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Volume 159, Issue 1
1 July 1997
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ISSN 0022-1767
EISSN 1550-6606
In this Issue

EDITORIALS

The Journal of Immunology is Dead! Long Live the Journal of Immunology!
FW Fitch,
J Immunol (1997) 159 (1): 1.
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CUTTING EDGE

Testosterone therapy ameliorates experimental autoimmune encephalomyelitis and induces a T helper 2 bias in the autoantigen-specific T lymphocyte response.
M Dalal; S Kim; R R Voskuhl
J Immunol (1997) 159 (1): 3–6.
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IL-4 secretion by CD4+ NK1+ T cells induces monocyte chemoattractant protein-1 in early listeriosis.
I E Flesch; A Wandersee; S H Kaufmann
J Immunol (1997) 159 (1): 7–10.
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The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites.
A Iwasaki; C A Torres; P S Ohashi; H L Robinson; B H Barber
J Immunol (1997) 159 (1): 11–14.
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ARTICLES

Ca2+-dependent, Fas- and perforin-independent apoptotic death of allografted tumor cells by a type of activated macrophage.
R Yoshida; A Sanchez-Bueno; N Yamamoto; K Einaga-Naito
J Immunol (1997) 159 (1): 15–21.
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The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms.
R T Elder; X Xu; J W Williams; H Gong; A Finnegan; A S Chong
J Immunol (1997) 159 (1): 22–27.
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IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells.
P Kaliński; C M Hilkens; A Snijders; F G Snijdewint; M L Kapsenberg
J Immunol (1997) 159 (1): 28–35.
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Differential expression of transcription directed by a discrete NF-AT binding element from the IL-4 promoter in naive and effector CD4 T cells.
T M Aune; R A Flavell
J Immunol (1997) 159 (1): 36–43.
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Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora.
S L Brandwein; R P McCabe; Y Cong; K B Waites; B U Ridwan; P A Dean; T Ohkusa; E H Birkenmeier; J P Sundberg; C O Elson
J Immunol (1997) 159 (1): 44–52.
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Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.
A Faith; C A Akdis; M Akdis; H U Simon; K Blaser
J Immunol (1997) 159 (1): 53–60.
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Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide:MHC molecules.
J E Lee; M B Cossoy; L A Chau; B Singh; J Madrenas
J Immunol (1997) 159 (1): 61–69.
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Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells.
L E Marengère; C Mirtsos; I Kozieradzki; A Veillette; T W Mak; J M Penninger
J Immunol (1997) 159 (1): 70–76.
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Immunodominant CD4+ T cell receptor Vbeta repertoires involved in graft-versus-host disease responses to minor histocompatibility antigens.
M A Berger; R Korngold
J Immunol (1997) 159 (1): 77–85.
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Selective expansion of Vgamma2-Vdelta7 TCR gammadelta cells in C57BL/6 mice is postnatal and extrathymic.
A I Sperling; D C Decker; R J DiPaolo; D A Stern; A Shum; J A Bluestone
J Immunol (1997) 159 (1): 86–91.
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Regulation of tumor antigen presentation by urocanic acid.
S Beissert; T Mohammad; H Torri; A Lonati; Z Yan; H Morrison; R D Granstein
J Immunol (1997) 159 (1): 92–96.
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Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type I T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells.
K Matsui; T Yoshimoto; H Tsutsui; Y Hyodo; N Hayashi; K Hiroishi; N Kawada; H Okamura; K Nakanishi; K Higashino
J Immunol (1997) 159 (1): 97–106.
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Inhibition of primary and recall allergen-specific T helper cell type 2-mediated responses by a T helper cell type 1 stimulus.
D E Scott; I Agranovich; J Inman; M Gober; B Golding
J Immunol (1997) 159 (1): 107–116.
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TGF-beta down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors.
J Tang; B L Nuccie; I Ritterman; J L Liesveld; C N Abboud; D H Ryan
J Immunol (1997) 159 (1): 117–125.
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Bcl-2 expression in target cells leads to functional inhibition of caspase-3 protease family in human NK and lymphokine-activated killer cell granule-mediated apoptosis.
C Renvoizé; R Roger; N Moulian; J Bertoglio; J Bréard
J Immunol (1997) 159 (1): 126–134.
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xid affects events leading to B cell cycle entry.
K Brorson; M Brunswick; S Ezhevsky; D G Wei; R Berg; D Scott; K E Stein
J Immunol (1997) 159 (1): 135–143.
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Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.
E Chuang; M L Alegre; C S Duckett; P J Noel; M G Vander Heiden; C B Thompson
J Immunol (1997) 159 (1): 144–151.
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Direct MHC class I complementary DNA transfer to thymus induces donor-specific unresponsiveness, which involves multiple immunologic mechanisms.
S J Knechtle; J Wang; C Graeb; Y Zhai; X Hong; J H Fechner, Jr; E K Geissler
J Immunol (1997) 159 (1): 152–158.
