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Volume 159, Issue 5

1 September 1997

ISSN 0022-1767

EISSN 1550-6606

In this Issue

CUTTING EDGE
ARTICLES

CUTTING EDGE

Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts.

F Vély; E Vivier

J Immunol (1997) 159 (5): 2075–2077.

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Induction of thymocyte deletion by purified single peptide/major histocompatibility complex ligands.

S Lesage; J Charron; G Winslow; P Hugo

J Immunol (1997) 159 (5): 2078–2081.

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Protein kinase C alpha-mediated chronic signal transduction for immunosenescence.

K Ohkusu; J Du; K I Isobe; H Yi; A A Akhand; M Kato; H Suzuki; H Hidaka; I Nakashima

J Immunol (1997) 159 (5): 2082–2084.

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ARTICLES

Memory, but not naive, peripheral blood B lymphocytes differentiate into Ig-secreting cells after CD40 ligation and costimulation with IL-4 and the differentiation factors IL-2, IL-10, and IL-3.

V Kindler; R H Zubler

J Immunol (1997) 159 (5): 2085–2090.

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Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells.

N S Williams; V H Engelhard

J Immunol (1997) 159 (5): 2091–2099.

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Positive and negative selection of functional mouse CD4 cells by porcine MHC in pig thymus grafts.

Y Zhao; J J Sergio; K Swenson; J S Arn; D H Sachs; M Sykes

J Immunol (1997) 159 (5): 2100–2107.

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Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by soluble recombinant CD95 ligand.

F Zipp; R Martin; R Lichtenfels; W Roth; J Dichgans; P H Krammer; M Weller

J Immunol (1997) 159 (5): 2108–2115.

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Amplified follicular immune complex deposition in mice lacking the Fc receptor gamma-chain does not alter maturation of the B cell response.

K A Vora; J V Ravetch; T Manser

J Immunol (1997) 159 (5): 2116–2124.

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A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.

H J Ahn; S Maruo; M Tomura; J Mu; T Hamaoka; K Nakanishi; S Clark; M Kurimoto; H Okamura; H Fujiwara

J Immunol (1997) 159 (5): 2125–2131.

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CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells.

C Andrews; S L Swain; G Muralidhar

J Immunol (1997) 159 (5): 2132–2138.

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The effect of the proteasome inhibitor lactacystin on the presentation of transporter associated with antigen processing (TAP)-dependent and TAP-independent peptide epitopes by class I molecules.

A Bai; J Forman

J Immunol (1997) 159 (5): 2139–2146.

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Non-MHC-linked Th2 cell development induced by soluble protein administration predicts susceptibility to Leishmania major infection.

J C Guéry; F Galbiati; S Smiroldo; L Adorini

J Immunol (1997) 159 (5): 2147–2153.

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CD94 ligation induces apoptosis in a subset of IL-2-stimulated NK cells.

H Ida; M J Robertson; S Voss; J Ritz; P Anderson

J Immunol (1997) 159 (5): 2154–2160.

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Interleukin-11 inhibits macrophage interleukin-12 production.

S X Leng; J A Elias

J Immunol (1997) 159 (5): 2161–2168.

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CD28-induced cytokine production and proliferation by thymocytes are differentially regulated by the p59fyn tyrosine kinase.

C J Ong; A S Lim; H S Teh

J Immunol (1997) 159 (5): 2169–2176.

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Impaired class II expression and antigen uptake in monocytic cells after HIV-1 infection.

S Polyak; H Chen; D Hirsch; I George; R Hershberg; K Sperber

J Immunol (1997) 159 (5): 2177–2188.

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T cells bearing Vbeta8 are preferentially infected with exogenous mouse mammary tumor virus.

N Upragarin; H Nishimura; W Wajjwalku; Y Ando; S Nagafuchi; T Watanabe; Y Yoshikai

J Immunol (1997) 159 (5): 2189–2195.

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Fas ligand expression is restricted to nonlymphoid thymic components in situ.

L E French; A Wilson; M Hahne; I Viard; J Tschopp; H R MacDonald

J Immunol (1997) 159 (5): 2196–2202.

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Antibodies against sialophorin (CD43) enhance the capacity of dendritic cells to cluster and activate T lymphocytes.

E Fanales-Belasio; G Zambruno; A Cavani; G Girolomoni

J Immunol (1997) 159 (5): 2203–2211.

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IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.

A Ogata; D Chauhan; G Teoh; S P Treon; M Urashima; R L Schlossman; K C Anderson

J Immunol (1997) 159 (5): 2212–2221.

