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15 February 2001
ISSN 0022-1767
EISSN 1550-6606
CUTTING EDGE
Cutting Edge: Peripheral Neuropeptides Attract Immature and Arrest Mature Blood-Derived Dendritic Cells1
J Immunol (2001) 166 (4): 2167–2172.
Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production1
J Immunol (2001) 166 (4): 2173–2177.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
The Microenvironment of Human Peyer’s Patches Inhibits the Increase in CD38 Expression Associated with the Germinal Center Reaction
J Immunol (2001) 166 (4): 2179–2185.
The Growth of the Very Large CD8+ T Cell Clones in Older Mice Is Controlled by Cytokines1
J Immunol (2001) 166 (4): 2186–2193.
Human Thymic Epithelial Cells Inhibit IL-15- and IL-2-Driven Differentiation of NK Cells from the Early Human Thymic Progenitors1
J Immunol (2001) 166 (4): 2194–2201.
Monocytes Are Differentially Activated Through HLA-DR, -DQ, and -DP Molecules Via Mitogen-Activated Protein Kinases1
J Immunol (2001) 166 (4): 2202–2208.
Activated p56lck Directs Maturation of Both CD4 and CD8 Single-Positive Thymocytes1
J Immunol (2001) 166 (4): 2209–2217.
NF-κB/Rel Participation in the Lymphokine-Dependent Proliferation of T Lymphoid Cells1
J Immunol (2001) 166 (4): 2218–2227.
Signals That Initiate Somatic Hypermutation of B Cells In Vitro1
Sigridur Bergthorsdottir; Aoife Gallagher; Sandra Jainandunsing; Debra Cockayne; James Sutton; Tomas Leanderson; David Gray
J Immunol (2001) 166 (4): 2228–2234.
Diverse Repertoire of the MHC Class II-Peptide Complexes Is Required for Presentation of Viral Superantigens1
J Immunol (2001) 166 (4): 2244–2250.
αβTCRs Differ in the Degree of Their Specificity for the Positively Selecting MHC/Peptide Ligand1
J Immunol (2001) 166 (4): 2251–2259.
IFN-γ Regulation of Class II Transactivator Promoter IV in Macrophages and Microglia: Involvement of the Suppressors of Cytokine Signaling-1 Protein
J Immunol (2001) 166 (4): 2260–2269.
Effector Function of Resting T Cells: Activation of Synovial Fibroblasts1
Yuji Yamamura; Raj Gupta; Yoshitaka Morita; Xiaogang He; Rajiv Pai; Judith Endres; Andrew Freiberg; Kevin Chung; David A. Fox
J Immunol (2001) 166 (4): 2270–2275.
IFN-γ-Dependent Inhibition of Tumor Angiogenesis by Tumor-Infiltrating CD4+ T Cells Requires Tumor Responsiveness to IFN-γ1
J Immunol (2001) 166 (4): 2276–2282.
Vγ2 TCR Repertoire Overlap in Different Anatomical Compartments of Healthy, Unrelated Rhesus Macaques1
J Immunol (2001) 166 (4): 2296–2302.
T Cell Phenotypes of the Normal Nasal Mucosa: Induction of Th2 Cytokines and CCR3 Expression by IL-41
Stephen J. Till; Louise A. Jopling; Petra A. Wachholz; Rachel L. Robson; Shixin Qin; David P. Andrew; Lijun Wu; Joost van Neerven; Timothy J. Williams; Stephen R. Durham; Ian Sabroe
J Immunol (2001) 166 (4): 2303–2310.
Peripheral Deletion After Bone Marrow Transplantation with Costimulatory Blockade Has Features of Both Activation-Induced Cell Death and Passive Cell Death1
Thomas Wekerle; Josef Kurtz; Mohamed H. Sayegh; Hiroshi Ito; Andrew D. Wells; Steven Bensinger; Juanita Shaffer; Laurence A. Turka; Megan Sykes
J Immunol (2001) 166 (4): 2311–2316.
Lysophosphatidic Acid Receptor-Selective Effects on Jurkat T Cell Migration Through a Matrigel Model Basement Membrane1
J Immunol (2001) 166 (4): 2317–2322.