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Requirement of CD4 T cells for skin graft rejection against thymus leukemia (TL) antigen and multiple epitopes on the TL molecule recognized by CD4 T cells.
K Tsuji; Y Obata; T Takahashi; J Arata; E Nakayama
J Immunol (1997) 159 (1): 159–166.
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In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice.
X Xu; L Blinder; J Shen; H Gong; A Finnegan; J W Williams; A S Chong
J Immunol (1997) 159 (1): 167–174.
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TGF-beta inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes.
J J Bright; L D Kerr; S Sriram
J Immunol (1997) 159 (1): 175–183.
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CD38 ligation in human B cell progenitors triggers tyrosine phosphorylation of CD19 and association of CD19 with lyn and phosphatidylinositol 3-kinase.
A Kitanaka; C Ito; E Coustan-Smith; D Campana
J Immunol (1997) 159 (1): 184–192.
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CD38 ligation results in activation of the Raf-1/mitogen-activated protein kinase and the CD3-zeta/zeta-associated protein-70 signaling pathways in Jurkat T lymphocytes.
M Zubiaur; M Izquierdo; C Terhorst; F Malavasi; J Sancho
J Immunol (1997) 159 (1): 193–205.
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Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones.
F Novelli; M M D'Elios; P Bernabei; L Ozmen; L Rigamonti; F Almerigogna; G Forni; G Del Prete
J Immunol (1997) 159 (1): 206–213.
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Antigen specificity of dual reactive T hybridomas determines the requirement for CD40 ligand-CD40 interactions.
M E Ozaki; L Karlsson; P A Peterson; S R Webb
J Immunol (1997) 159 (1): 214–221.
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Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain.
E Shores; V Flamand; T Tran; A Grinberg; J P Kinet; P E Love
J Immunol (1997) 159 (1): 222–230.
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B cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activation.
B J Vilen; S J Famiglietti; A M Carbone; B K Kay; J C Cambier
J Immunol (1997) 159 (1): 231–243.
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Structural requirements for assembly of dimeric IgA probed by site-directed mutagenesis of J chain and a cysteine residue of the alpha-chain CH2 domain.
S Krugmann; R J Pleass; J D Atkin; J M Woof
J Immunol (1997) 159 (1): 244–249.
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Structure and genomic organization of a second class of immunoglobulin light chain genes in the channel catfish.
S H Ghaffari; C J Lobb
J Immunol (1997) 159 (1): 250–258.
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Isolation and characterization of 2'-fluoro-, 2'-amino-, and 2'-fluoro-/amino-modified RNA ligands to human IFN-gamma that inhibit receptor binding.
M F Kubik; C Bell; T Fitzwater; S R Watson; D M Tasset
J Immunol (1997) 159 (1): 259–267.
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The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1.
C F Lu; T A Springer
J Immunol (1997) 159 (1): 268–278.
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Refocusing neutralizing antibody response by targeted dampening of an immunodominant epitope.
R R Garrity; G Rimmelzwaan; A Minassian; W P Tsai; G Lin; J J de Jong; J Goudsmit; P L Nara
J Immunol (1997) 159 (1): 279–289.
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Human alveolar T lymphocyte responses to Mycobacterium tuberculosis antigens: role for CD4+ and CD8+ cytotoxic T cells and relative resistance of alveolar macrophages to lysis.
J S Tan; D H Canaday; W H Boom; K N Balaji; S K Schwander; E A Rich
J Immunol (1997) 159 (1): 290–297.
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Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes.
S Stoll; G Müller; M Kurimoto; J Saloga; T Tanimoto; H Yamauchi; H Okamura; J Knop; A H Enk
J Immunol (1997) 159 (1): 298–302.
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The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes.
P F Robbins; M El-Gamil; Y F Li; E B Fitzgerald; Y Kawakami; S A Rosenberg
J Immunol (1997) 159 (1): 303–308.
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NKR-P1A stimulation of arachidonate-generating enzymes in rat NK cells is associated with granule release and cytotoxic activity.
M Grazia Cifone; P Roncaioli; L Cironi; C Festuccia; A Meccia; S D'Aló; D Botti; A Santoni
J Immunol (1997) 159 (1): 309–317.
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Macrophage inflammatory protein-1alpha (MIP-1alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Cryptococcus neoformans infection.
G B Huffnagle; R M Strieter; L K McNeil; R A McDonald; M D Burdick; S L Kunkel; G B Toews
J Immunol (1997) 159 (1): 318–327.
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IL-12 treatment attenuates T helper cell type 2 and B cell responses but does not improve vaccine-enhanced lung illness.
T Hussell; U Khan; P Openshaw
J Immunol (1997) 159 (1): 328–334.
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Determinants of T cell reactivity to the Mycobacterium leprae GroES homologue.
J Kim; A Sette; S Rodda; S Southwood; P A Sieling; V Mehra; J D Ohmen; J Oliveros; E Appella; Y Higashimoto; T H Rea; B R Bloom; R L Modlin
J Immunol (1997) 159 (1): 335–343.
