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CUTTING EDGE

Cutting Edge: Recombinase-Activating Gene Expression and V(D)J Recombination in CD4⁺CD3^low Mature T Lymphocytes ¹

Erica Lantelme; Belinda Palermo; Luisa Granziero; Stefania Mantovani; Rita Campanelli; Virginia Monafo; Antonio Lanzavecchia; Claudia Giachino

J Immunol (2000) 164 (7): 3455–3459.

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Cutting Edge: Identification of the Orphan Receptor G-Protein-Coupled Receptor 2 as CCR10, a Specific Receptor for the Chemokine ESkine ¹ ^²

David I. Jarmin; Miriam Rits; Dalena Bota; Norma P. Gerard; Gerard J. Graham; Ian Clark-Lewis; Craig Gerard

J Immunol (2000) 164 (7): 3460–3464.

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Cutting Edge: The Orphan Chemokine Receptor G Protein-Coupled Receptor-2 (GPR-2, CCR10) Binds the Skin-Associated Chemokine CCL27 (CTACK/ALP/ILC)¹

Bernhard Homey; Wei Wang; Hortensia Soto; Matthew E. Buchanan; Andrea Wiesenborn; Daniel Catron; Anja Müller; Terrill K. McClanahan; Marie-Caroline Dieu-Nosjean; Rocio Orozco; Thomas Ruzicka; Percy Lehmann; Elizabeth Oldham; Albert Zlotnik

J Immunol (2000) 164 (7): 3465–3470.

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Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages ¹

Sachiko Akashi; Rintaro Shimazu; Hirotaka Ogata; Yoshinori Nagai; Kiyoshi Takeda; Masao Kimoto; Kensuke Miyake

J Immunol (2000) 164 (7): 3471–3475.

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Cutting Edge: Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression ¹

Fumiko Nomura; Sachiko Akashi; Yoshimitsu Sakao; Shintaro Sato; Taro Kawai; Makoto Matsumoto; Kenji Nakanishi; Masao Kimoto; Kensuke Miyake; Kiyoshi Takeda; Shizuo Akira

J Immunol (2000) 164 (7): 3476–3479.

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Cutting Edge: Human B Cell Function Is Regulated by Interaction with Soluble CD14: Opposite Effects on IgG1 and IgE Production ¹

Mauricio A. Arias; Julia E. Rey Nores; Natalio Vita; Felix Stelter; Leszek K. Borysiewicz; Pascual Ferrara; Mario O. Labéta

J Immunol (2000) 164 (7): 3480–3486.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

IL-4 Diminishes Perforin-Mediated and Increases Fas Ligand-Mediated Cytotoxicity In Vivo ¹

Sandra Aung; Barney S. Graham

J Immunol (2000) 164 (7): 3487–3493.

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Calcitonin Gene-Related Peptide Decreases Expression of HLA-DR and CD86 by Human Dendritic Cells and Dampens Dendritic Cell-Driven T Cell-Proliferative Responses Via the Type I Calcitonin Gene-Related Peptide Receptor ¹

John A. Carucci; Ralf Ignatius; Yang Wei; Aaron M. Cypess; David A. Schaer; Melissa Pope; Ralph M. Steinman; Svetlana Mojsov

J Immunol (2000) 164 (7): 3494–3499.

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IL-2 and IL-15 Regulate CD154 Expression on Activated CD4 T Cells ¹

Søren Skov; Mark Bonyhadi; Niels Ødum; Jeffrey A. Ledbetter

J Immunol (2000) 164 (7): 3500–3505.

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Ligand-Independent Down-Regulation of IFN-γ Receptor 1 Following TCR Engagement ¹

Heidi Skrenta; Yang Yang; Sidney Pestka; C. Garrison Fathman

J Immunol (2000) 164 (7): 3506–3511.

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The IFN Regulatory Factor Family Participates in Regulation of Fas Ligand Gene Expression in T Cells

Warren A. Chow; Jing Jing Fang; Jiing-Kuan Yee

J Immunol (2000) 164 (7): 3512–3518.

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Positive Selection Is Limited by Available Peptide-Dependent MHC Conformations ¹

Heather E. Stefanski; Stephen C. Jameson; Kristin A. Hogquist

J Immunol (2000) 164 (7): 3519–3526.

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Regulation of Lymphoid Homeostasis by IL-2 Receptor Signals In Vivo ¹

Danny T. M. Leung; Samantha Morefield; Dennis M. Willerford

J Immunol (2000) 164 (7): 3527–3534.

