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CUTTING EDGE

Cutting Edge: CD4 Is Not Required for the Functional Activity of IL-16 ¹

Nathalie L. Mathy; Norbert Bannert; Stephen G. Norley; Reinhard Kurth

J Immunol (2000) 164 (9): 4429–4432.

Abstract

View articletitled, Cutting Edge: CD4 Is Not Required for the Functional Activity of IL-16<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Blockade of T Cell Activation Using a Surface-Linked Single-Chain Antibody to CTLA-4 (CD152)¹

Matthew D. Griffin; David K. Hong; Philmore O. Holman; Kyung-Mi Lee; Matthew J. Whitters; Sean M. O’Herrin; Francesca Fallarino; Mary Collins; David M. Segal; Thomas F. Gajewski; David M. Kranz; Jeffrey A. Bluestone

J Immunol (2000) 164 (9): 4433–4442.

Abstract

View articletitled, Blockade of T Cell Activation Using a Surface-Linked Single-Chain Antibody to CTLA-4 (CD152)<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vitamin D₃ Affects Differentiation, Maturation, and Function of Human Monocyte-Derived Dendritic Cells ¹

Lorenzo Piemonti; Paolo Monti; Marina Sironi; Paolo Fraticelli; Biagio Eugenio Leone; Elena Dal Cin; Paola Allavena; Valerio Di Carlo

J Immunol (2000) 164 (9): 4443–4451.

Abstract

View articletitled, Vitamin D3 Affects Differentiation, Maturation, and Function of Human Monocyte-Derived Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Donor MHC Class II Antigen Is Essential for Induction of Transplantation Tolerance by Bone Marrow Cells ¹

Akihisa Umemura; Anthony P. Monaco; Takashi Maki

J Immunol (2000) 164 (9): 4452–4457.

Abstract

View articletitled, Donor MHC Class II Antigen Is Essential for Induction of Transplantation Tolerance by Bone Marrow Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Analysis of Human Vα24⁺ CD4⁺ NKT Cells Activated by α-Glycosylceramide-Pulsed Monocyte-Derived Dendritic Cells

Tsuyoshi Takahashi; Mie Nieda; Yasuhiko Koezuka; Andrew Nicol; Steven A. Porcelli; Yoshihide Ishikawa; Kenji Tadokoro; Hisamaru Hirai; Takeo Juji

J Immunol (2000) 164 (9): 4458–4464.

Abstract

View articletitled, Analysis of Human Vα24+ CD4+ NKT Cells Activated by α-Glycosylceramide-Pulsed Monocyte-Derived Dendritic Cells

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The Roles of CD28 and CD40 Ligand in T Cell Activation and Tolerance ¹

Kimberly C. Howland; Lara J. Ausubel; Cheryl A. London; Abul K. Abbas

J Immunol (2000) 164 (9): 4465–4470.

Abstract

View articletitled, The Roles of CD28 and CD40 Ligand in T Cell Activation and Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Regulation of CD95 (Fas) Ligand Expression in Primary T Cells: Induction of Promoter Activation in CD95LP-Luc Transgenic Mice ¹

Lyse A. Norian; Kevin M. Latinis; Steve L. Eliason; Krzysztof Lyson; Chunmei Yang; Timothy Ratliff; Gary A. Koretzky

J Immunol (2000) 164 (9): 4471–4480.

Abstract

View articletitled, The Regulation of CD95 (Fas) Ligand Expression in Primary T Cells: Induction of Promoter Activation in CD95LP-Luc Transgenic Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Astrocyte-Targeted Expression of IL-12 Induces Active Cellular Immune Responses in the Central Nervous System and Modulates Experimental Allergic Encephalomyelitis ¹

Axel Pagenstecher; Silke Lassmann; Monica J. Carson; Carrie L. Kincaid; Anna K. Stalder; Iain L. Campbell

J Immunol (2000) 164 (9): 4481–4492.

Abstract

View articletitled, Astrocyte-Targeted Expression of IL-12 Induces Active Cellular Immune Responses in the Central Nervous System and Modulates Experimental Allergic Encephalomyelitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Delayed and Separate Costimulation In Vitro Supports the Evidence of a Transient “Excited” State of CD8⁺ T Cells During Activation

Nathalie Pardigon; Christophe Cambouris; Nadège Bercovici; Fabrice Lemaı̂tre; Roland Liblau; Philippe Kourilsky

J Immunol (2000) 164 (9): 4493–4499.

