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CUTTING EDGE

Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene ¹

Naomi Kuwata; Hideya Igarashi; Takafumi Ohmura; Shinichi Aizawa; Nobuo Sakaguchi

J Immunol (1999) 163 (12): 6355–6359.

Abstract

View articletitled, Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: The HLA-A0101-Restricted HY Minor Histocompatibility Antigen Originates from DFFRY* and Contains a Cysteinylated Cysteine Residue as Identified by a Novel Mass Spectrometric Technique ¹

Richard A. Pierce; Erin D. Field; Joke M. M. den Haan; Jennifer A. Caldwell; Forest M. White; Jarrod A. Marto; Wei Wang; Leslie M. Frost; Els Blokland; Carla Reinhardus; Jeffrey Shabanowitz; Donald F. Hunt; Els Goulmy; Victor H. Engelhard

J Immunol (1999) 163 (12): 6360–6364.

Abstract

View articletitled, Cutting Edge: The HLA-A*0101-Restricted HY Minor Histocompatibility Antigen Originates from DFFRY and Contains a Cysteinylated Cysteine Residue as Identified by a Novel Mass Spectrometric Technique<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Targeting of Human Dendritic Cells by Autologous NK Cells ¹

Julia L. Wilson; Lena C. Heffler; Jehad Charo; Annika Scheynius; Maria-Teresa Bejarano; Hans-Gustaf Ljunggren

J Immunol (1999) 163 (12): 6365–6370.

Abstract

View articletitled, Targeting of Human Dendritic Cells by Autologous NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of Paired Ig-Like Receptors in Rats ¹ ^²

Glynn Dennis, Jr.; Robert P. Stephan; Hiromi Kubagawa; Max D. Cooper

J Immunol (1999) 163 (12): 6371–6377.

Abstract

View articletitled, Characterization of Paired Ig-Like Receptors in Rats<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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IL-2 Plasmid Therapy of Murine Ovarian Carcinoma Inhibits the Growth of Tumor Ascites and Alters Its Cytokine Profile

Holly M. Horton; Oliver Dorigo; Pepe Hernandez; Deborah Anderson; Jonathan S. Berek; Suezanne E. Parker

J Immunol (1999) 163 (12): 6378–6385.

Abstract

View articletitled, IL-2 Plasmid Therapy of Murine Ovarian Carcinoma Inhibits the Growth of Tumor Ascites and Alters Its Cytokine Profile

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T Suppressor Lymphocytes Inhibit NF-κB-Mediated Transcription of CD86 Gene in APC ¹

Jianfeng Li; Zhuoru Liu; Shuiping Jiang; Raffaello Cortesini; Seth Lederman; Nicole Suciu-Foca

J Immunol (1999) 163 (12): 6386–6392.

Abstract

View articletitled, T Suppressor Lymphocytes Inhibit NF-κB-Mediated Transcription of CD86 Gene in APC<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Th1 and Th2 Deviation of Myelin-Autoreactive T Cells by Altered Peptide Ligands Is Associated with Reciprocal Regulation of Lck, Fyn, and ZAP-70 ¹

Rana A. K. Singh; Ying C. Q. Zang; Anju Shrivastava; Jian Hong; George T. Wang; Sufang Li; Maria V. Tejada-Simon; Milena Kozovska; Victor M. Rivera; Jingwu Z. Zhang

J Immunol (1999) 163 (12): 6393–6402.

Abstract

View articletitled, Th1 and Th2 Deviation of Myelin-Autoreactive T Cells by Altered Peptide Ligands Is Associated with Reciprocal Regulation of Lck, Fyn, and ZAP-70<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Extracellular Signal-Related Kinase (ERK) and p38 Mitogen-Activated Protein (MAP) Kinases Differentially Regulate the Lipopolysaccharide-Mediated Induction of Inducible Nitric Oxide Synthase and IL-12 in Macrophages: Leishmania Phosphoglycans Subvert Macrophage IL-12 Production by Targeting ERK MAP Kinase ¹

Gui-Jie Feng; Helen S. Goodridge; Margaret M. Harnett; Xiao-Qing Wei; Andrei V. Nikolaev; Adrian P. Higson; Foo-Y. Liew

J Immunol (1999) 163 (12): 6403–6412.

Abstract

View articletitled, Extracellular Signal-Related Kinase (ERK) and p38 Mitogen-Activated Protein (MAP) Kinases Differentially Regulate the Lipopolysaccharide-Mediated Induction of Inducible Nitric Oxide Synthase and IL-12 in Macrophages: Leishmania Phosphoglycans Subvert Macrophage IL-12 Production by Targeting ERK MAP Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of APC in the Selection of Immunodominant T Cell Epitopes ¹

Chenglie Ma; Phyllis E. Whiteley; Patricia M. Cameron; Daniel C. Freed; Alison Pressey; Shiow-Ling Chen; Beth Garni-Wagner; Carol Fang; Dennis M. Zaller; Linda S. Wicker; Janice S. Blum

J Immunol (1999) 163 (12): 6413–6423.

