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Molecular Basis of Human Complement C1s Deficiency

Yuichi Endo; Kazuko Kanno; Minoru Takahashi; Ken-ichi Yamaguchi; Yoichi Kohno; Teizo Fujita

J Immunol (1999) 162 (4): 2180–2183.

Abstract

View articletitled, Molecular Basis of Human Complement C1s Deficiency

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TCR Vaccines Against T Cell Lymphoma: QS-21 and IL-12 Adjuvants Induce a Protective CD8⁺ T Cell Response ¹

Carmen P. Wong; Craig Y. Okada; Ronald Levy

J Immunol (1999) 162 (4): 2251–2258.

Abstract

View articletitled, TCR Vaccines Against T Cell Lymphoma: QS-21 and IL-12 Adjuvants Induce a Protective CD8+ T Cell Response<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evidence of Positive Cross-Regulation on Th1 by Th2 and Antigen-Presenting Cells: Effects on Th1 Induced by IL-4 and IL-12 ¹

Timothy B. Oriss; Susan A. McCarthy; Martha A. K. Campana; Penelope A. Morel

J Immunol (1999) 162 (4): 1999–2007.

Abstract

View articletitled, Evidence of Positive Cross-Regulation on Th1 by Th2 and Antigen-Presenting Cells: Effects on Th1 Induced by IL-4 and IL-12<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Anti-ICAM-1 Monoclonal Antibody R6.5 (Enlimomab) Promotes Activation of Neutrophils in Whole Blood ¹

Juha Vuorte; Perttu J. Lindsberg; Markku Kaste; Seppo Meri; Sten-Erik Jansson; Robert Rothlein; Heikki Repo

J Immunol (1999) 162 (4): 2353–2357.

Abstract

View articletitled, Anti-ICAM-1 Monoclonal Antibody R6.5 (Enlimomab) Promotes Activation of Neutrophils in Whole Blood<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-12 Administered During Chlamydia psittaci Lung Infection in Mice Confers Immediate and Long-Term Protection and Reduces Macrophage Inflammatory Protein-2 Level and Neutrophil Infiltration in Lung Tissue ¹

Jin Huang; Ming-Dong Wang; Stephen Lenz; Dongya Gao; Bernhard Kaltenboeck

J Immunol (1999) 162 (4): 2217–2226.

Abstract

View articletitled, IL-12 Administered During Chlamydia psittaci Lung Infection in Mice Confers Immediate and Long-Term Protection and Reduces Macrophage Inflammatory Protein-2 Level and Neutrophil Infiltration in Lung Tissue<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mucosally Induced Systemic T Cell Unresponsiveness to Ovalbumin Requires CD40 Ligand-CD40 Interactions ¹

Mi-Na Kweon; Kohtaro Fujihashi; Yoshio Wakatsuki; Toshiya Koga; Masafumi Yamamoto; Jerry R. McGhee; Hiroshi Kiyono

J Immunol (1999) 162 (4): 1904–1909.

Abstract

View articletitled, Mucosally Induced Systemic T Cell Unresponsiveness to Ovalbumin Requires CD40 Ligand-CD40 Interactions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation?¹

Philippe Saas; José Boucraut; Anne-Lise Quiquerez; Valérie Schnuriger; Gaelle Perrin; Sophie Desplat-Jego; Dominique Bernard; Paul R. Walker; Pierre-Yves Dietrich

J Immunol (1999) 162 (4): 2326–2333.

Abstract

View articletitled, CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation?<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dose-Dependent Induction of Distinct Anergic Phenotypes: Multiple Levels of T Cell Anergy ¹

Leonie S. Taams; Willem van Eden; Marca H. M. Wauben

J Immunol (1999) 162 (4): 1974–1981.

Abstract

View articletitled, Dose-Dependent Induction of Distinct Anergic Phenotypes: Multiple Levels of T Cell Anergy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of the Neutrophil Chemokine KC in the Colon of Mice with Enterocolitis and by Intestinal Epithelial Cell Lines: Effects of Flora and Proinflammatory Cytokines ¹

Fei Song; Komei Ito; Tim L. Denning; David Kuninger; John Papaconstantinou; William Gourley; Gary Klimpel; Edward Balish; James Hokanson; Peter B. Ernst

J Immunol (1999) 162 (4): 2275–2280.

Abstract

View articletitled, Expression of the Neutrophil Chemokine KC in the Colon of Mice with Enterocolitis and by Intestinal Epithelial Cell Lines: Effects of Flora and Proinflammatory Cytokines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Increased TNF-α-Induced Apoptosis in Lymphocytes from Aged Humans: Changes in TNF-α Receptor Expression and Activation of Caspases

Sudeepta Aggarwal; Sastry Gollapudi; Sudhir Gupta

J Immunol (1999) 162 (4): 2154–2161.

