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CUTTING EDGE

Cutting Edge: Cationic Antimicrobial Peptides Block the Binding of Lipopolysaccharide (LPS) to LPS Binding Protein ¹

Monisha G. Scott; Anita C. E. Vreugdenhil; Wim A. Buurman; Robert E. W. Hancock; Michael R. Gold

J Immunol (2000) 164 (2): 549–553.

Abstract

View articletitled, Cutting Edge: Cationic Antimicrobial Peptides Block the Binding of Lipopolysaccharide (LPS) to LPS Binding Protein<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway ¹

Osamu Takeuchi; Andreas Kaufmann; Karsten Grote; Taro Kawai; Katsuaki Hoshino; Michael Morr; Peter F. Mühlradt; Shizuo Akira

J Immunol (2000) 164 (2): 554–557.

Abstract

View articletitled, Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex ¹

Koji Ohashi; Volker Burkart; Stefanie Flohé; Hubert Kolb

J Immunol (2000) 164 (2): 558–561.

Abstract

View articletitled, Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: CD4⁺ T Cell Control of CD8⁺ T Cell Reactivity to a Model Tumor Antigen

Deborah R. Surman; Mark E. Dudley; Willem W. Overwijk; Nicholas P. Restifo

J Immunol (2000) 164 (2): 562–565.

Abstract

View articletitled, Cutting Edge: CD4+ T Cell Control of CD8+ T Cell Reactivity to a Model Tumor Antigen

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

IFN-α-Expressing Tumor Cells Enhance Generation and Promote Survival of Tumor-Specific CTLs

Kazumasa Hiroishi; Thomas Tüting; Michael T. Lotze

J Immunol (2000) 164 (2): 567–572.

Abstract

View articletitled, IFN-α-Expressing Tumor Cells Enhance Generation and Promote Survival of Tumor-Specific CTLs

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Presentation of IFN-γ to Nitric Oxide-Producing Cells: A Novel Function for Mast Cells ¹

Bernadette Brooks; David M. Briggs; Nigel C. Eastmond; David G. Fernig; John W. Coleman

J Immunol (2000) 164 (2): 573–579.

Abstract

View articletitled, Presentation of IFN-γ to Nitric Oxide-Producing Cells: A Novel Function for Mast Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Th2 Responses by Peptide Analogues in a Murine Model of Allergic Asthma: Amelioration or Deterioration of the Disease Process Depends on the Th1 or Th2 Skewing Characteristics of the Therapeutic Peptide ¹

Edith M. Janssen; Antoon J. M. van Oosterhout; Annemiek J. M. L. van Rensen; Willem van Eden; Frans P. Nijkamp; Marca H. M. Wauben

J Immunol (2000) 164 (2): 580–588.

Abstract

View articletitled, Modulation of Th2 Responses by Peptide Analogues in a Murine Model of Allergic Asthma: Amelioration or Deterioration of the Disease Process Depends on the Th1 or Th2 Skewing Characteristics of the Therapeutic Peptide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HIV-1 gp120 Induces IL-4 and IL-13 Release from Human FcεRI⁺ Cells Through Interaction with the V_H3 Region of IgE ¹

Vincenzo Patella; Giovanni Florio; Angelica Petraroli; Gianni Marone

J Immunol (2000) 164 (2): 589–595.

Abstract

View articletitled, HIV-1 gp120 Induces IL-4 and IL-13 Release from Human FcεRI+ Cells Through Interaction with the VH3 Region of IgE<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Use of HLA A2.1/p53 Peptide Tetramers to Visualize the Impact of Self Tolerance on the TCR Repertoire ¹

Javier Hernández; Peter P. Lee; Mark M. Davis; Linda A. Sherman

J Immunol (2000) 164 (2): 596–602.

Abstract

View articletitled, The Use of HLA A2.1/p53 Peptide Tetramers to Visualize the Impact of Self Tolerance on the TCR Repertoire<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Interaction of Ly-49D⁺ NK Cells with H-2D^d Target Cells Leads to Dap-12 Phosphorylation and IFN-γ Secretion ¹

Llewellyn H. Mason; Jamie Willette-Brown; Anna T. Mason; Daniel McVicar; John R. Ortaldo

J Immunol (2000) 164 (2): 603–611.

