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CUTTING EDGE

Cutting Edge: In Situ Tetramer Staining of Antigen-Specific T Cells in Tissues ¹

Pamela J. Skinner; Mark A. Daniels; Clint S. Schmidt; Stephen C. Jameson; Ashley T. Haase

J Immunol (2000) 165 (2): 613–617.

Abstract

View articletitled, Cutting Edge: In Situ Tetramer Staining of Antigen-Specific T Cells in Tissues<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2 ¹

Matthew Hirschfeld; Ying Ma; John H. Weis; Stefanie N. Vogel; Janis J. Weis

J Immunol (2000) 165 (2): 618–622.

Abstract

View articletitled, Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: DNA Immunization with Minigenes of Carbohydrate Mimotopes Induce Functional Anti-Carbohydrate Antibody Response ¹

Thomas Kieber-Emmons; Behjatolah Monzavi-Karbassi; Bin Wang; Ping Luo; David B. Weiner

J Immunol (2000) 165 (2): 623–627.

Abstract

View articletitled, Cutting Edge: DNA Immunization with Minigenes of Carbohydrate Mimotopes Induce Functional Anti-Carbohydrate Antibody Response<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: IL-12 Is Required for the Maintenance of IFN-γ Production in T Cells Mediating Chronic Resistance to the Intracellular Pathogen, Toxoplasma gondii

George Yap; Michael Pesin; Alan Sher

J Immunol (2000) 165 (2): 628–631.

Abstract

View articletitled, Cutting Edge: IL-12 Is Required for the Maintenance of IFN-γ Production in T Cells Mediating Chronic Resistance to the Intracellular Pathogen, Toxoplasma gondii

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Cutting Edge: Chandra, a Novel Four-Transmembrane Domain Protein Differentially Expressed in Helper Type 1 Lymphocytes

Chandrasekar Venkataraman; Gabriele Schaefer; Ulrike Schindler

J Immunol (2000) 165 (2): 632–636.

Abstract

View articletitled, Cutting Edge: Chandra, a Novel Four-Transmembrane Domain Protein Differentially Expressed in Helper Type 1 Lymphocytes

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

The Abrogation of Allosensitization Following the Induction of Mixed Allogeneic Chimerism ¹

Yolonda L. Colson; Matthew J. Schuchert; Suzanne T. Ildstad

J Immunol (2000) 165 (2): 637–644.

Abstract

View articletitled, The Abrogation of Allosensitization Following the Induction of Mixed Allogeneic Chimerism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Langerhans Cells That Have Matured In Vivo in the Absence of T Cells Are Fully Capable of Inducing a Helper CD4 as Well as a Cytotoxic CD8 Response ¹

An De Creus; Katrien Van Beneden; Tom Taghon; Frank Stolz; Veronique Debacker; Jean Plum; Georges Leclercq

J Immunol (2000) 165 (2): 645–653.

Abstract

View articletitled, Langerhans Cells That Have Matured In Vivo in the Absence of T Cells Are Fully Capable of Inducing a Helper CD4 as Well as a Cytotoxic CD8 Response<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of a Minimal T Cell Epitope Recognized by Antinucleosome Th Cells in the C-Terminal Region of Histone H4 ¹

Patrice Decker; Anne Le Moal; Jean-Paul Briand; Sylviane Muller

J Immunol (2000) 165 (2): 654–662.

Abstract

View articletitled, Identification of a Minimal T Cell Epitope Recognized by Antinucleosome Th Cells in the C-Terminal Region of Histone H4<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Direct Immunosuppressive Effects of EBV-Encoded Latent Membrane Protein 1

Danny F. Dukers; Pauline Meij; Marcel B. H. J. Vervoort; Wim Vos; Rik J. Scheper; Chris J. L. M. Meijer; Elisabeth Bloemena; Jaap M. Middeldorp

J Immunol (2000) 165 (2): 663–670.

Abstract

View articletitled, Direct Immunosuppressive Effects of EBV-Encoded Latent Membrane Protein 1

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Membrane Lymphotoxin Is Required for the Development of Different Subpopulations of NK T Cells ¹ ^²

Dirk Elewaut; Laurent Brossay; Sybil M. Santee; Olga V. Naidenko; Nicolas Burdin; Hilde De Winter; Jennifer Matsuda; Carl F. Ware; Hilde Cheroutre; Mitchell Kronenberg

J Immunol (2000) 165 (2): 671–679.

