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CUTTING EDGE

Cutting Edge: Paradigm Revisited: Antibody Provides Resistance to Listeria Infection ¹

Brian T. Edelson; Pascale Cossart; Emil R. Unanue

J Immunol (1999) 163 (8): 4087–4090.

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Cutting Edge: NKT Cell Development Is Selectively Impaired in Fyn- Deficient Mice

Gérard Eberl; Bente Lowin-Kropf; H. Robson MacDonald

J Immunol (1999) 163 (8): 4091–4094.

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Cutting Edge: Bacterial DNA and LPS Act in Synergy in Inducing Nitric Oxide Production in RAW 264.7 Macrophages ¹

Jian Jun Gao; Eleanor G. Zuvanich; Qiao Xue; David L. Horn; Richard Silverstein; David C. Morrison

J Immunol (1999) 163 (8): 4095–4099.

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Cutting Edge: TCRαβ⁺ CD8αα⁺ T Cells Are Found in Intestinal Intraepithelial Lymphocytes of Mice That Lack Classical MHC Class I Molecules ¹

Laurent Gapin; Hilde Cheroutre; Mitchell Kronenberg

J Immunol (1999) 163 (8): 4100–4104.

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Cutting Edge: A Dominant Negative Form of TNF-α Converting Enzyme Inhibits ProTNF and TNFRII Secretion

Kimberly A. Solomon; Nancy Pesti; Guoxin Wu; Robert C. Newton

J Immunol (1999) 163 (8): 4105–4108.

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Cutting Edge: Differentiation of Antitumor CTL In Vivo Requires Host Expression of Stat1 ¹

Francesca Fallarino; Thomas F. Gajewski

J Immunol (1999) 163 (8): 4109–4113.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

A Caspase-Independent Pathway of MHC Class II Antigen-Mediated Apoptosis of Human B Lymphocytes ¹

Bernard Drénou; Vincent Blancheteau; David H. Burgess; Renée Fauchet; Dominique J. Charron; Nuala A. Mooney

J Immunol (1999) 163 (8): 4115–4124.

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Induction and Visualization of Mucosal Memory CD8 T Cells Following Systemic Virus Infection ¹

Sung-Kwon Kim; Kimberly S. Schluns; Leo Lefrançois

J Immunol (1999) 163 (8): 4125–4132.

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Cell Surface Expression of the Endoplasmic Reticular Heat Shock Protein gp96 Is Phylogenetically Conserved ¹

Jacques Robert; Antoine Ménoret; Nicholas Cohen

J Immunol (1999) 163 (8): 4133–4139.

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Adenosine Inhibits Macrophage Colony-Stimulating Factor-Dependent Proliferation of Macrophages Through the Induction of p27^kip-1 Expression ¹

Jordi Xaus; Annabel F. Valledor; Marina Cardó; Laura Marquès; Jorge Beleta; José M. Palacios; Antonio Celada

J Immunol (1999) 163 (8): 4140–4149.

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Expression, Regulation, and Function of B Cell-Expressed CD154 in Germinal Centers ¹

Amrie C. Grammer; Richard D. McFarland; Jonathan Heaney; Bonnie F. Darnell; Peter E. Lipsky

J Immunol (1999) 163 (8): 4150–4159.

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Cytokine Requirements for Production of a Novel Anti-CD8-Resistant CTL Population ¹

Esi S. N. Lamousé-Smith; David S. Dougall; Susan A. McCarthy

J Immunol (1999) 163 (8): 4160–4167.

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Estrogen Receptor α Is Necessary in Thymic Development and Estradiol-Induced Thymic Alterations ¹

J. Erin Staples; Thomas A. Gasiewicz; Nancy C. Fiore; Dennis B. Lubahn; Kenneth S. Korach; Allen E. Silverstone

J Immunol (1999) 163 (8): 4168–4174.

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Integrating Signals from IFN-γ and IL-4 by B Cells: Positive and Negative Effects on CD40 Ligand-Induced Proliferation, Survival, and Division-Linked Isotype Switching to IgG1, IgE, and IgG2a ¹

Jhagvaral Hasbold; Jonathan Sui-Yin Hong; Marilyn R. Kehry; Philip D. Hodgkin

J Immunol (1999) 163 (8): 4175–4181.

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Nitric Oxide Suppresses Human T Lymphocyte Proliferation Through IFN-γ-Dependent and IFN-γ-Independent Induction of Apoptosis ¹

Alessandra Allione; Paola Bernabei; Marita Bosticardo; Silvia Ariotti; Guido Forni; Francesco Novelli

J Immunol (1999) 163 (8): 4182–4191.