Abstract

View articletitled, Role of APC in the Selection of Immunodominant T Cell Epitopes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunogenicity. I. Use of Peptide Libraries to Identify Epitopes That Activate Clonotypic CD4⁺ T Cells and Induce T Cell Responses to Native Peptide Ligands ¹

Darcy B. Wilson; Clemencia Pinilla; Dianne H. Wilson; Kim Schroder; César Boggiano; Valeria Judkowski; Jonathan Kaye; Bernhard Hemmer; Roland Martin; Richard A. Houghten

J Immunol (1999) 163 (12): 6424–6434.

Abstract

View articletitled, Immunogenicity. I. Use of Peptide Libraries to Identify Epitopes That Activate Clonotypic CD4+ T Cells and Induce T Cell Responses to Native Peptide Ligands<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulated Association Between the Tyrosine Kinase Emt/Itk/Tsk and Phospholipase-Cγ1 in Human T Lymphocytes ¹

Juan J. Perez-Villar; Steven B. Kanner

J Immunol (1999) 163 (12): 6435–6441.

Abstract

View articletitled, Regulated Association Between the Tyrosine Kinase Emt/Itk/Tsk and Phospholipase-Cγ1 in Human T Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Follicular Dendritic Cells Protect Malignant B Cells from Apoptosis Induced by Anti-Fas and Antineoplastic Agents ¹

Ying X. Schwarz; Ming-yan Yang; Dahui Qin; Jiuhua Wu; W. David Jarvis; Steven Grant; Gregory F. Burton; Andras K. Szakal; John G. Tew

J Immunol (1999) 163 (12): 6442–6447.

Abstract

View articletitled, Follicular Dendritic Cells Protect Malignant B Cells from Apoptosis Induced by Anti-Fas and Antineoplastic Agents<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling ¹

James M. Brewer; Margaret Conacher; Christopher A. Hunter; Markus Mohrs; Frank Brombacher; James Alexander

J Immunol (1999) 163 (12): 6448–6454.

Abstract

View articletitled, Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antigen-Induced Unresponsiveness Results in Altered T Cell Signaling ¹

Dianne B. McKay; Hanna Y. Irie; Georg Hollander; James L. M. F. Ferrara; Terry B. Strom; YongSheng Li; Steven J. Burakoff

J Immunol (1999) 163 (12): 6455–6461.

Abstract

View articletitled, Antigen-Induced Unresponsiveness Results in Altered T Cell Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The In Vivo Fate of APCs Displaying Minor H Antigen and/or MHC Differences Is Regulated by CTLs Specific for Immunodominant Class I-Associated Epitopes ¹

Véronique Loyer; Pierre Fontaine; Stéphane Pion; Francis Hétu; Denis-Claude Roy; Claude Perreault

J Immunol (1999) 163 (12): 6462–6467.

Abstract

View articletitled, The In Vivo Fate of APCs Displaying Minor H Antigen and/or MHC Differences Is Regulated by CTLs Specific for Immunodominant Class I-Associated Epitopes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Protein-Protein and DNA-Protein Interactions Affect the Activity of Lymphoid-Specific IFN Regulatory Factors ¹

David Meraro; Sharon Hashmueli; Belly Koren; Aviva Azriel; André Oumard; Sabine Kirchhoff; Hansjörg Hauser; Sujatha Nagulapalli; Michael L. Atchison; Ben-Zion Levi

J Immunol (1999) 163 (12): 6468–6478.

Abstract

View articletitled, Protein-Protein and DNA-Protein Interactions Affect the Activity of Lymphoid-Specific IFN Regulatory Factors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of Immunoregulatory Donor T Cells in Suppression of Graft-Versus-Host Disease Following Donor Leukocyte Infusion Therapy ¹

Bryon D. Johnson; Emily E. Becker; James L. LaBelle; Robert L. Truitt

J Immunol (1999) 163 (12): 6479–6487.

Abstract

View articletitled, Role of Immunoregulatory Donor T Cells in Suppression of Graft-Versus-Host Disease Following Donor Leukocyte Infusion Therapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ Production and Cytotoxicity of IL-2-Activated Murine NK Cells Are Differentially Regulated by MHC Class I Molecules ¹

Akira Kubota; Rebecca H. Lian; Stefan Lohwasser; Margarita Salcedo; Fumio Takei

J Immunol (1999) 163 (12): 6488–6493.

