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EDITORIALS

The State of The Journal of Immunology—2001

Frank W. Fitch, M.D., Ph.D.; M. Michele Hogan; Ann M. Link

J Immunol (2001) 167 (4): 1853–1854.

View articletitled, The State of The Journal of Immunology—2001

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IN MEMORIUM

In Memorium Alfred Nisonoff 1923–2001

Lisa A. Steiner; Katherine L. Knight

J Immunol (2001) 167 (4): 1855–1856.

View articletitled, In Memorium Alfred Nisonoff 1923–2001

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CUTTING EDGE

Cutting Edge: T Cell Migration Regulated by CXCR4 Chemokine Receptor Signaling to ZAP-70 Tyrosine Kinase ¹

Nadine C. Ottoson; Jonathan T. Pribila; Anissa S. H. Chan; Yoji Shimizu

J Immunol (2001) 167 (4): 1857–1861.

Abstract

View articletitled, Cutting Edge: T Cell Migration Regulated by CXCR4 Chemokine Receptor Signaling to ZAP-70 Tyrosine Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells ¹

Giuseppe Penna; Silvano Sozzani; Luciano Adorini

J Immunol (2001) 167 (4): 1862–1866.

Abstract

View articletitled, Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Predominant Expression of a Novel Ikaros Isoform in Normal Human Hemopoiesis ¹

Kimberly J. Payne; Jan-Holly Nicolas; Judy Y. Zhu; Lora W. Barsky; Gay M. Crooks

J Immunol (2001) 167 (4): 1867–1870.

Abstract

View articletitled, Cutting Edge: Predominant Expression of a Novel Ikaros Isoform in Normal Human Hemopoiesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: The Nucleotide Receptor P2X₇ Contains Multiple Protein- and Lipid-Interaction Motifs Including a Potential Binding Site for Bacterial Lipopolysaccharide ¹

Loren C. Denlinger; Philip L. Fisette; Julie A. Sommer; Jyoti J. Watters; Usha Prabhu; George R. Dubyak; Richard A. Proctor; Paul J. Bertics

J Immunol (2001) 167 (4): 1871–1876.

Abstract

View articletitled, Cutting Edge: The Nucleotide Receptor P2X7 Contains Multiple Protein- and Lipid-Interaction Motifs Including a Potential Binding Site for Bacterial Lipopolysaccharide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Induction of IFN-γ Production but Not Cytotoxicity by the Killer Cell Ig-Like Receptor KIR2DL4 (CD158d) in Resting NK Cells

Sumati Rajagopalan; Jacqueline Fu; Eric O. Long

J Immunol (2001) 167 (4): 1877–1881.

Abstract

View articletitled, Cutting Edge: Induction of IFN-γ Production but Not Cytotoxicity by the Killer Cell Ig-Like Receptor KIR2DL4 (CD158d) in Resting NK Cells

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Cutting Edge: Bacterial Flagellin Activates Basolaterally Expressed TLR5 to Induce Epithelial Proinflammatory Gene Expression ¹

Andrew T. Gewirtz; Tony A. Navas; Sean Lyons; Paul J. Godowski; James L. Madara

J Immunol (2001) 167 (4): 1882–1885.

Abstract

View articletitled, Cutting Edge: Bacterial Flagellin Activates Basolaterally Expressed TLR5 to Induce Epithelial Proinflammatory Gene Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Expansion and Activation of A Population of Autoreactive Marginal Zone B Cells in a Model of Estrogen-Induced Lupus

Christine M. Grimaldi; Daniel J. Michael; Betty Diamond

J Immunol (2001) 167 (4): 1886–1890.

Abstract

View articletitled, Cutting Edge: Expansion and Activation of A Population of Autoreactive Marginal Zone B Cells in a Model of Estrogen-Induced Lupus

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Role of CD4⁺ and CD8⁺ T Cells in Allorecognition: Lessons from Corneal Transplantation ¹

Florence Boisgérault; Ying Liu; Natalie Anosova; Elana Ehrlich; M. Reza Dana; Gilles Benichou

J Immunol (2001) 167 (4): 1891–1899.

Abstract

View articletitled, Role of CD4+ and CD8+ T Cells in Allorecognition: Lessons from Corneal Transplantation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Cytomegalovirus Circumvents NF-κB Dependence in Retinal Pigment Epithelial Cells ¹

Jindrich Cinatl, Jr; Stefan Margraf; Jens-Uwe Vogel; Martin Scholz; Jaroslav Cinatl; Hans Wilhelm Doerr

J Immunol (2001) 167 (4): 1900–1908.