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Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

B Pulendran; J Lingappa; M K Kennedy; J Smith; M Teepe; A Rudensky; C R Maliszewski; E Maraskovsky

J Immunol (1997) 159 (5): 2222–2231.

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Distinct mechanisms for the induction and maintenance of allograft tolerance with CTLA4-Fc treatment.

H M Tran; P W Nickerson; A C Restifo; M A Ivis-Woodward; A Patel; R D Allen; T B Strom; P J O'Connell

J Immunol (1997) 159 (5): 2232–2239.

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Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1.

H Chen; W E Paul

J Immunol (1997) 159 (5): 2240–2249.

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CD99 (MIC2) regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes, and its gene encodes both positive and negative regulators of cellular adhesion.

J H Hahn; M K Kim; E Y Choi; S H Kim; H W Sohn; D I Ham; D H Chung; T J Kim; W J Lee; C K Park; H J Ree; S H Park

J Immunol (1997) 159 (5): 2250–2258.

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IL-7 activates alpha4beta1 integrin in murine thymocytes.

H Kitazawa; K Muegge; R Badolato; J M Wang; W E Fogler; D K Ferris; C K Lee; S Candéias; M R Smith; J J Oppenheim; S K Durum

J Immunol (1997) 159 (5): 2259–2264.

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The proliferative in vivo activities of lpr double-negative T cells and the primary role of p59fyn in their activation and expansion.

D Balomenos; R Rumold; A N Theofilopoulos

J Immunol (1997) 159 (5): 2265–2273.

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Convergence of Schiff base costimulatory signaling and TCR signaling at the level of mitogen-activated protein kinase ERK2.

H Chen; S Hall; B Heffernan; N T Thompson; M V Rogers; J Rhodes

J Immunol (1997) 159 (5): 2274–2281.

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CD40 ligand induction on T cell subsets by peptide-presenting B cells: implications for development of the primary T and B cell response.

A I Jaiswal; M Croft

J Immunol (1997) 159 (5): 2282–2291.

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The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production.

L A Lewis; C D Chung; J Chen; J R Parnes; M Moran; V P Patel; M C Miceli

J Immunol (1997) 159 (5): 2292–2300.

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Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo.

L A O'Reilly; A W Harris; D M Tarlinton; L M Corcoran; A Strasser

J Immunol (1997) 159 (5): 2301–2311.

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Functional mapping of the orientation for TCR recognition of an H2-Kb-restricted ovalbumin peptide suggests that the beta-chain subunit can dominate the determination of peptide side chain specificity.

S J Turner; S C Jameson; F R Carbone

J Immunol (1997) 159 (5): 2312–2317.

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Analysis of polymorphism in porcine MHC class I genes: alterations in signals recognized by human cytotoxic lymphocytes.

J A Sullivan; H F Oettinger; D H Sachs; A S Edge

J Immunol (1997) 159 (5): 2318–2326.

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The glycosylation of IgA produced by murine B cells is altered by Th2 cytokines.

S R Chintalacharuvu; S N Emancipator

J Immunol (1997) 159 (5): 2327–2333.

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T cell-independent response to Brucella-insulin identifies a preimmune repertoire for insulin.

J W Thomas; P M Kralick; U K Ewulonu

J Immunol (1997) 159 (5): 2334–2341.

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Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

J P Arm; C Nwankwo; K F Austen

J Immunol (1997) 159 (5): 2342–2349.

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Absence of functional relevance of human transporter associated with antigen processing polymorphism for peptide selection.

S Daniel; S Caillat-Zucman; J Hammer; J F Bach; P M van Endert

J Immunol (1997) 159 (5): 2350–2357.

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Assembly and retention of CD1b heavy chains in the endoplasmic reticulum.

M Sugita; S A Porcelli; M B Brenner

J Immunol (1997) 159 (5): 2358–2365.

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Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201-restricted Melan-A/MART-1 antigenic peptide in melanoma.

P Romero; N Gervois; J Schneider; P Escobar; D Valmori; C Pannetier; A Steinle; T Wolfel; D Lienard; V Brichard; A van Pel; F Jotereau; J C Cerottini

J Immunol (1997) 159 (5): 2366–2374.

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Heat shock protein 65 induced by gammadelta T cells prevents apoptosis of macrophages and contributes to host defense in mice infected with Toxoplasma gondii.

H Hisaeda; T Sakai; H Ishikawa; Y Maekawa; K Yasutomo; R A Good; K Himeno

J Immunol (1997) 159 (5): 2375–2381.

