toxoplasmic encephalitis.
Y Suzuki; Q Yang; S Yang; N Nguyen; S Lim; O Liesenfeld; T Kojima; J S Remington
J Immunol (1996) 157 (6): 2564–2569.
View articletitled, IL-4 is protective against development of toxoplasmic encephalitis.
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I-309/T cell activation gene-3 chemokine protects murine T cell lymphomas against dexamethasone-induced apoptosis.
J Van Snick; F Houssiau; P Proost; J Van Damme; J C Renauld
J Immunol (1996) 157 (6): 2570–2576.
View articletitled, I-309/T cell activation gene-3 chemokine protects murine T cell lymphomas against dexamethasone-induced apoptosis.
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In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes.
G J Bellingan; H Caldwell; S E Howie; I Dransfield; C Haslett
J Immunol (1996) 157 (6): 2577–2585.
View articletitled, In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes.
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The baboon erythrocyte complement receptor is a glycophosphatidylinositol-linked protein encoded by a homologue of the human CR1-like genetic element.
D J Birmingham; C M Logar; X P Shen; W Chen
J Immunol (1996) 157 (6): 2586–2592.
View articletitled, The baboon erythrocyte complement receptor is a glycophosphatidylinositol-linked protein encoded by a homologue of the human CR1-like genetic element.
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p161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N.
H Chen; C A Kinzer; W E Paul
J Immunol (1996) 157 (6): 2593–2600.
View articletitled, p161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N.
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Complement C4 protein expression by rat hepatic stellate cells.
C J Fimmel; K E Brown; R O'Neill; R D Kladney
J Immunol (1996) 157 (6): 2601–2609.
View articletitled, Complement C4 protein expression by rat hepatic stellate cells.
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IFN-gamma inhibits thrombin- and endotoxin-induced plasminogen activator inhibitor type 1 in human endothelial cells.
M Gallicchio; P Hufnagl; J Wojta; P Tipping
J Immunol (1996) 157 (6): 2610–2617.
View articletitled, IFN-gamma inhibits thrombin- and endotoxin-induced plasminogen activator inhibitor type 1 in human endothelial cells.
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IL-6 is an in vitro and in vivo autocrine growth factor for middle T antigen-transformed endothelial cells.
E Giraudo; M Arese; C Toniatti; M Strasly; L Primo; A Mantovani; G Ciliberto; F Bussolini
J Immunol (1996) 157 (6): 2618–2623.
View articletitled, IL-6 is an in vitro and in vivo autocrine growth factor for middle T antigen-transformed endothelial cells.
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Quantum proteolysis resulting from release of single granules by human neutrophils: a novel, nonoxidative mechanism of extracellular proteolytic activity.
T G Liou; E J Campbell
J Immunol (1996) 157 (6): 2624–2631.
View articletitled, Quantum proteolysis resulting from release of single granules by human neutrophils: a novel, nonoxidative mechanism of extracellular proteolytic activity.
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Monocyte IL-8 release is induced by two independent Fc gamma R- mediated pathways.
C B Marsh; C L Anderson; M P Lowe; M D Wewers
J Immunol (1996) 157 (6): 2632–2637.
View articletitled, Monocyte IL-8 release is induced by two independent Fc gamma R- mediated pathways.
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Regulation of inducible nitric oxide synthase expression in IFN-gamma-treated murine macrophages cultured under hypoxic conditions.
G Melillo; L S Taylor; A Brooks; G W Cox; L Varesio
J Immunol (1996) 157 (6): 2638–2644.
View articletitled, Regulation of inducible nitric oxide synthase expression in IFN-gamma-treated murine macrophages cultured under hypoxic conditions.
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Induction of the TNF-alpha promoter in the murine dendritic cell line 18 and the murine mast cell line CPII is differently regulated.
E E Preischl; G G Pendl; A Elbe; E Serfling; N E Harrer; G Stingl; T Baumruker
J Immunol (1996) 157 (6): 2645–2653.