Abstract

View articletitled, Membrane Lymphotoxin Is Required for the Development of Different Subpopulations of NK T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Stimulation of the B Cell Receptor, CD86 (B7-2), and the β₂-Adrenergic Receptor Intrinsically Modulates the Level of IgG1 and IgE Produced per B Cell ¹

Deborah J. Kasprowicz; Adam P. Kohm; Michael T. Berton; Andrezj J. Chruscinski; Arlene Sharpe; Virginia M. Sanders

J Immunol (2000) 165 (2): 680–690.

Abstract

View articletitled, Stimulation of the B Cell Receptor, CD86 (B7-2), and the β2-Adrenergic Receptor Intrinsically Modulates the Level of IgG1 and IgE Produced per B Cell<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activated Self-MHC-Reactive T Cells Have the Cytokine Phenotype of Th3/T Regulatory Cell 1 T Cells

Atsushi Kitani; Kevin Chua; Kazuhiko Nakamura; Warren Strober

J Immunol (2000) 165 (2): 691–702.

Abstract

View articletitled, Activated Self-MHC-Reactive T Cells Have the Cytokine Phenotype of Th3/T Regulatory Cell 1 T Cells

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Secondary V(D)J Rearrangements and B Cell Receptor-Mediated Down-Regulation of Recombination Activating Gene-2 Expression in a Murine B Cell Line ¹

Jérôme Maës; Yael Caspi; François Rougeon; Joseph Haimovich; Michele Goodhardt

J Immunol (2000) 165 (2): 703–709.

Abstract

View articletitled, Secondary V(D)J Rearrangements and B Cell Receptor-Mediated Down-Regulation of Recombination Activating Gene-2 Expression in a Murine B Cell Line<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Uveal Melanoma Cells Produce Macrophage Migration-Inhibitory Factor to Prevent Lysis by NK Cells ¹

Amanda C. Repp; Elizabeth S. Mayhew; Sherine Apte; Jerry Y. Niederkorn

J Immunol (2000) 165 (2): 710–715.

Abstract

View articletitled, Human Uveal Melanoma Cells Produce Macrophage Migration-Inhibitory Factor to Prevent Lysis by NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4⁺ CCR7⁺ Human Memory T Cells ¹

Patrick Jourdan; Jean-Pierre Vendrell; Marie-France Huguet; Michel Segondy; Jean Bousquet; Jérôme Pène; Hans Yssel

J Immunol (2000) 165 (2): 716–724.

Abstract

View articletitled, Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4+ CCR7+ Human Memory T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activation of Antigen-Specific CD4⁺ Th2 Cells and B Cells In Vivo Increases Norepinephrine Release in the Spleen and Bone Marrow ¹

Adam P. Kohm; Yueming Tang; Virginia M. Sanders; Stephen B. Jones

J Immunol (2000) 165 (2): 725–733.

Abstract

View articletitled, Activation of Antigen-Specific CD4+ Th2 Cells and B Cells In Vivo Increases Norepinephrine Release in the Spleen and Bone Marrow<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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An Epithelial Cell Line That Can Stimulate Alloproliferation of Resting CD4⁺ T Cells, But Not After IFN-γ Stimulation ¹

Charlotte Lawson; Ann M. McCormack; David Moyes; Sheng Yun; John W. Fabre; Magdi Yacoub; Marlene L. Rose

J Immunol (2000) 165 (2): 734–742.

Abstract

View articletitled, An Epithelial Cell Line That Can Stimulate Alloproliferation of Resting CD4+ T Cells, But Not After IFN-γ Stimulation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TNF-α and IFN-γ Regulate Expression and Function of the Fas System in the Seminiferous Epithelium

Anna Riccioli; Donatella Starace; Alessio D’Alessio; Giuseppe Starace; Fabrizio Padula; Paola De Cesaris; Antonio Filippini; Elio Ziparo

J Immunol (2000) 165 (2): 743–749.

Abstract

View articletitled, TNF-α and IFN-γ Regulate Expression and Function of the Fas System in the Seminiferous Epithelium

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Involvement of an ATP-Dependent Peptide Chaperone in Cross-Presentation After DNA Immunization ¹

Udayasankar Kumaraguru; Richard J. D. Rouse; Smita K. Nair; Barry D. Bruce; Barry T. Rouse

J Immunol (2000) 165 (2): 750–759.