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Genetic Evidence for Lyn as a Negative Regulator of IL-4 Signaling ¹

Michelle L. Janas; Philip Hodgkin; Margaret Hibbs; David Tarlinton

J Immunol (1999) 163 (8): 4192–4198.

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Characterization of RNA Binding Proteins Associated with CD40 Ligand (CD154) mRNA Turnover in Human T Lymphocytes ¹

W. F. C. Rigby; M. G. Waugh; B. J. Hamilton

J Immunol (1999) 163 (8): 4199–4206.

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NK Cell Triggering by the Human Costimulatory Molecules CD80 and CD86 ¹

Julia L. Wilson; Jehad Charo; Alfonso Martín-Fontecha; Paolo Dellabona; Giulia Casorati; Benedict J. Chambers; Rolf Kiessling; Maria-Teresa Bejarano; Hans-Gustaf Ljunggren

J Immunol (1999) 163 (8): 4207–4212.

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VIP and PACAP Differentially Regulate the Costimulatory Activity of Resting and Activated Macrophages Through the Modulation of B7.1 and B7.2 Expression ¹

Mario Delgado; Wei Sun; Javier Leceta; Doina Ganea

J Immunol (1999) 163 (8): 4213–4223.

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Deficiency of Transporter for Antigen Presentation (TAP) in Tumor Cells Allows Evasion of Immune Surveillance and Increases Tumorigenesis ¹

A. K. Johnsen; D. J. Templeton; M.-S. Sy; C. V. Harding

J Immunol (1999) 163 (8): 4224–4231.

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The Self-Directed T Cell Repertoire Against Mouse Lysozyme Reflects the Influence of the Hierarchy of Its Own Determinants and Can Be Engaged by a Foreign Lysozyme ¹

Kamal D. Moudgil; Scott Southwood; Akio Ametani; Kasey Kim; Alessandro Sette; Eli E. Sercarz

J Immunol (1999) 163 (8): 4232–4237.

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CD2 and CD3 Associate Independently with CD5 and Differentially Regulate Signaling Through CD5 in Jurkat T Cells ¹

Alexandre M. Carmo; Mónica A. A. Castro; Fernando A. Arosa

J Immunol (1999) 163 (8): 4238–4245.

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Role of IL-12 in the Induction and Potentiation of IFN-γ in Response to Bacillus Calmette-Guérin ¹

Michael A. O’Donnell; Yi Luo; Xiaohong Chen; Akos Szilvasi; Sharon E. Hunter; Steven K. Clinton

J Immunol (1999) 163 (8): 4246–4252.

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LFA-1 to LFA-1 Signals Involve ζ-Associated Protein-70 (ZAP-70) Tyrosine Kinase: Relevance for Invasion and Migration of a T Cell Hybridoma ¹

Ron D. M. Soede; Mariëtte H. E. Driessens; Lisette Ruuls-Van Stalle; Paula E. M. Van Hulten; Arjen Brink; Ed Roos

J Immunol (1999) 163 (8): 4253–4261.

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Failure of Rearranged TCR Transgenes to Prevent Age-Associated Thymic Involution ¹

H. Daniel Lacorazza; Jose A. Guevara Patiño; Marc E. Weksler; Dorel Radu; Janko Nikolić-Z̆ugić

J Immunol (1999) 163 (8): 4262–4268.

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Systemic Expression of Rat Soluble Retinal Antigen Induces Resistance to Experimental Autoimmune Uveoretinitis ¹

Scott W. McPherson; Josh P. Roberts; Dale S. Gregerson

J Immunol (1999) 163 (8): 4269–4276.

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A Soluble Factor Produced by Lamina Propria Mononuclear Cells Is Required for TNF-α Enhancement of IFN-γ Production by T Cells ¹

John L. Prehn; Carol J. Landers; Stephan R. Targan

J Immunol (1999) 163 (8): 4277–4283.

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Dendritic Cell-Derived IL-12 Promotes B Cell Induction of Th2 Differentiation: A Feedback Regulation of Th1 Development ¹

Jane Skok; Johanne Poudrier; David Gray

J Immunol (1999) 163 (8): 4284–4291.

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Inhibition of CD28 Expression by Oligonucleotide Decoys to the Regulatory Element in Exon 1 of the CD28 Gene

Robert C. Tam; Catherine J. Lin; Charmaine Lim; Bharati Pai; Vesna Stoisavljevic

J Immunol (1999) 163 (8): 4292–4299.