Abstract

View articletitled, IFN-γ Production and Cytotoxicity of IL-2-Activated Murine NK Cells Are Differentially Regulated by MHC Class I Molecules<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Negative Regulation of CD4 Lineage Development and Responses by CD5 ¹

Claudia Peña-Rossi; Linda A. Zuckerman; Julie Strong; Joanne Kwan; William Ferris; Susan Chan; Alexander Tarakhovsky; Albert D. Beyers; Nigel Killeen

J Immunol (1999) 163 (12): 6494–6501.

Abstract

View articletitled, Negative Regulation of CD4 Lineage Development and Responses by CD5<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MHC Class I-Restricted Cytotoxic Lymphocyte Responses Induced by Enterotoxin-Based Mucosal Adjuvants ¹

Cameron P. Simmons; Pietro Mastroeni; Ray Fowler; Marjan Ghaem-maghami; Nils Lycke; Mariagrazia Pizza; Rino Rappuoli; Gordon Dougan

J Immunol (1999) 163 (12): 6502–6510.

Abstract

View articletitled, MHC Class I-Restricted Cytotoxic Lymphocyte Responses Induced by Enterotoxin-Based Mucosal Adjuvants<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Tolerance to Maternal Immunoglobulins: Resilience of the Specific T Cell Repertoire in Spite of Long-Lasting Perturbations ¹

Mathias Faure; Sébastien Calbo; Jean Kanellopoulos; Anne-Marie Drapier; Pierre-André Cazenave; Dominique Rueff-Juy

J Immunol (1999) 163 (12): 6511–6519.

Abstract

View articletitled, Tolerance to Maternal Immunoglobulins: Resilience of the Specific T Cell Repertoire in Spite of Long-Lasting Perturbations<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Robust B Cell Immunity but Impaired T Cell Proliferation in the Absence of CD134 (OX40)¹

Susanne D. Pippig; Claudia Peña-Rossi; James Long; Wayne R. Godfrey; Deborah J. Fowell; Steven L. Reiner; Marian L. Birkeland; Richard M. Locksley; A. Neil Barclay; Nigel Killeen

J Immunol (1999) 163 (12): 6520–6529.

Abstract

View articletitled, Robust B Cell Immunity but Impaired T Cell Proliferation in the Absence of CD134 (OX40)<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Increased p27^Kip1 Cyclin-Dependent Kinase Inhibitor Gene Expression Following Anti-IgM Treatment Promotes Apoptosis of WEHI 231 B Cells ¹

Min Wu; Robert E. Bellas; Jian Shen; William Yang; Gail E. Sonenshein

J Immunol (1999) 163 (12): 6530–6535.

Abstract

View articletitled, Increased p27Kip1 Cyclin-Dependent Kinase Inhibitor Gene Expression Following Anti-IgM Treatment Promotes Apoptosis of WEHI 231 B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Stat6-Dependent and -Independent Pathways for IL-4 Production ¹

Mark H. Kaplan; Andrea L. Wurster; Stephen T. Smiley; Michael J. Grusby3

J Immunol (1999) 163 (12): 6536–6540.

Abstract

View articletitled, Stat6-Dependent and -Independent Pathways for IL-4 Production<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Bacterial/CpG DNA Down-Modulates Colony Stimulating Factor-1 Receptor Surface Expression on Murine Bone Marrow-Derived Macrophages with Concomitant Growth Arrest and Factor-Independent Survival ¹

David P. Sester; Shannon J. Beasley; Matthew J. Sweet; Lindsay F. Fowles; Stephen L. Cronau; Katryn J. Stacey; David A. Hume

J Immunol (1999) 163 (12): 6541–6550.

Abstract

View articletitled, Bacterial/CpG DNA Down-Modulates Colony Stimulating Factor-1 Receptor Surface Expression on Murine Bone Marrow-Derived Macrophages with Concomitant Growth Arrest and Factor-Independent Survival<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Central Nervous System-Targeted Expression of the Complement Inhibitor sCrry Prevents Experimental Allergic Encephalomyelitis ¹

Nathalie Davoust; Serge Nataf; Rachael Reiman; Michael V. Holers; Iain L. Campbell; Scott R. Barnum

J Immunol (1999) 163 (12): 6551–6556.

Abstract

View articletitled, Central Nervous System-Targeted Expression of the Complement Inhibitor sCrry Prevents Experimental Allergic Encephalomyelitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ability of a Nondepleting Anti-CD4 Antibody to Inhibit Th2 Responses and Allergic Lung Inflammation Is Independent of Coreceptor Function ¹

Li Li; Mary Crowley; Andrea Nguyen; David Lo

J Immunol (1999) 163 (12): 6557–6566.

Abstract

View articletitled, Ability of a Nondepleting Anti-CD4 Antibody to Inhibit Th2 Responses and Allergic Lung Inflammation Is Independent of Coreceptor Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Selective Pharmacologic Inhibition of Murine and Human IL-12-Dependent Th1 Differentiation and IL-12 Signaling ¹

Michael E. Coon; Michael Diegel; Natasha Leshinsky; Stephen J. Klaus

J Immunol (1999) 163 (12): 6567–6574.