Abstract

View articletitled, Involvement of an ATP-Dependent Peptide Chaperone in Cross-Presentation After DNA Immunization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Facing Two T Cell Epitopes: A Degree of Randomness in the Primary Response Is Lost Upon Secondary Immunization ¹

Philippe Bousso; Fabrice Lemaı̂tre; Janine Bilsborough; Philippe Kourilsky

J Immunol (2000) 165 (2): 760–767.

Abstract

View articletitled, Facing Two T Cell Epitopes: A Degree of Randomness in the Primary Response Is Lost Upon Secondary Immunization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Overexpression of the Proteasome Subunits LMP2, LMP7, and MECL-1, But Not PA28α/β, Enhances the Presentation of an Immunodominant Lymphocytic Choriomeningitis Virus T Cell Epitope ¹

Katrin Schwarz; Maries van den Broek; Susanne Kostka; Regine Kraft; Andrea Soza; Gunter Schmidtke; Peter-M. Kloetzel; Marcus Groettrup

J Immunol (2000) 165 (2): 768–778.

Abstract

View articletitled, Overexpression of the Proteasome Subunits LMP2, LMP7, and MECL-1, But Not PA28α/β, Enhances the Presentation of an Immunodominant Lymphocytic Choriomeningitis Virus T Cell Epitope<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Gr-1⁺ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation ¹

Sergei A. Kusmartsev; Yu Li; Shu-Hsia Chen

J Immunol (2000) 165 (2): 779–785.

Abstract

View articletitled, Gr-1+ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Engagement of CD153 (CD30 Ligand) by CD30⁺ T Cells Inhibits Class Switch DNA Recombination and Antibody Production in Human IgD⁺ IgM⁺ B Cells ¹

Andrea Cerutti; Andràs Schaffer; Raymond G. Goodwin; Shefali Shah; Hong Zan; Scott Ely; Paolo Casali

J Immunol (2000) 165 (2): 786–794.

Abstract

View articletitled, Engagement of CD153 (CD30 Ligand) by CD30+ T Cells Inhibits Class Switch DNA Recombination and Antibody Production in Human IgD+ IgM+ B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phenotypic and Functional Characterization of Mouse Hepatic CD8α⁺ Lymphoid-Related Dendritic Cells ¹

Peta J. O’Connell; Adrian E. Morelli; Alison J. Logar; Angus W. Thomson

J Immunol (2000) 165 (2): 795–803.

Abstract

View articletitled, Phenotypic and Functional Characterization of Mouse Hepatic CD8α+ Lymphoid-Related Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia (aly) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase ¹

Takuji Yamada; Tasuku Mitani; Kazuko Yorita; Daisuke Uchida; Akemi Matsushima; Kikue Iwamasa; Shigeru Fujita; Mitsuru Matsumoto

J Immunol (2000) 165 (2): 804–812.

Abstract

View articletitled, Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia (aly) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Molecular Basis for Nonanaphylactogenicity of a Monoclonal Anti-IgE Antibody ¹

Michael P. Rudolf; Adrian W. Zuercher; Andreas Nechansky; Christine Ruf; Monique Vogel; Sylvia M. Miescher; Beda M. Stadler; Franz Kricek

J Immunol (2000) 165 (2): 813–819.

Abstract

View articletitled, Molecular Basis for Nonanaphylactogenicity of a Monoclonal Anti-IgE Antibody<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Role for the Region Encompassing the c″ Strand of a TCR Vα Domain in T Cell Activation Events ¹

Ayub Qadri; Caius G. Radu; Jayant Thatte; Petru Cianga; Bertram T. Ober; Raimund J. Ober; E. Sally Ward

J Immunol (2000) 165 (2): 820–829.

Abstract

View articletitled, A Role for the Region Encompassing the c″ Strand of a TCR Vα Domain in T Cell Activation Events<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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B Cell Receptor Engagement and T Cell Contact Induce bcl-6 Somatic Hypermutation in Human B Cells: Identity with Ig Hypermutation ¹

Hong Zan; Zongdong Li; Kozaburo Yamaji; Patricia Dramitinos; Andrea Cerutti; Paolo Casali

J Immunol (2000) 165 (2): 830–839.