Abstract

View articletitled, Interaction of Ly-49D+ NK Cells with H-2Dd Target Cells Leads to Dap-12 Phosphorylation and IFN-γ Secretion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Analysis of the Requirements for the Induction of CD4⁺ T Cell Alloantigen Hyporesponsiveness by Ex Vivo Anti-CD40 Ligand Antibody ¹

Patricia A. Taylor; Angela Panoskaltsis-Mortari; Randolph J. Noelle; Bruce R. Blazar

J Immunol (2000) 164 (2): 612–622.

Abstract

View articletitled, Analysis of the Requirements for the Induction of CD4+ T Cell Alloantigen Hyporesponsiveness by Ex Vivo Anti-CD40 Ligand Antibody<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of the Roles of TNF Receptor-Associated Factor 6 in CD40-Mediated B Lymphocyte Effector Functions ¹

Sangita V. Jalukar; Bruce S. Hostager; Gail A. Bishop

J Immunol (2000) 164 (2): 623–630.

Abstract

View articletitled, Characterization of the Roles of TNF Receptor-Associated Factor 6 in CD40-Mediated B Lymphocyte Effector Functions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Effects of Src Homology Domain 2 (SH2)-Containing Inositol Phosphatase (SHIP), SH2-Containing Phosphotyrosine Phosphatase (SHP)-1, and SHP-2 SH2 Decoy Proteins on FcγRIIB1-Effector Interactions and Inhibitory Functions ¹

Kazuhiro Nakamura; Anne Brauweiler; John C. Cambier

J Immunol (2000) 164 (2): 631–638.

Abstract

View articletitled, Effects of Src Homology Domain 2 (SH2)-Containing Inositol Phosphatase (SHIP), SH2-Containing Phosphotyrosine Phosphatase (SHP)-1, and SHP-2 SH2 Decoy Proteins on FcγRIIB1-Effector Interactions and Inhibitory Functions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Murine CCR9, a Chemokine Receptor for Thymus-Expressed Chemokine That Is Up-Regulated Following Pre-TCR Signaling ¹

Anne M. Norment; Lisa Y. Bogatzki; Ben N. Gantner; Michael J. Bevan

J Immunol (2000) 164 (2): 639–648.

Abstract

View articletitled, Murine CCR9, a Chemokine Receptor for Thymus-Expressed Chemokine That Is Up-Regulated Following Pre-TCR Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vivo CD4⁺ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions ¹

Adam J. Adler; Ching-Tai Huang; Gregory S. Yochum; David W. Marsh; Drew M. Pardoll

J Immunol (2000) 164 (2): 649–655.

Abstract

View articletitled, In Vivo CD4+ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The p55 TNF-α Receptor Plays a Critical Role in T Cell Alloreactivity ¹

Geoffrey R. Hill; Takanori Teshima; Vivienne I. Rebel; Oleg I. Krijanovski; Kenneth R. Cooke; Yani S. Brinson; James L. M. Ferrara

J Immunol (2000) 164 (2): 656–663.

Abstract

View articletitled, The p55 TNF-α Receptor Plays a Critical Role in T Cell Alloreactivity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Blockade of CTLA-4 Signals Inhibits Th2-Mediated Murine Chronic Graft-Versus-Host Disease by an Enhanced Expansion of Regulatory CD8⁺ T Cells ¹

Jinkyo Sakurai; Junko Ohata; Kiyoshi Saito; Hiroaki Miyajima; Takao Hirano; Takao Kohsaka; Shoji Enomoto; Ko Okumura; Miyuki Azuma

J Immunol (2000) 164 (2): 664–669.

Abstract

View articletitled, Blockade of CTLA-4 Signals Inhibits Th2-Mediated Murine Chronic Graft-Versus-Host Disease by an Enhanced Expansion of Regulatory CD8+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Pathologic Role and Temporal Appearance of Newly Emerging Autoepitopes in Relapsing Experimental Autoimmune Encephalomyelitis ¹

Carol L. Vanderlugt; Katherine L. Neville; Kelly M. Nikcevich; Todd N. Eagar; Jeffrey A. Bluestone; Stephen D. Miller

J Immunol (2000) 164 (2): 670–678.

Abstract

View articletitled, Pathologic Role and Temporal Appearance of Newly Emerging Autoepitopes in Relapsing Experimental Autoimmune Encephalomyelitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vanadate Induces Calcium Signaling, Ca²⁺ Release-Activated Ca²⁺ Channel Activation, and Gene Expression in T Lymphocytes and RBL-2H3 Mast Cells Via Thiol Oxidation ¹

George R. Ehring; Hubert H. Kerschbaum; Christopher M. Fanger; Claudia Eder; Heiko Rauer; Michael D. Cahalan

J Immunol (2000) 164 (2): 679–687.