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Identification of a MHC Class II-Restricted Human gp100 Epitope Using DR4-IE Transgenic Mice

Christopher E. Touloukian; Wolfgang W. Leitner; Suzanne L. Topalian; Yong F. Li; Paul F. Robbins; Steven A. Rosenberg; Nicholas P. Restifo

J Immunol (2000) 164 (7): 3535–3542.

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The Role of B7 Costimulation in CD4/CD8 T Cell Homeostasis

Xiang Yu; Sylvie Fournier; James P. Allison; Arlene H. Sharpe; Richard J. Hodes

J Immunol (2000) 164 (7): 3543–3553.

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Polarization of Naive CD4⁺ T Cells Toward the Th1 Subset by CTLA-4 Costimulation ¹

Takuma Kato; Hideo Nariuchi

J Immunol (2000) 164 (7): 3554–3562.

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IL-4, IL-10, IL-13, and TGF-β from an Altered Peptide Ligand-Specific Th2 Cell Clone Down-Regulate Adoptive Transfer of Experimental Autoimmune Encephalomyelitis

Deborah A. Young; Leslie D. Lowe; Susan S. Booth; Matthew J. Whitters; Lindsay Nicholson; Vijay K. Kuchroo; Mary Collins

J Immunol (2000) 164 (7): 3563–3572.

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Regulatory CD4 T Cells Control the Size of the Peripheral Activated/Memory CD4 T Cell Compartment ¹

Oliver Annacker; Odile Burlen-Defranoux; Ricardo Pimenta-Araujo; Ana Cumano; Antonio Bandeira

J Immunol (2000) 164 (7): 3573–3580.

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Targeting Rare Populations of Murine Antigen-Specific T Lymphocytes by Retroviral Transduction for Potential Application in Gene Therapy for Autoimmune Disease ¹

Gina L. Costa; Jacqueline M. Benson; Christine M. Seroogy; Philip Achacoso; C. Garrison Fathman; Garry P. Nolan

J Immunol (2000) 164 (7): 3581–3590.

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Coordinate Regulation of T Cell Activation by CD2 and CD28 ¹

Jonathan M. Green; Vladimir Karpitskiy; Stephanie L. Kimzey; Andrey S. Shaw

J Immunol (2000) 164 (7): 3591–3595.

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Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation

Patrick Hwu; Mark X. Du; Réjean Lapointe; My Do; Milton W. Taylor; Howard A. Young

J Immunol (2000) 164 (7): 3596–3599.

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Large-Scale Culture and Selective Maturation of Human Langerhans Cells from Granulocyte Colony-Stimulating Factor-Mobilized CD34⁺ Progenitors ¹

Evelina Gatti; Mark A. Velleca; Barbara C. Biedermann; Weilie Ma; Juli Unternaehrer; Melanie W. Ebersold; Ruslan Medzhitov; Jordan S. Pober; Ira Mellman

J Immunol (2000) 164 (7): 3600–3607.

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IL-15 Is Highly Expressed in Inflammatory Bowel Disease and Regulates Local T Cell-Dependent Cytokine Production ¹

Zhanju Liu; Karel Geboes; Stefaan Colpaert; Geert R. D’Haens; Paul Rutgeerts; Jan L. Ceuppens

J Immunol (2000) 164 (7): 3608–3615.

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Role of Gut Cryptopatches in Early Extrathymic Maturation of Intestinal Intraepithelial T Cells ¹

Takatoku Oida; Kenji Suzuki; Masanobu Nanno; Yutaka Kanamori; Hisashi Saito; Eiro Kubota; Shingo Kato; Mamoru Itoh; Shuichi Kaminogawa; Hiromichi Ishikawa

J Immunol (2000) 164 (7): 3616–3626.

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Anti-LFA-1 Therapy Induces Long-Term Islet Allograft Acceptance in the Absence of IFN-γ or IL-4 ¹

Mark R. Nicolls; Marilyne Coulombe; Huan Yang; Amy Bolwerk; Ronald G. Gill

J Immunol (2000) 164 (7): 3627–3634.

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Analysis of Signals and Functions of the Chimeric Human Granuloctye-Macrophage Colony-Stimulating Factor Receptor in BA/F3 Cells and Transgenic Mice

Sumiko Watanabe; Yutaka Aoki; Ichiko Nishijima; Ming-jiang Xu; Ken-ichi Arai

J Immunol (2000) 164 (7): 3635–3644.