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Naive and Memory T Lymphocytes Migrate in Comparable Numbers Through Normal Rat Liver: Activated T Cells Accumulate in the Periportal Field ¹

Birgit Luettig; Lars Pape; Ulrike Bode; Eric B. Bell; Sheila M. Sparshott; Siegfried Wagner; Jürgen Westermann

J Immunol (1999) 163 (8): 4300–4307.

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Cerebral Endothelial Cells Release TNF-α After Stimulation with Cell Walls of Streptococcus pneumoniae and Regulate Inducible Nitric Oxide Synthase and ICAM-1 Expression Via Autocrine Loops ¹

Dorette Freyer; Rahel Manz; Andreas Ziegenhorn; Markus Weih; Klemens Angstwurm; Wolf-Dietrich Döcke; Andreas Meisel; Ralf R. Schumann; Gilbert Schönfelder; Ulrich Dirnagl; Joerg R. Weber

J Immunol (1999) 163 (8): 4308–4314.

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Contrasting the In Situ Behavior of a Memory B Cell Clone During Primary and Secondary Immune Responses ¹

Kalpit A. Vora; Kathleen Tumas-Brundage; Tim Manser

J Immunol (1999) 163 (8): 4315–4327.

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Ligation of CD28 In Vivo Induces CD40 Ligand Expression and Promotes B Cell Survival ¹

Deling Yin; Liying Zhang; Ruoxiang Wang; Laszlo Radvanyi; Christian Haudenschild; Qiding Fang; Marilyn R. Kehry; Yufang Shi

J Immunol (1999) 163 (8): 4328–4334.

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Comparing the Relative Role of Perforin/Granzyme Versus Fas/Fas Ligand Cytotoxic Pathways in CD8⁺ T Cell-Mediated Insulin-Dependent Diabetes Mellitus ¹

Huub T. C. Kreuwel; David J. Morgan; Troy Krahl; Alice Ko; Nora Sarvetnick; Linda A. Sherman

J Immunol (1999) 163 (8): 4335–4341.

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Specificity of CTL Interactions with Peptide-MHC Class I Tetrameric Complexes Is Temperature Dependent ¹

Joseph A. Whelan; P. Rod Dunbar; David A. Price; Marco A. Purbhoo; Franziska Lechner; Graham S. Ogg; Gillian Griffiths; Rodney E. Phillips; Vincenzo Cerundolo; Andrew K. Sewell

J Immunol (1999) 163 (8): 4342–4348.

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Role of IL-12 in Intrathymic Negative Selection

Björn R. Lúdvíksson; Rolf O. Ehrhardt; Warren Strober

J Immunol (1999) 163 (8): 4349–4359.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Monoclonal Antibodies That Distinguish Between Two Related Digitalis Glycosides, Ouabain and Digoxin ¹

Behnaz Parhami-Seren; Charles Bell; Michael N. Margolies; Garner T. Haupert, Jr.

J Immunol (1999) 163 (8): 4360–4366.

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Amplitude and Frequency Modulation of Metabolic Signals in Leukocytes: Synergistic Role of IFN-γ in IL-6- and IL-2-Mediated Cell Activation ¹

Yoshiyuki Adachi; Andrei L. Kindzelskii; Naohito Ohno; Toshiro Yadomae; Howard R. Petty

J Immunol (1999) 163 (8): 4367–4374.

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Transcriptional Regulation of the Igκ Gene by Promoter-Proximal Pausing of RNA Polymerase II ¹

Eva E. Raschke; Thomas Albert; Dirk Eick

J Immunol (1999) 163 (8): 4375–4382.

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Functional Synergism of STAT6 with Either NF-κB or PU.1 to Mediate IL-4-Induced Activation of IgE Germline Gene Transcription

Adrian M. Stütz; Maximilian Woisetschläger

J Immunol (1999) 163 (8): 4383–4391.

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A Recurrent Breakpoint in the Most Common Deletion of the Ig Heavy Chain Locus (del A1-GP-G2-G4-E )¹ ^²

Alfredo Brusco; Silvia Saviozzi; Fernanda Cinque; Andrea Bottaro; Mario DeMarchi

J Immunol (1999) 163 (8): 4392–4398.

