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Volume 159, Issue 9

1 November 1997

ISSN 0022-1767

EISSN 1550-6606

In this Issue

CUTTING EDGE
ARTICLES

CUTTING EDGE

Ig Sgamma3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination.

R A Wuerffel; J Du; R J Thompson; A L Kenter

J Immunol (1997) 159 (9): 4139–4144.

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The PU.1 binding site is a cis-element that regulates pro-B/pre-B specificity of Vkappa-Jkappa joining.

R Hayashi; T Takemori; M Kodama; M Suzuki; A Tsuboi; F Nagawa; H Sakano

J Immunol (1997) 159 (9): 4145–4149.

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Regulation of C-C chemokine production by murine T cells by CD28/B7 costimulation.

K C Herold; J Lu; I Rulifson; V Vezys; D Taub; M J Grusby; J A Bluestone

J Immunol (1997) 159 (9): 4150–4153.

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ARTICLES

Effect of TGF-beta1 on cell cycle regulatory proteins in LPS-stimulated normal mouse B lymphocytes.

C Bouchard; W H Fridman; C Sautès

J Immunol (1997) 159 (9): 4155–4164.

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Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis.

M F Bachmann; T Ohteki; K M Faienza; A Zakarian; D Kägi; D E Speiser; P S Ohashi

J Immunol (1997) 159 (9): 4165–4170.

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Stromal cell modulation of negative regulatory signals that influence apoptosis and proliferation of B lineage lymphocytes.

L A Borghesi; G Smithson; P W Kincade

J Immunol (1997) 159 (9): 4171–4179.

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CD4+ T cells from IRF-1-deficient mice exhibit altered patterns of cytokine expression and cell subset homeostasis.

D L McElligott; J A Phillips; C A Stillman; R J Koch; D E Mosier; M V Hobbs

J Immunol (1997) 159 (9): 4180–4186.

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Differential tyrosine phosphorylation of inhibitory versus activating Ly-49 receptor proteins and their recruitment of SHP-1 phosphatase.

L H Mason; P Gosselin; S K Anderson; W E Fogler; J R Ortaldo; D W McVicar

J Immunol (1997) 159 (9): 4187–4196.

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Fas-mediated liver damage in MRL hemopoietic chimeras undergoing lpr-mediated graft-versus-host disease.

P Bobé; D Bonardelle; M Reynès; F Godeau; J Mahiou; V Joulin; N Kiger

J Immunol (1997) 159 (9): 4197–4204.

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Limits to the differential avidity model of T cell selection in the thymus.

C Girao; Q Hu; J Sun; P G Ashton-Rickardt

J Immunol (1997) 159 (9): 4205–4211.

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Differential effects of B7-1 blockade in the rat experimental autoimmune encephalomyelitis model.

L Gallon; A Chandraker; S Issazadeh; R Peach; P S Linsley; L A Turka; M H Sayegh; S J Khoury

J Immunol (1997) 159 (9): 4212–4216.

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Distinct roles for B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity.

H Xu; P S Heeger; R L Fairchild

J Immunol (1997) 159 (9): 4217–4226.

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TCR-beta repertoire development in the mouse embryo.

H Ema; A Cumano; P Kourilsky

J Immunol (1997) 159 (9): 4227–4232.

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B cell antigen receptor-evoked calcium influx is enhanced in CD22-deficient B cell lines.

M J Nadler; P A McLean; B G Neel; H H Wortis

J Immunol (1997) 159 (9): 4233–4243.

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CD40-mediated signals inhibit the binding of TNF receptor-associated factor 2 to the CD40 cytoplasmic domain.

A Chaudhuri; S Orme; S Eilam; B J Cherayil

J Immunol (1997) 159 (9): 4244–4251.

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Transgenic expression of lymphotoxin restores lymph nodes to lymphotoxin-alpha-deficient mice.

R Sacca; S Turley; L Soong; I Mellman; N H Ruddle

J Immunol (1997) 159 (9): 4252–4260.

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Specific resistance of T cells to CD95-induced apoptosis during S phase of the cell cycle.

T Dao; J W Huleatt; R Hingorani; I N Crispe

J Immunol (1997) 159 (9): 4261–4267.

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In vivo administration of flt3 ligand markedly stimulates generation of dendritic cell progenitors from mouse liver.

M L Drakes; L Lu; V M Subbotin; A W Thomson

J Immunol (1997) 159 (9): 4268–4278.

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Regulation of B cell functions by C3a and C3a(desArg): suppression of TNF-alpha, IL-6, and the polyclonal immune response.

W H Fischer; T E Hugli

J Immunol (1997) 159 (9): 4279–4286.

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Cellular requirements for the activation and proliferation of ruminant gammadelta T cells.

C F Hanrahan; W G Kimpton; C J Howard; K R Parsons; M R Brandon; A E Andrews; A D Nash

J Immunol (1997) 159 (9): 4287–4294.