Abstract

View articletitled, Vanadate Induces Calcium Signaling, Ca2+ Release-Activated Ca2+ Channel Activation, and Gene Expression in T Lymphocytes and RBL-2H3 Mast Cells Via Thiol Oxidation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Resting B Lymphocytes as APC for Naive T Lymphocytes: Dependence on CD40 Ligand/CD40 ¹

Dean E. Evans; Michael W. Munks; Jeffrey M. Purkerson; David C. Parker

J Immunol (2000) 164 (2): 688–697.

Abstract

View articletitled, Resting B Lymphocytes as APC for Naive T Lymphocytes: Dependence on CD40 Ligand/CD40<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vaccination with Mouse Mammary Adenocarcinoma Cells Coexpressing B7-1 (CD80) and B7-2 (CD86) Discloses the Dominant Effect of B7-1 in the Induction of Antitumor Immunity ¹

Alfonso Martín-Fontecha; Monica Moro; Maria Cristina Crosti; Fabrizio Veglia; Giulia Casorati; Paolo Dellabona

J Immunol (2000) 164 (2): 698–704.

Abstract

View articletitled, Vaccination with Mouse Mammary Adenocarcinoma Cells Coexpressing B7-1 (CD80) and B7-2 (CD86) Discloses the Dominant Effect of B7-1 in the Induction of Antitumor Immunity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Hierarchical Costimulator Thresholds for Distinct Immune Responses: Application of a Novel Two-Step Fc Fusion Protein Transfer Method ¹

Aoshuang Chen; Guoxing Zheng; Mark L. Tykocinski

J Immunol (2000) 164 (2): 705–711.

Abstract

View articletitled, Hierarchical Costimulator Thresholds for Distinct Immune Responses: Application of a Novel Two-Step Fc Fusion Protein Transfer Method<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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uPA/uPAR System Is Active in Immature Dendritic Cells Derived from CD14⁺CD34⁺ Precursors and Is Down-Regulated upon Maturation ¹

Elisabetta Ferrero; Katuscia Vettoretto; Attilio Bondanza; Antonello Villa; Massimo Resnati; Alessandro Poggi; Maria Raffaella Zocchi

J Immunol (2000) 164 (2): 712–718.

Abstract

View articletitled, uPA/uPAR System Is Active in Immature Dendritic Cells Derived from CD14+CD34+ Precursors and Is Down-Regulated upon Maturation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Effect of Molecular Size on the Ability of Zwitterionic Polysaccharides to Stimulate Cellular Immunity ¹

Wiltrud M. Kalka-Moll; Arthur O. Tzianabos; Ying Wang; Vincent J. Carey; Robert W. Finberg; Andrew B. Onderdonk; Dennis L. Kasper

J Immunol (2000) 164 (2): 719–724.

Abstract

View articletitled, Effect of Molecular Size on the Ability of Zwitterionic Polysaccharides to Stimulate Cellular Immunity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Soluble Antigen and CD40 Triggering Are Sufficient to Induce Primary and Memory Cytotoxic T Cells ¹

Leo Lefrançois; John D. Altman; Kristina Williams; Sara Olson

J Immunol (2000) 164 (2): 725–732.

Abstract

View articletitled, Soluble Antigen and CD40 Triggering Are Sufficient to Induce Primary and Memory Cytotoxic T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Defective Expression of the Monocyte Chemotactic Protein-1 Receptor CCR2 in Macrophages Associated with Human Ovarian Carcinoma ¹

Antonio Sica; Alessandra Saccani; Barbara Bottazzi; Sergio Bernasconi; Paola Allavena; Brancatelli Gaetano; Francesca Fei; Graig LaRosa; Chris Scotton; Frances Balkwill; Alberto Mantovani

J Immunol (2000) 164 (2): 733–738.

Abstract

View articletitled, Defective Expression of the Monocyte Chemotactic Protein-1 Receptor CCR2 in Macrophages Associated with Human Ovarian Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Comparative Contribution of CD1 on the Development of CD4⁺ and CD8⁺ T Cell Compartments ¹

Bin Wang; Taehoon Chun; Chyung-Ru Wang

J Immunol (2000) 164 (2): 739–745.