Abstract

View articletitled, Increased TNF-α-Induced Apoptosis in Lymphocytes from Aged Humans: Changes in TNF-α Receptor Expression and Activation of Caspases

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Determinant Spreading Associated with Demyelination in a Nonhuman Primate Model of Multiple Sclerosis

Hugh I. McFarland; Adrian A. Lobito; Michele M. Johnson; Jeffrey T. Nyswaner; Joseph A. Frank; Gregory R. Palardy; Nancy Tresser; Claude P. Genain; John P. Mueller; Louis A. Matis; Michael J. Lenardo

J Immunol (1999) 162 (4): 2384–2390.

Abstract

View articletitled, Determinant Spreading Associated with Demyelination in a Nonhuman Primate Model of Multiple Sclerosis

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Two Human Neonatal IgM Antibodies Encoded by Different Variable-Region Genes Bind the Same Linear Peptide: Evidence for a Stereotyped Repertoire of Epitope Recognition ¹

Bradley T. Messmer; James J. Sullivan; Nicholas Chiorazzi; Toby C. Rodman; David S. Thaler

J Immunol (1999) 162 (4): 2184–2192.

Abstract

View articletitled, Two Human Neonatal IgM Antibodies Encoded by Different Variable-Region Genes Bind the Same Linear Peptide: Evidence for a Stereotyped Repertoire of Epitope Recognition<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Adjuvanticity of the Cholera Toxin A1-Based Gene Fusion Protein, CTA1-DD, Is Critically Dependent on the ADP-Ribosyltransferase and Ig-Binding Activity ¹

Lena C. Ågren; Lena Ekman; Björn Löwenadler; John G. Nedrud; Nils Y. Lycke

J Immunol (1999) 162 (4): 2432–2440.

Abstract

View articletitled, Adjuvanticity of the Cholera Toxin A1-Based Gene Fusion Protein, CTA1-DD, Is Critically Dependent on the ADP-Ribosyltransferase and Ig-Binding Activity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Bacterial Superantigens Induce Down-Modulation of CC Chemokine Responsiveness in Human Monocytes Via an Alternative Chemokine Ligand-Independent Mechanism ¹

Rahbar Rahimpour; Gordon Mitchell; Masud H. Khandaker; Chen Kong; Bhagirath Singh; Luoling Xu; Atsuo Ochi; Ross D. Feldman; J. Geoffrey Pickering; Bruce M. Gill; David J. Kelvin

J Immunol (1999) 162 (4): 2299–2307.

Abstract

View articletitled, Bacterial Superantigens Induce Down-Modulation of CC Chemokine Responsiveness in Human Monocytes Via an Alternative Chemokine Ligand-Independent Mechanism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Position Effects of Variable Region Carbohydrate on the Affinity and In Vivo Behavior of an Anti-(1→6) Dextran Antibody ¹

M. Josefina Coloma; Ryan K. Trinh; Alexander R. Martinez; Sherie L. Morrison

J Immunol (1999) 162 (4): 2162–2170.

Abstract

View articletitled, Position Effects of Variable Region Carbohydrate on the Affinity and In Vivo Behavior of an Anti-(1→6) Dextran Antibody<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Context-Dependent Immunogenicity of an S206G-Substituted H-2D^b-Restricted Simian Virus 40 Large T Antigen Epitope I Variant ¹

Lawrence M. Mylin

J Immunol (1999) 162 (4): 2171–2179.

Abstract

View articletitled, Context-Dependent Immunogenicity of an S206G-Substituted H-2Db-Restricted Simian Virus 40 Large T Antigen Epitope I Variant<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Anti-KS: Identification of Autoantibodies to Asparaginyl-Transfer RNA Synthetase Associated with Interstitial Lung Disease ¹

Michito Hirakata; Akira Suwa; Sonoko Nagai; Michael A. Kron; Edward P. Trieu; Tsuneyo Mimori; Masashi Akizuki; Ira N. Targoff

J Immunol (1999) 162 (4): 2315–2320.

Abstract

View articletitled, Anti-KS: Identification of Autoantibodies to Asparaginyl-Transfer RNA Synthetase Associated with Interstitial Lung Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunosuppressive Leflunomide Metabolite (A77 1726) Blocks TNF-Dependent Nuclear Factor-κB Activation and Gene Expression ¹

Sunil K. Manna; Bharat B. Aggarwal

J Immunol (1999) 162 (4): 2095–2102.

Abstract

View articletitled, Immunosuppressive Leflunomide Metabolite (A77 1726) Blocks TNF-Dependent Nuclear Factor-κB Activation and Gene Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mitogen-Activated Protein Kinase Activation Through Fcε Receptor I and Stem Cell Factor Receptor Is Differentially Regulated by Phosphatidylinositol 3-Kinase and Calcineurin in Mouse Bone Marrow-Derived Mast Cells ¹

Tamotsu Ishizuka; Kosuke Chayama; Katsuyuki Takeda; Eckard Hamelmann; Naohiro Terada; Gordon M. Keller; Gary L. Johnson; Erwin W. Gelfand

J Immunol (1999) 162 (4): 2087–2094.

