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CUTTING EDGE

Cutting Edge: Polycomb Gene Expression Patterns Reflect Distinct B Cell Differentiation Stages in Human Germinal Centers

Frank M. Raaphorst; Folkert J. van Kemenade; Elly Fieret; Karien M. Hamer; David P. E. Satijn; Arie P. Otte; Chris J. L. M. Meijer

J Immunol (2000) 164 (1): 1–4.

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Cutting Edge: Tyrosine-Independent Transmission of Inhibitory Signals by CTLA-4 ¹

Tomas Cinek; Ali Sadra; John B. Imboden

J Immunol (2000) 164 (1): 5–8.

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Cutting Edge: Signal-Regulatory Protein β1 Is a DAP12-Associated Activating Receptor Expressed in Myeloid Cells ¹

Jes Dietrich; Marina Cella; Martina Seiffert; Hans-Jörg Bühring; Marco Colonna

J Immunol (2000) 164 (1): 9–12.

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Cutting Edge: Heat Shock Protein (HSP) 60 Activates the Innate Immune Response: CD14 Is an Essential Receptor for HSP60 Activation of Mononuclear Cells ¹

Amir Kol; Andrew H. Lichtman; Robert W. Finberg; Peter Libby; Evelyn A. Kurt-Jones

J Immunol (2000) 164 (1): 13–17.

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Cutting Edge: Lack of Peripheral B Cells and Severe Agammaglobulinemia in Mice Simultaneously Lacking Bruton’s Tyrosine Kinase and the B Cell-Specific Transcriptional Coactivator OBF-1

Daniel B. Schubart; Antonius Rolink; Karin Schubart; Patrick Matthias

J Immunol (2000) 164 (1): 18–22.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

IFN-β Differentially Regulates CD40-Induced Cytokine Secretion by Human Dendritic Cells ¹

Bradford L. McRae; Beth A. Beilfuss; Gijs A. van Seventer

J Immunol (2000) 164 (1): 23–28.

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Protein Kinase Cε Is Required for the Induction of Mitogen-Activated Protein Kinase Phosphatase-1 in Lipopolysaccharide-Stimulated Macrophages ¹

Annabel F. Valledor; Jordi Xaus; Mònica Comalada; Concepció Soler; Antonio Celada

J Immunol (2000) 164 (1): 29–37.

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Development of Lupus in BXSB Mice Is Independent of IL-4 ¹

Dwight H. Kono; Dimitrios Balomenos; Miyo S. Park; Argyrios N. Theofilopoulos

J Immunol (2000) 164 (1): 38–42.

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Human Intestinal Mast Cells Are Capable of Producing Different Cytokine Profiles: Role of IgE Receptor Cross-Linking and IL-4 ¹

Axel Lorentz; Silke Schwengberg; Gernot Sellge; Michael P. Manns; Stephan C. Bischoff

J Immunol (2000) 164 (1): 43–48.

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The Inhibitory Function of CTLA-4 Does Not Require Its Tyrosine Phosphorylation ¹

Miren L. Baroja; Deborah Luxenberg; Thu Chau; Vincent Ling; Craig A. Strathdee; Beatriz M. Carreno; Joaquín Madrenas

J Immunol (2000) 164 (1): 49–55.

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Distinct Role of Follicular Dendritic Cells and T Cells in the Proliferation, Differentiation, and Apoptosis of a Centroblast Cell Line, L3055 ¹

Jongseon Choe; Li Li; Xin Zhang; Christopher D. Gregory; Yong Sung Choi

J Immunol (2000) 164 (1): 56–63.

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Synergistic Effects of IL-4 and IL-18 on IL-12-Dependent IFN-γ Production by Dendritic Cells ¹

Taro Fukao; Satoshi Matsuda; Shigeo Koyasu

J Immunol (2000) 164 (1): 64–71.

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Inhibition of IL-4 Responses After T Cell Priming in the Context of LFA-1 Costimulation Is Not Reversed by Restimulation in the Presence of CD28 Costimulation ¹

Scott A. Jenks; Jim Miller

J Immunol (2000) 164 (1): 72–78.

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Differential Requirement for CD80 and CD80/CD86-Dependent Costimulation in the Lung Immune Response to an Influenza Virus Infection ¹

Joanne M. Lumsden; Joanna M. Roberts; Nicola L. Harris; Robert J. Peach; Franca Ronchese

J Immunol (2000) 164 (1): 79–85.