Abstract

View articletitled, B Cell Receptor Engagement and T Cell Contact Induce bcl-6 Somatic Hypermutation in Human B Cells: Identity with Ig Hypermutation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD164 Monoclonal Antibodies That Block Hemopoietic Progenitor Cell Adhesion and Proliferation Interact with the First Mucin Domain of the CD164 Receptor ¹

Regis Doyonnas; James Yi-Hsin Chan; Lisa H. Butler; Irene Rappold; Jane E. Lee-Prudhoe; Andrew C. W. Zannettino; Paul J. Simmons; Hans-Jörg Bühring; Jean-Pierre Levesque; Suzanne M. Watt

J Immunol (2000) 165 (2): 840–851.

Abstract

View articletitled, CD164 Monoclonal Antibodies That Block Hemopoietic Progenitor Cell Adhesion and Proliferation Interact with the First Mucin Domain of the CD164 Receptor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Underutilization of the Vκ10C Gene in the B Cell Repertoire Is Due to the Loss of Productive VJ Rearrangements During B Cell Development

Sean P. Fitzsimmons; Kathleen J. Clark; Howard S. Mostowski; Marjorie A. Shapiro

J Immunol (2000) 165 (2): 852–859.

Abstract

View articletitled, Underutilization of the Vκ10C Gene in the B Cell Repertoire Is Due to the Loss of Productive VJ Rearrangements During B Cell Development

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Repression of IL-2 Promoter Activity by the Novel Basic Leucine Zipper p21^SNFT Protein ¹ ^²

Milena Iacobelli; William Wachsman; Kathleen L. McGuire

J Immunol (2000) 165 (2): 860–868.

Abstract

View articletitled, Repression of IL-2 Promoter Activity by the Novel Basic Leucine Zipper p21SNFT Protein<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Identification of a Novel Tumor-Specific CTL Epitope Presented by RMA, EL-4, and MBL-2 Lymphomas Reveals Their Common Origin

Thorbald van Hall; Jeroen van Bergen; Peter A. van Veelen; Margriet Kraakman; Lukas C. Heukamp; Frits Koning; Cornelis J. M. Melief; Ferry Ossendorp; Rienk Offringa

J Immunol (2000) 165 (2): 869–877.

Abstract

View articletitled, Identification of a Novel Tumor-Specific CTL Epitope Presented by RMA, EL-4, and MBL-2 Lymphomas Reveals Their Common Origin

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Interaction of C1q and Mannan-Binding Lectin (MBL) with C1r, C1s, MBL-Associated Serine Proteases 1 and 2, and the MBL-Associated Protein MAp19 ¹

Steffen Thiel; Steen V. Petersen; Thomas Vorup-Jensen; Misao Matsushita; Teizo Fujita; Cordula M. Stover; Wilhelm J. Schwaeble; Jens C. Jensenius

J Immunol (2000) 165 (2): 878–887.

Abstract

View articletitled, Interaction of C1q and Mannan-Binding Lectin (MBL) with C1r, C1s, MBL-Associated Serine Proteases 1 and 2, and the MBL-Associated Protein MAp19<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Treatment of Human B Cell Lymphoma Xenografts with a CD3 × CD19 Diabody and T Cells ¹

Björn Cochlovius; Sergey M. Kipriyanov; Marike J. J. G. Stassar; Oliver Christ; Jochen Schuhmacher; Gudrun Strauß; Gerhard Moldenhauer; Melvyn Little

J Immunol (2000) 165 (2): 888–895.

Abstract

View articletitled, Treatment of Human B Cell Lymphoma Xenografts with a CD3 × CD19 Diabody and T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-12 Is Required to Maintain a Th1 Response During Leishmania major Infection ¹

Audrey Y. Park; Brian D. Hondowicz; Phillip Scott

J Immunol (2000) 165 (2): 896–902.

Abstract

View articletitled, IL-12 Is Required to Maintain a Th1 Response During Leishmania major Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Invasive Shigella flexneri Activates NF-κB Through a Lipopolysaccharide-Dependent Innate Intracellular Response and Leads to IL-8 Expression in Epithelial Cells ¹

Dana J. Philpott; Shoji Yamaoka; Alain Israël; Philippe J. Sansonetti

J Immunol (2000) 165 (2): 903–914.