Abstract

View articletitled, Delayed and Separate Costimulation In Vitro Supports the Evidence of a Transient “Excited” State of CD8+ T Cells During Activation

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MHC Class I Antigen Processing of an Adenovirus CTL Epitope Is Linked to the Levels of Immunoproteasomes in Infected Cells ¹

Alice J. A. M. Sijts; Sybille Standera; René E. M. Toes; Thomas Ruppert; Nico J. C. M. Beekman; Peter A. van Veelen; Ferry A. Ossendorp; Cornelis J. M. Melief; Peter M. Kloetzel

J Immunol (2000) 164 (9): 4500–4506.

Abstract

View articletitled, MHC Class I Antigen Processing of an Adenovirus CTL Epitope Is Linked to the Levels of Immunoproteasomes in Infected Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Development of Th1-Inducing Capacity in Myeloid Dendritic Cells Requires Environmental Instruction ¹

Pedro L. Vieira; Esther C. de Jong; Eddy A. Wierenga; Martien L. Kapsenberg; Paweł Kaliński

J Immunol (2000) 164 (9): 4507–4512.

Abstract

View articletitled, Development of Th1-Inducing Capacity in Myeloid Dendritic Cells Requires Environmental Instruction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evidence of Selective Processing of Immunodominant Epitopes in Virally Infected Cells ¹

Qian-Jin Zhang; Susan S. Chen; Carol-Ann Saari; Maria G. Massuci; Frank Tufaro; Wilfred A. Jefferies

J Immunol (2000) 164 (9): 4513–4521.

Abstract

View articletitled, Evidence of Selective Processing of Immunodominant Epitopes in Virally Infected Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Humoral Immune Responses in Cr2^−/− Mice: Enhanced Affinity Maturation but Impaired Antibody Persistence ¹

Zhibin Chen; Sergei B. Koralov; Mariya Gendelman; Michael C. Carroll; Garnett Kelsoe

J Immunol (2000) 164 (9): 4522–4532.

Abstract

View articletitled, Humoral Immune Responses in Cr2−/− Mice: Enhanced Affinity Maturation but Impaired Antibody Persistence<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Crry/p65, a Membrane Complement Regulatory Protein, Has Costimulatory Properties on Mouse T Cells ¹

Elena Fernández-Centeno; Gloria de Ojeda; José M. Rojo; Pilar Portolés

J Immunol (2000) 164 (9): 4533–4542.

Abstract

View articletitled, Crry/p65, a Membrane Complement Regulatory Protein, Has Costimulatory Properties on Mouse T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vivo Behavior of Peptide-Specific T Cells During Mucosal Tolerance Induction: Antigen Introduced Through the Mucosa of the Conjunctiva Elicits Prolonged Antigen-Specific T Cell Priming Followed by Anergy ¹

Rita M. Egan; Chris Yorkey; Richard Black; Wai Khan Loh; Julia L. Stevens; Eugene Storozynsky; Edith M. Lord; John G. Frelinger; Jerold G. Woodward

J Immunol (2000) 164 (9): 4543–4550.

Abstract

View articletitled, In Vivo Behavior of Peptide-Specific T Cells During Mucosal Tolerance Induction: Antigen Introduced Through the Mucosa of the Conjunctiva Elicits Prolonged Antigen-Specific T Cell Priming Followed by Anergy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antigen-Experienced CD4 T Cells Display a Reduced Capacity for Clonal Expansion In Vivo That Is Imposed by Factors Present in the Immune Host ¹

Rebecca Merica; Alexander Khoruts; Kathryn A. Pape; R. Lee Reinhardt; Marc K. Jenkins

J Immunol (2000) 164 (9): 4551–4557.

Abstract

View articletitled, Antigen-Experienced CD4 T Cells Display a Reduced Capacity for Clonal Expansion In Vivo That Is Imposed by Factors Present in the Immune Host<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Secondary Lymphoid Tissue Chemokine Mediates T Cell-Dependent Antitumor Responses In Vivo ¹

Sherven Sharma; Marina Stolina; Jie Luo; Robert M. Strieter; Marie Burdick; Li X. Zhu; Raj K. Batra; Steven M. Dubinett

J Immunol (2000) 164 (9): 4558–4563.