Abstract

View articletitled, Human Cytomegalovirus Circumvents NF-κB Dependence in Retinal Pigment Epithelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Essential Role of RelB in Germinal Center and Marginal Zone Formation and Proper Expression of Homing Chemokines ¹

Debra S. Weih; Z. Buket Yilmaz; Falk Weih

J Immunol (2001) 167 (4): 1909–1919.

Abstract

View articletitled, Essential Role of RelB in Germinal Center and Marginal Zone Formation and Proper Expression of Homing Chemokines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Signaling Through TNF Receptor p55 in TNF-α-Deficient Mice Alters the CXCL13/CCL19/CCL21 Ratio in the Spleen and Induces Maturation and Migration of Anergic B Cells into the B Cell Follicle ¹

Laura Mandik-Nayak; Guangming Huang; Kathleen C. F. Sheehan; Jan Erikson; David D. Chaplin

J Immunol (2001) 167 (4): 1920–1928.

Abstract

View articletitled, Signaling Through TNF Receptor p55 in TNF-α-Deficient Mice Alters the CXCL13/CCL19/CCL21 Ratio in the Spleen and Induces Maturation and Migration of Anergic B Cells into the B Cell Follicle<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Roles of Cytokine Receptors in the Development of Epidermal γδ T Cells ¹

Sang-Kyu Ye; Kazushige Maki; Hai-Chon Lee; Akiko Ito; Kazuhiro Kawai; Haruhiko Suzuki; Tak W. Mak; Yueh-hsiu Chien; Tasuku Honjo; Koichi Ikuta

J Immunol (2001) 167 (4): 1929–1934.

Abstract

View articletitled, Differential Roles of Cytokine Receptors in the Development of Epidermal γδ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Somatic Hypermutation and Selection of B Cells in Thymic Germinal Centers Responding to Acetylcholine Receptor in Myasthenia Gravis ¹

Gary P. Sims; Hiroyuki Shiono; Nick Willcox; David I. Stott

J Immunol (2001) 167 (4): 1935–1944.

Abstract

View articletitled, Somatic Hypermutation and Selection of B Cells in Thymic Germinal Centers Responding to Acetylcholine Receptor in Myasthenia Gravis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D₃ and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance ¹

Silvia Gregori; Mara Casorati; Susana Amuchastegui; Simona Smiroldo; Alberto M. Davalli; Luciano Adorini

J Immunol (2001) 167 (4): 1945–1953.

Abstract

View articletitled, Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Development of the Thymus Requires Signaling Through the Fibroblast Growth Factor Receptor R2-IIIb

Jean-Michel Revest; Ravinder K. Suniara; Karen Kerr; John J. T. Owen; Clive Dickson

J Immunol (2001) 167 (4): 1954–1961.

Abstract

View articletitled, Development of the Thymus Requires Signaling Through the Fibroblast Growth Factor Receptor R2-IIIb

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Impairment in the Expression and Activity of Fyn During Differentiation of Naive CD4⁺ T Cells into the Th2 Subset ¹

Toshiki Tamura; Osamu Igarashi; Ayako Hino; Hidehiro Yamane; Shinichi Aizawa; Takuma Kato; Hideo Nariuchi

J Immunol (2001) 167 (4): 1962–1969.

Abstract

View articletitled, Impairment in the Expression and Activity of Fyn During Differentiation of Naive CD4+ T Cells into the Th2 Subset<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Recent Thymic Emigrants–Identification, Expansion, And Survival Characteristics

Jaythoon Hassan; Denis J. Reen

J Immunol (2001) 167 (4): 1970–1976.

Abstract

View articletitled, Human Recent Thymic Emigrants–Identification, Expansion, And Survival Characteristics

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Impairment of Bleomycin-Induced Lung Fibrosis in CD28-Deficient Mice ¹

Tatsuma Okazaki; Atsuhito Nakao; Hiroyasu Nakano; Fumiyuki Takahashi; Kazuhisa Takahashi; Osamu Shimozato; Kazuyoshi Takeda; Hideo Yagita; Ko Okumura

J Immunol (2001) 167 (4): 1977–1981.

Abstract

View articletitled, Impairment of Bleomycin-Induced Lung Fibrosis in CD28-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD8⁻ Dendritic Cell Activation Status Plays an Integral Role in Influencing Th2 Response Development ¹

Andrew S. MacDonald; Amy D. Straw; Beverley Bauman; Edward J. Pearce

J Immunol (2001) 167 (4): 1982–1988.