Abstract

View articletitled, Mitogen-Activated Protein Kinase Activation Through Fcε Receptor I and Stem Cell Factor Receptor Is Differentially Regulated by Phosphatidylinositol 3-Kinase and Calcineurin in Mouse Bone Marrow-Derived Mast Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Inhibit Endotoxin-Induced TNF-α Production by Macrophages: In Vitro and In Vivo Studies ¹

Mario Delgado; David Pozo; Carmen Martinez; Javier Leceta; Juan Ramon Calvo; Doina Ganea; Rosa P. Gomariz

J Immunol (1999) 162 (4): 2358–2367.

Abstract

View articletitled, Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Inhibit Endotoxin-Induced TNF-α Production by Macrophages: In Vitro and In Vivo Studies<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lysophosphatidic Acid and Sphingosine 1-Phosphate Protection of T Cells from Apoptosis in Association with Suppression of Bax ¹

Edward J. Goetzl; Yvonne Kong; Baisong Mei

J Immunol (1999) 162 (4): 2049–2056.

Abstract

View articletitled, Lysophosphatidic Acid and Sphingosine 1-Phosphate Protection of T Cells from Apoptosis in Association with Suppression of Bax<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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“Allergen Engineering”: Variants of the Timothy Grass Pollen Allergen Phl p 5b with Reduced IgE-Binding Capacity but Conserved T Cell Reactivity ¹

Gabriele Schramm; Helga Kahlert; Roland Suck; Bernhard Weber; Hans-Thomas Stüwe; Wolf-Dieter Müller; Albrecht Bufe; Wolf-Meinhard Becker; Max W. Schlaak; Lothar Jäger; Oliver Cromwell; Helmut Fiebig

J Immunol (1999) 162 (4): 2406–2414.

Abstract

View articletitled, “Allergen Engineering”: Variants of the Timothy Grass Pollen Allergen Phl p 5b with Reduced IgE-Binding Capacity but Conserved T Cell Reactivity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Airway Inflammation by Passive Transfer of Allergen-Specific Th1 and Th2 Cells in a Mouse Model of Asthma ¹

David A. Randolph; Cynthia J. L. Carruthers; Susanne J. Szabo; Kenneth M. Murphy; David D. Chaplin

J Immunol (1999) 162 (4): 2375–2383.

Abstract

View articletitled, Modulation of Airway Inflammation by Passive Transfer of Allergen-Specific Th1 and Th2 Cells in a Mouse Model of Asthma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dual MHC Class I and Class II Restriction of a Single T Cell Receptor: Distinct Modes of Tolerance Induction by Two Classes of Autoantigens ¹

Ivica Arsov; Stanislav Vukmanović

J Immunol (1999) 162 (4): 2008–2015.

Abstract

View articletitled, Dual MHC Class I and Class II Restriction of a Single T Cell Receptor: Distinct Modes of Tolerance Induction by Two Classes of Autoantigens<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of Actin Microfilaments in the Down-Regulation of the Degranulation Response in RBL-2H3 Mast Cells ¹

Luciano Frigeri; John R. Apgar

J Immunol (1999) 162 (4): 2243–2250.

Abstract

View articletitled, The Role of Actin Microfilaments in the Down-Regulation of the Degranulation Response in RBL-2H3 Mast Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of CD80, CD86, and CTLA4 in Alloimmune Responses and the Induction of Long-Term Allograft Survival ¹

Thomas A. Judge; Zihou Wu; Xiang-Guang Zheng; Arlene H. Sharpe; Mohamed H. Sayegh; Laurence A. Turka

J Immunol (1999) 162 (4): 1947–1951.

Abstract

View articletitled, The Role of CD80, CD86, and CTLA4 in Alloimmune Responses and the Induction of Long-Term Allograft Survival<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Direct Delivery of the Bordetella pertussis Adenylate Cyclase Toxin to the MHC Class I Antigen Presentation Pathway ¹

Pierre Guermonprez; Daniel Ladant; Gouzel Karimova; Agnes Ullmann; Claude Leclerc

J Immunol (1999) 162 (4): 1910–1916.

Abstract

View articletitled, Direct Delivery of the Bordetella pertussis Adenylate Cyclase Toxin to the MHC Class I Antigen Presentation Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of the IL-12 Receptor β1 and β2 Subunits in Human Tuberculosis ¹

Ming Zhang; Jianhua Gong; David H. Presky; Wanfen Xue; Peter F. Barnes

J Immunol (1999) 162 (4): 2441–2447.

Abstract

View articletitled, Expression of the IL-12 Receptor β1 and β2 Subunits in Human Tuberculosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells ¹

Thaddeus C. George; Llewellyn H. Mason; John R. Ortaldo; Vinay Kumar; Michael Bennett

J Immunol (1999) 162 (4): 2035–2043.