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Crucial Role of TNF-α in CD8 T Cell-Mediated Elimination of 3LL-A9 Lewis Lung Carcinoma Cells In Vivo ¹

Armelle Prévost-Blondel; Evelyn Roth; Felicia M. Rosenthal; Hanspeter Pircher

J Immunol (2000) 164 (7): 3645–3651.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

SHPS-1 Induces Aggregation of Ba/F3 Pro-B Cells Via an Interaction with CD47 ¹

Ivan Babic; Annette Schallhorn; Frederik P. Lindberg; Frank R. Jirik

J Immunol (2000) 164 (7): 3652–3658.

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Correct Immunoglobulin α mRNA Processing Depends on Specific Sequence in the C_α3-αM Intron ¹

John H. Coyle; Deborah A. Lebman

J Immunol (2000) 164 (7): 3659–3665.

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Novel Mutations Within the RFX-B Gene and Partial Rescue of MHC and Related Genes Through Exogenous Class II Transactivator in RFX-B-Deficient Cells ¹

Uma M. Nagarajan; Ad Peijnenburg; Sam J. P. Gobin; Jeremy M. Boss; Peter J. van den Elsen

J Immunol (2000) 164 (7): 3666–3674.

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HOST DEFENSE

p53-Dependent and -Independent Pathways of Apoptotic Cell Death in Sepsis ¹

Richard S. Hotchkiss; Kevin W. Tinsley; Jia-Ji Hui; Katherine C. Chang; Paul E. Swanson; Anne M. Drewry; Timothy G. Buchman; Irene E. Karl

J Immunol (2000) 164 (7): 3675–3680.

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B Cell-Deficient Mice Are Highly Resistant to Leishmania donovani Infection, but Develop Neutrophil-Mediated Tissue Pathology ¹

Sara C. Smelt; Sara E. J. Cotterell; Christian R. Engwerda; Paul M. Kaye

J Immunol (2000) 164 (7): 3681–3688.

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Role of CD40 Ligand and CD28 in Induction and Maintenance of Antiviral CD8⁺ Effector T Cell Responses ¹

Susanne Ørding Andreasen; Jeanette Erbo Christensen; Ole Marker; Allan Randrup Thomsen

J Immunol (2000) 164 (7): 3689–3697.

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Neonatal Administration of IL-12 Enhances the Protective Efficacy of Antiviral Vaccines ¹

Bernard P. Arulanandam; James N. Mittler; William T. Lee; Margot O’Toole; Dennis W. Metzger

J Immunol (2000) 164 (7): 3698–3704.

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Redirected Perforin-Dependent Lysis of Colon Carcinoma by Ex Vivo Genetically Engineered CTL ¹

Phillip K. Darcy; Nicole M. Haynes; Marie B. Snook; Joseph A. Trapani; Loretta Cerruti; Stephen M. Jane; Mark J. Smyth

J Immunol (2000) 164 (7): 3705–3712.

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Survival of Staphylococcus aureus Inside Neutrophils Contributes to Infection ¹

Hattie D. Gresham; Jon H. Lowrance; Tony E. Caver; Bridget S. Wilson; Ambrose L. Cheung; Frederik P. Lindberg

J Immunol (2000) 164 (7): 3713–3722.

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Direct Visualization of Cytokine-Producing Recall Antigen-Specific CD4 Memory T Cells in Healthy Individuals and HIV Patients ¹

Thomas Helms; Bernhard O. Boehm; Robert J. Asaad; R. P. Trezza; Paul V. Lehmann; Magdalena Tary-Lehmann

J Immunol (2000) 164 (7): 3723–3732.

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Lactobacilli and Streptococci Activate NF-κB and STAT Signaling Pathways in Human Macrophages ¹

Minja Miettinen; Anne Lehtonen; Ilkka Julkunen; Sampsa Matikainen

J Immunol (2000) 164 (7): 3733–3740.

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T Cell Clones Raised from Chronically Infected Healthy Humans by Stimulation with Toxoplasma gondii Excretory-Secretory Antigens Cross-React with Live Tachyzoites: Characterization of the Fine Antigenic Specificity of the Clones and Implications for Vaccine Development ¹

Ignazia Prigione; Paola Facchetti; Laurence Lecordier; Didier Deslée; Sabrina Chiesa; Marie-France Cesbron-Delauw; Vito Pistoia

J Immunol (2000) 164 (7): 3741–3748.