Abstract

View articletitled, Secondary Lymphoid Tissue Chemokine Mediates T Cell-Dependent Antitumor Responses In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD28-Specific Antibody Prevents Graft-Versus-Host Disease in Mice ¹

Xue-Zhong Yu; Sasha J. Bidwell; Paul J. Martin; Claudio Anasetti

J Immunol (2000) 164 (9): 4564–4568.

Abstract

View articletitled, CD28-Specific Antibody Prevents Graft-Versus-Host Disease in Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Faithful Expression of the Human 5q31 Cytokine Cluster in Transgenic Mice ¹

Dee A. Lacy; Zhi-En Wang; Derek J. Symula; Clifford J. McArthur; Edward M. Rubin; Kelly A. Frazer; Richard M. Locksley

J Immunol (2000) 164 (9): 4569–4574.

Abstract

View articletitled, Faithful Expression of the Human 5q31 Cytokine Cluster in Transgenic Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-2 Signaling in Human Monocytes Involves the Phosphorylation and Activation of p59^{hck 1}

Maria C. Bosco; Rafael E. Curiel; Arnold H. Zea; Maria G. Malabarba; John R. Ortaldo; Igor Espinoza-Delgado

J Immunol (2000) 164 (9): 4575–4585.

Abstract

View articletitled, IL-2 Signaling in Human Monocytes Involves the Phosphorylation and Activation of p59hck 1

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A V_H11V_κ9 B Cell Antigen Receptor Drives Generation of CD5⁺ B Cells Both In Vivo and In Vitro ¹

Michael J. Chumley; Joseph M. Dal Porto; Susumu Kawaguchi; John C. Cambier; David Nemazee; Richard R. Hardy

J Immunol (2000) 164 (9): 4586–4593.

Abstract

View articletitled, A VH11Vκ9 B Cell Antigen Receptor Drives Generation of CD5+ B Cells Both In Vivo and In Vitro<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Breakdown of Tolerance to a Neo-Self Antigen in Double Transgenic Mice in Which B Cells Present the Antigen

Alexander F. de Vos; Atsuki Fukushima; Mark C. Lobanoff; Barbara P. Vistica; James C. Lai; Jean-Charles Grivel; Eric F. Wawrousek; Scott M. Whitcup; Igal Gery

J Immunol (2000) 164 (9): 4594–4600.

Abstract

View articletitled, Breakdown of Tolerance to a Neo-Self Antigen in Double Transgenic Mice in Which B Cells Present the Antigen

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A Physiological Ligand of Positive Selection Is Seen with High Specificity ¹

Stefan Irion; Rance E. Berg; Uwe D. Staerz

J Immunol (2000) 164 (9): 4601–4606.

Abstract

View articletitled, A Physiological Ligand of Positive Selection Is Seen with High Specificity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Stat3-Dependent Induction of p19^INK4D by IL-10 Contributes to Inhibition of Macrophage Proliferation ¹

Anne-Marie O’Farrell; David A. Parry; Frederique Zindy; Martine F. Roussel; Emma Lees; Kevin W. Moore; Alice L.-F. Mui

J Immunol (2000) 164 (9): 4607–4615.

Abstract

View articletitled, Stat3-Dependent Induction of p19INK4D by IL-10 Contributes to Inhibition of Macrophage Proliferation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Linker Phosphorylation Site Tyr²⁹² Mediates the Negative Regulatory Effect of Cbl on ZAP-70 in T Cells ¹

Navin Rao; Mark L. Lupher, Jr.; Satoshi Ota; Kris A. Reedquist; Brian J. Druker; Hamid Band

J Immunol (2000) 164 (9): 4616–4626.

Abstract

View articletitled, The Linker Phosphorylation Site Tyr292 Mediates the Negative Regulatory Effect of Cbl on ZAP-70 in T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional and Phenotypic Evidence for Presentation of Eα_52–68 Structurally Related Self-Peptide(s) in I-Eα-Deficient Mice ¹

Christophe Viret; Charles A. Janeway, Jr.

J Immunol (2000) 164 (9): 4627–4634.