Abstract

View articletitled, Selective Pharmacologic Inhibition of Murine and Human IL-12-Dependent Th1 Differentiation and IL-12 Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TNF and Lymphotoxin β Cooperate in the Maintenance of Secondary Lymphoid Tissue Microarchitecture But Not in the Development of Lymph Nodes ¹

Dmitry V. Kuprash23; Marat B. Alimzhanov2; Alexei V. Tumanov2; Arthur O. Anderson; Klaus Pfeffer; Sergei A. Nedospasov

J Immunol (1999) 163 (12): 6575–6580.

Abstract

View articletitled, TNF and Lymphotoxin β Cooperate in the Maintenance of Secondary Lymphoid Tissue Microarchitecture But Not in the Development of Lymph Nodes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distinct Activities of p52/NF-κB Required for Proper Secondary Lymphoid Organ Microarchitecture: Functions Enhanced by Bcl-3

Ljiljana Poljak; Louise Carlson; Kirk Cunningham; Marie H. Kosco-Vilbois; Ulrich Siebenlist

J Immunol (1999) 163 (12): 6581–6588.

Abstract

View articletitled, Distinct Activities of p52/NF-κB Required for Proper Secondary Lymphoid Organ Microarchitecture: Functions Enhanced by Bcl-3

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Distinct Subcellular Localization and Substrate Specificity of Extracellular Signal-Regulated Kinase in B Cells upon Stimulation with IgM and CD40 ¹

Yumiko Shirakata; Kumiko Ishii; Hideo Yagita; Ko Okumura; Masaru Taniguchi; Toshitada Takemori

J Immunol (1999) 163 (12): 6589–6597.

Abstract

View articletitled, Distinct Subcellular Localization and Substrate Specificity of Extracellular Signal-Regulated Kinase in B Cells upon Stimulation with IgM and CD40<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Commitment to the CD4 Lineage Mediated by Extracellular Signal-Related Kinase Mitogen-Activated Protein Kinase and Lck Signaling ¹

Leslie L. Sharp; Stephen M. Hedrick

J Immunol (1999) 163 (12): 6598–6605.

Abstract

View articletitled, Commitment to the CD4 Lineage Mediated by Extracellular Signal-Related Kinase Mitogen-Activated Protein Kinase and Lck Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Negative Regulation of Macrophage Activation in Response to IFN-γ and Lipopolysaccharide by the STK/RON Receptor Tyrosine Kinase ¹

Qing-Ping Liu; Kristy Fruit; Jennifer Ward; Pamela H. Correll

J Immunol (1999) 163 (12): 6606–6613.

Abstract

View articletitled, Negative Regulation of Macrophage Activation in Response to IFN-γ and Lipopolysaccharide by the STK/RON Receptor Tyrosine Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ligation of Microglial CD40 Results in p44/42 Mitogen-Activated Protein Kinase-Dependent TNF-α Production That Is Opposed by TGF-β1 and IL-10

Jun Tan; Terrence Town; Michael Saxe; Daniel Paris; Yajuan Wu; Michael Mullan

J Immunol (1999) 163 (12): 6614–6621.

Abstract

View articletitled, Ligation of Microglial CD40 Results in p44/42 Mitogen-Activated Protein Kinase-Dependent TNF-α Production That Is Opposed by TGF-β1 and IL-10

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Analysis of the Defect in IFN-γ Induction of MHC Class II Genes in G1B Cells: Identification of a Novel and Functionally Critical Leucine-Rich Motif (62-LYLYLQL-68) in the Regulatory Factor X 5 Transcription Factor ¹

W. June Brickey; Kenneth L. Wright; Xin-Sheng Zhu; Jenny P.-Y. Ting

J Immunol (1999) 163 (12): 6622–6630.

Abstract

View articletitled, Analysis of the Defect in IFN-γ Induction of MHC Class II Genes in G1B Cells: Identification of a Novel and Functionally Critical Leucine-Rich Motif (62-LYLYLQL-68) in the Regulatory Factor X 5 Transcription Factor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The −180 Site of the IL-2 Promoter Is the Target of CREB/CREM Binding in T Cell Anergy

Jonathan D. Powell; Cara G. Lerner; Gerald R. Ewoldt; Ronald H. Schwartz

J Immunol (1999) 163 (12): 6631–6639.

Abstract

View articletitled, The −180 Site of the IL-2 Promoter Is the Target of CREB/CREM Binding in T Cell Anergy

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T Cell Activation Up-Regulates the Expression of the Focal Adhesion Kinase Pyk2: Opposing Roles for the Activation of Protein Kinase C and the Increase in Intracellular Ca²⁺

Masahiro Tsuchida; Eric R. Manthei; Tausif Alam; Stuart J. Knechtle; Majed M. Hamawy

J Immunol (1999) 163 (12): 6640–6650.