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A Role of Mast Cell Glycosaminoglycans for the Immunological Expulsion of Intestinal Nematode, Strongyloides venezuelensis¹

Haruhiko Maruyama; Yoshisada Yabu; Ayako Yoshida; Yukifumi Nawa; Nobuo Ohta

J Immunol (2000) 164 (7): 3749–3754.

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Isolated Pneumocystis carinii Cell Wall Glucan Provokes Lower Respiratory Tract Inflammatory Responses ¹

Robert Vassallo; Joseph E. Standing; Andrew H. Limper

J Immunol (2000) 164 (7): 3755–3763.

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Resistance Against the Membrane Attack Complex of Complement Induced in Porcine Endothelial Cells with a Galα(1–3)Gal Binding Lectin: Up-Regulation of CD59 Expression ¹

Agustin P. Dalmasso; Barbara A. Benson; Jason S. Johnson; Cheryl Lancto; Mitchell S. Abrahamsen

J Immunol (2000) 164 (7): 3764–3773.

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Identification of Unique Truncated KC/GROβ Chemokines with Potent Hematopoietic and Anti-Infective Activities

Andrew G. King; Kyung Johanson; Carrie L. Frey; Peter L. DeMarsh; John R. White; Patrick McDevitt; Dean McNulty; Joanna Balcarek; Zdenka L. Jonak; Pradip K. Bhatnagar; Louis M. Pelus

J Immunol (2000) 164 (7): 3774–3782.

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Characterization of Synthetic C3a Analog Peptides on Human Eosinophils in Comparison to the Native Complement Component C3a ¹

Holger Petering; Jörg Köhl; Ansgar Weyergraf; Yasmin Dulkys; Daniela Kimmig; Regina Smolarski; Alexander Kapp; Jörn Elsner

J Immunol (2000) 164 (7): 3783–3789.

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INFLAMMATION

Aerosolized Syk Antisense Suppresses Syk Expression, Mediator Release from Macrophages, and Pulmonary Inflammation ¹

Grant R. Stenton; Moo-Kyung Kim; Osamu Nohara; Chin-Fu Chen; Nadir Hirji; Fiona L. Wills; Mark Gilchrist; Pyoung-Han Hwang; Jong-Gu Park; Warren Finlay; Richard L. Jones; A. Dean Befus; Alan D. Schreiber

J Immunol (2000) 164 (7): 3790–3797.

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Shear and Time-Dependent Changes in Mac-1, LFA-1, and ICAM-3 Binding Regulate Neutrophil Homotypic Adhesion ¹

Sriram Neelamegham; Andrew D. Taylor; Harish Shankaran; C. Wayne Smith; Scott I. Simon

J Immunol (2000) 164 (7): 3798–3805.

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Cultured Human Fibroblasts Express Constitutive IL-16 mRNA: Cytokine Induction of Active IL-16 Protein Synthesis Through a Caspase-3-Dependent Mechanism ¹

Daniela Sciaky; William Brazer; David M. Center; William W. Cruikshank; Terry J. Smith

J Immunol (2000) 164 (7): 3806–3814.

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Regulation of the RON Receptor Tyrosine Kinase Expression in Macrophages: Blocking the RON Gene Transcription by Endotoxin-Induced Nitric Oxide ¹ ^²

Ming-Hai Wang; Hai-Lin Fung; Yi-Qing Chen

J Immunol (2000) 164 (7): 3815–3821.

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Polymorphonuclear Leukocytes Modulate Tissue Factor Production by Mononuclear Cells: Role of Reactive Oxygen Species

Yves Cadroy; Dominique Dupouy; Bernard Boneu; Henri Plaisancié

J Immunol (2000) 164 (7): 3822–3828.

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Vav Synergizes with Protein Kinase CΘ to Mediate IL-4 Gene Expression in Response to CD28 Costimulation in T Cells ¹

Steffen P. Hehner; Min Li-Weber; Marco Giaisi; Wulf Dröge; Peter H. Krammer; M. Lienhard Schmitz

J Immunol (2000) 164 (7): 3829–3836.

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IL-11 Activates Human Endothelial Cells to Resist Immune-Mediated Injury

Keyvan Mahboubi; Barbara C. Biedermann; Joseph M. Carroll; Jordan S. Pober

J Immunol (2000) 164 (7): 3837–3846.