Abstract

View articletitled, Comparative Contribution of CD1 on the Development of CD4+ and CD8+ T Cell Compartments<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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α₄β₁ Integrin/VCAM-1 Interaction Activates α_Lβ₂ Integrin-Mediated Adhesion to ICAM-1 in Human T Cells ¹

Jason R. Chan; Sharon J. Hyduk; Myron I. Cybulsky

J Immunol (2000) 164 (2): 746–753.

Abstract

View articletitled, α4β1 Integrin/VCAM-1 Interaction Activates αLβ2 Integrin-Mediated Adhesion to ICAM-1 in Human T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Multidrug Resistance Protein 1: A Functionally Important Activation Marker for Murine Th1 Cells ¹

Stefan Prechtl; Martin Roellinghoff; Rik Scheper; Susan P. C. Cole; Roger G. Deeley; Michael Lohoff

J Immunol (2000) 164 (2): 754–761.

Abstract

View articletitled, The Multidrug Resistance Protein 1: A Functionally Important Activation Marker for Murine Th1 Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF-κB Activation in Tumor-Associated Macrophages ¹

Antonio Sica; Alessandra Saccani; Barbara Bottazzi; Nadia Polentarutti; Annunciata Vecchi; Jo Van Damme; Alberto Mantovani

J Immunol (2000) 164 (2): 762–767.

Abstract

View articletitled, Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF-κB Activation in Tumor-Associated Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1^−/− Mice ¹

U. Karrer; C. López-Macías; A. Oxenius; B. Odermatt; M. F. Bachmann; U. Kalinke; H. Bluethmann; H. Hengartner; R. M. Zinkernagel

J Immunol (2000) 164 (2): 768–778.

Abstract

View articletitled, Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1−/− Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ Is Necessary But Not Sufficient for Anti-CD40 Antibody-Mediated Inhibition of the Th2 Response to Schistosoma mansoni Eggs ¹

Diana L. Martin; Christopher L. King; Eric Pearlman; Ellen Strine; Frederick P. Heinzel

J Immunol (2000) 164 (2): 779–785.

Abstract

View articletitled, IFN-γ Is Necessary But Not Sufficient for Anti-CD40 Antibody-Mediated Inhibition of the Th2 Response to Schistosoma mansoni Eggs<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Renal Disease in MRL/lpr Mice Genetically Deficient in the Alternative Complement Pathway Factor B ¹

Hiroshi Watanabe; Gérard Garnier; Antonella Circolo; Rick A. Wetsel; Phil Ruiz; V. Michael Holers; Susan A. Boackle; Harvey R. Colten; Gary S. Gilkeson

J Immunol (2000) 164 (2): 786–794.

Abstract

View articletitled, Modulation of Renal Disease in MRL/lpr Mice Genetically Deficient in the Alternative Complement Pathway Factor B<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Comparison of Mouse and Rabbit Eiκ Enhancers Indicates That Different Elements Within the Enhancer May Mediate Activation of Transcription and Recombination ¹

Isabelle Coquilleau; Patricia Cavelier; François Rougeon; Michele Goodhardt

J Immunol (2000) 164 (2): 795–804.

Abstract

View articletitled, Comparison of Mouse and Rabbit Eiκ Enhancers Indicates That Different Elements Within the Enhancer May Mediate Activation of Transcription and Recombination<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Cytomegalovirus Gene Products US3 and US6 Down-Regulate Trophoblast Class I MHC Molecules ¹

Youngsoo Jun; Eunok Kim; Mirim Jin; Ha Chin Sung; Hoon Han; Daniel E. Geraghty; Kwangseog Ahn

J Immunol (2000) 164 (2): 805–811.

Abstract

View articletitled, Human Cytomegalovirus Gene Products US3 and US6 Down-Regulate Trophoblast Class I MHC Molecules<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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High-Level Rearrangement and Transcription of Yeast Artificial Chromosome-Based Mouse Igκ Transgenes Containing Distal Regions of the Contig ¹

Shuyu Li; Robert E. Hammer; Julia B. George-Raizen; Katherine C. Meyers; William T. Garrard

J Immunol (2000) 164 (2): 812–824.

Abstract

View articletitled, High-Level Rearrangement and Transcription of Yeast Artificial Chromosome-Based Mouse Igκ Transgenes Containing Distal Regions of the Contig<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Glucocorticoids Inhibit Calcium- and Calcineurin-Dependent Activation of the Human IL-4 Promoter ¹

Rongbing Chen; Thomas F. Burke; John E. Cumberland; Mary Brummet; Lisa A. Beck; Vincenzo Casolaro; Steve N. Georas

J Immunol (2000) 164 (2): 825–832.