Abstract

View articletitled, Invasive Shigella flexneri Activates NF-κB Through a Lipopolysaccharide-Dependent Innate Intracellular Response and Leads to IL-8 Expression in Epithelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Requirements for the Maintenance of Th1 Immunity In Vivo Following DNA Vaccination: A Potential Immunoregulatory Role for CD8⁺ T Cells

Sanjay Gurunathan; Laura Stobie; Calmin Prussin; David L. Sacks; Nicolas Glaichenhaus; Deborah J. Fowell; Richard M. Locksley; John T. Chang; Chang-You Wu; Robert A. Seder

J Immunol (2000) 165 (2): 915–924.

Abstract

View articletitled, Requirements for the Maintenance of Th1 Immunity In Vivo Following DNA Vaccination: A Potential Immunoregulatory Role for CD8+ T Cells

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Mycobacterium tuberculosis-Reactive CD8⁺ T Lymphocytes: The Relative Contribution of Classical Versus Nonclassical HLA Restriction ¹

David M. Lewinsohn; Andria L. Briden; Steven G. Reed; Kenneth H. Grabstein; Mark R. Alderson

J Immunol (2000) 165 (2): 925–930.

Abstract

View articletitled, Mycobacterium tuberculosis-Reactive CD8+ T Lymphocytes: The Relative Contribution of Classical Versus Nonclassical HLA Restriction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Toll-Like Receptor 2 on γδ T Cells Bearing Invariant Vγ6/Vδ1 Induced by Escherichia coli Infection in Mice ¹

Yasuji Mokuno; Tetsuya Matsuguchi; Manabu Takano; Hitoshi Nishimura; Junji Washizu; Tomohiko Ogawa; Osamu Takeuchi; Shizuo Akira; Yuji Nimura; Yasunobu Yoshikai

J Immunol (2000) 165 (2): 931–940.

Abstract

View articletitled, Expression of Toll-Like Receptor 2 on γδ T Cells Bearing Invariant Vγ6/Vδ1 Induced by Escherichia coli Infection in Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-18 Contributes to Host Resistance Against Infection with Cryptococcus neoformans in Mice with Defective IL-12 Synthesis Through Induction of IFN-γ Production by NK Cells ¹

Kazuyoshi Kawakami; Yoshinobu Koguchi; Mahboob Hossain Qureshi; Akiko Miyazato; Satomi Yara; Yuki Kinjo; Yoichiro Iwakura; Kiyoshi Takeda; Shizuo Akira; Masashi Kurimoto; Atsushi Saito

J Immunol (2000) 165 (2): 941–947.

Abstract

View articletitled, IL-18 Contributes to Host Resistance Against Infection with Cryptococcus neoformans in Mice with Defective IL-12 Synthesis Through Induction of IFN-γ Production by NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of NY-ESO-1 Peptide Analogues Capable of Improved Stimulation of Tumor-Reactive CTL ¹

Ji-Li Chen; P. Rod Dunbar; Uzi Gileadi; Elke Jäger; Sacha Gnjatic; Yasuhiro Nagata; Elisabeth Stockert; Dennis L. Panicali; Yao-Tseng Chen; Alexander Knuth; Lloyd J. Old; Vincenzo Cerundolo

J Immunol (2000) 165 (2): 948–955.

Abstract

View articletitled, Identification of NY-ESO-1 Peptide Analogues Capable of Improved Stimulation of Tumor-Reactive CTL<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Indispensable Role for TNF-α and IFN-γ at the Effector Phase of Liver Injury Mediated by Th1 Cells Specific to Hepatitis B Virus Surface Antigen ¹

Akio Ohta; Masashi Sekimoto; Marimo Sato; Toshiaki Koda; Shin-ichiro Nishimura; Yoichiro Iwakura; Kenji Sekikawa; Takashi Nishimura

J Immunol (2000) 165 (2): 956–961.

Abstract

View articletitled, Indispensable Role for TNF-α and IFN-γ at the Effector Phase of Liver Injury Mediated by Th1 Cells Specific to Hepatitis B Virus Surface Antigen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Macrophage Inflammatory Protein-1α Is a Critical Mediator of Host Defense Against Invasive Pulmonary Aspergillosis in Neutropenic Hosts

Borna Mehrad; Thomas A. Moore; Theodore J. Standiford

J Immunol (2000) 165 (2): 962–968.