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Migration of Eosinophils Across Endothelial Cell Monolayers: Interactions Among IL-5, Endothelial-Activating Cytokines, and C-C Chemokines ¹

Syed Shahabuddin; Paul Ponath; Robert P. Schleimer

J Immunol (2000) 164 (7): 3847–3854.

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An Essential Role of Mast Cells in the Development of Airway Hyperresponsiveness in a Murine Asthma Model

Tetsuto Kobayashi; Toru Miura; Tomoko Haba; Miyuki Sato; Isao Serizawa; Hiroichi Nagai; Kimishige Ishizaka

J Immunol (2000) 164 (7): 3855–3861.

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Induction of Functional IL-8 Receptors by IL-4 and IL-13 in Human Monocytes ¹

Raffaella Bonecchi; Fabio Facchetti; Stefano Dusi; Walter Luini; Daniele Lissandrini; Marleen Simmelink; Massimo Locati; Sergio Bernasconi; Paola Allavena; Ernst Brandt; Filippo Rossi; Alberto Mantovani; Silvano Sozzani

J Immunol (2000) 164 (7): 3862–3869.

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G551D Cystic Fibrosis Mice Exhibit Abnormal Regulation of Inflammation in Lungs and Macrophages ¹

Gordon R. Thomas; Elaine A. Costelloe; Dominic P. Lunn; Katryn J. Stacey; Steven J. Delaney; Robert Passey; Edwina C. McGlinn; Brendan J. McMorran; Azita Ahadizadeh; Carolyn L. Geczy; Brandon J. Wainwright; David A. Hume

J Immunol (2000) 164 (7): 3870–3877.

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Alveolar Macrophages Bind and Phagocytose Allergen- Containing Pollen Starch Granules Via C-Type Lectin and Integrin Receptors: Implications for Airway Inflammatory Disease ¹

Andrew J. Currie; Geoffrey A. Stewart; Andrew S. McWilliam

J Immunol (2000) 164 (7): 3878–3886.

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CLINICAL IMMUNOLOGY

Granuloctye-Macrophage Colony-Stimulating Factor as an Autocrine Survival Factor for Mature Normal and Malignant B Lymphocytes ¹

Robert J. Harris; Andrew R. Pettitt; Caroline Schmutz; Paul D. Sherrington; Mirko Zuzel; John C. Cawley; Stephen D. Griffiths

J Immunol (2000) 164 (7): 3887–3893.

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Activation of the IL-4 STAT Pathway in Rheumatoid Synovium ¹

Ulf Müller-Ladner; Martin Judex; Wibke Ballhorn; Frank Kullmann; Oliver Distler; Klaus Schlottmann; Renate E. Gay; Jürgen Schölmerich; Steffen Gay

J Immunol (2000) 164 (7): 3894–3901.

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Tumor-Specific CD4⁺ T Lymphocytes from Cancer Patients Are Required for Optimal Induction of Cytotoxic T Cells Against the Autologous Tumor

Constantin N. Baxevanis; Ioannis F. Voutsas; Ourania E. Tsitsilonis; Angelos D. Gritzapis; Roula Sotiriadou; Michael Papamichail

J Immunol (2000) 164 (7): 3902–3912.

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Identification of a CD8 T Cell That Can Independently Mediate Autoimmune Diabetes Development in the Complete Absence of CD4 T Cell Helper Functions ¹

Robert T. Graser; Teresa P. DiLorenzo; Fuming Wang; Gregory J. Christianson; Harold D. Chapman; Derry C. Roopenian; Stanley G. Nathenson; David V. Serreze

J Immunol (2000) 164 (7): 3913–3918.

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Protection of Nonobese Diabetic Mice from Diabetes by Gene(s) Closely Linked to IFN-γ Receptor Loci ¹

Osami Kanagawa; Guan Xu; Amye Tevaarwerk; Barbara A. Vaupel

J Immunol (2000) 164 (7): 3919–3923.

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Reduced Chemokine and Chemokine Receptor Expression in Spinal Cords of TCR BV8S2 Transgenic Mice Protected Against Experimental Autoimmune Encephalomyelitis with BV8S2 Protein ¹

Agata Matejuk; Arthur A. Vandenbark; Gregory G. Burrows; Bruce F. Bebo, Jr.; Halina Offner

J Immunol (2000) 164 (7): 3924–3931.

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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