Abstract

View articletitled, CD8− Dendritic Cell Activation Status Plays an Integral Role in Influencing Th2 Response Development<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Signaling Lymphocytic Activation Molecule Is Expressed on Mature CD83⁺ Dendritic Cells and Is Up-Regulated by IL-1β ¹

Monika Kruse; Edgar Meinl; Golo Henning; Christine Kuhnt; Susanne Berchtold; Thomas Berger; Gerold Schuler; Alexander Steinkasserer

J Immunol (2001) 167 (4): 1989–1995.

Abstract

View articletitled, Signaling Lymphocytic Activation Molecule Is Expressed on Mature CD83+ Dendritic Cells and Is Up-Regulated by IL-1β<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inducible Costimulator Regulates Th2-Mediated Inflammation, but Not Th2 Differentiation, in a Model of Allergic Airway Disease ¹

Amanda G. Tesciuba; Sumit Subudhi; Russell P. Rother; Susan J. Faas; Aric M. Frantz; David Elliot; Joel Weinstock; Louis A. Matis; Jeffrey A. Bluestone; Anne I. Sperling

J Immunol (2001) 167 (4): 1996–2003.

Abstract

View articletitled, Inducible Costimulator Regulates Th2-Mediated Inflammation, but Not Th2 Differentiation, in a Model of Allergic Airway Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Source of Early IFN-γ That Plays a Role in Th1 Priming ¹

Gobardhan Das; Scott Sheridan; Charles A. Janeway, Jr.

J Immunol (2001) 167 (4): 2004–2010.

Abstract

View articletitled, The Source of Early IFN-γ That Plays a Role in Th1 Priming<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ-Dependent and -Independent Initiation of Switch Recombination by NK Cells ¹

Ning Gao; Tam Dang; Dorothy Yuan

J Immunol (2001) 167 (4): 2011–2018.

Abstract

View articletitled, IFN-γ-Dependent and -Independent Initiation of Switch Recombination by NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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EBV-Specific CD8⁺ T Cell Memory: Relationships Between Epitope Specificity, Cell Phenotype, and Immediate Effector Function ¹

Andrew D. Hislop; Nancy H. Gudgeon; Margaret F. C. Callan; Chrysoula Fazou; Hitoshi Hasegawa; Michael Salmon; Alan B. Rickinson

J Immunol (2001) 167 (4): 2019–2029.

Abstract

View articletitled, EBV-Specific CD8+ T Cell Memory: Relationships Between Epitope Specificity, Cell Phenotype, and Immediate Effector Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Adaptive Tolerance of CD4⁺ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation

Corinne Tanchot; Daniel L. Barber; Lynda Chiodetti; Ronald H. Schwartz

J Immunol (2001) 167 (4): 2030–2039.

Abstract

View articletitled, Adaptive Tolerance of CD4+ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation

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Signaling Alterations in Activation-Induced Nonresponsive CD8 T Cells ¹

Ee Loon Tham; Matthew F. Mescher

J Immunol (2001) 167 (4): 2040–2048.

Abstract

View articletitled, Signaling Alterations in Activation-Induced Nonresponsive CD8 T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Nicotinamide Adenine Dinucleotide (NAD) and Its Metabolites Inhibit T Lymphocyte Proliferation: Role of Cell Surface NAD Glycohydrolase and Pyrophosphatase Activities ¹

Rita Bortell; Joel Moss; Robert C. McKenna; Mark R. Rigby; Dena Niedzwiecki; Linda A. Stevens; Walter A. Patton; John P. Mordes; Dale L. Greiner; Aldo A. Rossini

J Immunol (2001) 167 (4): 2049–2059.

Abstract

View articletitled, Nicotinamide Adenine Dinucleotide (NAD) and Its Metabolites Inhibit T Lymphocyte Proliferation: Role of Cell Surface NAD Glycohydrolase and Pyrophosphatase Activities<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Testosterone Acts Directly on CD4⁺ T Lymphocytes to Increase IL-10 Production ¹

Stephanie M. Liva; Rhonda R. Voskuhl

J Immunol (2001) 167 (4): 2060–2067.

Abstract

View articletitled, Testosterone Acts Directly on CD4+ T Lymphocytes to Increase IL-10 Production<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Central Role for Death Receptor-Mediated Apoptosis in the Rejection of Tumors by NK Cells ¹

Valentina Screpanti; Robert P. A. Wallin; Hans-Gustaf Ljunggren; Alf Grandien

J Immunol (2001) 167 (4): 2068–2073.