Abstract

View articletitled, Functional and Phenotypic Evidence for Presentation of Eα52–68 Structurally Related Self-Peptide(s) in I-Eα-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Increased DNA Vaccine Delivery and Immunogenicity by Electroporation In Vivo

Georg Widera; Melissa Austin; Dietmar Rabussay; Cheryl Goldbeck; Susan W. Barnett; Minchao Chen; Louisa Leung; Gillis R. Otten; Kent Thudium; Mark J. Selby; Jeffrey B. Ulmer

J Immunol (2000) 164 (9): 4635–4640.

Abstract

View articletitled, Increased DNA Vaccine Delivery and Immunogenicity by Electroporation In Vivo

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Cell Death-Associated Translocation of Plasma Membrane Components Induced by CTL ¹

Yukishige Kawasaki; Takako Saito; Yoshiko Shirota-Someya; Yuko Ikegami; Hajime Komano; Mi-Heon Lee; Christopher J. Froelich; Nobukata Shinohara; Hajime Takayama

J Immunol (2000) 164 (9): 4641–4648.

Abstract

View articletitled, Cell Death-Associated Translocation of Plasma Membrane Components Induced by CTL<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Thymic Dendritic Cells Express Inducible Nitric Oxide Synthase and Generate Nitric Oxide in Response to Self- and Alloantigens ¹

Sistiana Aiello; Marina Noris; Giampiero Piccinini; Susanna Tomasoni; Federica Casiraghi; Samantha Bonazzola; Marilena Mister; Mohamed H. Sayegh; Giuseppe Remuzzi

J Immunol (2000) 164 (9): 4649–4658.

Abstract

View articletitled, Thymic Dendritic Cells Express Inducible Nitric Oxide Synthase and Generate Nitric Oxide in Response to Self- and Alloantigens<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Stat4 Is Expressed in Activated Peripheral Blood Monocytes, Dendritic Cells, and Macrophages at Sites of Th1-Mediated Inflammation ¹

David M. Frucht; Martin Aringer; Jérôme Galon; Carol Danning; Martin Brown; Samuel Fan; Michael Centola; Chang-You Wu; Nubuo Yamada; Hani El Gabalawy; John J. O’Shea

J Immunol (2000) 164 (9): 4659–4664.

Abstract

View articletitled, Stat4 Is Expressed in Activated Peripheral Blood Monocytes, Dendritic Cells, and Macrophages at Sites of Th1-Mediated Inflammation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cytoprotection of Human Umbilical Vein Endothelial Cells Against Apoptosis and CTL-Mediated Lysis Provided by Caspase-Resistant Bcl-2 Without Alterations in Growth or Activation Responses ¹

Lian Zheng; Thomas J. Dengler; Martin S. Kluger; Lisa A. Madge; Jeffrey S. Schechner; Stephen E. Maher; Jordan S. Pober; Alfred L. M. Bothwell

J Immunol (2000) 164 (9): 4665–4671.

Abstract

View articletitled, Cytoprotection of Human Umbilical Vein Endothelial Cells Against Apoptosis and CTL-Mediated Lysis Provided by Caspase-Resistant Bcl-2 Without Alterations in Growth or Activation Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6 ¹

Jürgen Müllberg; Till Geib; Thomas Jostock; Susanne H. Hoischen; Petra Vollmer; Nicole Voltz; David Heinz; Peter R. Galle; Mariam Klouche; Stefan Rose-John

J Immunol (2000) 164 (9): 4672–4677.

Abstract

View articletitled, IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells ¹

Faiyaz Ahmad; Li-Na Cong; Lena Stenson Holst; Ling-Mei Wang; Tova Rahn Landstrom; Jaclyn H. Pierce; Michael J. Quon; Eva Degerman; Vincent C. Manganiello

J Immunol (2000) 164 (9): 4678–4688.

Abstract

View articletitled, Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of Human Inducible Costimulator Ligand Expression and Function ¹

Alexandra Aicher; Martha Hayden-Ledbetter; William A. Brady; Antonio Pezzutto; Guenther Richter; Dario Magaletti; Sonya Buckwalter; Jeffrey A. Ledbetter; Edward A. Clark

J Immunol (2000) 164 (9): 4689–4696.