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Bovine and Human Insulin Activate CD8⁺-Autoreactive CTL Expressing Both Type 1 and Type 2 Cytokines in C57BL/6 Mice ¹

Hakling Ma; Yong Ke; Qingqin Li; Judith A. Kapp

J Immunol (2000) 164 (1): 86–92.

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An Early Pseudorabies Virus Protein Down-Regulates Porcine MHC Class I Expression by Inhibition of Transporter Associated with Antigen Processing (TAP)

Aruna P. N. Ambagala; Susanne Hinkley; Subramaniam Srikumaran

J Immunol (2000) 164 (1): 93–99.

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Role of Costimulation in the Induction of the IL-12/IL-12 Receptor Pathway and the Development of Autoimmunity

John T. Chang; Benjamin M. Segal; Ethan M. Shevach

J Immunol (2000) 164 (1): 100–106.

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Danger and OX40 Receptor Signaling Synergize to Enhance Memory T Cell Survival by Inhibiting Peripheral Deletion ¹

Joseph R. Maxwell; Andrew Weinberg; Rodney A. Prell; Anthony T. Vella

J Immunol (2000) 164 (1): 107–112.

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Developmental Expression of Insulin Receptor Substrate-2 During Dimethylsulfoxide-Induced Differentiation of Human HL-60 Cells ¹

Daniel H. Schacher; Roger W. VanHoy; Qiang Liu; Sean Arkins; Robert Dantzer; Gregory G. Freund; Keith W. Kelley

J Immunol (2000) 164 (1): 113–120.

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Deriving Quantitative Constraints on T Cell Selection from Data on the Mature T Cell Repertoire ¹

Vincent Detours; Ramit Mehr; Alan S. Perelson

J Immunol (2000) 164 (1): 121–128.

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Modification of the Amino Terminus of a Class II Epitope Confers Resistance to Degradation by CD13 on Dendritic Cells and Enhances Presentation to T Cells ¹

Xin Dong; Bing An; Lisa Salvucci Kierstead; Walter J. Storkus; Andrew A. Amoscato; Russell D. Salter

J Immunol (2000) 164 (1): 129–135.

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A Critical Role for B7/CD28 Costimulation in Experimental Autoimmune Encephalomyelitis: A Comparative Study Using Costimulatory Molecule-Deficient Mice and Monoclonal Antibody Blockade ¹

Ann M. Girvin; Mauro C. Dal Canto; Lesley Rhee; Benoît Salomon; Arlene Sharpe; Jeffrey A. Bluestone; Stephen D. Miller

J Immunol (2000) 164 (1): 136–143.

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CD28 Costimulation Mediates T Cell Expansion Via IL-2-Independent and IL-2-Dependent Regulation of Cell Cycle Progression ¹

Leonard J. Appleman; Alla Berezovskaya; Isabelle Grass; Vassiliki A. Boussiotis

J Immunol (2000) 164 (1): 144–151.

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Effects of T3Rα1 and T3Rα2 Gene Deletion on T and B Lymphocyte Development ¹

Christophe Arpin; Maria Pihlgren; Alexandre Fraichard; Denise Aubert; Jacques Samarut; Olivier Chassande; Jacqueline Marvel

J Immunol (2000) 164 (1): 152–160.

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Dendritic Cells Genetically Engineered to Express Fas Ligand Induce Donor-Specific Hyporesponsiveness and Prolong Allograft Survival ¹

Wei-Ping Min; Reginald Gorczynski; Xu-Yan Huang; Michelle Kushida; Peter Kim; Masayuki Obataki; Ji Lei; Rakesh M. Suri; Mark S. Cattral

J Immunol (2000) 164 (1): 161–167.

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Bacterial Proteins Can Be Processed by Macrophages in a Transporter Associated with Antigen Processing-Independent, Cysteine Protease-Dependent Manner for Presentation by MHC Class I Molecules ¹

Daniel J. Campbell; Thomas Serwold; Nilabh Shastri

J Immunol (2000) 164 (1): 168–175.

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Glycine Inhibits Growth of T Lymphocytes by an IL-2-Independent Mechanism ¹

Robert F. Stachlewitz; Xiangli Li; Scott Smith; Hartwig Bunzendahl; Lee M. Graves; Ronald G. Thurman

J Immunol (2000) 164 (1): 176–182.

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Suppressor Effector Function of CD4⁺CD25⁺ Immunoregulatory T Cells Is Antigen Nonspecific

Angela M. Thornton; Ethan M. Shevach

J Immunol (2000) 164 (1): 183–190.