Abstract

View articletitled, Macrophage Inflammatory Protein-1α Is a Critical Mediator of Host Defense Against Invasive Pulmonary Aspergillosis in Neutropenic Hosts

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A Natural Model of Leishmania major Infection Reveals a Prolonged “Silent” Phase of Parasite Amplification in the Skin Before the Onset of Lesion Formation and Immunity

Yasmine Belkaid; Susana Mendez; Rosalia Lira; Navin Kadambi; Genevieve Milon; David Sacks

J Immunol (2000) 165 (2): 969–977.

Abstract

View articletitled, A Natural Model of Leishmania major Infection Reveals a Prolonged “Silent” Phase of Parasite Amplification in the Skin Before the Onset of Lesion Formation and Immunity

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IL-10 Converts Human Dendritic Cells into Macrophage-Like Cells with Increased Antibacterial Activity Against Virulent Mycobacterium tuberculosis¹

Daniela Förtsch; Martin Röllinghoff; Steffen Stenger

J Immunol (2000) 165 (2): 978–987.

Abstract

View articletitled, IL-10 Converts Human Dendritic Cells into Macrophage-Like Cells with Increased Antibacterial Activity Against Virulent Mycobacterium tuberculosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Central Role of Double-Stranded RNA-Activated Protein Kinase in Microbial Induction of Nitric Oxide Synthase ¹

Kohsaku Uetani; Sandy D. Der; Maryam Zamanian-Daryoush; Carol de la Motte; Belinda Y. Lieberman; Bryan R. G. Williams; Serpil C. Erzurum

J Immunol (2000) 165 (2): 988–996.

Abstract

View articletitled, Central Role of Double-Stranded RNA-Activated Protein Kinase in Microbial Induction of Nitric Oxide Synthase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Skin-Specific Caspase-1-Transgenic Mice Show Cutaneous Apoptosis and Pre-Endotoxin Shock Condition with a High Serum Level of IL-18 ¹

Kei-ichi Yamanaka; Minoru Tanaka; Hiroko Tsutsui; Thomas S. Kupper; Kunihiko Asahi; Haruki Okamura; Kenji Nakanishi; Misao Suzuki; Nobuhiko Kayagaki; Roy A. Black; Douglas K. Miller; Kunio Nakashima; Masayuki Shimizu; Hitoshi Mizutani

J Immunol (2000) 165 (2): 997–1003.

Abstract

View articletitled, Skin-Specific Caspase-1-Transgenic Mice Show Cutaneous Apoptosis and Pre-Endotoxin Shock Condition with a High Serum Level of IL-18<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A d-Amino Acid Peptide Inhibitor of NF-κB Nuclear Localization Is Efficacious in Models of Inflammatory Disease

Sheri M. Fujihara; Jeffrey S. Cleaveland; Laura S. Grosmaire; Karen K. Berry; Karen A. Kennedy; James J. Blake; James Loy; Bruce M. Rankin; Jeffrey A. Ledbetter; Steven G. Nadler

J Immunol (2000) 165 (2): 1004–1012.

Abstract

View articletitled, A d-Amino Acid Peptide Inhibitor of NF-κB Nuclear Localization Is Efficacious in Models of Inflammatory Disease

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Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin ¹

Navdeep S. Chandel; Wendy C. Trzyna; David S. McClintock; Paul T. Schumacker

J Immunol (2000) 165 (2): 1013–1021.

Abstract

View articletitled, Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice ¹

Lesley E. Smythies; Ken B. Waites; J. Russell Lindsey; Paul R. Harris; Paolo Ghiara; Phillip D. Smith

J Immunol (2000) 165 (2): 1022–1029.

Abstract

View articletitled, Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Complement-Dependent Acute-Phase Expression of C-Reactive Protein and Serum Amyloid P-Component ¹

Alexander J. Szalai; Frederik W. van Ginkel; Yue Wang; Jerry R. McGhee; John E. Volanakis

J Immunol (2000) 165 (2): 1030–1035.

Abstract

View articletitled, Complement-Dependent Acute-Phase Expression of C-Reactive Protein and Serum Amyloid P-Component<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fas and Fas Ligand Mutations Inhibit Autoantibody Production in Pristane-Induced Lupus ¹

Minoru Satoh; Jory P. Weintraub; Hideo Yoshida; Victoria M. Shaheen; Hanno B. Richards; Melody Shaw; Westley H. Reeves

J Immunol (2000) 165 (2): 1036–1043.