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The Human Antibody Response to Porcine Xenoantigens Is Encoded by IGHV3-11 and IGHV3-74 IgV_H Germline Progenitors ¹

Mary Kearns-Jonker; Joyce Swensson; Cristina Ghiuzeli; Wilson Chu; Yuka Osame; Vaughn Starnes; Donald V. Cramer

J Immunol (1999) 163 (8): 4399–4412.

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Thermolabile H-2K^b Molecules Expressed by Transporter Associated with Antigen Processing-Deficient RMA-S Cells Are Occupied by Low-Affinity Peptides ¹

A. Dharshan De Silva; Alina Boesteanu; Rui Song; Nancy Nagy; Edward Harhaj; Clifford V. Harding; Sebastian Joyce

J Immunol (1999) 163 (8): 4413–4420.

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An Antibody-Avidin Fusion Protein Specific for the Transferrin Receptor Serves as a Delivery Vehicle for Effective Brain Targeting: Initial Applications in Anti-HIV Antisense Drug Delivery to the Brain ¹

Manuel L. Penichet; Young-Sook Kang; William M. Pardridge; Sherie L. Morrison; Seung-Uon Shin

J Immunol (1999) 163 (8): 4421–4426.

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An Extensive Region of an MHC Class I α2 Domain Loop Influences Interaction with the Assembly Complex ¹

Yik Y. L. Yu; H¯eth R. Turnquist; Nancy B. Myers; Ganesaratnam K. Balendiran; Ted H. Hansen; Joyce C. Solheim

J Immunol (1999) 163 (8): 4427–4433.

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Binding of Longer Peptides to the H-2K^b Heterodimer Is Restricted to Peptides Extended at Their C Terminus: Refinement of the Inherent MHC Class I Peptide Binding Criteria ¹

Heidi Hörig; Aideen C. M. Young; Nicholas J. Papadopoulos; Teresa P. DiLorenzo; Stanley G. Nathenson

J Immunol (1999) 163 (8): 4434–4441.

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HOST DEFENSE

The Epithelial Cell Response to Rotavirus Infection ¹

Ellen E. Rollo; K. Prasanna Kumar; Nancy C. Reich; Jean Cohen; Juana Angel; Harry B. Greenberg; Riten Sheth; Joseph Anderson; Brian Oh; Scott J. Hempson; Erich R. Mackow; Robert D. Shaw

J Immunol (1999) 163 (8): 4442–4452.

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The NF-κB Family Member RelB Is Required for Innate and Adaptive Immunity to Toxoplasma gondii¹

Jorge Caamaño; James Alexander; Linden Craig; Rodrigo Bravo; Christopher A. Hunter

J Immunol (1999) 163 (8): 4453–4461.

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Tumor Regression After Adoptive Transfer of Effector T Cells Is Independent of Perforin or Fas Ligand (APO-1L/CD95L)¹

Hauke Winter; Hong-Ming Hu; Walter J. Urba; Bernard A. Fox

J Immunol (1999) 163 (8): 4462–4472.

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Up-Regulation of NK Cytotoxic Activity Via IL-15 Induction by Different Viruses: A Comparative Study ¹

Lama M. Fawaz; Ehsan Sharif-Askari; José Menezes

J Immunol (1999) 163 (8): 4473–4480.

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Protective Immunity Using Recombinant Human IL-12 and Alum as Adjuvants in a Primate Model of Cutaneous Leishmaniasis ¹

Richard T. Kenney; David L. Sacks; Joseph P. Sypek; Luciano Vilela; Albert A. Gam; Kamela Evans-Davis

J Immunol (1999) 163 (8): 4481–4488.

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TNF Is Essential for the Cell-Mediated Protective Immunity Induced by the Radiation-Attenuated Schistosome Vaccine ¹

Miyoko Street; Patricia S. Coulson; Clare Sadler; Lorna J. Warnock; Deborah McLaughlin; Horst Bluethmann; R. Alan Wilson

J Immunol (1999) 163 (8): 4489–4494.

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Surfactant Protein A Down-Regulates Proinflammatory Cytokine Production Evoked by Candida albicans in Human Alveolar Macrophages and Monocytes ¹

Simone Rosseau; Peter Hammerl; Ulrich Maus; Andreas Günther; Werner Seeger; Friedrich Grimminger; Jürgen Lohmeyer

J Immunol (1999) 163 (8): 4495–4502.

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IL-15 Prolongs the Duration of CD8⁺ T Cell-Mediated Immunity in Mice Infected with a Vaccine Strain of Toxoplasma gondii¹

Imtiaz A. Khan; Lori Casciotti

J Immunol (1999) 163 (8): 4503–4509.