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Characterization of CD8⁺ T Lymphocytes That Persist After Peripheral Tolerance to a Self Antigen Expressed in the Pancreas ¹

C. Thomas Nugent; David J. Morgan; Judith A. Biggs; Alice Ko; Ingrid M. Pilip; Eric G. Pamer; Linda A. Sherman

J Immunol (2000) 164 (1): 191–200.

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Surface Expression of the IFN-γR2 Chain Is Regulated by Intracellular Trafficking in Human T Lymphocytes ¹

Laura Rigamonti; Silvia Ariotti; Giuliana Losana; Roberto Gradini; Matteo A. Russo; Emmanuelle Jouanguy; Jean-Laurent Casanova; Guido Forni; Francesco Novelli

J Immunol (2000) 164 (1): 201–207.

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Activated and Memory CD8⁺ T Cells Can Be Distinguished by Their Cytokine Profiles and Phenotypic Markers ¹

Mark K. Slifka; J. Lindsay Whitton

J Immunol (2000) 164 (1): 208–216.

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Gene Transfer of IFN-γ into Established Brain Tumors Represses Growth by Antiangiogenesis

Hassan M. Fathallah-Shaykh; Li-Juan Zhao; Abdallah I. Kafrouni; George M. Smith; James Forman

J Immunol (2000) 164 (1): 217–222.

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Vaccination with Heat-Killed Listeria as Adjuvant Reverses Established Allergen-Induced Airway Hyperreactivity and Inflammation: Role of CD8⁺ T Cells and IL-18 ¹

Gesine Hansen; V. Peter Yeung; Gerald Berry; Dale T. Umetsu; Rosemarie H. DeKruyff

J Immunol (2000) 164 (1): 223–230.

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IFN-γ-Dependent Delay of In Vivo Tumor Progression by Fas Overexpression on Murine Renal Cancer Cells ¹ ^²

Jong-Keuk Lee; Thomas J. Sayers; Alan D. Brooks; Timothy C. Back; Howard A. Young; Kristin L. Komschlies; Jon M. Wigginton; Robert H. Wiltrout

J Immunol (2000) 164 (1): 231–239.

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Characterization of Peripheral Regulatory CD4⁺ T Cells That Prevent Diabetes Onset in Nonobese Diabetic Mice ¹

Françoise Lepault; Marie Claude Gagnerault

J Immunol (2000) 164 (1): 240–247.

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Th2-Dependent B Cell Responses in the Absence of CD40-CD40 Ligand Interactions ¹

Narendra Chirmule; John Tazelaar; James M. Wilson

J Immunol (2000) 164 (1): 248–255.

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A Role for Pref-1 and HES-1 in Thymocyte Development

Midori Kaneta; Masatake Osawa; Mitsujiro Osawa; Kazuhiro Sudo; Hiromitsu Nakauchi; Andrew G. Farr; Yousuke Takahama

J Immunol (2000) 164 (1): 256–264.

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Functional Responses and Costimulator Dependence of Memory CD4⁺ T Cells ¹

Cheryl A. London; Michael P. Lodge; Abul K. Abbas

J Immunol (2000) 164 (1): 265–272.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Importance of the Membrane-Proximal Extracellular Domains for Activation of the Signal Transducer Glycoprotein 130 ¹

Ingo Kurth; Ursula Horsten; Stefan Pflanz; Andreas Timmermann; Andrea Küster; Heike Dahmen; Ingrid Tacken; Peter C. Heinrich; Gerhard Müller-Newen

J Immunol (2000) 164 (1): 273–282.

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Conserved MHC Class I Peptide Binding Motif Between Humans and Rhesus Macaques ¹

John L. Dzuris; John Sidney; Ettore Appella; Robert W. Chesnut; David I. Watkins; Alessandro Sette

J Immunol (2000) 164 (1): 283–291.

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Distinct Functions of Tapasin Revealed by Polymorphism in MHC Class I Peptide Loading ¹

Chen Au Peh; Nihay Laham; Scott R. Burrows; Yong Zhu; James McCluskey

J Immunol (2000) 164 (1): 292–299.

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The Role of Sp Family Members, Basic Krupple-Like Factor, and E Box Factors in the Basal and IFN-γ Regulated Expression of the Human Complement C4 Promoter ¹

Daniela Ulgiati; Lily S. Subrata; Lawrence J. Abraham

J Immunol (2000) 164 (1): 300–307.