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Differential CD45 isoform expression accompanies reduced natural antibody binding in L5178Y-F9 tumor progression.
Z Y Zhang; D A Chow
J Immunol (1997) 159 (1): 344–350.
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Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer.
L Chen; D Chen; E Block; M O'Donnell; D W Kufe; S K Clinton
J Immunol (1997) 159 (1): 351–359.
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A mechanism for selective recruitment of CD8 T cells into B7-1-transfected plasmacytoma: role of macrophage-inflammatory protein 1alpha.
M Maric; L Chen; B Sherry; Y Liu
J Immunol (1997) 159 (1): 360–368.
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Expression of a biologically active recombinant mouse IL-1 receptor antagonist and its use in vivo to modulate aspects of the acute phase response.
S Grehan; C M Uhlar; R B Sim; J Herbert; A S Whitehead
J Immunol (1997) 159 (1): 369–378.
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IL-13 inhibits TNF production but potentiates that of IL-6 in vivo and ex vivo in mice.
E Di Santo; C Meazza; M Sironi; P Fruscella; A Mantovani; J D Sipe; P Ghezzi
J Immunol (1997) 159 (1): 379–382.
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Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin.
V C Ridger; E R Pettipher; C E Bryant; S D Brain
J Immunol (1997) 159 (1): 383–390.
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Endotoxin induces expression of type II phospholipase A2 in macrophages during acute lung injury in guinea pigs: involvement of TNF-alpha in lipopolysaccharide-induced type II phospholipase A2 synthesis.
L Arbibe; D Vial; I Rosinski-Chupin; N Havet; M Huerre; B B Vargaftig; L Touqui
J Immunol (1997) 159 (1): 391–400.
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Transgenic monocyte chemoattractant protein-1 (MCP-1) in pancreatic islets produces monocyte-rich insulitis without diabetes: abrogation by a second transgene expressing systemic MCP-1.
I S Grewal; B J Rutledge; J A Fiorillo; L Gu; R P Gladue; R A Flavell; B J Rollins
J Immunol (1997) 159 (1): 401–408.
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Fc receptor-triggered insertion of secretory granules into the plasma membrane of human neutrophils: selective retrieval during phagocytosis.
H Tapper; S Grinstein
J Immunol (1997) 159 (1): 409–418.
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Differential regulation of indoleamine 2,3-dioxygenase expression by nitric oxide and inflammatory mediators in IFN-gamma-activated murine macrophages and microglial cells.
D Alberati-Giani; P Malherbe; P Ricciardi-Castagnoli; C Köhler; S Denis-Donini; A M Cesura
J Immunol (1997) 159 (1): 419–426.
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Shared TCR Vbeta gene expression by the pancreas and salivary gland in immunodeficient alymphoplasic mice.
M Yamamichi; N Matsuoka; T Tomioka; K Eguchi; S Nagataki; T Kanematsu
J Immunol (1997) 159 (1): 427–432.
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Outside-in signaling by lipopolysaccharide through a tailless integrin.
R R Ingalls; M A Arnaout; D T Golenbock
J Immunol (1997) 159 (1): 433–438.
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Cyclooxygenase-2-dependent delayed prostaglandin D2 generation is initiated by nerve growth factor in rat peritoneal mast cells: its augmentation by extracellular type II secretory phospholipase A2.
M Murakami; K Tada; K Nakajima; I Kudo
J Immunol (1997) 159 (1): 439–446.
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Recombinant histamine-releasing factor enhances IgE-dependent IL-4 and IL-13 secretion by human basophils.
J T Schroeder; L M Lichtenstein; S M MacDonald
J Immunol (1997) 159 (1): 447–452.
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Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity.
C Mohan; L Morel; P Yang; E K Wakeland
J Immunol (1997) 159 (1): 454–465.
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Role of macrophages and macrophage-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes in diabetes-resistant BioBreeding rats.
Y H Chung; H S Jun; Y Kang; K Hirasawa; B R Lee; N Van Rooijen; J W Yoon
J Immunol (1997) 159 (1): 466–471.
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Identification of rat prostatic steroid-binding protein as a target antigen of experimental autoimmune prostatitis: implications for prostate cancer therapy.
K J Liu; G S Chatta; D R Twardzik; T S Vedvick; L D True; A G Spies; M A Cheever
J Immunol (1997) 159 (1): 472–480.
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Clonal expansion of CD8+ T cells in Kawasaki disease.
I H Choi; Y J Chwae; W S Shim; D S Kim; D H Kwon; J D Kim; S J Kim
J Immunol (1997) 159 (1): 481–486.
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A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth.
D F Jelinek; T E Witzig; B K Arendt
J Immunol (1997) 159 (1): 487–496.
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Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis.
T Brabb; A W Goldrath; P von Dassow; A Paez; H D Liggitt; J Goverman
J Immunol (1997) 159 (1): 497–507.
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