Abstract

View articletitled, Glucocorticoids Inhibit Calcium- and Calcineurin-Dependent Activation of the Human IL-4 Promoter<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human CD8β, But Not Mouse CD8β, Can Be Expressed in the Absence of CD8α as a ββ Homodimer ¹

Lesley Devine; Lynda J. Kieffer; Victoria Aitken; Paula B. Kavathas

J Immunol (2000) 164 (2): 833–838.

Abstract

View articletitled, Human CD8β, But Not Mouse CD8β, Can Be Expressed in the Absence of CD8α as a ββ Homodimer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Disparate Intracellular Processing of Human IL-12 Preprotein Subunits: Atypical Processing of the P35 Signal Peptide ¹

Finbarr J. Murphy; Mark P. Hayes; Parris R. Burd

J Immunol (2000) 164 (2): 839–847.

Abstract

View articletitled, Disparate Intracellular Processing of Human IL-12 Preprotein Subunits: Atypical Processing of the P35 Signal Peptide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Cytoplasmic Tyrosine Motifs in Full-Length Glycoprotein 130 Have Different Roles in IL-6 Signal Transduction ¹

Jochen Schmitz; Heike Dahmen; Carsten Grimm; Cornelia Gendo; Gerhard Müller-Newen; Peter C. Heinrich; Fred Schaper

J Immunol (2000) 164 (2): 848–854.

Abstract

View articletitled, The Cytoplasmic Tyrosine Motifs in Full-Length Glycoprotein 130 Have Different Roles in IL-6 Signal Transduction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Involvement of mi-Transcription Factor in Expression of α-Melanocyte-Stimulating Hormone Receptor in Cultured Mast Cells of Mice ¹ ^²

Shiro Adachi; Eiichi Morii; Dae-ki Kim; Hideki Ogihara; Tomoko Jippo; Akihiko Ito; Young-Mi Lee; Yukihiko Kitamura

J Immunol (2000) 164 (2): 855–860.

Abstract

View articletitled, Involvement of mi-Transcription Factor in Expression of α-Melanocyte-Stimulating Hormone Receptor in Cultured Mast Cells of Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency ¹

Bernhard Hemmer; Clemencia Pinilla; Bruno Gran; Marco Vergelli; Nick Ling; Paul Conlon; Henry F. McFarland; Richard Houghten; Roland Martin

J Immunol (2000) 164 (2): 861–871.

Abstract

View articletitled, Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TNF-α Regulates Transforming Growth Factor-α Expression in Regenerating Murine Liver and Isolated Hepatocytes

Randle M. Gallucci; Petia P. Simeonova; Wataru Toriumi; Michael I. Luster

J Immunol (2000) 164 (2): 872–878.

Abstract

View articletitled, TNF-α Regulates Transforming Growth Factor-α Expression in Regenerating Murine Liver and Isolated Hepatocytes

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Evidence for a Stepwise Evolution of the CD3 Family ¹

Thomas W. F. Göbel; Jean-Pierre Dangy

J Immunol (2000) 164 (2): 879–883.

Abstract

View articletitled, Evidence for a Stepwise Evolution of the CD3 Family<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Transgenic Expression of Ly-49A in Thymocytes Alters Repertoire Selection ¹

Mary Pauza; Kathleen M. Smith; Heather Neal; Christina Reilly; Lewis L. Lanier; David Lo

J Immunol (2000) 164 (2): 884–892.

Abstract

View articletitled, Transgenic Expression of Ly-49A in Thymocytes Alters Repertoire Selection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Frequency and Characterization of Phenotypic Ig Heavy Chain Allelically Included IgM-Expressing B Cells in Mice ¹

Vasco Barreto; Ana Cumano

J Immunol (2000) 164 (2): 893–899.

Abstract

View articletitled, Frequency and Characterization of Phenotypic Ig Heavy Chain Allelically Included IgM-Expressing B Cells in Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Extension of HLA-A*0201-Restricted Minimal Epitope by N^ε-Palmitoyl-lysine Increases the Life Span of Functional Presentation to Cytotoxic T Cells ¹

Estelle Loing; Muriel Andrieu; Kader Thiam; Dominik Schörner; Karl-Heinz Wiesmüller; Anne Hosmalin; Günther Jung; Hélène Gras-Masse

J Immunol (2000) 164 (2): 900–907.