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Anergic T Lymphocytes Selectively Express an Integrin Regulatory Protein of the Cytohesin Family ¹

Ulf Korthäuer; Wolfgang Nagel; Elizabeth M. Davis; Michelle M. Le Beau; Raman S. Menon; Elizabeth O. Mitchell; Christine A. Kozak; Waldemar Kolanus; Jeffrey A. Bluestone

J Immunol (2000) 164 (1): 308–318.

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HLA-F Is a Predominantly Empty, Intracellular, TAP-Associated MHC Class Ib Protein with a Restricted Expression Pattern ¹

Shane D. Wainwright; P. Andrew Biro; Christopher H. Holmes

J Immunol (2000) 164 (1): 319–328.

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Limited Diversity of Peptides Related to an Alloreactive T Cell Epitope in the HLA-B27-Bound Peptide Repertoire Results from Restrictions at Multiple Steps Along the Processing-Loading Pathway ¹

Alberto Paradela; Iñaki Alvarez; Marina García-Peydró; Laura Sesma; Manuel Ramos; Jesús Vázquez; José A. López de Castro

J Immunol (2000) 164 (1): 329–337.

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Point Mutation of a Tyrosine in the Linker Region of Syk Results in a Gain of Function

Kiyonao Sada; Juan Zhang; Reuben P. Siraganian

J Immunol (2000) 164 (1): 338–344.

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Rescue of Defective T Cell Development and Function in Atm^−/− Mice by a Functional TCRαβ Transgene ¹

Connie Chao; Eva Marie Yang; Yang Xu

J Immunol (2000) 164 (1): 345–349.

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Convergence of Fcγ Receptor IIA and Fcγ Receptor IIIB Signaling Pathways in Human Neutrophils ¹

Frank Y. S. Chuang; Massimo Sassaroli; Jay C. Unkeless

J Immunol (2000) 164 (1): 350–360.

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HOST DEFENSE

Specific Inhibition of Cyclooxygenase 2 Restores Antitumor Reactivity by Altering the Balance of IL-10 and IL-12 Synthesis ¹

Marina Stolina; Sherven Sharma; Ying Lin; Mariam Dohadwala; Brian Gardner; Jie Luo; Li Zhu; Mitchell Kronenberg; Patrice W. Miller; Joseph Portanova; Jason C. Lee; Steven M. Dubinett

J Immunol (2000) 164 (1): 361–370.

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IL-4 and IL-10 Antagonize IL-12-Mediated Protection Against Acute Vaccinia Virus Infection with a Limited Role of IFN-γ and Nitric Oxide Synthetase 2 ¹

Maries van den Broek; Martin F. Bachmann; Gabriele Köhler; Marijke Barner; Rüdiger Escher; Rolf Zinkernagel; Manfred Kopf

J Immunol (2000) 164 (1): 371–378.

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ATP-Induced Killing of Virulent Mycobacterium tuberculosis Within Human Macrophages Requires Phospholipase D ¹

David J. Kusner; Juan Adams

J Immunol (2000) 164 (1): 379–388.

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Macrophage Control of Mycobacterial Growth Induced by Picolinic Acid Is Dependent on Host Cell Apoptosis ¹

Teresa F. Pais; Rui Appelberg

J Immunol (2000) 164 (1): 389–397.

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Differential Contribution of Fas- and Perforin-Mediated Mechanisms to the Cell-Mediated Cytotoxic Activity of Naive and In Vivo-Primed Intestinal Intraepithelial Lymphocytes ¹

Nadia Corazza; Stefan Müller; Thomas Brunner; David Kägi; Christoph Mueller

J Immunol (2000) 164 (1): 398–403.

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fMet-Leu-Phe Stimulates Proinflammatory Cytokine Gene Expression in Human Peripheral Blood Monocytes: The Role of Phosphatidylinositol 3-Kinase ¹

Zhixing K. Pan; Ling-Yu Chen; Charles G. Cochrane; Bruce L. Zuraw

J Immunol (2000) 164 (1): 404–411.

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INFLAMMATION

Role of B7-CD28/CTLA-4 Costimulation and NF-κB in Allergen-Induced T Cell Chemotaxis by IL-16 and RANTES ¹

Rabia Hidi; Vanessa Riches; Musa Al-Ali; William W. Cruikshank; David M. Center; Stephen T. Holgate; Ratko Djukanović

J Immunol (2000) 164 (1): 412–418.

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Kinetics and Cellular Origin of Cytokines in the Central Nervous System: Insight into Mechanisms of Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis ¹

Amy E. Juedes; Peter Hjelmström; Cheryl M. Bergman; Annie L. Neild; Nancy H. Ruddle

J Immunol (2000) 164 (1): 419–426.