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Activation and migration of CD8 T cells in the intestinal mucosa.

S K Kim; D S Reed; W R Heath; F Carbone; L Lefrançois

J Immunol (1997) 159 (9): 4295–4306.

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The cytoplasmic domain of CD5 mediates both TCR/CD3-dependent and -independent diacylglycerol production.

M Simarro; C Pelassy; J Calvo; L Places; C Aussel; F Lozano

J Immunol (1997) 159 (9): 4307–4315.

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Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule.

J M Carballido; G Aversa; K Kaltoft; B G Cocks; J Punnonen; H Yssel; K Thestrup-Pedersen; J E de Vries

J Immunol (1997) 159 (9): 4316–4321.

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Cloning and analysis of the promoter region of CXCR4, a coreceptor for HIV-1 entry.

M Moriuchi; H Moriuchi; W Turner; A S Fauci

J Immunol (1997) 159 (9): 4322–4329.

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Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM: studies of diffusion, binding to the human polymeric Ig receptor, and epithelial transcytosis.

I B Natvig; F E Johansen; T W Nordeng; G Haraldsen; P Brandtzaeg

J Immunol (1997) 159 (9): 4330–4340.

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Human T cell leukemias with continuous V(D)J recombinase activity for TCR-delta gene deletion.

T M Breit; M C Verschuren; I L Wolvers-Tettero; E J Van Gastel-Mol; K Hählen; J J van Dongen

J Immunol (1997) 159 (9): 4341–4349.

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Induction of STAT protein signaling through the CD40 receptor in B lymphocytes: distinct STAT activation following surface Ig and CD40 receptor engagement.

J G Karras; Z Wang; L Huo; D A Frank; T L Rothstein

J Immunol (1997) 159 (9): 4350–4355.

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Alteration of glycosylation renders HIV sensitive to inactivation by normal human serum.

D J Reed; X Lin; T D Thomas; C W Birks; J Tang; R P Rother

J Immunol (1997) 159 (9): 4356–4361.

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Recombining sequence recombination in normal kappa-chain-expressing B cells.

O Dunda; D Corcos

J Immunol (1997) 159 (9): 4362–4366.

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Cloning and expression of the dog mast cell alpha-chymase gene.

G H Caughey; J L Blount; K L Koerber; M Kitamura; K C Fang

J Immunol (1997) 159 (9): 4367–4375.

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Embryonic stem cell lines from MRL mice allow genetic modification in a murine model of autoimmune disease.

J L Goulet; C Y Wang; B H Koller

J Immunol (1997) 159 (9): 4376–4381.

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Cloning and characterization of the human recombination activating gene 1 (RAG1) and RAG2 promoter regions.

A A Zarrin; I Fong; L Malkin; P A Marsden; N L Berinstein

J Immunol (1997) 159 (9): 4382–4394.

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The orientation of a T cell receptor to its MHC class II:peptide ligands.

S C Hong; D B Sant'Angelo; B N Dittel; R Medzhitov; S T Yoon; P G Waterbury; C A Janeway, Jr

J Immunol (1997) 159 (9): 4395–4402.

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Somatic hypermutation: mutations 3' of rabbit VDJ H-chain genes.

D K Lanning; K L Knight

J Immunol (1997) 159 (9): 4403–4407.

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Rigidification of the alpha2 helix of an MHC class I molecule by a valine to proline mutation in position 165 does not prevent peptide-specific antigen presentation.

D Plaksin; K Polakova; M G Mage; D H Margulies

J Immunol (1997) 159 (9): 4408–4414.

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T cell receptor-mediated signaling is defective in T cells obtained from patients with primary intracranial tumors.

L A Morford; L H Elliott; S L Carlson; W H Brooks; T L Roszman

J Immunol (1997) 159 (9): 4415–4425.

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Syk-independent tyrosine phosphorylation and association of the protein tyrosine phosphatases SHP-1 and SHP-2 with the high affinity IgE receptor.

T Kimura; J Zhang; K Sagawa; K Sakaguchi; E Appella; R P Siraganian

J Immunol (1997) 159 (9): 4426–4434.

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Intracytoplasmic delivery of listeriolysin O by a vaccinal strain of Bacillus anthracis induces CD8-mediated protection against Listeria monocytogenes.

J C Sirard; C Fayolle; C de Chastellier; M Mock; C Leclerc; P Berche

J Immunol (1997) 159 (9): 4435–4443.

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The surface glycoproteins of Trypanosoma cruzi encode a superfamily of variant T cell epitopes.

S J Kahn; M Wleklinski

J Immunol (1997) 159 (9): 4444–4451.

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Intracellular fate of vacuoles containing Toxoplasma gondii is determined at the time of formation and depends on the mechanism of entry.

D G Mordue; L D Sibley

J Immunol (1997) 159 (9): 4452–4459.

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B7-2 blockade enhances T cell responses to Leishmania donovani.