View articletitled, Induction of the TNF-alpha promoter in the murine dendritic cell line 18 and the murine mast cell line CPII is differently regulated.
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A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity.
J D Spahn; S J Szefler; W Surs; D E Doherty; S R Nimmagadda; D Y Leung
J Immunol (1996) 157 (6): 2654–2659.
View articletitled, A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity.
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T helper 2 cytokines differently regulate monocyte chemoattractant protein-1 production by human peripheral blood monocytes and alveolar macrophages.
S Yano; H Yanagawa; Y Nishioka; N Mukaida; K Matsushima; S Sone
J Immunol (1996) 157 (6): 2660–2665.
View articletitled, T helper 2 cytokines differently regulate monocyte chemoattractant protein-1 production by human peripheral blood monocytes and alveolar macrophages.
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Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response.
R R Caspi; P B Silver; C C Chan; B Sun; R K Agarwal; J Wells; S Oddo; Y Fujino; F Najafian; R L Wilder
J Immunol (1996) 157 (6): 2668–2675.
View articletitled, Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response.
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The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand black (NZB) mice.
S Y Chen; Y Takeoka; A A Ansari; R Boyd; D M Klinman; M E Gershwin
J Immunol (1996) 157 (6): 2676–2684.
View articletitled, The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand black (NZB) mice.
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Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs.
C Q Chu; M Londei
J Immunol (1996) 157 (6): 2685–2689.
View articletitled, Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs.
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Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes: II. Abnormal isozyme kinetics.
G M Kammer; I U Khan; J A Kammer; I Olorenshaw; D Mathis
J Immunol (1996) 157 (6): 2690–2698.
View articletitled, Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes: II. Abnormal isozyme kinetics.
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Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome.
A Kurdowska; E J Miller; J M Noble; R P Baughman; M A Matthay; W G Brelsford; A B Cohen
J Immunol (1996) 157 (6): 2699–2706.
View articletitled, Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome.
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Autoantibodies in insulin-dependent diabetes recognize distinct cytoplasmic domains of the protein tyrosine phosphatase-like IA-2 autoantigen.
V Lampasona; M Bearzatto; S Genovese; E Bosi; M Ferrari; E Bonifacio
J Immunol (1996) 157 (6): 2707–2711.
View articletitled, Autoantibodies in insulin-dependent diabetes recognize distinct cytoplasmic domains of the protein tyrosine phosphatase-like IA-2 autoantigen.
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Single cell analysis of IL-4 and IFN-gamma production by T cells from HIV-infected individuals: decreased IFN-gamma in the presence of preserved IL-4 production.
L Meyaard; E Hovenkamp; I P Keet; B Hooibrink; I H de Jong; S A Otto; F Miedema
J Immunol (1996) 157 (6): 2712–2718.
View articletitled, Single cell analysis of IL-4 and IFN-gamma production by T cells from HIV-infected individuals: decreased IFN-gamma in the presence of preserved IL-4 production.
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Backcross analysis of genes linked to autoantibody production in New Zealand White mice.
T J Vyse; L Morel; F J Tanner; E K Wakeland; B L Kotzin
J Immunol (1996) 157 (6): 2719–2727.
View articletitled, Backcross analysis of genes linked to autoantibody production in New Zealand White mice.
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Disturbed myeloperoxidase-dependent activity of neutrophils in cystic fibrosis homozygotes and heterozygotes, and its correction by amiloride.
V Witko-Sarsat; R C Allen; M Paulais; A T Nguyen; G Bessou; G Lenoir; B Descamps-Latscha
J Immunol (1996) 157 (6): 2728–2735.
View articletitled, Disturbed myeloperoxidase-dependent activity of neutrophils in cystic fibrosis homozygotes and heterozygotes, and its correction by amiloride.
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LETTERS TO THE EDITOR

The expression by dendritic cells of a new C-C or beta family chemokine.
A Zlotnik
J Immunol (1996) 157 (6): 2736.
View articletitled, The expression by dendritic cells of a new C-C or beta family chemokine.
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