Abstract

View articletitled, A Central Role for Death Receptor-Mediated Apoptosis in the Rejection of Tumors by NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Adenosine 3′,5′-Cyclic Monophosphate (cAMP)-Dependent Inhibition of IL-5 from Human T Lymphocytes Is Not Mediated by the cAMP-Dependent Protein Kinase A ¹

Karl J. Staples; Martin Bergmann; Katsuyuki Tomita; Miles D. Houslay; Ian McPhee; Peter J. Barnes; Mark A. Giembycz; Robert Newton

J Immunol (2001) 167 (4): 2074–2080.

Abstract

View articletitled, Adenosine 3′,5′-Cyclic Monophosphate (cAMP)-Dependent Inhibition of IL-5 from Human T Lymphocytes Is Not Mediated by the cAMP-Dependent Protein Kinase A<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-17 Mobilizes Peripheral Blood Stem Cells with Short- and Long-Term Repopulating Ability in Mice ¹

Paul Schwarzenberger; Weitao Huang; Peter Oliver; Patrick Byrne; Vincent La Russa; Zili Zhang; Jay K. Kolls

J Immunol (2001) 167 (4): 2081–2086.

Abstract

View articletitled, IL-17 Mobilizes Peripheral Blood Stem Cells with Short- and Long-Term Repopulating Ability in Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Predominance of NK1.1⁺TCRαβ⁺ or DX5⁺TCRαβ⁺ T Cells in Mice Conditioned with Fractionated Lymphoid Irradiation Protects Against Graft-Versus-Host Disease: “Natural Suppressor” Cells ¹

Fengshuo Lan; Defu Zeng; Masanori Higuchi; Philip Huie; John P. Higgins; Samuel Strober

J Immunol (2001) 167 (4): 2087–2096.

Abstract

View articletitled, Predominance of NK1.1+TCRαβ+ or DX5+TCRαβ+ T Cells in Mice Conditioned with Fractionated Lymphoid Irradiation Protects Against Graft-Versus-Host Disease: “Natural Suppressor” Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Tapasin Enhances Peptide-Induced Expression of H2-M3 Molecules, but Is Not Required for the Retention of Open Conformers ¹

Lonnie Lybarger; Yik Yeung L. Yu; Taehoon Chun; Chyung-Ru Wang; Andres G. Grandea, III; Luc Van Kaer; Ted H. Hansen

J Immunol (2001) 167 (4): 2097–2105.

Abstract

View articletitled, Tapasin Enhances Peptide-Induced Expression of H2-M3 Molecules, but Is Not Required for the Retention of Open Conformers<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

A Point Mutation in the IL-12Rβ2 Gene Underlies the IL-12 Unresponsiveness of Lps-Defective C57BL/10ScCr Mice ¹

Alexander Poltorak; Thomas Merlin; Peter J. Nielsen; Olivier Sandra; Irina Smirnova; Ingo Schupp; Thomas Boehm; Chris Galanos; Marina A. Freudenberg

J Immunol (2001) 167 (4): 2106–2111.

Abstract

View articletitled, A Point Mutation in the IL-12Rβ2 Gene Underlies the IL-12 Unresponsiveness of Lps-Defective C57BL/10ScCr Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Isolation and Characterization of a Novel IgD-Binding Protein from Moraxella catarrhalis¹

Arne Forsgren; Marta Brant; Andrea Möllenkvist; Anthony Muyombwe; Håkan Janson; Nicolas Woin; Kristian Riesbeck

J Immunol (2001) 167 (4): 2112–2120.

Abstract

View articletitled, Isolation and Characterization of a Novel IgD-Binding Protein from Moraxella catarrhalis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distinct Control of the Frequency and Allelic Exclusion of the Vβ Gene Rearrangement at the TCRβ Locus ¹

Ping Sieh; Jianzhu Chen

J Immunol (2001) 167 (4): 2121–2129.

Abstract

View articletitled, Distinct Control of the Frequency and Allelic Exclusion of the Vβ Gene Rearrangement at the TCRβ Locus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands ¹

Yingdong Zhao; Bruno Gran; Clemencia Pinilla; Silva Markovic-Plese; Bernhard Hemmer; Abraham Tzou; Laurie Ward Whitney; William E. Biddison; Roland Martin; Richard Simon

J Immunol (2001) 167 (4): 2130–2141.

Abstract

View articletitled, Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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SCID in Jack Russell Terriers: A New Animal Model of DNA-PKcs Deficiency ¹

Katheryn Meek; Laura Kienker; Clarissa Dallas; Wei Wang; Michael J. Dark; Patrick J. Venta; Maryann L. Huie; Rochelle Hirschhorn; Tom Bell

J Immunol (2001) 167 (4): 2142–2150.