Abstract

View articletitled, T Cell Activation Up-Regulates the Expression of the Focal Adhesion Kinase Pyk2: Opposing Roles for the Activation of Protein Kinase C and the Increase in Intracellular Ca2+

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Contributions of Leukemia Inhibitory Factor Receptor and Oncostatin M Receptor to Signal Transduction in Heterodimeric Complexes with Glycoprotein 130 ¹

Heike M. Hermanns; Simone Radtke; Claude Haan; Hildegard Schmitz-Van de Leur; Jan Tavernier; Peter C. Heinrich; Iris Behrmann

J Immunol (1999) 163 (12): 6651–6658.

Abstract

View articletitled, Contributions of Leukemia Inhibitory Factor Receptor and Oncostatin M Receptor to Signal Transduction in Heterodimeric Complexes with Glycoprotein 130<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activation and Targeting of Immunoglobulin Switch Recombination by Activities Induced by EBV Infection ¹

Ming-jie Li; Nancy Maizels

J Immunol (1999) 163 (12): 6659–6664.

Abstract

View articletitled, Activation and Targeting of Immunoglobulin Switch Recombination by Activities Induced by EBV Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Misfolding of HLA-B27 as a Result of Its B Pocket Suggests a Novel Mechanism for Its Role in Susceptibility to Spondyloarthropathies

John P. Mear; Kathy L. Schreiber; Christian Münz; Xiaoming Zhu; Stefan Stevanović; Hans-Georg Rammensee; Sarah L. Rowland-Jones; Robert A. Colbert

J Immunol (1999) 163 (12): 6665–6670.

Abstract

View articletitled, Misfolding of HLA-B27 as a Result of Its B Pocket Suggests a Novel Mechanism for Its Role in Susceptibility to Spondyloarthropathies

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Microphthalmic Mice Display a B Cell Deficiency Similar to that Seen for Mast and NK Cells ¹

Kirstin Roundy; Angela Kollhoff; E. J. Eichwald; Janis J. Weis; John H. Weis

J Immunol (1999) 163 (12): 6671–6678.

Abstract

View articletitled, Microphthalmic Mice Display a B Cell Deficiency Similar to that Seen for Mast and NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Membrane Topology and Dimerization of the Two Subunits of the Transporter Associated with Antigen Processing Reveal a Three-Domain Structure ¹

Jan C. Vos; Pieter Spee; Frank Momburg; Jacques Neefjes

J Immunol (1999) 163 (12): 6679–6685.

Abstract

View articletitled, Membrane Topology and Dimerization of the Two Subunits of the Transporter Associated with Antigen Processing Reveal a Three-Domain Structure<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Staphylococcal Enterotoxin H Displays Unique MHC Class II-Binding Properties

Helen Nilsson; Per Björk; Mikael Dohlsten; Per Antonsson

J Immunol (1999) 163 (12): 6686–6693.

Abstract

View articletitled, Staphylococcal Enterotoxin H Displays Unique MHC Class II-Binding Properties

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HOST DEFENSE

Mutational Analysis of Avidity and Fine Specificity of Anti-Levan Antibodies

Kurt Brorson; Cynthia Thompson; George Wei; Michael Krasnokutsky; Kathryn E. Stein

J Immunol (1999) 163 (12): 6694–6701.

Abstract

View articletitled, Mutational Analysis of Avidity and Fine Specificity of Anti-Levan Antibodies

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Kupffer Cells from Schistosoma mansoni-Infected Mice Participate in the Prompt Type 2 Differentiation of Hepatic T Cells in Response to Worm Antigens ¹

Nobuki Hayashi; Kiyoshi Matsui; Hiroko Tsutsui; Yoshio Osada; Raafat T. Mohamed; Hiroki Nakano; Shin-ichiro Kashiwamura; Yasuko Hyodo; Kiyoshi Takeda; Shizuo Akira; Toshikazu Hada; Kazuya Higashino; Somei Kojima; Kenji Nakanishi3

J Immunol (1999) 163 (12): 6702–6711.

Abstract

View articletitled, Kupffer Cells from Schistosoma mansoni-Infected Mice Participate in the Prompt Type 2 Differentiation of Hepatic T Cells in Response to Worm Antigens<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Th2 Responses and IgE Is Largely Due to Carbohydrates Functioning as Adjuvants on Schistosoma mansoni Egg Antigens ¹

Mitsuhiro Okano; Abhay R. Satoskar; Kazunori Nishizaki; Mie Abe; Donald A. Harn, Jr.

J Immunol (1999) 163 (12): 6712–6717.