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Monocyte Migration Through the Alveolar Epithelial Barrier: Adhesion Molecule Mechanisms and Impact of Chemokines ¹

Simone Rosseau; Jochen Selhorst; Kristina Wiechmann; Katja Leissner; Ulrich Maus; Konstantin Mayer; Friedrich Grimminger; Werner Seeger; Jürgen Lohmeyer

J Immunol (2000) 164 (1): 427–435.

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Ligand-Activation of the Adenosine A2a Receptors Inhibits IL-12 Production by Human Monocytes

Amrey A. Link; Tomoshige Kino; James A. Worth; Jennifer L. McGuire; Marianna L. Crane; George P. Chrousos; Ronald L. Wilder; Ilia J. Elenkov

J Immunol (2000) 164 (1): 436–442.

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TNF-α Receptor Signaling and IL-10 Gene Therapy Regulate the Innate and Humoral Immune Responses to Recombinant Adenovirus in the Lung ¹

Rebecca M. Minter; John E. Rectenwald; Kunitaro Fukuzuka; Cynthia L. Tannahill; Drake La Face; Van Tsai; Iqbal Ahmed; Elizabeth Hutchins; Richard Moyer; Edward M. Copeland, III; Lyle L. Moldawer

J Immunol (2000) 164 (1): 443–451.

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Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutrophil Recruitment ¹

Marian T. Nakada; Kunjlata Amin; Melpo Christofidou-Solomidou; Christopher D. O’Brien; Jing Sun; Indira Gurubhagavatula; George A. Heavner; Alexander H. Taylor; Cathy Paddock; Qi-Hong Sun; James L. Zehnder; Peter J. Newman; Steven M. Albelda; Horace M. DeLisser

J Immunol (2000) 164 (1): 452–462.

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The Arthus Reaction in Rodents: Species-Specific Requirement of Complement ¹

Alexander J. Szalai; Stanley B. Digerness; Alok Agrawal; John F. Kearney; R. Pat Bucy; Shri Niwas; John M. Kilpatrick; Y. Sudhakara Babu; John E. Volanakis

J Immunol (2000) 164 (1): 463–468.

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CLINICAL IMMUNOLOGY

Fas-Deficient lpr Mice Are More Susceptible to Graft-Versus-Host Disease ¹

Marcel R. M. van den Brink; Ellen Moore; Kirsten J. Horndasch; James M. Crawford; Jean Hoffman; George F. Murphy; Steven J. Burakoff

J Immunol (2000) 164 (1): 469–480.

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Immunogenicity and Arthritogenicity of Recombinant CB10 in B10.RIII Mice ¹

Bo Tang; David D. Brand; Tom M. Chiang; John M. Stuart; Andrew H. Kang; Linda K. Myers

J Immunol (2000) 164 (1): 481–487.

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Up-Regulation of IL-12 in Monocytes: A Fundamental Defect in Common Variable Immunodeficiency ¹

Rosario Cambronero; W. A. Carrock Sewell; Margaret E. North; A. David B. Webster; John Farrant

J Immunol (2000) 164 (1): 488–494.

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Expansion of Tumor-T Cell Pairs from Fine Needle Aspirates of Melanoma Metastases

Monica C. Panelli; Adam Riker; Udai Kammula; Ena Wang; Kang-Hun Lee; Steven A. Rosenberg; Francesco M. Marincola

J Immunol (2000) 164 (1): 495–504.

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Protection of Murine Lupus by the Ea^d Transgene Is MHC Haplotype-Dependent ¹

Nabila Ibnou-Zekri; Masahiro Iwamoto; M. Eric Gershwin; Shozo Izui

J Immunol (2000) 164 (1): 505–511.

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Treatment of Allograft Recipients with Donor-Specific Transfusion and Anti-CD154 Antibody Leads to Deletion of Alloreactive CD8⁺ T Cells and Prolonged Graft Survival in a CTLA4-Dependent Manner ¹

Neal N. Iwakoshi; John P. Mordes; Thomas G. Markees; Nancy E. Phillips; Aldo A. Rossini; Dale L. Greiner

J Immunol (2000) 164 (1): 512–521.

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Immune Modulation in Pemphigus Vulgaris: Role of CD28 and IL-10 ¹

Paola Toto; Claudio Feliciani; Paolo Amerio; Hirotake Suzuki; Binghe Wang; Gulnar M. Shivji; David Woodley; Daniel N. Sauder

J Immunol (2000) 164 (1): 522–529.

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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