Abstract

View articletitled, Characterization of Human Inducible Costimulator Ligand Expression and Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MHC Class II-Bound Self Peptides from Autoimmune MRL/lpr Mice Reveal Potential T Cell Epitopes for Autoantibody Production in Murine Systemic Lupus Erythematosus ¹

John H. Freed; Amy Marrs; Jennifer VanderWall; Philip L. Cohen; Robert A. Eisenberg

J Immunol (2000) 164 (9): 4697–4705.

Abstract

View articletitled, MHC Class II-Bound Self Peptides from Autoimmune MRL/lpr Mice Reveal Potential T Cell Epitopes for Autoantibody Production in Murine Systemic Lupus Erythematosus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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DO11.10 and OT-II T Cells Recognize a C-Terminal Ovalbumin 323–339 Epitope ¹

Jennifer M. Robertson; Peter E. Jensen; Brian D. Evavold

J Immunol (2000) 164 (9): 4706–4712.

Abstract

View articletitled, DO11.10 and OT-II T Cells Recognize a C-Terminal Ovalbumin 323–339 Epitope<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Accelerated Proteasomal Degradation of Membrane Ig Heavy Chains ¹

Siew C. Ho; Subhra Chaudhuri; Anand Bachhawat; Kenneth McDonald; Shiv Pillai

J Immunol (2000) 164 (9): 4713–4719.

Abstract

View articletitled, Accelerated Proteasomal Degradation of Membrane Ig Heavy Chains<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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RGS Molecule Expression in Murine B Lymphocytes and Ability to Down-Regulate Chemotaxis to Lymphoid Chemokines ¹ ^²

Karin Reif; Jason G. Cyster

J Immunol (2000) 164 (9): 4720–4729.

Abstract

View articletitled, RGS Molecule Expression in Murine B Lymphocytes and Ability to Down-Regulate Chemotaxis to Lymphoid Chemokines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Characterization of Superantigen-Induced Clonal Deletion with a Novel Clan III-Restricted Avian Monoclonal Antibody: Exploiting Evolutionary Distance to Create Antibodies Specific for a Conserved V_H Region Surface ¹

Stephen P. Cary; James Lee; Raymond Wagenknecht; Gregg J. Silverman

J Immunol (2000) 164 (9): 4730–4741.

Abstract

View articletitled, Characterization of Superantigen-Induced Clonal Deletion with a Novel Clan III-Restricted Avian Monoclonal Antibody: Exploiting Evolutionary Distance to Create Antibodies Specific for a Conserved VH Region Surface<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Molecular Mechanisms of Target Recognition in an Innate Immune System: Interactions Among Factor H, C3b, and Target in the Alternative Pathway of Human Complement ¹ ^²

Michael K. Pangburn; Kerry L. W. Pangburn; Vesa Koistinen; Seppo Meri; Ajay K. Sharma

J Immunol (2000) 164 (9): 4742–4751.

Abstract

View articletitled, Molecular Mechanisms of Target Recognition in an Innate Immune System: Interactions Among Factor H, C3b, and Target in the Alternative Pathway of Human Complement<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Biosynthesis and Posttranslational Regulation of Human IL-12 ¹

Giuseppe Carra; Franca Gerosa; Giorgio Trinchieri

J Immunol (2000) 164 (9): 4752–4761.

Abstract

View articletitled, Biosynthesis and Posttranslational Regulation of Human IL-12<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Switch in Distinct IκBα Degradation Mechanisms Mediates Constitutive NF-κB Activation in Mature B Cells ¹

Erika R. Fields; Bradley J. Seufzer; Eugene M. Oltz; Shigeki Miyamoto

J Immunol (2000) 164 (9): 4762–4767.

Abstract

View articletitled, A Switch in Distinct IκBα Degradation Mechanisms Mediates Constitutive NF-κB Activation in Mature B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Neutralization of Maternal IL-4 Modulates Congenital Protozoal Transmission: Comparison of Innate Versus Acquired Immune Responses ¹

Maureen T. Long; Timothy V. Baszler

J Immunol (2000) 164 (9): 4768–4774.