Abstract

View articletitled, Extension of HLA-A*0201-Restricted Minimal Epitope by Nε-Palmitoyl-lysine Increases the Life Span of Functional Presentation to Cytotoxic T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Bacterial Clearance and Survival Are Dependent on CXC Chemokine Receptor-2 Ligands in a Murine Model of Pulmonary Nocardia asteroides Infection ¹

Thomas A. Moore; Michael W. Newstead; Robert M. Strieter; Borna Mehrad; Blaine L. Beaman; Theodore J. Standiford

J Immunol (2000) 164 (2): 908–915.

Abstract

View articletitled, Bacterial Clearance and Survival Are Dependent on CXC Chemokine Receptor-2 Ligands in a Murine Model of Pulmonary Nocardia asteroides Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Type 1 and Type 2 CD8⁺ Effector T Cell Subpopulations Promote Long-Term Tumor Immunity and Protection to Progressively Growing Tumor ¹

Mark J. Dobrzanski; Joyce B. Reome; Richard W. Dutton

J Immunol (2000) 164 (2): 916–925.

Abstract

View articletitled, Type 1 and Type 2 CD8+ Effector T Cell Subpopulations Promote Long-Term Tumor Immunity and Protection to Progressively Growing Tumor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Decreased Cytomegalovirus Expression Following Proinflammatory Cytokine Treatment of Primary Human Astrocytes ¹

Maxim C.-J. Cheeran; Shuxian Hu; Genya Gekker; James R. Lokensgard

J Immunol (2000) 164 (2): 926–933.

Abstract

View articletitled, Decreased Cytomegalovirus Expression Following Proinflammatory Cytokine Treatment of Primary Human Astrocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Multiple Simian Immunodeficiency Virus (SIV)-Specific CTL Epitopes in Sooty Mangabeys with Natural and Experimentally Acquired SIV Infection ¹

Amitinder Kaur; Janet Yang; Donna Hempel; Linda Gritz; Gail P. Mazzara; Harold McClure; R. Paul Johnson

J Immunol (2000) 164 (2): 934–943.

Abstract

View articletitled, Identification of Multiple Simian Immunodeficiency Virus (SIV)-Specific CTL Epitopes in Sooty Mangabeys with Natural and Experimentally Acquired SIV Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells ¹

Gunther Hartmann; Arthur M. Krieg

J Immunol (2000) 164 (2): 944–953.

Abstract

View articletitled, Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ebola Virus Secretory Glycoprotein (sGP) Diminishes FcγRIIIB-to-CR3 Proximity on Neutrophils ¹

Andrei L. Kindzelskii; Zhi-yong Yang; Gary J. Nabel; Robert F. Todd, III; Howard R. Petty

J Immunol (2000) 164 (2): 953–958.

Abstract

View articletitled, Ebola Virus Secretory Glycoprotein (sGP) Diminishes FcγRIIIB-to-CR3 Proximity on Neutrophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activation of Human Neutrophils by Mycobacterium tuberculosis H37Ra Involves Phospholipase Cγ2, Shc Adapter Protein, and p38 Mitogen-Activated Protein Kinase ¹

Nasrin Perskvist; Limin Zheng; Olle Stendahl

J Immunol (2000) 164 (2): 959–965.

Abstract

View articletitled, Activation of Human Neutrophils by Mycobacterium tuberculosis H37Ra Involves Phospholipase Cγ2, Shc Adapter Protein, and p38 Mitogen-Activated Protein Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors ¹

Elke Cario; Ian M. Rosenberg; Steven L. Brandwein; Paul L. Beck; Hans-Christian Reinecker; Daniel K. Podolsky

J Immunol (2000) 164 (2): 966–972.

Abstract

View articletitled, Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CpG Oligonucleotides Can Prophylactically Immunize Against Th2-Mediated Schistosome Egg-Induced Pathology by an IL-12-Independent Mechanism ¹

Mónica G. Chiaramonte; Matthias Hesse; Allen W. Cheever; Thomas A. Wynn

J Immunol (2000) 164 (2): 973–985.

Abstract

View articletitled, CpG Oligonucleotides Can Prophylactically Immunize Against Th2-Mediated Schistosome Egg-Induced Pathology by an IL-12-Independent Mechanism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of CD4⁺ T Cell Responses During Natural Infection with Salmonella typhimurium¹

Stephen J. McSorley; Brad T. Cookson; Marc K. Jenkins

J Immunol (2000) 164 (2): 986–993.