Abstract

View articletitled, Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Conformation-Dependent Epitope in Addison’s Disease and Other Endocrinological Autoimmune Diseases Maps to a Carboxyl-Terminal Functional Domain of Human Steroid 21-Hydroxylase ¹

Andrej Nikoshkov; Alberto Falorni; Svetlana Lajic; Stefano Laureti; Anna Wedell; Åke Lernmark; Holger Luthman

J Immunol (1999) 162 (4): 2422–2426.

Abstract

View articletitled, A Conformation-Dependent Epitope in Addison’s Disease and Other Endocrinological Autoimmune Diseases Maps to a Carboxyl-Terminal Functional Domain of Human Steroid 21-Hydroxylase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Effector Memory T Cells Express CD86: A Functional Role in Naive T Cell Priming

Pascale Jeannin; Nathalie Herbault; Yves Delneste; Giovanni Magistrelli; Sybille Lecoanet-Henchoz; Gersende Caron; Jean-Pierre Aubry; Jean-Yves Bonnefoy

J Immunol (1999) 162 (4): 2044–2048.

Abstract

View articletitled, Human Effector Memory T Cells Express CD86: A Functional Role in Naive T Cell Priming

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Mitogenic Activity of Purified Capsular Polysaccharide A from Bacteroides fragilis: Differential Stimulatory Effect on Mouse and Rat Lymphocytes In Vitro ¹

Jeffery O. Brubaker; Qiao Li; Arthur O. Tzianabos; Dennis L. Kasper; Robert W. Finberg

J Immunol (1999) 162 (4): 2235–2242.

Abstract

View articletitled, Mitogenic Activity of Purified Capsular Polysaccharide A from Bacteroides fragilis: Differential Stimulatory Effect on Mouse and Rat Lymphocytes In Vitro<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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β₁ Integrin Cross-Linking Inhibits CD16-Induced Phospholipase D and Secretory Phospholipase A₂ Activity and Granule Exocytosis in Human NK cells: Role of Phospholipase D in CD16-Triggered Degranulation ¹

Michele Milella; Angela Gismondi; Paola Roncaioli; Gabriella Palmieri; Stefania Morrone; Mario Piccoli; Luigi Frati; Maria Grazia Cifone; Angela Santoni

J Immunol (1999) 162 (4): 2064–2072.

Abstract

View articletitled, β1 Integrin Cross-Linking Inhibits CD16-Induced Phospholipase D and Secretory Phospholipase A2 Activity and Granule Exocytosis in Human NK cells: Role of Phospholipase D in CD16-Triggered Degranulation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Molecular Mechanisms and Selection Influence the Generation of the Human VλJλ Repertoire ¹

Nancy L. Farner; Thomas Dörner; Peter E. Lipsky

J Immunol (1999) 162 (4): 2137–2145.

Abstract

View articletitled, Molecular Mechanisms and Selection Influence the Generation of the Human VλJλ Repertoire<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis ¹

C. James Cummings; Thomas R. Martin; Charles W. Frevert; Joanne M. Quan; Venus A. Wong; Steven M. Mongovin; Tonja R. Hagen; Kenneth P. Steinberg; Richard B. Goodman

J Immunol (1999) 162 (4): 2341–2346.

Abstract

View articletitled, Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunostimulatory CpG-Oligodeoxynucleotides Cause Extramedullary Murine Hemopoiesis ¹

Tim Sparwasser; Lothar Hültner; Eva Sophie Koch; Arne Luz; Grayson B. Lipford; Hermann Wagner

J Immunol (1999) 162 (4): 2368–2374.

Abstract

View articletitled, Immunostimulatory CpG-Oligodeoxynucleotides Cause Extramedullary Murine Hemopoiesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mycobacterium bovis Bacille Calmette-Guérin Enhances Pathogenicity of Simian Immunodeficiency Virus Infection and Accelerates Progression to AIDS in Macaques: A Role of Persistent T cell Activation in AIDS Pathogenesis ¹

Dejiang Zhou; Yun Shen; Laura Chalifoux; David Lee-Parritz; Meredith Simon; Prabhat K. Sehgal; Leiya Zheng; Matilda Halloran; Zheng W. Chen

J Immunol (1999) 162 (4): 2204–2216.

Abstract

View articletitled, Mycobacterium bovis Bacille Calmette-Guérin Enhances Pathogenicity of Simian Immunodeficiency Virus Infection and Accelerates Progression to AIDS in Macaques: A Role of Persistent T cell Activation in AIDS Pathogenesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Specific CD3ε Association of a Phosphodiesterase 4B Isoform Determines Its Selective Tyrosine Phosphorylation After CD3 Ligation ¹

Miren L. Baroja; Lenora B. Cieslinski; Theodore J. Torphy; Ronald L. Wange; Joaquín Madrenas

J Immunol (1999) 162 (4): 2016–2023.