Abstract

View articletitled, Neutralization of Maternal IL-4 Modulates Congenital Protozoal Transmission: Comparison of Innate Versus Acquired Immune Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Cytomegalovirus Strain-Dependent Changes in NK Cell Recognition of Infected Fibroblasts ¹

Cristina Cerboni; Mehrdad Mousavi-Jazi; Annika Linde; Kalle Söderström; Maria Brytting; Britta Wahren; Klas Kärre; Ennio Carbone

J Immunol (2000) 164 (9): 4775–4782.

Abstract

View articletitled, Human Cytomegalovirus Strain-Dependent Changes in NK Cell Recognition of Infected Fibroblasts<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Requirement of Endogenous Stem Cell Factor and Granulocyte-Colony-Stimulating Factor for IL-17-Mediated Granulopoiesis ¹

Paul Schwarzenberger; Weitao Huang; Peng Ye; Peter Oliver; Misty Manuel; Zili Zhang; Gregory Bagby; Steve Nelson; Jay K. Kolls

J Immunol (2000) 164 (9): 4783–4789.

Abstract

View articletitled, Requirement of Endogenous Stem Cell Factor and Granulocyte-Colony-Stimulating Factor for IL-17-Mediated Granulopoiesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evidence for Human CD4⁺ T Cells in the CD1-Restricted Repertoire: Derivation of Mycobacteria-Reactive T Cells from Leprosy Lesions ¹

Peter A. Sieling; Maria-Teresa Ochoa; Denis Jullien; David S. Leslie; Shereen Sabet; Jean-Pierre Rosat; Anne E. Burdick; Thomas H. Rea; Michael B. Brenner; Steven A. Porcelli; Robert L. Modlin

J Immunol (2000) 164 (9): 4790–4796.

Abstract

View articletitled, Evidence for Human CD4+ T Cells in the CD1-Restricted Repertoire: Derivation of Mycobacteria-Reactive T Cells from Leprosy Lesions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Linkage of Foreign Carrier Protein to a Self-Tumor Antigen Enhances the Immunogenicity of a Pulsed Dendritic Cell Vaccine ¹

John M. Timmerman; Ronald Levy

J Immunol (2000) 164 (9): 4797–4803.

Abstract

View articletitled, Linkage of Foreign Carrier Protein to a Self-Tumor Antigen Enhances the Immunogenicity of a Pulsed Dendritic Cell Vaccine<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Synthetic Endotoxin-Binding Peptides Block Endotoxin- Triggered TNF-α Production by Macrophages In Vitro and In Vivo and Prevent Endotoxin-Mediated Toxic Shock

Silke Dankesreiter; Adolf Hoess; Jens Schneider-Mergener; Hermann Wagner; Thomas Miethke

J Immunol (2000) 164 (9): 4804–4811.

Abstract

View articletitled, Synthetic Endotoxin-Binding Peptides Block Endotoxin- Triggered TNF-α Production by Macrophages In Vitro and In Vivo and Prevent Endotoxin-Mediated Toxic Shock

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Regulation and Role of IFN-γ in the Innate Resistance to Infection with Chlamydia pneumoniae¹

Martín E. Rottenberg; Antonio Gigliotti Rothfuchs; Dulceaydee Gigliotti; Monica Ceausu; Clas Une; Victor Levitsky; Hans Wigzell

J Immunol (2000) 164 (9): 4812–4818.

Abstract

View articletitled, Regulation and Role of IFN-γ in the Innate Resistance to Infection with Chlamydia pneumoniae<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In BALB/c Mice, IL-4 Production During the Initial Phase of Infection with Leishmania major Is Necessary and Sufficient to Instruct Th2 Cell Development Resulting in Progressive Disease ¹

Hayo Himmelrich; Pascal Launois; Ivan Maillard; Tilo Biedermann; Fabienne Tacchini-Cottier; Richard M. Locksley; Martin Röcken; Jacques A. Louis

J Immunol (2000) 164 (9): 4819–4825.

Abstract

View articletitled, In BALB/c Mice, IL-4 Production During the Initial Phase of Infection with Leishmania major Is Necessary and Sufficient to Instruct Th2 Cell Development Resulting in Progressive Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phenotype and Functions of Brain Dendritic Cells Emerging During Chronic Infection of Mice with Toxoplasma gondii¹

Hans-Georg Fischer; Ursula Bonifas; Gaby Reichmann

J Immunol (2000) 164 (9): 4826–4834.