Abstract

View articletitled, Fas and Fas Ligand Mutations Inhibit Autoantibody Production in Pristane-Induced Lupus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Distinct Surface-Expressed and Intracellular CXC-Chemokine Receptor 2 Glycoforms in Neutrophils: N-Glycosylation Is Essential for Maintenance of Receptor Surface Expression ¹

Andreas Ludwig; Jan E. Ehlert; Hans-Dieter Flad; Ernst Brandt

J Immunol (2000) 165 (2): 1044–1052.

Abstract

View articletitled, Identification of Distinct Surface-Expressed and Intracellular CXC-Chemokine Receptor 2 Glycoforms in Neutrophils: N-Glycosylation Is Essential for Maintenance of Receptor Surface Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Pro-Carboxypeptidase R is an Acute Phase Protein in the Mouse, Whereas Carboxypeptidase N Is Not ¹ ^²

Tomoo Sato; Takashi Miwa; Hiroyasu Akatsu; Noriyuki Matsukawa; Kyoko Obata; Noriko Okada; William Campbell; Hidechika Okada

J Immunol (2000) 165 (2): 1053–1058.

Abstract

View articletitled, Pro-Carboxypeptidase R is an Acute Phase Protein in the Mouse, Whereas Carboxypeptidase N Is Not<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Isolation, Characterization, and Cloning of Porcine Complement Component C7 ¹

Azin Agah; Michael C. Montalto; Cheri L. Kiesecker; Margaret Morrissey; Meera Grover; Kara L. Whoolery; Russell P. Rother; Gregory L. Stahl

J Immunol (2000) 165 (2): 1059–1065.

Abstract

View articletitled, Isolation, Characterization, and Cloning of Porcine Complement Component C7<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distal Recognition Site for Classical Pathway Convertase Located in the C345C/Netrin Module of Complement Component C5 ¹

Ana Sandoval; Rong Ai; John M. Ostresh; Ronald T. Ogata

J Immunol (2000) 165 (2): 1066–1073.

Abstract

View articletitled, Distal Recognition Site for Classical Pathway Convertase Located in the C345C/Netrin Module of Complement Component C5<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Latent Murine γ-Herpesvirus Infection Is Established in Activated B Cells, Dendritic Cells, and Macrophages ¹

Emilio Flaño; S. Mazher Husain; Jeffery T. Sample; David L. Woodland; Marcia A. Blackman

J Immunol (2000) 165 (2): 1074–1081.

Abstract

View articletitled, Latent Murine γ-Herpesvirus Infection Is Established in Activated B Cells, Dendritic Cells, and Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Maintenance of Large Numbers of Virus-Specific CD8⁺ T Cells in HIV-Infected Progressors and Long-Term Nonprogressors

Juan C. Gea-Banacloche; Stephen A. Migueles; Lisa Martino; W. Lesley Shupert; Andrew C. McNeil; M. Shirin Sabbaghian; Linda Ehler; Calman Prussin; Randy Stevens; Laurie Lambert; John Altman; Claire W. Hallahan; Juan Carlos Lopez Bernaldo de Quiros; Mark Connors

J Immunol (2000) 165 (2): 1082–1092.

Abstract

View articletitled, Maintenance of Large Numbers of Virus-Specific CD8+ T Cells in HIV-Infected Progressors and Long-Term Nonprogressors

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Myelin/Oligodendrocyte Glycoprotein-Induced Autoimmune Encephalomyelitis in Common Marmosets: The Encephalitogenic T Cell Epitope pMOG24–36 Is Presented by a Monomorphic MHC Class II Molecule ¹

Herbert P.M. Brok; Antonio Uccelli; Nicole Kerlero de Rosbo; Ronald E. Bontrop; Luca Roccatagliata; Natasja G. de Groot; Elisabetta Capello; Jon D. Laman; Klaas Nicolay; Gian-Luigi Mancardi; Avraham Ben-Nun; Bert A. ‘t Hart

J Immunol (2000) 165 (2): 1093–1101.