CD4+ and CD8+ T Cell Priming for Contact Hypersensitivity Occurs Independently of CD40-CD154 Interactions1
J Immunol (2001) 166 (4): 2323–2332.
Ly-49W, an Activating Receptor of Nonobese Diabetic Mice With Close Homology to the Inhibitory Receptor Ly-49G, Recognizes H-2Dk and H-2Dd1
J Immunol (2001) 166 (4): 2333–2341.
Bacterial Lipopolysaccharide Activates HIV Long Terminal Repeat Through Toll-Like Receptor 41
J Immunol (2001) 166 (4): 2342–2347.
Direct Analysis of the Dynamics of the Intestinal Mucosa CD8 T Cell Response to Systemic Virus Infection1
J Immunol (2001) 166 (4): 2348–2356.
An Incremental Increase in the Complexity of Peptides Bound to Class II MHC Changes the Diversity of Positively Selected αβ TCRs
J Immunol (2001) 166 (4): 2357–2363.
Human Peripheral Blood Cells Differentially Recognize and Respond to Two Distinct CpG Motifs1 2
J Immunol (2001) 166 (4): 2372–2377.
Transactivation of C-Reactive Protein by IL-6 Requires Synergistic Interaction of CCAAT/Enhancer Binding Protein β (C/EBPβ) and Rel p501
J Immunol (2001) 166 (4): 2378–2384.
Viral IL-10-Induced Immunosuppression Requires Th2 Cytokines and Impairs APC Function Within the Allograft1
J Immunol (2001) 166 (4): 2385–2393.
A Critical Role for CD2 in Both Thymic Selection Events and Mature T Cell Function1
J Immunol (2001) 166 (4): 2394–2403.
Protection Against Diabetes and Improved NK/NKT Cell Performance in NOD.NK1.1 Mice Congenic at the NK Complex1
J Immunol (2001) 166 (4): 2404–2411.
Thrombospondin-1 Inhibits TCR-Mediated T Lymphocyte Early Activation
J Immunol (2001) 166 (4): 2427–2436.
Identification of a CD28 Response Element in the CD40 Ligand Promoter1
J Immunol (2001) 166 (4): 2437–2443.
Autologous Regulation of Naive T Cell Homeostasis Within the T Cell Compartment1
J Immunol (2001) 166 (4): 2460–2468.
Colocalization of FcγRI-Targeted Antigen With Class I MHC: Implications for Antigen Processing1
J Immunol (2001) 166 (4): 2469–2478.
A Novel Role of Complement: Mice Deficient in the Fifth Component of Complement (C5) Exhibit Impaired Liver Regeneration1
J Immunol (2001) 166 (4): 2479–2486.
Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements1
Frédéric Vely; Marie-Alix Peyrat; Christelle Couedel; Jean-François Morcet; Franck Halary; François Davodeau; François Romagne; Emmanuel Scotet; Xavier Saulquin; Elisabeth Houssaint; Nicolas Schleinitz; Alessandro Moretta; Eric Vivier; Marc Bonneville
J Immunol (2001) 166 (4): 2487–2494.
Comparison of a T Cell Clone and of T Cells from a TCR Transgenic Mouse: TCR Transgenic T Cells Specific for Self-Antigen Are Atypical1
J Immunol (2001) 166 (4): 2495–2504.
Acquisition of CD80 (B7-1) by T Cells
Helen Sabzevari; Judy Kantor; Adnan Jaigirdar; Yutaka Tagaya; Mayumi Naramura; James W. Hodge; John Bernon; Jeffrey Schlom
J Immunol (2001) 166 (4): 2505–2513.
Ig-Like Transcript 2 (ILT2)/Leukocyte Ig-Like Receptor 1 (LIR1) Inhibits TCR Signaling and Actin Cytoskeleton Reorganization1
J Immunol (2001) 166 (4): 2514–2521.
Selective Gene Expression and Activation-Dependent Regulation of Vasoactive Intestinal Peptide Receptor Type 1 and Type 2 in Human T Cells1
J Immunol (2001) 166 (4): 2522–2530.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Deletion of the DQ52 Element Within the Ig Heavy Chain Locus Leads to a Selective Reduction in VDJ Recombination and Altered D Gene Usage
J Immunol (2001) 166 (4): 2540–2552.