Abstract

View articletitled, Characterization of CD4+ T Cell Responses During Natural Infection with Salmonella typhimurium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Compartmental Differences in NK Cell Responsiveness to IL-12 During Lymphocytic Choriomeningitis Virus Infection ¹

Gary C. Pien; Christine A. Biron

J Immunol (2000) 164 (2): 994–1001.

Abstract

View articletitled, Compartmental Differences in NK Cell Responsiveness to IL-12 During Lymphocytic Choriomeningitis Virus Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Vδ Repertoire During Thymic Ontogeny Suggests Three Novel Waves of γδ TCR Expression

Julia Weber-Arden; Oliver M. Wilbert; Dieter Kabelitz; Bernhard Arden

J Immunol (2000) 164 (2): 1002–1012.

Abstract

View articletitled, Vδ Repertoire During Thymic Ontogeny Suggests Three Novel Waves of γδ TCR Expression

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Inosine Inhibits Inflammatory Cytokine Production by a Posttranscriptional Mechanism and Protects Against Endotoxin-Induced Shock ¹

György Haskó; David G. Kuhel; Zoltán H. Németh; Jon G. Mabley; Robert F. Stachlewitz; László Virág; Zsolt Lohinai; Garry J. Southan; Andrew L. Salzman; Csaba Szabó

J Immunol (2000) 164 (2): 1013–1019.

Abstract

View articletitled, Inosine Inhibits Inflammatory Cytokine Production by a Posttranscriptional Mechanism and Protects Against Endotoxin-Induced Shock<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Human Neutrophil Responses to CD32 Cross-Linking by Serine/Threonine Phosphatase Inhibitors: Cross-Talk Between Serine/Threonine and Tyrosine Phosphorylation ¹

Emmanuelle Rollet-Labelle; Caroline Gilbert; Paul H. Naccache

J Immunol (2000) 164 (2): 1020–1028.

Abstract

View articletitled, Modulation of Human Neutrophil Responses to CD32 Cross-Linking by Serine/Threonine Phosphatase Inhibitors: Cross-Talk Between Serine/Threonine and Tyrosine Phosphorylation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cyclooxygenase-2-Derived Prostaglandin E₂ and Lipoxin A₄ Accelerate Resolution of Allergic Edema in Angiostrongylus costaricensis-Infected Rats: Relationship with Concurrent Eosinophilia ¹

Christianne Bandeira-Melo; Magda F. Serra; Bruno L. Diaz; Renato S. B. Cordeiro; Patricia M. R. Silva; Henrique L. Lenzi; Y. S. Bakhle; Charles N. Serhan; Marco A. Martins

J Immunol (2000) 164 (2): 1029–1036.

Abstract

View articletitled, Cyclooxygenase-2-Derived Prostaglandin E2 and Lipoxin A4 Accelerate Resolution of Allergic Edema in Angiostrongylus costaricensis-Infected Rats: Relationship with Concurrent Eosinophilia<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Macrophage Inflammatory Protein-2 Is a Mediator of Polymorphonuclear Neutrophil Influx in Ocular Bacterial Infection ¹

Karen A. Kernacki; Ronald P. Barrett; Jeffery A. Hobden; Linda D. Hazlett

J Immunol (2000) 164 (2): 1037–1045.

Abstract

View articletitled, Macrophage Inflammatory Protein-2 Is a Mediator of Polymorphonuclear Neutrophil Influx in Ocular Bacterial Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activation of Peroxisome Proliferator-Activated Receptor γ Does Not Inhibit IL-6 or TNF-α Responses of Macrophages to Lipopolysaccharide In Vitro or In Vivo

Rolf Thieringer; Judy E. Fenyk-Melody; Cheryl B. Le Grand; Beverly A. Shelton; Patricia A. Detmers; Elizabeth P. Somers; Linda Carbin; David E. Moller; Samuel D. Wright; Joel Berger

J Immunol (2000) 164 (2): 1046–1054.

Abstract

View articletitled, Activation of Peroxisome Proliferator-Activated Receptor γ Does Not Inhibit IL-6 or TNF-α Responses of Macrophages to Lipopolysaccharide In Vitro or In Vivo

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Molecular Analysis of CCR-3 Events in Eosinophilic Cells ¹

Nives Zimmermann; Bruce L. Daugherty; James M. Stark; Marc E. Rothenberg

J Immunol (2000) 164 (2): 1055–1064.