Abstract

View articletitled, SCID in Jack Russell Terriers: A New Animal Model of DNA-PKcs Deficiency<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Circulating Human B Cells That Express Surrogate Light Chains Display a Unique Antibody Repertoire ¹

Eric Meffre; Michael Chiorazzi; Michel C. Nussenzweig

J Immunol (2001) 167 (4): 2151–2156.

Abstract

View articletitled, Circulating Human B Cells That Express Surrogate Light Chains Display a Unique Antibody Repertoire<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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E2A and HEB Activate the Pre-TCRα Promoter During Immature T Cell Development ¹

Arata Takeuchi; Sho Yamasaki; Kan Takase; Fubito Nakatsu; Hisashi Arase; Makoto Onodera; Takashi Saito

J Immunol (2001) 167 (4): 2157–2163.

Abstract

View articletitled, E2A and HEB Activate the Pre-TCRα Promoter During Immature T Cell Development<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of the Active Sites in Decay-Accelerating Factor ¹

Lisa A. Kuttner-Kondo; Lynne Mitchell; Dennis E. Hourcade; M. Edward Medof

J Immunol (2001) 167 (4): 2164–2171.

Abstract

View articletitled, Characterization of the Active Sites in Decay-Accelerating Factor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Cathepsin W, a Cysteine Protease Predominantly Expressed in NK Cells, Is Mainly Localized in the Endoplasmic Reticulum ¹

Thomas Wex; Frank Bühling; Heike Wex; Dagmar Günther; Peter Malfertheiner; Ekkehard Weber; Dieter Brömme

J Immunol (2001) 167 (4): 2172–2178.

Abstract

View articletitled, Human Cathepsin W, a Cysteine Protease Predominantly Expressed in NK Cells, Is Mainly Localized in the Endoplasmic Reticulum<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mutation of a Single Conserved Residue in V_H Complementarity-Determining Region 2 Results in a Severe Ig Secretion Defect ¹

Gregory D. Wiens; Annemarie Lekkerkerker; Imke Veltman; Marvin B. Rittenberg

J Immunol (2001) 167 (4): 2179–2186.

Abstract

View articletitled, Mutation of a Single Conserved Residue in VH Complementarity-Determining Region 2 Results in a Severe Ig Secretion Defect<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Mycobacterial Lysocardiolipin Is Exported from Phagosomes upon Cleavage of Cardiolipin by a Macrophage-Derived Lysosomal Phospholipase A₂ ¹

Karsten Fischer; Delphi Chatterjee; Jordi Torrelles; Patrick J. Brennan; Stefan H. E. Kaufmann; Ulrich E. Schaible

J Immunol (2001) 167 (4): 2187–2192.

Abstract

View articletitled, Mycobacterial Lysocardiolipin Is Exported from Phagosomes upon Cleavage of Cardiolipin by a Macrophage-Derived Lysosomal Phospholipase A2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Toxoplasma gondii Tachyzoites Inhibit Proinflammatory Cytokine Induction in Infected Macrophages by Preventing Nuclear Translocation of the Transcription Factor NF-κB ¹

Barbara A. Butcher; Leesun Kim; Peter F. Johnson; Eric Y. Denkers

J Immunol (2001) 167 (4): 2193–2201.

Abstract

View articletitled, Toxoplasma gondii Tachyzoites Inhibit Proinflammatory Cytokine Induction in Infected Macrophages by Preventing Nuclear Translocation of the Transcription Factor NF-κB<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of TNF-α by Herpes Simplex Virus-Infected Macrophages Is Regulated by a Dual Mechanism: Transcriptional Regulation by NF-κB and Activating Transcription Factor 2/Jun and Translational Regulation Through the AU-Rich Region of the 3′ Untranslated Region ¹

Søren R. Paludan; Svend Ellermann-Eriksen; Veronique Kruys; Søren C. Mogensen

J Immunol (2001) 167 (4): 2202–2208.

Abstract

View articletitled, Expression of TNF-α by Herpes Simplex Virus-Infected Macrophages Is Regulated by a Dual Mechanism: Transcriptional Regulation by NF-κB and Activating Transcription Factor 2/Jun and Translational Regulation Through the AU-Rich Region of the 3′ Untranslated Region<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dynamic Antigen Presentation Patterns of Listeria monocytogenes-Derived CD8 T Cell Epitopes In Vivo ¹

Mojca Škoberne; Rafaela Holtappels; Herbert Hof; Gernot Geginat

J Immunol (2001) 167 (4): 2209–2218.