M L Murphy; C R Engwerda; P M Gorak; P M Kaye

J Immunol (1997) 159 (9): 4460–4466.

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Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis.

C I Brodskyn; A Barral; V Boaventura; E Carvalho; M Barral-Netto

J Immunol (1997) 159 (9): 4467–4473.

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Reversal reaction in borderline leprosy is associated with a polarized shift to type 1-like Mycobacterium leprae T cell reactivity in lesional skin: a follow-up study.

C E Verhagen; E A Wierenga; A A Buffing; M A Chand; W R Faber; P K Das

J Immunol (1997) 159 (9): 4474–4483.

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TGF-beta induced by oral tolerance ameliorates experimental tracheal eosinophilia.

K Haneda; K Sano; G Tamura; T Sato; S Habu; K Shirato

J Immunol (1997) 159 (9): 4484–4490.

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Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages.

B W Winston; E D Chan; G L Johnson; D W Riches

J Immunol (1997) 159 (9): 4491–4497.

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Sensitive responses of leukocytes to lipopolysaccharide require a protein distinct from CD14 at the cell surface.

T Vasselon; R Pironkova; P A Detmers

J Immunol (1997) 159 (9): 4498–4505.

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Mechanism of suppression of macrophage nitric oxide release by IL-13: influence of the macrophage population.

C Bogdan; H Thüring; M Dlaska; M Röllinghoff; G Weiss

J Immunol (1997) 159 (9): 4506–4513.

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Differential roles of selectins and the alpha4-integrin in acute, subacute, and chronic leukocyte recruitment in vivo.

B Johnston; U M Walter; A C Issekutz; T B Issekutz; D C Anderson; P Kubes

J Immunol (1997) 159 (9): 4514–4523.

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The fate of pro-TNF-alpha following inhibition of metalloprotease-dependent processing to soluble TNF-alpha in human monocytes.

K A Solomon; M B Covington; C P DeCicco; R C Newton

J Immunol (1997) 159 (9): 4524–4531.

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TNF-alpha and IL-4 synergistically increase vascular cell adhesion molecule-1 expression in cultured vascular smooth muscle cells.

J L Barks; J J McQuillan; M F Iademarco

J Immunol (1997) 159 (9): 4532–4538.

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Distinct CD4+ T cell helper requirements in Theileria parva-immune and -naive bovine CTL precursors.

E L Taracha; E Awino; D J McKeever

J Immunol (1997) 159 (9): 4539–4545.

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Expression of vascular cell adhesion molecule-1 by vascular endothelial cells in immune and nonimmune inflammatory reactions in the skin.

A A Harrison; C J Stocker; P T Chapman; Y T Tsang; T Y Huehns; R H Gundel; A M Peters; K A Davies; A J George; M K Robinson; D O Haskard

J Immunol (1997) 159 (9): 4546–4554.

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Comparison of tethering and rolling of eosinophils and neutrophils through selectins and P-selectin glycoprotein ligand-1.

K D Patel; R P McEver

J Immunol (1997) 159 (9): 4555–4565.

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Synergy between L-selectin signaling and chemotactic activation during neutrophil adhesion and transmigration.

Y T Tsang; S Neelamegham; Y Hu; E L Berg; A R Burns; C W Smith; S I Simon

J Immunol (1997) 159 (9): 4566–4577.

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CD40 ligand expressed on B cells in the BXSB mouse model of systemic lupus erythematosus.

S Blossom; E B Chu; W O Weigle; K M Gilbert

J Immunol (1997) 159 (9): 4580–4586.

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Regulation of anti-HIV-1 activity of RANTES by heparan sulfate proteoglycans.

T Oravecz; M Pall; J Wang; G Roderiquez; M Ditto; M A Norcross

J Immunol (1997) 159 (9): 4587–4592.

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Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation.

B Lamkhioued; P M Renzi; S Abi-Younes; E A Garcia-Zepada; Z Allakhverdi; O Ghaffar; M D Rothenberg; A D Luster; Q Hamid

J Immunol (1997) 159 (9): 4593–4601.

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Myelin protein expression is increased in lymph nodes of mice with relapsing experimental autoimmune encephalomyelitis.

A J MacKenzie-Graham; T M Pribyl; S Kim; V R Porter; A T Campagnoni; R R Voskuhl

J Immunol (1997) 159 (9): 4602–4610.

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Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA- memory T cells.

M Akdis; C A Akdis; L Weigl; R Disch; K Blaser

J Immunol (1997) 159 (9): 4611–4619.

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CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice.

B Balasa; T Krahl; G Patstone; J Lee; R Tisch; H O McDevitt; N Sarvetnick

J Immunol (1997) 159 (9): 4620–4627.

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Fas ligand expression and function in systemic lupus erythematosus.

J McNally; D H Yoo; J Drappa; J L Chu; H Yagita; S M Friedman; K B Elkon

J Immunol (1997) 159 (9): 4628–4636.

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