Abstract

View articletitled, Induction of Th2 Responses and IgE Is Largely Due to Carbohydrates Functioning as Adjuvants on Schistosoma mansoni Egg Antigens<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression and Regulation of the Human β-Defensins hBD-1 and hBD-2 in Intestinal Epithelium ¹

Deborah A. O’Neil; Edith Martin Porter; Dirk Elewaut; G. Mark Anderson; Lars Eckmann; Tomas Ganz; Martin F. Kagnoff

J Immunol (1999) 163 (12): 6718–6724.

Abstract

View articletitled, Expression and Regulation of the Human β-Defensins hBD-1 and hBD-2 in Intestinal Epithelium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Reduced Ultraviolet-Induced Carcinogenesis in Mice with a Functional Disruption in B7-Mediated Costimulation ¹

Stefan Beissert; Jeffrey A. Bluestone; Iris Mindt; Maik Voskort; Dieter Metze; Annette Mehling; Thomas A. Luger; Thomas Schwarz; Stephan Grabbe

J Immunol (1999) 163 (12): 6725–6731.

Abstract

View articletitled, Reduced Ultraviolet-Induced Carcinogenesis in Mice with a Functional Disruption in B7-Mediated Costimulation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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NADPH Oxidase Activation and Assembly During Phagocytosis ¹

Frank R. DeLeo; Lee-Ann H. Allen; Michael Apicella; William M. Nauseef

J Immunol (1999) 163 (12): 6732–6740.

Abstract

View articletitled, NADPH Oxidase Activation and Assembly During Phagocytosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Adjacent Flanking Region Plays a Critical Role in Facilitating the Presentation of the Listeria monocytogenes Product lemA to H2 M3^wt-Restricted, Peptide-Specific Murine CD8 Cells

Roger J. Kurlander; Elizabeth Chao; Janet Fields; Chandrasekaran Nataraj

J Immunol (1999) 163 (12): 6741–6747.

Abstract

View articletitled, The Adjacent Flanking Region Plays a Critical Role in Facilitating the Presentation of the Listeria monocytogenes Product lemA to H2 M3wt-Restricted, Peptide-Specific Murine CD8 Cells

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The CD14 Ligands Lipoarabinomannan and Lipopolysaccharide Differ in Their Requirement for Toll-Like Receptors ¹

Terry K. Means; Egil Lien; Atsutoshi Yoshimura; Shuyan Wang; Douglas T. Golenbock; Matthew J. Fenton

J Immunol (1999) 163 (12): 6748–6755.

Abstract

View articletitled, The CD14 Ligands Lipoarabinomannan and Lipopolysaccharide Differ in Their Requirement for Toll-Like Receptors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A DNA Immunization Model Study with Constructs Expressing the Tick-Borne Encephalitis Virus Envelope Protein E in Different Physical Forms

Judith H. Aberle; Stephan W. Aberle; Steven L. Allison; Karin Stiasny; Michael Ecker; Christian W. Mandl; Rudolf Berger; Franz X. Heinz

J Immunol (1999) 163 (12): 6756–6761.

Abstract

View articletitled, A DNA Immunization Model Study with Constructs Expressing the Tick-Borne Encephalitis Virus Envelope Protein E in Different Physical Forms

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Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion ¹

Jose Engelmayer; Marie Larsson; Marion Subklewe; Ann Chahroudi; William I. Cox; Ralph M. Steinman; Nina Bhardwaj

J Immunol (1999) 163 (12): 6762–6768.

Abstract

View articletitled, Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Critical Role of CD28 in Protective Immunity Against Salmonella typhimurium

Hans-Willi Mittrücker; Anne Köhler; Tak W. Mak; Stefan H. E. Kaufmann

J Immunol (1999) 163 (12): 6769–6776.

Abstract

View articletitled, Critical Role of CD28 in Protective Immunity Against Salmonella typhimurium

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Utilization of Two Seven-Transmembrane, G Protein-Coupled Receptors, Formyl Peptide Receptor-Like 1 and Formyl Peptide Receptor, by the Synthetic Hexapeptide WKYMVm for Human Phagocyte Activation ¹

Yingying Le; Wanghua Gong; Baoqun Li; Nancy M. Dunlop; Weiping Shen; Shao Bo Su; Richard D. Ye; Ji Ming Wang

J Immunol (1999) 163 (12): 6777–6784.

Abstract

View articletitled, Utilization of Two Seven-Transmembrane, G Protein-Coupled Receptors, Formyl Peptide Receptor-Like 1 and Formyl Peptide Receptor, by the Synthetic Hexapeptide WKYMVm for Human Phagocyte Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Syk Activation Initiates Downstream Signaling Events During Human Polymorphonuclear Leukocyte Phagocytosis ¹

Evelin M. B. Raeder; Pamela J. Mansfield; Vania Hinkovska-Galcheva; James A. Shayman; Laurence A. Boxer

J Immunol (1999) 163 (12): 6785–6793.