Abstract

View articletitled, Specific CD3ε Association of a Phosphodiesterase 4B Isoform Determines Its Selective Tyrosine Phosphorylation After CD3 Ligation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Signal Transduction Pathways Involved in the Activation of NF-κB, AP-1, and c-fos by Mycoplasma fermentans Membrane Lipoproteins in Macrophages ¹

Georges Rawadi; Josefina Garcia; Brigitte Lemercier; Sergio Roman-Roman

J Immunol (1999) 162 (4): 2193–2203.

Abstract

View articletitled, Signal Transduction Pathways Involved in the Activation of NF-κB, AP-1, and c-fos by Mycoplasma fermentans Membrane Lipoproteins in Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: The CD45 Tyrosine Phosphatase Is an Inhibitor of Lck Activity in Thymocytes

Ugo D’Oro; Jonathan D. Ashwell

J Immunol (1999) 162 (4): 1879–1883.

Abstract

View articletitled, Cutting Edge: The CD45 Tyrosine Phosphatase Is an Inhibitor of Lck Activity in Thymocytes

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Conserved CTL Epitopes Shared Between HIV-Infected Human Long-Term Survivors and Chimpanzees ¹

Sunita S. Balla-Jhagjhoorsingh; Gerrit Koopman; Petra Mooij; Tom G. M. Haaksma; Vera J. P. Teeuwsen; Ronald E. Bontrop; Jonathan L. Heeney

J Immunol (1999) 162 (4): 2308–2314.

Abstract

View articletitled, Conserved CTL Epitopes Shared Between HIV-Infected Human Long-Term Survivors and Chimpanzees<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fas Ligand and Fas Are Expressed Constitutively in Human Astrocytes and the Expression Increases with IL-1, IL-6, TNF-α, or IFN-γ

Chulhee Choi; Joo Young Park; Jeonggi Lee; Jung-Hee Lim; Eui-Cheol Shin; Young Soo Ahn; Chul-Hoon Kim; Se-Jong Kim; Joo-Deuk Kim; Il Saing Choi; In-Hong Choi

J Immunol (1999) 162 (4): 1889–1895.

Abstract

View articletitled, Fas Ligand and Fas Are Expressed Constitutively in Human Astrocytes and the Expression Increases with IL-1, IL-6, TNF-α, or IFN-γ

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The p65 Subunit of NF-κB Is Redundant with p50 During B Cell Proliferative Responses, and Is Required for Germline C_H Transcription and Class Switching to IgG3 ¹

Bruce H. Horwitz; Piotr Zelazowski; Yi Shen; Karen M. Wolcott; Martin L. Scott; David Baltimore; Clifford M. Snapper

J Immunol (1999) 162 (4): 1941–1946.

Abstract

View articletitled, The p65 Subunit of NF-κB Is Redundant with p50 During B Cell Proliferative Responses, and Is Required for Germline CH Transcription and Class Switching to IgG3<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD38-Mediated Signaling Events in Murine Pro-B Cells Expressing Human CD38 With or Without Its Cytoplasmic Domain ¹

Akira Kitanaka; Toshio Suzuki; Chikako Ito; Hikari Nishigaki; Elaine Coustan-Smith; Terukazu Tanaka; Yoshitsugu Kubota; Dario Campana

J Immunol (1999) 162 (4): 1952–1958.

Abstract

View articletitled, CD38-Mediated Signaling Events in Murine Pro-B Cells Expressing Human CD38 With or Without Its Cytoplasmic Domain<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Calcium-Dependent Activation of TNF Family Gene Expression by Ca²⁺/Calmodulin Kinase Type IV/Gr and Calcineurin ¹

Francis M. Lobo; Reza Zanjani; Nga Ho; Talal A. Chatila; Ramsay L. Fuleihan

J Immunol (1999) 162 (4): 2057–2063.

Abstract

View articletitled, Calcium-Dependent Activation of TNF Family Gene Expression by Ca2+/Calmodulin Kinase Type IV/Gr and Calcineurin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cross-Linking of CD44 on Rheumatoid Synovial Cells Up-Regulates VCAM-1 ¹

Koichi Fujii; Yoshiya Tanaka; Stefan Hubscher; Kazuyoshi Saito; Toshiyuki Ota; Sumiya Eto

J Immunol (1999) 162 (4): 2391–2398.

Abstract

View articletitled, Cross-Linking of CD44 on Rheumatoid Synovial Cells Up-Regulates VCAM-1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Intranasally Induced Immunological Tolerance Is Determined by Characteristics of the Draining Lymph Nodes: Studies with OVA and Human Cartilage gp-39

Danielle A. W. Wolvers; Christina J. J. Coenen-de Roo; Reina E. Mebius; Maarten J. F. van der Cammen; Felicia Tirion; André M. M. Miltenburg; Georg Kraal

J Immunol (1999) 162 (4): 1994–1998.