Abstract

View articletitled, Dynamic Antigen Presentation Patterns of Listeria monocytogenes-Derived CD8 T Cell Epitopes In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vβ6⁺ T Cells Are Obligatory for Vaccine-Induced Immunity to Histoplasma capsulatum¹

George S. Deepe, Jr.; Reta Gibbons

J Immunol (2001) 167 (4): 2219–2226.

Abstract

View articletitled, Vβ6+ T Cells Are Obligatory for Vaccine-Induced Immunity to Histoplasma capsulatum<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Transitions in Macrophages During In Vivo Infection with Mycobacterium bovis Bacillus Calmette-Guérin ¹

Jessica A. Hamerman; Alan Aderem

J Immunol (2001) 167 (4): 2227–2233.

Abstract

View articletitled, Functional Transitions in Macrophages During In Vivo Infection with Mycobacterium bovis Bacillus Calmette-Guérin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of IL-4 in Heligmosomoides polygyrus-Induced Alterations in Murine Intestinal Epithelial Cell Function ¹

Terez Shea-Donohue; Carolyn Sullivan; Fred D. Finkelman; Kathleen B. Madden; Suzanne C. Morris; Jon Goldhill; Victor Piñeiro-Carrero; Joseph F. Urban, Jr.

J Immunol (2001) 167 (4): 2234–2239.

Abstract

View articletitled, The Role of IL-4 in Heligmosomoides polygyrus-Induced Alterations in Murine Intestinal Epithelial Cell Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Targeting of Pseudomonas aeruginosa in the Bloodstream with Bispecific Monoclonal Antibodies ¹

Margaret A. Lindorfer; Alessandra Nardin; Patricia L. Foley; Michael D. Solga; Alexander J. Bankovich; Edward N. Martin; Andrea L. Henderson; Carol W. Price; Edit Gyimesi; Colin P. Wozencraft; Joanna B. Goldberg; William M. Sutherland; Ronald P. Taylor

J Immunol (2001) 167 (4): 2240–2249.

Abstract

View articletitled, Targeting of Pseudomonas aeruginosa in the Bloodstream with Bispecific Monoclonal Antibodies<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Protective Roles of Mast Cells Against Enterobacterial Infection Are Mediated by Toll-Like Receptor 4 ¹

Volaluck Supajatura; Hiroko Ushio; Atsuhito Nakao; Ko Okumura; Chisei Ra; Hideoki Ogawa

J Immunol (2001) 167 (4): 2250–2256.

Abstract

View articletitled, Protective Roles of Mast Cells Against Enterobacterial Infection Are Mediated by Toll-Like Receptor 4<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Tolerance to Lipopolysaccharide and Mycobacterial Components in Chinese Hamster Ovary/CD14 Cells Is Not Affected by Overexpression of Toll-Like Receptors 2 or 4 ¹ ^²

Andrei E. Medvedev; Philipp Henneke; Andra Schromm; Egil Lien; Robin Ingalls; Matthew J. Fenton; Douglas T. Golenbock; Stefanie N. Vogel

J Immunol (2001) 167 (4): 2257–2267.

Abstract

View articletitled, Induction of Tolerance to Lipopolysaccharide and Mycobacterial Components in Chinese Hamster Ovary/CD14 Cells Is Not Affected by Overexpression of Toll-Like Receptors 2 or 4<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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INFLAMMATION

Differential Requirements for Core2 Glucosaminyltransferase for Endothelial L-Selectin Ligand Function In Vivo ¹

Markus Sperandio; S. Bradley Forlow; Jayant Thatte; Lesley G. Ellies; Jamey D. Marth; Klaus Ley

J Immunol (2001) 167 (4): 2268–2274.

Abstract

View articletitled, Differential Requirements for Core2 Glucosaminyltransferase for Endothelial L-Selectin Ligand Function In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Taurine Chloramine Inhibits Inducible Nitric Oxide Synthase and TNF-α Gene Expression in Activated Alveolar Macrophages: Decreased NF-κB Activation and IκB Kinase Activity ¹

Madhabi Barua; Yong Liu; Michael R. Quinn

J Immunol (2001) 167 (4): 2275–2281.

Abstract

View articletitled, Taurine Chloramine Inhibits Inducible Nitric Oxide Synthase and TNF-α Gene Expression in Activated Alveolar Macrophages: Decreased NF-κB Activation and IκB Kinase Activity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils ¹

Katsushi Miura; Sarbjit S. Saini; Gail Gauvreau; Donald W. MacGlashan, Jr

J Immunol (2001) 167 (4): 2282–2291.