Abstract

View articletitled, Myelin/Oligodendrocyte Glycoprotein-Induced Autoimmune Encephalomyelitis in Common Marmosets: The Encephalitogenic T Cell Epitope pMOG24–36 Is Presented by a Monomorphic MHC Class II Molecule<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Expression of CC Chemokines and the CCR5 Receptor in the Pancreas Is Associated with Progression to Type I Diabetes ¹

Mark J. Cameron; Guillermo A. Arreaza; Marsha Grattan; Craig Meagher; Shayan Sharif; Marie D. Burdick; Robert M. Strieter; Donald N. Cook; Terry L. Delovitch

J Immunol (2000) 165 (2): 1102–1110.

Abstract

View articletitled, Differential Expression of CC Chemokines and the CCR5 Receptor in the Pancreas Is Associated with Progression to Type I Diabetes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD40-CD40 Ligand-Independent Activation of CD8⁺ T Cells Can Trigger Allograft Rejection ¹

Nick D. Jones; Andre Van Maurik; Masaki Hara; Bernd M. Spriewald; Oliver Witzke; Peter J. Morris; Kathryn J. Wood

J Immunol (2000) 165 (2): 1111–1118.

Abstract

View articletitled, CD40-CD40 Ligand-Independent Activation of CD8+ T Cells Can Trigger Allograft Rejection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Determination of Carrier Status for the Wiskott-Aldrich Syndrome by Flow Cytometric Analysis of Wiskott-Aldrich Syndrome Protein Expression in Peripheral Blood Mononuclear Cells ¹

Masafumi Yamada; Tadashi Ariga; Nobuaki Kawamura; Koji Yamaguchi; Makoto Ohtsu; David L. Nelson; Tatsuro Kondoh; Ichiro Kobayashi; Motohiko Okano; Kunihiko Kobayashi; Yukio Sakiyama

J Immunol (2000) 165 (2): 1119–1122.

Abstract

View articletitled, Determination of Carrier Status for the Wiskott-Aldrich Syndrome by Flow Cytometric Analysis of Wiskott-Aldrich Syndrome Protein Expression in Peripheral Blood Mononuclear Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HLA-DR-Promiscuous T Cell Epitopes from Plasmodium falciparum Pre-Erythrocytic-Stage Antigens Restricted by Multiple HLA Class II Alleles ¹ ^²

Denise L. Doolan; Scott Southwood; Robert Chesnut; Ettore Appella; Eduardo Gomez; Allen Richards; Yuichiro I. Higashimoto; Ajesh Maewal; John Sidney; Robert A. Gramzinski; Carl Mason; Davy Koech; Stephen L. Hoffman; Alessandro Sette

J Immunol (2000) 165 (2): 1123–1137.

Abstract

View articletitled, HLA-DR-Promiscuous T Cell Epitopes from Plasmodium falciparum Pre-Erythrocytic-Stage Antigens Restricted by Multiple HLA Class II Alleles<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Killer Cell Activating Receptors Function as Costimulatory Molecules on CD4⁺CD28^null T Cells Clonally Expanded in Rheumatoid Arthritis ¹

Takashi Namekawa; Melissa R. Snyder; Jeng-Hsien Yen; Brenda E. Goehring; Paul J. Leibson; Cornelia M. Weyand; Jörg J. Goronzy

J Immunol (2000) 165 (2): 1138–1145.

Abstract

View articletitled, Killer Cell Activating Receptors Function as Costimulatory Molecules on CD4+CD28null T Cells Clonally Expanded in Rheumatoid Arthritis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Long Term Persistence of Herpes Simplex Virus-Specific CD8⁺ CTL in Persons with Frequently Recurring Genital Herpes ¹

Christine M. Posavad; Meei Li Huang; Serge Barcy; David M. Koelle; Lawrence Corey

J Immunol (2000) 165 (2): 1146–1152.

Abstract

View articletitled, Long Term Persistence of Herpes Simplex Virus-Specific CD8+ CTL in Persons with Frequently Recurring Genital Herpes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of CD4⁺ T Cell Epitopes from NY-ESO-1 Presented by HLA-DR Molecules

Gang Zeng; Christopher E. Touloukian; Xiang Wang; Nicholas P. Restifo; Steven A. Rosenberg; Rong-Fu Wang

J Immunol (2000) 165 (2): 1153–1159.

Abstract

View articletitled, Identification of CD4+ T Cell Epitopes from NY-ESO-1 Presented by HLA-DR Molecules

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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