Abstract

View articletitled, Intranasally Induced Immunological Tolerance Is Determined by Characteristics of the Draining Lymph Nodes: Studies with OVA and Human Cartilage gp-39

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Genetic Dissection of SLE Pathogenesis: Adoptive Transfer of Sle1 Mediates the Loss of Tolerance by Bone Marrow-Derived B Cells ¹

Eric S. Sobel; Chandra Mohan; Laurence Morel; Joel Schiffenbauer; Edward K. Wakeland

J Immunol (1999) 162 (4): 2415–2421.

Abstract

View articletitled, Genetic Dissection of SLE Pathogenesis: Adoptive Transfer of Sle1 Mediates the Loss of Tolerance by Bone Marrow-Derived B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Expression of Receptors for Calcitonin Gene-Related Peptide, Calcitonin, and Vasoactive Intestinal Peptide in the Human Thymus and Thymomas from Myasthenia Gravis Patients ¹

J.-C. Marie; A. Wakkach; A.-M. Coudray; E. Chastre; S. Berrih-Aknin; C. Gespach

J Immunol (1999) 162 (4): 2103–2112.

Abstract

View articletitled, Functional Expression of Receptors for Calcitonin Gene-Related Peptide, Calcitonin, and Vasoactive Intestinal Peptide in the Human Thymus and Thymomas from Myasthenia Gravis Patients<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phosphorylation of Cytosolic Phospholipase A₂ and the Release of Arachidonic Acid in Human Neutrophils ¹

Sergei I. Syrbu; Waltraut H. Waterman; Thaddeus F. P. Molski; Deepa Nagarkatti; Jean-Jacques Hajjar; Ramadan I. Sha’afi

J Immunol (1999) 162 (4): 2334–2340.

Abstract

View articletitled, Phosphorylation of Cytosolic Phospholipase A2 and the Release of Arachidonic Acid in Human Neutrophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Tyrosine Phosphorylation Sites in the CD28 Cytoplasmic Domain and Their Role in the Costimulation of Jurkat T Cells ¹

Ali Sadra; Tomas Cinek; Jerry L. Arellano; Jia Shi; Kenneth E. Truitt; John B. Imboden

J Immunol (1999) 162 (4): 1966–1973.

Abstract

View articletitled, Identification of Tyrosine Phosphorylation Sites in the CD28 Cytoplasmic Domain and Their Role in the Costimulation of Jurkat T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fas Ligand Induction in Human NK Cells Is Regulated by Redox Through a Calcineurin-Nuclear Factors of Activated T Cell-Dependent Pathway

Keizo Furuke; Mitsuhiro Shiraishi; Howard S. Mostowski; Eda T. Bloom

J Immunol (1999) 162 (4): 1988–1993.

Abstract

View articletitled, Fas Ligand Induction in Human NK Cells Is Regulated by Redox Through a Calcineurin-Nuclear Factors of Activated T Cell-Dependent Pathway

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IFN-γ-Mediated Control of Coxiella burnetii Survival in Monocytes: The Role of Cell Apoptosis and TNF ¹

Jérôme Dellacasagrande; Christian Capo; Didier Raoult; Jean-Louis Mege

J Immunol (1999) 162 (4): 2259–2265.

Abstract

View articletitled, IFN-γ-Mediated Control of Coxiella burnetii Survival in Monocytes: The Role of Cell Apoptosis and TNF<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Residues in the First Domain of Human Fcα Receptor Essential for Interaction with IgA ¹

Bruce D. Wines; Mark D. Hulett; Gary P. Jamieson; Halina M. Trist; Joanne M. Spratt; P. Mark Hogarth

J Immunol (1999) 162 (4): 2146–2153.

Abstract

View articletitled, Identification of Residues in the First Domain of Human Fcα Receptor Essential for Interaction with IgA<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN-γ-Producing CD4⁺ T Cells That Respond to Bacterial Antigens ¹

Stefan Wirtz; Susetta Finotto; Stephan Kanzler; Ansgar W. Lohse; Manfred Blessing; Hans A. Lehr; Peter R. Galle; Markus F. Neurath

J Immunol (1999) 162 (4): 1884–1888.

Abstract

View articletitled, Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN-γ-Producing CD4+ T Cells That Respond to Bacterial Antigens<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Extracellular HIV-1 Tat Protein Up-Regulates the Expression of Surface CXC-Chemokine Receptor 4 in Resting CD4⁺ T Cells ¹

Paola Secchiero; Davide Zella; Silvano Capitani; Robert C. Gallo; Giorgio Zauli

J Immunol (1999) 162 (4): 2427–2431.