Cloning of Human Preprotachykinin-I Promoter and the Role of Cyclic Adenosine 5′-Monophosphate Response Elements in Its Expression by IL-1 and Stem Cell Factor1 2
Jing Qian; Ghassan Yehia; Carlos A. Molina; Annemarie Fernandes; Robert J. Donnelly; Devashish J. Anjaria; Pedro Gascon; Pranela Rameshwar
J Immunol (2001) 166 (4): 2553–2561.
The A′ and F′ Pockets of Human CD1b Are Both Required for Optimal Presentation of Lipid Antigens to T Cells1
Kayvan R. Niazi; Melvin W. Chiu; Richard M. Mendoza; Massimo Degano; Sumit Khurana; D. Branch Moody; Agustín Melián; Ian A. Wilson; Mitchell Kronenberg; Steven A. Porcelli; Robert L. Modlin
J Immunol (2001) 166 (4): 2562–2570.
Engineered Antibodies with Increased Activity to Recruit Complement
Esohe E. Idusogie; Pin Yee Wong; Leonard G. Presta; Helene Gazzano-Santoro; Klara Totpal; Mark Ultsch; Michael G. Mulkerrin
J Immunol (2001) 166 (4): 2571–2575.
A Particular TCR β Variable Region Used by T Cells Infiltrating Kidney Transplants1
J Immunol (2001) 166 (4): 2589–2596.
Ordered and Coordinated Rearrangement of the TCR α Locus: Role of Secondary Rearrangement in Thymic Selection1
J Immunol (2001) 166 (4): 2597–2601.
Human T Cell Lymphotropic Virus Type I Tax Activates IL-15Rα Gene Expression Through an NF-κB Site
J Immunol (2001) 166 (4): 2602–2609.
Mycoplasma fermentans Lipoprotein M161Ag-Induced Cell Activation Is Mediated by Toll-Like Receptor 2: Role of N-Terminal Hydrophobic Portion in its Multiple Functions1
Miyuki Nishiguchi; Misako Matsumoto; Toshifumi Takao; Masaru Hoshino; Yasutsugu Shimonishi; Shoutaro Tsuji; Nasim A. Begum; Osamu Takeuchi; Shizuo Akira; Kumao Toyoshima; Tsukasa Seya
J Immunol (2001) 166 (4): 2610–2616.
Reduction in DNA Binding Activity of the Transcription Factor Pax-5a in B Lymphocytes of Aged Mice1
J Immunol (2001) 166 (4): 2617–2626.
Fes Mediates the IL-4 Activation of Insulin Receptor Substrate-2 and Cellular Proliferation1
J Immunol (2001) 166 (4): 2627–2634.
Formation of High-Affinity C5 Convertases of the Alternative Pathway of Complement1
J Immunol (2001) 166 (4): 2635–2642.
HOST DEFENSE
Lipopolysaccharide-Induced IL-18 Secretion from Murine Kupffer Cells Independently of Myeloid Differentiation Factor 88 That Is Critically Involved in Induction of Production of IL-12 and IL-1β1
Ekihiro Seki; Hiroko Tsutsui; Hiroki Nakano; Noriko M. Tsuji; Katsuaki Hoshino; Osamu Adachi; Keishi Adachi; Shizue Futatsugi; Keisuke Kuida; Osamu Takeuchi; Haruki Okamura; Jiro Fujimoto; Shizuo Akira; Kenji Nakanishi
J Immunol (2001) 166 (4): 2651–2657.
A Role for IFN-αβ in Virus Infection-Induced Sensitization to Endotoxin1
J Immunol (2001) 166 (4): 2658–2664.
The WI-1 Adhesin Blocks Phagocyte TNF-α Production, Imparting Pathogenicity on Blastomyces dermatitidis1
J Immunol (2001) 166 (4): 2665–2673.
INFLAMMATION
IL-10 Is a Central Regulator of Cyclooxygenase-2 Expression and Prostaglandin Production1
J Immunol (2001) 166 (4): 2674–2680.
CXC Chemokine Receptor 4 Expression and Function in Human Astroglioma Cells1
J Immunol (2001) 166 (4): 2695–2704.