Abstract

View articletitled, Phenotype and Functions of Brain Dendritic Cells Emerging During Chronic Infection of Mice with Toxoplasma gondii<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Biological Correlates of Capsular (Quellung) Reactions of Cryptococcus neoformans¹

Tracy C. MacGill; Randall S. MacGill; Arturo Casadevall; Thomas R. Kozel

J Immunol (2000) 164 (9): 4835–4842.

Abstract

View articletitled, Biological Correlates of Capsular (Quellung) Reactions of Cryptococcus neoformans<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Intersection of Group I CD1 Molecules and Mycobacteria in Different Intracellular Compartments of Dendritic Cells ¹

Ulrich E. Schaible; Kristine Hagens; Karsten Fischer; Helen L. Collins; Stefan H. E. Kaufmann

J Immunol (2000) 164 (9): 4843–4852.

Abstract

View articletitled, Intersection of Group I CD1 Molecules and Mycobacteria in Different Intracellular Compartments of Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Up-Regulation of VCAM-1 and Differential Expansion of β Integrin-Expressing T Lymphocytes Are Associated with Immunity to Pulmonary Mycobacterium tuberculosis Infection ¹

Carl G. Feng; Warwick J. Britton; Umaimainthan Palendira; Natalie L. Groat; Helen Briscoe; Andrew G. D. Bean

J Immunol (2000) 164 (9): 4853–4860.

Abstract

View articletitled, Up-Regulation of VCAM-1 and Differential Expansion of β Integrin-Expressing T Lymphocytes Are Associated with Immunity to Pulmonary Mycobacterium tuberculosis Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Apoptotic Thymocyte Clearance in Scavenger Receptor Class A-Deficient Mice Is Apparently Normal

Nick Platt; Hiroshi Suzuki; Tatsuhiko Kodama; Siamon Gordon

J Immunol (2000) 164 (9): 4861–4867.

Abstract

View articletitled, Apoptotic Thymocyte Clearance in Scavenger Receptor Class A-Deficient Mice Is Apparently Normal

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Le^y/H: An Endothelial-Selective, Cytokine-Inducible, Angiogenic Mediator ¹

Margaret M. Halloran; William W. Carley; Peter J. Polverini; Catherine J. Haskell; Stacie Phan; Byron J. Anderson; James M. Woods; Phillip L. Campbell; Michael V. Volin; Annika E. Bäcker; Alisa E. Koch

J Immunol (2000) 164 (9): 4868–4877.

Abstract

View articletitled, Ley/H: An Endothelial-Selective, Cytokine-Inducible, Angiogenic Mediator<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-6 Is Required for the Development of Th1 Cell-Mediated Murine Colitis ¹

Mitsunari Yamamoto; Kazuyuki Yoshizaki; Tadamitsu Kishimoto; Hiroaki Ito

J Immunol (2000) 164 (9): 4878–4882.

Abstract

View articletitled, IL-6 Is Required for the Development of Th1 Cell-Mediated Murine Colitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Long-Term Survival of Hamster Hearts in Presensitized Rats ¹

Yuan Lin; Miguel P. Soares; Koichiro Sato; Eva Csizmadia; Simon C. Robson; Neal Smith; Fritz H. Bach

J Immunol (2000) 164 (9): 4883–4892.

Abstract

View articletitled, Long-Term Survival of Hamster Hearts in Presensitized Rats<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Kinetics and Mechanism of ATP-Dependent IL-1β Release from Microglial Cells ¹

Juana M. Sanz; Francesco Di Virgilio

J Immunol (2000) 164 (9): 4893–4898.

Abstract

View articletitled, Kinetics and Mechanism of ATP-Dependent IL-1β Release from Microglial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Genetic Factors Determine the Contribution of Leukotrienes to Acute Inflammatory Responses ¹

Jennifer L. Goulet; Robert S. Byrum; Mikelle L. Key; MyTrang Nguyen; Victoria A. Wagoner; Beverly H. Koller

J Immunol (2000) 164 (9): 4899–4907.