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Superantigen activation of immune cells evokes epithelial (T84) transport and barrier abnormalities via IFN-gamma and TNF alpha: inhibition of increased permeability, but not diminished secretory responses by TGF-beta2.

D M McKay; P K Singh

J Immunol (1997) 159 (5): 2382–2390.

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Chimeric peptides: a new approach to enhancing the immunogenicity of peptides with low MHC class I affinity: application in antiviral vaccination.

S Tourdot; M Oukka; J C Manuguerra; V Magafa; I Vergnon; N Riché; M Bruley-Rosset; P Cordopatis; K Kosmatopoulos

J Immunol (1997) 159 (5): 2391–2398.

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Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity.

L B Gordon; S C Nolan; H F Cserr; P M Knopf; C J Harling-Berg

J Immunol (1997) 159 (5): 2399–2408.

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Adsorption to aluminum hydroxide promotes the activity of IL-12 as an adjuvant for antibody as well as type 1 cytokine responses to HIV-1 gp120.

D Jankovic; P Caspar; M Zweig; M Garcia-Moll; S D Showalter; F R Vogel; A Sher

J Immunol (1997) 159 (5): 2409–2417.

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Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1.

Y H Hong; H B Peng; V La Fata; J K Liao

J Immunol (1997) 159 (5): 2418–2423.

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Human monocyte binding to fibronectin enhances IFN-gamma-induced early signaling events.

J B McCarthy; B V Vachhani; S M Wahl; D S Finbloom; G M Feldman

J Immunol (1997) 159 (5): 2424–2430.

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Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6.

C D Richards; C Kerr; M Tanaka; T Hara; A Miyajima; D Pennica; F Botelho; C M Langdon

J Immunol (1997) 159 (5): 2431–2437.

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Characterization of C3-binding proteins on mouse neutrophils and platelets.

R J Quigg; J J Alexander; C F Lo; A Lim; C He; V M Holers

J Immunol (1997) 159 (5): 2438–2444.

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Enhanced expression of inducible cyclooxygenase with age in murine macrophages.

M G Hayek; C Mura; D Wu; A A Beharka; S N Han; K E Paulson; D Hwang; S N Meydani

J Immunol (1997) 159 (5): 2445–2451.

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Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice.

M Labow; D Shuster; M Zetterstrom; P Nunes; R Terry; E B Cullinan; T Bartfai; C Solorzano; L L Moldawer; R Chizzonite; K W McIntyre

J Immunol (1997) 159 (5): 2452–2461.

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Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production.

Y Shibata; W J Metzger; Q N Myrvik

J Immunol (1997) 159 (5): 2462–2467.

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Bridging of neutrophils to target cells by opsonized zymosan enhances the cytotoxicity of neutrophil-produced H2O2.

X Jiang; T H Wu; R L Rubin

J Immunol (1997) 159 (5): 2468–2475.

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In vivo transfer of engineered macrophages into the glomerulus: endogenous TGF-beta-mediated defense against macrophage-induced glomerular cell activation.

T S Sütö; L G Fine; F Shimizu; M Kitamura

J Immunol (1997) 159 (5): 2476–2483.

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Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile.

H Kitagaki; N Ono; K Hayakawa; T Kitazawa; K Watanabe; T Shiohara

J Immunol (1997) 159 (5): 2484–2491.

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Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages.

J Hodge-Dufour; P W Noble; M R Horton; C Bao; M Wysoka; M D Burdick; R M Strieter; G Trinchieri; E Puré

J Immunol (1997) 159 (5): 2492–2500.

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Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99.

L J Ausubel; J I Krieger; D A Hafler

J Immunol (1997) 159 (5): 2502–2512.

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Functional heterogeneity of HLA-A*02 subtypes revealed by presentation of a MAGE-3-encoded peptide to cytotoxic T cell clones.

K Fleischhauer; S Tanzarella; V Russo; M L Sensi; P van der Bruggen; C Bordignon; C Traversari

J Immunol (1997) 159 (5): 2513–2521.

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Prevention by anti-LFA-1 of acute myoblast death following transplantation.

B Guérette; D Skuk; F Célestin; C Huard; F Tardif; I Asselin; B Roy; M Goulet; R Roy; M Entman; J P Tremblay

J Immunol (1997) 159 (5): 2522–2531.

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Suppression of autoimmune disease and of massive lymphadenopathy in MRL/Mp-lpr/lpr mice lacking tyrosine kinase Fyn (p59fyn).

T Takahashi; T Yagi; S Kakinuma; A Kurokawa; T Okada; K Takatsu; S Aizawa; T Katagiri

J Immunol (1997) 159 (5): 2532–2541.

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