Abstract

View articletitled, Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Eosinophil Tissue Recruitment to Sites of Allergic Inflammation in the Lung Is Platelet Endothelial Cell Adhesion Molecule Independent ¹

Marina Miller; K.-L. Paul Sung; William A. Muller; Jae Youn Cho; Mark Roman; Diego Castaneda; Jyothi Nayar; Thomas Condon; John Kim; P. Sriramarao; David H. Broide

J Immunol (2001) 167 (4): 2292–2297.

Abstract

View articletitled, Eosinophil Tissue Recruitment to Sites of Allergic Inflammation in the Lung Is Platelet Endothelial Cell Adhesion Molecule Independent<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Sensitized Mast Cells Migrate Toward the Agen: A Response Regulated by p38 Mitogen-Activated Protein Kinase and Rho-Associated Coiled-Coil-Forming Protein Kinase ¹

Tamotsu Ishizuka; Fumikazu Okajima; Mitsuteru Ishiwara; Kunihiko Iizuka; Isao Ichimonji; Tadayoshi Kawata; Hideo Tsukagoshi; Kunio Dobashi; Tsugio Nakazawa; Masatomo Mori

J Immunol (2001) 167 (4): 2298–2304.

Abstract

View articletitled, Sensitized Mast Cells Migrate Toward the Agen: A Response Regulated by p38 Mitogen-Activated Protein Kinase and Rho-Associated Coiled-Coil-Forming Protein Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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C5b-9 Terminal Complement Complex Protects Oligodendrocytes from Death by Regulating Bad Through Phosphatidylinositol 3-Kinase/Akt Pathway ¹

Lucian Soane; Hyun-Jun Cho; Florin Niculescu; Horea Rus; Moon L. Shin

J Immunol (2001) 167 (4): 2305–2311.

Abstract

View articletitled, C5b-9 Terminal Complement Complex Protects Oligodendrocytes from Death by Regulating Bad Through Phosphatidylinositol 3-Kinase/Akt Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Up-Regulation of IL-10R1 Expression Is Required to Render Human Neutrophils Fully Responsive to IL-10 ¹

Luca Crepaldi; Sara Gasperini; José A. Lapinet; Federica Calzetti; Cristina Pinardi; Ying Liu; Sandra Zurawski; René de Waal Malefyt; Kevin W. Moore; Marco A. Cassatella

J Immunol (2001) 167 (4): 2312–2322.

Abstract

View articletitled, Up-Regulation of IL-10R1 Expression Is Required to Render Human Neutrophils Fully Responsive to IL-10<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Real-Time Imaging of Vascular Endothelial-Cadherin During Leukocyte Transmigration Across Endothelium ¹

Sunil K. Shaw; Paul S. Bamba; Brandy N. Perkins; Francis W. Luscinskas

J Immunol (2001) 167 (4): 2323–2330.

Abstract

View articletitled, Real-Time Imaging of Vascular Endothelial-Cadherin During Leukocyte Transmigration Across Endothelium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Supplementary data

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Regulation of Class II Expression in Monocytic Cells after HIV-1 Infection ¹

Seth Rakoff-Nahoum; Houchu Chen; Thomas Kraus; Italas George; Erwin Oei; Max Tyorkin; Erez Salik; Prarthana Beuria; Kirk Sperber

J Immunol (2001) 167 (4): 2331–2342.

Abstract

View articletitled, Regulation of Class II Expression in Monocytic Cells after HIV-1 Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Catalytic Subunit of Protein Kinase A Is an Interacting Partner of the Inflammation-Responsive Transcription Factor Serum Amyloid A-Activating Factor-1 ¹

Bimal K. Ray; Jing Chen; Alpana Ray

J Immunol (2001) 167 (4): 2343–2348.

Abstract

View articletitled, Catalytic Subunit of Protein Kinase A Is an Interacting Partner of the Inflammation-Responsive Transcription Factor Serum Amyloid A-Activating Factor-1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Critical Role for Mouse CXC Chemokine(s) in Pulmonary Neutrophilia During Th Type 1-Dependent Airway Inflammation ¹

Akiko Takaoka; Yoshitaka Tanaka; Takemasa Tsuji; Takafumi Jinushi; Akihiko Hoshino; Yumiko Asakura; Yasuo Mita; Kazuhito Watanabe; Shiro Nakaike; Yuji Togashi; Toshiaki Koda; Kouji Matsushima; Takashi Nishimura

J Immunol (2001) 167 (4): 2349–2353.