Abstract

View articletitled, Syk Activation Initiates Downstream Signaling Events During Human Polymorphonuclear Leukocyte Phagocytosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Blockade of T Cell Costimulation by CTLA4-Ig Inhibits Lung Inflammation in Murine Hypersensitivity Pneumonitis ¹

Evelyne Israël-Assayag; Marcien Fournier; Yvon Cormier

J Immunol (1999) 163 (12): 6794–6799.

Abstract

View articletitled, Blockade of T Cell Costimulation by CTLA4-Ig Inhibits Lung Inflammation in Murine Hypersensitivity Pneumonitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Silymarin Suppresses TNF-Induced Activation of NF-κB, c-Jun N-Terminal Kinase, and Apoptosis ¹

Sunil K. Manna; Asok Mukhopadhyay; Nguyen T. Van; Bharat B. Aggarwal

J Immunol (1999) 163 (12): 6800–6809.

Abstract

View articletitled, Silymarin Suppresses TNF-Induced Activation of NF-κB, c-Jun N-Terminal Kinase, and Apoptosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Determination of the Contribution of Cysteinyl Leukotrienes and Leukotriene B₄ in Acute Inflammatory Responses Using 5-Lipoxygenase- and Leukotriene A₄ Hydrolase-Deficient Mice ¹

Robert S. Byrum; Jennifer L. Goulet; John N. Snouwaert; Richard J. Griffiths; Beverly H. Koller

J Immunol (1999) 163 (12): 6810–6819.

Abstract

View articletitled, Determination of the Contribution of Cysteinyl Leukotrienes and Leukotriene B4 in Acute Inflammatory Responses Using 5-Lipoxygenase- and Leukotriene A4 Hydrolase-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Protection Against the Mortality Associated with Disease Models Mediated by TNF and IFN-γ in Mice Lacking IFN Regulatory Factor-1

Giorgio Senaldi; Christine L. Shaklee; Jane Guo; Laura Martin; Thomas Boone; Tak W. Mak; Thomas R. Ulich

J Immunol (1999) 163 (12): 6820–6826.

Abstract

View articletitled, Protection Against the Mortality Associated with Disease Models Mediated by TNF and IFN-γ in Mice Lacking IFN Regulatory Factor-1

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NF-κB/Rel Transcription Factors: c-Rel Promotes Airway Hyperresponsiveness and Allergic Pulmonary Inflammation ¹

Carolyn E. Donovan; David A. Mark; Hong Zhen He; Hsiou-Chi Liou; Lester Kobzik; Yunsheng Wang; George T. De Sanctis; David L. Perkins; Patricia W. Finn

J Immunol (1999) 163 (12): 6827–6833.

Abstract

View articletitled, NF-κB/Rel Transcription Factors: c-Rel Promotes Airway Hyperresponsiveness and Allergic Pulmonary Inflammation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Development of Adenovirus Vectors Encoding Rat Complement Regulators for Use in Therapy in Rodent Models of Inflammatory Diseases ¹

Yvonne McGrath; Gavin W. G. Wilkinson; O. Brad Spiller; B. Paul Morgan

J Immunol (1999) 163 (12): 6834–6840.

Abstract

View articletitled, Development of Adenovirus Vectors Encoding Rat Complement Regulators for Use in Therapy in Rodent Models of Inflammatory Diseases<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Nitric Oxide Plays a Critical Role in the Recovery of Lewis Rats from Experimental Autoimmune Encephalomyelitis and the Maintenance of Resistance to Reinduction ¹

Nikki C. O’Brien; Brett Charlton; William B. Cowden; David O. Willenborg

J Immunol (1999) 163 (12): 6841–6847.

Abstract

View articletitled, Nitric Oxide Plays a Critical Role in the Recovery of Lewis Rats from Experimental Autoimmune Encephalomyelitis and the Maintenance of Resistance to Reinduction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Rat and Mouse Homologues of MASP-2 and MAp19, components of the Lectin Activation Pathway of Complement ¹ ^² ^³

Cordula M. Stover; Steffen Thiel; Nicholas J. Lynch; Wilhelm J. Schwaeble

J Immunol (1999) 163 (12): 6848–6859.

Abstract

View articletitled, The Rat and Mouse Homologues of MASP-2 and MAp19, components of the Lectin Activation Pathway of Complement<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a> <a href="javascript:;" reveal-id="FN3" data-open="FN3" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">3</a>

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Endothelial Cell E- and P-Selectin Up-Regulation in Murine Contact Sensitivity Is Prolonged by Distinct Mechanisms Occurring in Sequence ¹

Olivier A. Harari; Julie F. McHale; Diane Marshall; Saifur Ahmed; Derek Brown; Philip W. Askenase; Dorian O. Haskard

J Immunol (1999) 163 (12): 6860–6866.