NF-κB Regulation by IκB Kinase-2 in Rheumatoid Arthritis Synoviocytes1
Karlfried R. Aupperle; Brydon L. Bennett; Zuoning Han; David L. Boyle; Anthony M. Manning; Gary S. Firestein
J Immunol (2001) 166 (4): 2705–2711.
IL-13 Overexpression Predisposes to Anaphylaxis Following Antigen Sensitization1
J Immunol (2001) 166 (4): 2712–2716.
Brain Dendritic Cells and Macrophages/Microglia in Central Nervous System Inflammation1
J Immunol (2001) 166 (4): 2717–2726.
Surfactant Protein A Enhances Alveolar Macrophage Phagocytosis of Apoptotic Neutrophils1
J Immunol (2001) 166 (4): 2727–2733.
Selective Inhibition of Inducible Nitric Oxide Synthase Exacerbates Erosive Joint Disease
J Immunol (2001) 166 (4): 2734–2740.
Expression of the Th1 Chemokine IFN-γ-Inducible Protein 10 in the Airway Alters Mucosal Allergic Sensitization in Mice1
Ryan E. Wiley; Kay Palmer; Beata U. Gajewska; Martin R. Stämpfli; David Alvarez; Anthony J. Coyle; José-Carlos Gutierrez-Ramos; Manel Jordana
J Immunol (2001) 166 (4): 2750–2759.
IL-4 and IL-13, But Not IL-10, Protect Human Synoviocytes from Apoptosis1
Biserka Relić; Jérome Guicheux; Françoise Mezin; Erik Lubberts; Danilo Togninalli; Irène Garcia; Wim B. van den Berg; Pierre-André Guerne
J Immunol (2001) 166 (4): 2775–2782.
Mast Cell Tissue Inhibitor of Metalloproteinase-1 Is Cleaved and Inactivated Extracellularly by α-Chymase1
J Immunol (2001) 166 (4): 2783–2792.
IL-4 Exacerbates Disease in a Th1 Cell Transfer Model of Colitis1
Madeline M. Fort; Robin Lesley; Natalie J. Davidson; Satish Menon; Frank Brombacher; Michael W. Leach; Donna M. Rennick
J Immunol (2001) 166 (4): 2793–2800.
CLINICAL IMMUNOLOGY
Serum Amyloid A (apoSAA) Expression Is Up-Regulated in Rheumatoid Arthritis and Induces Transcription of Matrix Metalloproteinases
Rüdiger Vallon; Felix Freuler; Netsanet Desta-Tsedu; Anna Robeva; Janet Dawson; Peter Wenner; Petra Engelhardt; Ludwig Boes; Jörg Schnyder; Claude Tschopp; Roman Urfer; Götz Baumann
J Immunol (2001) 166 (4): 2801–2807.
Effect of Thymectomy on Human Peripheral Blood T Cell Pools in Myasthenia Gravis
Gregory D. Sempowski; James R. Thomasch; Maria E. Gooding; Laura P. Hale; Lloyd J. Edwards; Emma Ciafaloni; Donald B. Sanders; Janice M. Massey; Daniel C. Douek; Richard A. Koup; Barton F. Haynes
J Immunol (2001) 166 (4): 2808–2817.
Blockade of TGF-β Signaling in T Cells Prevents the Development of Experimental Glomerulonephritis1
Yutaka Kanamaru; Atsuhito Nakao; Mizuko Mamura; Yusuke Suzuki; Isao Shirato; Ko Okumura; Yasuhiko Tomino; Chisei Ra
J Immunol (2001) 166 (4): 2818–2823.
Type I Diabetes and Multiple Sclerosis Patients Target Islet Plus Central Nervous System Autoantigens; Nonimmunized Nonobese Diabetic Mice Can Develop Autoimmune Encephalitis1
Shawn Winer; Igor Astsaturov; Roy K. Cheung; Lakshman Gunaratnam; Violetta Kubiak; Miguel A. Cortez; Mario Moscarello; Paul W. O’Connor; Colin McKerlie; Dorothy J. Becker; H.-Michael Dosch
J Immunol (2001) 166 (4): 2831–2841.
Vβ6+ and Vβ4+ T Cells Exert Cooperative Activity in Clearance of Secondary Infection with Histoplasma capsulatum1
J Immunol (2001) 166 (4): 2855–2862.
ERRATA
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