Abstract

View articletitled, Genetic Factors Determine the Contribution of Leukotrienes to Acute Inflammatory Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Secretory Phospholipases A₂ Induce β-Glucuronidase Release and IL-6 Production from Human Lung Macrophages ¹

Massimo Triggiani; Francescopaolo Granata; Alfonso Oriente; Valeria De Marino; Marco Gentile; Cecilia Calabrese; Cristiana Palumbo; Gianni Marone

J Immunol (2000) 164 (9): 4908–4915.

Abstract

View articletitled, Secretory Phospholipases A2 Induce β-Glucuronidase Release and IL-6 Production from Human Lung Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ and TNF Regulate Macrophage Expression of the Chemotactic S100 Protein S100A8 ¹

Ken Xu; Carolyn L. Geczy

J Immunol (2000) 164 (9): 4916–4923.

Abstract

View articletitled, IFN-γ and TNF Regulate Macrophage Expression of the Chemotactic S100 Protein S100A8<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

The T Cell Repertoire Selected In Vitro Against EBV: Diversity, Specificity, and Improved Purification Through Early IL-2 Receptor α-Chain (CD25)-Positive Selection ¹

Catherine Ibisch; Xavier Saulquin; Géraldine Gallot; Régine Vivien; Christophe Ferrand; Pierre Tiberghien; Elisabeth Houssaint; Henri Vié

J Immunol (2000) 164 (9): 4924–4932.

Abstract

View articletitled, The T Cell Repertoire Selected In Vitro Against EBV: Diversity, Specificity, and Improved Purification Through Early IL-2 Receptor α-Chain (CD25)-Positive Selection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Baseline Airway Hyperreactivity in A/J Mice Is not Mediated by Cells of the Adaptive Immune System ¹

Husein Hadeiba; David B. Corry; Richard M. Locksley

J Immunol (2000) 164 (9): 4933–4940.

Abstract

View articletitled, Baseline Airway Hyperreactivity in A/J Mice Is not Mediated by Cells of the Adaptive Immune System<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Role of Fas/Fas Ligand Interactions in Cytolysis of Primary and Metastatic Colon Carcinoma Cell Lines by Human Antigen-Specific CD8⁺ CTL

Elke S. Bergmann-Leitner; Scott I. Abrams

J Immunol (2000) 164 (9): 4941–4954.

Abstract

View articletitled, Differential Role of Fas/Fas Ligand Interactions in Cytolysis of Primary and Metastatic Colon Carcinoma Cell Lines by Human Antigen-Specific CD8+ CTL

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Macrophage Colony-Stimulating Factor Antagonists Inhibit Replication of HIV-1 in Human Macrophages

Joseph Kutza; Lynne Crim; Steven Feldman; Mark P. Hayes; Marion Gruber; Judy Beeler; Kathleen A. Clouse

J Immunol (2000) 164 (9): 4955–4960.

Abstract

View articletitled, Macrophage Colony-Stimulating Factor Antagonists Inhibit Replication of HIV-1 in Human Macrophages

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T Cell Activity After Dendritic Cell Vaccination Is Dependent on Both the Type of Antigen and the Mode of Delivery ¹

Jonathan S. Serody; Edward J. Collins; Roland M. Tisch; Jennifer J. Kuhns; Jeffrey A. Frelinger

J Immunol (2000) 164 (9): 4961–4967.

Abstract

View articletitled, T Cell Activity After Dendritic Cell Vaccination Is Dependent on Both the Type of Antigen and the Mode of Delivery<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of AIDS Virus-Specific CTL Activity in Fresh, Unstimulated Peripheral Blood Lymphocytes from Rhesus Macaques Vaccinated with a DNA Prime/Modified Vaccinia Virus Ankara Boost Regimen ¹

Todd M. Allen; Thorsten U. Vogel; Deborah H. Fuller; Bianca R. Mothé; Susan Steffen; Jon E. Boyson; Tim Shipley; Jim Fuller; Tomas Hanke; Alessandro Sette; John D. Altman; Bernard Moss; Andrew J. McMichael; David I. Watkins

J Immunol (2000) 164 (9): 4968–4978.

Abstract

View articletitled, Induction of AIDS Virus-Specific CTL Activity in Fresh, Unstimulated Peripheral Blood Lymphocytes from Rhesus Macaques Vaccinated with a DNA Prime/Modified Vaccinia Virus Ankara Boost Regimen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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