Abstract

View articletitled, Endothelial Cell E- and P-Selectin Up-Regulation in Murine Contact Sensitivity Is Prolonged by Distinct Mechanisms Occurring in Sequence<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens

Udai S. Kammula; Kang-Hun Lee; Adam I Riker; Ena Wang; Galen A. Ohnmacht; Steven A. Rosenberg; Francesco M. Marincola

J Immunol (1999) 163 (12): 6867–6875.

Abstract

View articletitled, Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens

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Activation of Eotaxin Gene Transcription by NF-κB and STAT6 in Human Airway Epithelial Cells ¹

Satoshi Matsukura; Cristiana Stellato; James R. Plitt; Carol Bickel; Katsushi Miura; Steve N. Georas; Vincenzo Casolaro; Robert P. Schleimer

J Immunol (1999) 163 (12): 6876–6883.

Abstract

View articletitled, Activation of Eotaxin Gene Transcription by NF-κB and STAT6 in Human Airway Epithelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-12 Drives IFN-γ-Dependent Autoimmune Kidney Disease in MRL-Fas^lpr Mice ¹

A. Schwarting; G. Tesch; K. Kinoshita; R. Maron; H. L. Weiner; V. Rubin Kelley

J Immunol (1999) 163 (12): 6884–6891.

Abstract

View articletitled, IL-12 Drives IFN-γ-Dependent Autoimmune Kidney Disease in MRL-Faslpr Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vivo Administration of Recombinant IL-2 to Individuals Infected by HIV Down-Modulates the Binding and Expression of the Transcription Factors Ying-Yang-1 and Leader Binding Protein-1/Late Simian Virus 40 Factor ¹

Chiara Bovolenta; Laura Camorali; Alessandro L. Lorini; Giuliana Vallanti; Silvia Ghezzi; Giuseppe Tambussi; Adriano Lazzarin; Guido Poli

J Immunol (1999) 163 (12): 6892–6897.

Abstract

View articletitled, In Vivo Administration of Recombinant IL-2 to Individuals Infected by HIV Down-Modulates the Binding and Expression of the Transcription Factors Ying-Yang-1 and Leader Binding Protein-1/Late Simian Virus 40 Factor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antibody Repertoires of Four- and Five-Feature Translocus Mice Carrying Human Immunoglobulin Heavy Chain and κ and λ Light Chain Yeast Artificial Chromosomes ¹

Ian C. Nicholson; Xiangang Zou; Andrei V. Popov; Graham P. Cook; Elaine M. Corps; Sally Humphries; Christine Ayling; Beatriz Goyenechea; Jian Xian; Michael J. Taussig; Michael S. Neuberger; Marianne Brüggemann

J Immunol (1999) 163 (12): 6898–6906.

Abstract

View articletitled, Antibody Repertoires of Four- and Five-Feature Translocus Mice Carrying Human Immunoglobulin Heavy Chain and κ and λ Light Chain Yeast Artificial Chromosomes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Production of Soluble Granulocyte Colony-Stimulating Factor Receptors from Myelomonocytic Cells ¹

Hiromi Iwasaki; Kazuya Shimoda; Seiichi Okamura; Teruhisa Otsuka; Koji Nagafuji; Naoki Harada; Yuju Ohno; Toshihiro Miyamoto; Koichi Akashi; Mine Harada; Yoshiyuki Niho

J Immunol (1999) 163 (12): 6907–6911.

Abstract

View articletitled, Production of Soluble Granulocyte Colony-Stimulating Factor Receptors from Myelomonocytic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Loss of T Cell Signaling Molecules in Metastatic Melanoma Patients’ T Lymphocyte Subsets Expressing Distinct TCR Variable Regions ¹

Cristina Maccalli; Patrizia Pisarra; Claudia Vegetti; Marialuisa Sensi; Giorgio Parmiani; Andrea Anichini

J Immunol (1999) 163 (12): 6912–6923.

Abstract

View articletitled, Differential Loss of T Cell Signaling Molecules in Metastatic Melanoma Patients’ T Lymphocyte Subsets Expressing Distinct TCR Variable Regions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Monomeric Complement-Activating IgG Paraproteins ¹

Marten Trendelenburg; Christoph Hess; Mitsuko Kondo-Oestreicher; Jean D. Tissot; Peter Späth; Jürg A. Schifferli

J Immunol (1999) 163 (12): 6924–6932.

Abstract

View articletitled, Monomeric Complement-Activating IgG Paraproteins<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Persistent T Cell Anergy in Human Type 1 Diabetes ¹

H.-Michael Dosch; Roy K. Cheung; Wolfram Karges; Massimo Pietropaolo; Dorothy J. Becker

J Immunol (1999) 163 (12): 6933–6940.

Abstract

View articletitled, Persistent T Cell Anergy in Human Type 1 Diabetes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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