Abstract

View articletitled, Extracellular HIV-1 Tat Protein Up-Regulates the Expression of Surface CXC-Chemokine Receptor 4 in Resting CD4+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Bacterial DNA Containing CpG Motifs Stimulates Lymphocyte-Dependent Protection of Mice Against Lethal Infection with Intracellular Bacteria ¹

Karen L. Elkins; Tonya R. Rhinehart-Jones; Scott Stibitz; Jacqueline S. Conover; Dennis M. Klinman

J Immunol (1999) 162 (4): 2291–2298.

Abstract

View articletitled, Bacterial DNA Containing CpG Motifs Stimulates Lymphocyte-Dependent Protection of Mice Against Lethal Infection with Intracellular Bacteria<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Effects of IL-2 and IL-15 on the Death and Survival of Activated TCRγδ⁺ Intestinal Intraepithelial Lymphocytes ¹

Ching-Liang Chu; Shih-Shun Chen; Tzong-Shoon Wu; Szu-Cheng Kuo; Nan-Shih Liao

J Immunol (1999) 162 (4): 1896–1903.

Abstract

View articletitled, Differential Effects of IL-2 and IL-15 on the Death and Survival of Activated TCRγδ+ Intestinal Intraepithelial Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lymphotactin Acts as an Innate Mucosal Adjuvant ¹

James W. Lillard, Jr.; Prosper N. Boyaka; Joseph A. Hedrick; Albert Zlotnik; Jerry R. McGhee

J Immunol (1999) 162 (4): 1959–1965.

Abstract

View articletitled, Lymphotactin Acts as an Innate Mucosal Adjuvant<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Use of Antagonist Peptides to Inhibit In Vitro T Cell Responses to Par j1, the Major Allergen of Parietaria judaica Pollen ¹

Raffaele De Palma; Shenhong Wu; Federica Sallusto; Gabriella Di Felice; Paola Martucci; Domenico Geraci; Paolo Colombo; Costantino Troise; Guido Sacerdoti; Arcangelo Nocera; Jack Gorski

J Immunol (1999) 162 (4): 1982–1987.

Abstract

View articletitled, Use of Antagonist Peptides to Inhibit In Vitro T Cell Responses to Par j1, the Major Allergen of Parietaria judaica Pollen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vitro and In Vivo Dependency of Chemokine Generation on C5a and TNF-α ¹

Boris J. Czermak; Vidya Sarma; Nicolas M. Bless; Hagen Schmal; Hans Peter Friedl; Peter A. Ward

J Immunol (1999) 162 (4): 2321–2325.

Abstract

View articletitled, In Vitro and In Vivo Dependency of Chemokine Generation on C5a and TNF-α<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD40 Activation Boosts T Cell Immunity In Vivo by Enhancing T Cell Clonal Expansion and Delaying Peripheral T Cell Deletion ¹

Joseph R. Maxwell; Jeff D. Campbell; Carol H. Kim; Anthony T. Vella

J Immunol (1999) 162 (4): 2024–2034.

Abstract

View articletitled, CD40 Activation Boosts T Cell Immunity In Vivo by Enhancing T Cell Clonal Expansion and Delaying Peripheral T Cell Deletion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Extensive Junctional Diversity in Ig Light Chain Genes from Early B Cell Progenitors of μMT Mice ¹

Laurent A. Bentolila; Stacy Olson; Aaron Marshall; François Rougeon; Christopher J. Paige; Noëlle Doyen; Gillian E. Wu

J Immunol (1999) 162 (4): 2123–2128.

Abstract

View articletitled, Extensive Junctional Diversity in Ig Light Chain Genes from Early B Cell Progenitors of μMT Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Characterization of the Somatic Hypermutation Process Leading to Antibody D1.3, a High Affinity Antibody Directed Against Lysozyme

Patrick England; Roland Nageotte; Martial Renard; Anne-Laure Page; Hugues Bedouelle

J Immunol (1999) 162 (4): 2129–2136.

Abstract

View articletitled, Functional Characterization of the Somatic Hypermutation Process Leading to Antibody D1.3, a High Affinity Antibody Directed Against Lysozyme

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Regulation of Cell Survival During B Lymphopoiesis: Apoptosis and Bcl-2/Bax Content of Precursor B Cells in Bone Marrow of Mice with Altered Expression of IL-7 and Recombinase-Activating Gene-2 ¹

Liwei Lu; Prosanto Chaudhury; Dennis G. Osmond

J Immunol (1999) 162 (4): 1931–1940.

Abstract

View articletitled, Regulation of Cell Survival During B Lymphopoiesis: Apoptosis and Bcl-2/Bax Content of Precursor B Cells in Bone Marrow of Mice with Altered Expression of IL-7 and Recombinase-Activating Gene-2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fcγ Receptor-Mediated Activation of Phospholipase D Regulates Macrophage Phagocytosis of IgG-Opsonized Particles ¹

David J. Kusner; Clifton F. Hall; Stephen Jackson

J Immunol (1999) 162 (4): 2266–2274.