Abstract

View articletitled, Molecular Analysis of CCR-3 Events in Eosinophilic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Codominant Role of FcγRI/III and C5aR in the Reverse Arthus Reaction ¹

Ulrich Baumann; Jörg Köhl; Thomas Tschernig; Kirsten Schwerter-Strumpf; J. Sjef Verbeek; Reinhold E. Schmidt; J. Engelbert Gessner

J Immunol (2000) 164 (2): 1065–1070.

Abstract

View articletitled, A Codominant Role of FcγRI/III and C5aR in the Reverse Arthus Reaction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Glomerular Deposition of Immune Complexes Made with IgG2a Monoclonal Antibodies ¹

Melva L. Gonzalez; Frank J. Waxman

J Immunol (2000) 164 (2): 1071–1077.

Abstract

View articletitled, Glomerular Deposition of Immune Complexes Made with IgG2a Monoclonal Antibodies<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Decay-Accelerating Factor in Guinea Pig Stomachs Following Ischemia Reperfusion Stress ¹

Tadayuki Oshima; Noriko Okada; Takashi Joh; Makoto Sasaki; Toyohiro Tada; Noriyuki Matsukawa; Tomoyuki Nomura; Hirotaka Ohara; Makoto Itoh; Hidechika Okada

J Immunol (2000) 164 (2): 1078–1085.

Abstract

View articletitled, Decay-Accelerating Factor in Guinea Pig Stomachs Following Ischemia Reperfusion Stress<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Soluble IL-4 Receptor Inhibits Airway Inflammation Following Allergen Challenge in a Mouse Model of Asthma ¹

William R. Henderson, Jr.; Emil Y. Chi; Charles R. Maliszewski

J Immunol (2000) 164 (2): 1086–1095.

Abstract

View articletitled, Soluble IL-4 Receptor Inhibits Airway Inflammation Following Allergen Challenge in a Mouse Model of Asthma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Roles of IL-18 in Allergic Airway Disease: Induction of Eotaxin by Resident Cell Populations Exacerbates Eosinophil Accumulation ¹

Emma Campbell; Steven L. Kunkel; Robert M. Strieter; Nicholas W. Lukacs

J Immunol (2000) 164 (2): 1096–1102.

Abstract

View articletitled, Differential Roles of IL-18 in Allergic Airway Disease: Induction of Eotaxin by Resident Cell Populations Exacerbates Eosinophil Accumulation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Myelin-Associated Oligodendrocytic Basic Protein: Identification of an Encephalitogenic Epitope and Association with Multiple Sclerosis ¹

Andreas Holz; Bibiana Bielekova; Roland Martin; Michael B. A. Oldstone

J Immunol (2000) 164 (2): 1103–1109.

Abstract

View articletitled, Myelin-Associated Oligodendrocytic Basic Protein: Identification of an Encephalitogenic Epitope and Association with Multiple Sclerosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rheumatoid Arthritis Synovial Stromal Cells Inhibit Apoptosis and Up-Regulate Bcl-x_L Expression by B Cells in a CD49/CD29-CD106-Dependent Mechanism ¹

Kenji Hayashida; Yasunori Shimaoka; Takahiro Ochi; Peter E Lipsky

J Immunol (2000) 164 (2): 1110–1116.

Abstract

View articletitled, Rheumatoid Arthritis Synovial Stromal Cells Inhibit Apoptosis and Up-Regulate Bcl-xL Expression by B Cells in a CD49/CD29-CD106-Dependent Mechanism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Therapeutic Potential of Phosphodiesterase-4 and -3 Inhibitors in Th1-Mediated Autoimmune Diseases

Bibiana Bielekova; Anne Lincoln; Henry McFarland; Roland Martin

J Immunol (2000) 164 (2): 1117–1124.

Abstract

View articletitled, Therapeutic Potential of Phosphodiesterase-4 and -3 Inhibitors in Th1-Mediated Autoimmune Diseases

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Induction of Potent Antitumor CTL Responses by Recombinant Vaccinia Encoding a Melan-A Peptide Analogue

Danila Valmori; Frederic Lévy; Isabelle Miconnet; Paul Zajac; Giulio C. Spagnoli; Donata Rimoldi; Danielle Liénard; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero

J Immunol (2000) 164 (2): 1125–1131.

Abstract

View articletitled, Induction of Potent Antitumor CTL Responses by Recombinant Vaccinia Encoding a Melan-A Peptide Analogue

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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