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Effective DNA Vaccination Against Listeriosis by Prime/Boost Inoculation with the Gene Gun ¹

Joachim Fensterle; Leander Grode; Jürgen Hess; Stefan H. E. Kaufmann

J Immunol (1999) 163 (8): 4510–4518.

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INFLAMMATION

Nitric Oxide Participates in the Recovery of Normal Jejunal Epithelial Ion Transport Following Exposure to the Superantigen, Staphylococcus aureus Enterotoxin B ¹

Derek M. McKay; Jun Lu; Sean Jedrzkiewicz; Winnie Ho; Keith A. Sharkey

J Immunol (1999) 163 (8): 4519–4526.

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Activation of p90^RSK and cAMP Response Element Binding Protein in Stimulated Neutrophils: Novel Effects of the Pyridinyl Imidazole SB 203580 on Activation of the Extracellular Signal-Regulated Kinase Cascade ¹

Jian P. Lian; RiYun Huang; Dwight Robinson; John A. Badwey

J Immunol (1999) 163 (8): 4527–4536.

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Posttranscriptional Regulation of Acute Phase Serum Amyloid A2 Expression by the 5′- and 3′-Untranslated Regions of Its mRNA ¹

Daniel B. Longley; Diana M. Steel; Alexander S. Whitehead

J Immunol (1999) 163 (8): 4537–4545.

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Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction ¹

Erik Lubberts; Leo A. B. Joosten; Liduine van den Bersselaar; Monique M. A. Helsen; Andrew C. Bakker; Joyce B. J. van Meurs; Frank L. Graham; Carl D. Richards; Wim B. van den Berg

J Immunol (1999) 163 (8): 4546–4556.

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Activated Lymphocytes Promote Endothelial Cell Detachment from Matrix: A Role for Modulation of Endothelial Cell β₁ Integrin Affinity ¹

Cecile Phan; Alan W. McMahon; Randall C. Nelson; John F. Elliott; Allan G. Murray

J Immunol (1999) 163 (8): 4557–4563.

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Ectosomes Released by Human Neutrophils Are Specialized Functional Units ¹

Christoph Hess; Salima Sadallah; Andreas Hefti; Regine Landmann; Jürg-Alfred Schifferli

J Immunol (1999) 163 (8): 4564–4573.

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Protein Kinase C (PKC) Isoforms Translocate to Triton-Insoluble Fractions in Stimulated Human Neutrophils: Correlation of Conventional PKC with Activation of NADPH Oxidase ¹

Jennifer B. Nixon; Linda C. McPhail

J Immunol (1999) 163 (8): 4574–4582.

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Novel Path to Activation of Vascular Smooth Muscle Cells: Up-Regulation of gp130 Creates an Autocrine Activation Loop by IL-6 and Its Soluble Receptor ¹

Mariam Klouche; Sucharit Bhakdi; Monika Hemmes; Stefan Rose-John

J Immunol (1999) 163 (8): 4583–4589.

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CLINICAL IMMUNOLOGY

Nephritogenic λ Light Chain Dimer: A Unique Human Miniautoantibody Against Complement Factor H ¹

T. Sakari Jokiranta; Alan Solomon; Michael K. Pangburn; Peter F. Zipfel; Seppo Meri

J Immunol (1999) 163 (8): 4590–4596.

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CC Chemokine Receptor 5 Cell-Surface Expression in Relation to CC Chemokine Receptor 5 Genotype and the Clinical Course of HIV-1 Infection ¹

Ana-Maria de Roda Husman; Hetty Blaak; Margreet Brouwer; Hanneke Schuitemaker

J Immunol (1999) 163 (8): 4597–4603.

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Isolation, Characterization and Sequence Analysis of Five IgG Monoclonal Anti-β₂-Glycoprotein-1 and Anti-Prothrombin Antigen-Binding Fragments Generated by Phage Display ¹

Reginald U. Chukwuocha; Elie T. Hsiao; Peter Shaw; Joseph L. Witztum; Pojen P. Chen

J Immunol (1999) 163 (8): 4604–4611.

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C1q-Containing Immune Complexes Purified from Sera of Juvenile Rheumatoid Arthritis Patients Mediate IL-8 Production by Human Synoviocytes: Role of C1q Receptors ¹

Zhila Khalkhali-Ellis; Gary A. Bulla; Larry S. Schlesinger; Dawn A. Kirschmann; Terry L. Moore; Mary J. C. Hendrix

J Immunol (1999) 163 (8): 4612–4620.

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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