Abstract

View articletitled, Fcγ Receptor-Mediated Activation of Phospholipase D Regulates Macrophage Phagocytosis of IgG-Opsonized Particles<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TCR-Independent Pathways Mediate the Effects of Antigen Dose and Altered Peptide Ligands on Th Cell Polarization ¹

Arash Grakoui; David L. Donermeyer; Osami Kanagawa; Kenneth M. Murphy; Paul M. Allen

J Immunol (1999) 162 (4): 1923–1930.

Abstract

View articletitled, TCR-Independent Pathways Mediate the Effects of Antigen Dose and Altered Peptide Ligands on Th Cell Polarization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Orientation and Nature of the Interaction Between Beef Insulin-Specific TCRs and the Insulin/Class II MHC Complex ¹

Joan E. Wither; Brian Vukusic

J Immunol (1999) 162 (4): 2113–2122.

Abstract

View articletitled, The Orientation and Nature of the Interaction Between Beef Insulin-Specific TCRs and the Insulin/Class II MHC Complex<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Neutrophil Recruitment by Human IL-17 Via C-X-C Chemokine Release in the Airways ¹

Martti Laan; Zhi-Hua Cui; Hiroshi Hoshino; Jan Lötvall; Margareta Sjöstrand; Dieter C. Gruenert; Bengt-Eric Skoogh; Anders Lindén

J Immunol (1999) 162 (4): 2347–2352.

Abstract

View articletitled, Neutrophil Recruitment by Human IL-17 Via C-X-C Chemokine Release in the Airways<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Isolation of High Avidity Melanoma-Reactive CTL from Heterogeneous Populations Using Peptide-MHC Tetramers ¹

Cassian Yee; Peter A. Savage; Peter P. Lee; Mark M. Davis; Philip D. Greenberg

J Immunol (1999) 162 (4): 2227–2234.

Abstract

View articletitled, Isolation of High Avidity Melanoma-Reactive CTL from Heterogeneous Populations Using Peptide-MHC Tetramers<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-α 2B Enhances Th1 Cytokine Responses in Bladder Cancer Patients Receiving Mycobacterium bovis Bacillus Calmette-Guérin Immunotherapy ¹

Yi Luo; Xiaohong Chen; Tracy M. Downs; William C. DeWolf; Michael A. O’Donnell

J Immunol (1999) 162 (4): 2399–2405.

Abstract

View articletitled, IFN-α 2B Enhances Th1 Cytokine Responses in Bladder Cancer Patients Receiving Mycobacterium bovis Bacillus Calmette-Guérin Immunotherapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Genome-Wide Search Identifies Two Susceptibility Loci for Experimental Autoimmune Encephalomyelitis on Rat Chromosomes 4 and 10 ¹

Marie-Paule Roth; Carine Viratelle; Laurence Dolbois; Maxence Delverdier; Nicolas Borot; Lucette Pelletier; Philippe Druet; Michel Clanet; Hélène Coppin

J Immunol (1999) 162 (4): 1917–1922.

Abstract

View articletitled, A Genome-Wide Search Identifies Two Susceptibility Loci for Experimental Autoimmune Encephalomyelitis on Rat Chromosomes 4 and 10<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The β-Glucan-Binding Lectin Site of Mouse CR3 (CD11b/CD18) and Its Function in Generating a Primed State of the Receptor That Mediates Cytotoxic Activation in Response to iC3b-Opsonized Target Cells ¹

Yu Xia; Václav Větvička; Jun Yan; Margareta Hanikýřová; Tanya Mayadas; Gordon D. Ross

J Immunol (1999) 162 (4): 2281–2290.

Abstract

View articletitled, The β-Glucan-Binding Lectin Site of Mouse CR3 (CD11b/CD18) and Its Function in Generating a Primed State of the Receptor That Mediates Cytotoxic Activation in Response to iC3b-Opsonized Target Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-2, But Not IL-4 and Other Cytokines, Induces Phosphorylation of a 98-kDa Protein Associated with SHP-2, Phosphatidylinositol 3′-Kinase, and Grb2

Massimo Gadina; Chitra Sudarshan; John J. O’Shea

J Immunol (1999) 162 (4): 2081–2086.

Abstract

View articletitled, IL-2, But Not IL-4 and Other Cytokines, Induces Phosphorylation of a 98-kDa Protein Associated with SHP-2, Phosphatidylinositol 3′-Kinase, and Grb2

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Serial TCR Engagement and Down-Modulation by Peptide:MHC Molecule Ligands: Relationship to the Quality of Individual TCR Signaling Events

Yasushi Itoh; Bernhard Hemmer; Roland Martin; Ronald N. Germain

J Immunol (1999) 162 (4): 2073–2080.

Abstract

View articletitled, Serial TCR Engagement and Down-Modulation by Peptide:MHC Molecule Ligands: Relationship to the Quality of Individual TCR Signaling Events

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