Abstract

View articletitled, A Critical Role for Mouse CXC Chemokine(s) in Pulmonary Neutrophilia During Th Type 1-Dependent Airway Inflammation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

The Role of αβ⁺ T Cells and Homeostatic T Cell Proliferation in Y-Chromosome-Associated Murine Lupus ¹

Brian R. Lawson; Stefanos I. Koundouris; Marlene Barnhouse; Wolfgang Dummer; Roberto Baccala; Dwight H. Kono; Argyrios N. Theofilopoulos

J Immunol (2001) 167 (4): 2354–2360.

Abstract

View articletitled, The Role of αβ+ T Cells and Homeostatic T Cell Proliferation in Y-Chromosome-Associated Murine Lupus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus ¹

Edsel Arce; Deborah G. Jackson; Michelle A. Gill; Lynda B. Bennett; Jacques Banchereau; Virginia Pascual

J Immunol (2001) 167 (4): 2361–2369.

Abstract

View articletitled, Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fas/Fas Ligand Deficiency Results in Altered Localization of Anti-Double-Stranded DNA B Cells and Dendritic Cells ¹

Michele L. Fields; Caroline L. Sokol; Ashlyn Eaton-Bassiri; Su-jean Seo; Michael P. Madaio; Jan Erikson

J Immunol (2001) 167 (4): 2370–2378.

Abstract

View articletitled, Fas/Fas Ligand Deficiency Results in Altered Localization of Anti-Double-Stranded DNA B Cells and Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Adoptive Immunotherapy of Experimental Autoimmune Encephalomyelitis Via T Cell Delivery of the IL-12 p40 Subunit ¹

Gina L. Costa; Matthew R. Sandora; Atsuo Nakajima; Eddy V. Nguyen; Cariel Taylor-Edwards; Anthony J. Slavin; Christopher H. Contag; C. Garrison Fathman; Jacqueline M. Benson

J Immunol (2001) 167 (4): 2379–2387.

Abstract

View articletitled, Adoptive Immunotherapy of Experimental Autoimmune Encephalomyelitis Via T Cell Delivery of the IL-12 p40 Subunit<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Glomerulonephritis Induced by Recombinant Collagen IVα3 Chain Noncollagen Domain 1 Is Not Associated with Glomerular Basement Membrane Antibody: A Potential T Cell-Mediated Mechanism ¹

Jean Wu; John Hicks; Ching-nan Ou; David Singleton; Jason Borillo; Ya-Huan Lou

J Immunol (2001) 167 (4): 2388–2395.

Abstract

View articletitled, Glomerulonephritis Induced by Recombinant Collagen IVα3 Chain Noncollagen Domain 1 Is Not Associated with Glomerular Basement Membrane Antibody: A Potential T Cell-Mediated Mechanism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Resistance to Xenobiotic-Induced Autoimmunity Maps to Chromosome 1 ¹

Dwight H. Kono; Miyo S. Park; Agnieszka Szydlik; Katarina M. Haraldsson; Jason D. Kuan; Deborah L. Pearson; Per Hultman; K. Michael Pollard

J Immunol (2001) 167 (4): 2396–2403.

Abstract

View articletitled, Resistance to Xenobiotic-Induced Autoimmunity Maps to Chromosome 1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of Autoimmune Diabetes in Nonobese Diabetic Mice by Transgenic Restoration of H2-E MHC Class II Expression: Additive, But Unequal, Involvement of Multiple APC Subtypes ¹

Ellis A. Johnson; Pablo Silveira; Harold D. Chapman; Edward H. Leiter; David V. Serreze

J Immunol (2001) 167 (4): 2404–2410.

Abstract

View articletitled, Inhibition of Autoimmune Diabetes in Nonobese Diabetic Mice by Transgenic Restoration of H2-E MHC Class II Expression: Additive, But Unequal, Involvement of Multiple APC Subtypes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Down-Regulation of IgE and IgG4 Antibodies to Tetanus Toxoid and Diphtheria Toxoid by Covaccination with Cellular Bordetella pertussis Vaccine ¹

Christoph Grüber; Susanne Lau; Almut Dannemann; Christine Sommerfeld; Ulrich Wahn; Rob C. Aalberse

J Immunol (2001) 167 (4): 2411–2417.

Abstract

View articletitled, Down-Regulation of IgE and IgG4 Antibodies to Tetanus Toxoid and Diphtheria Toxoid by Covaccination with Cellular Bordetella pertussis Vaccine<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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ERRATA

CORRECTION

J Immunol (2001) 167 (4): 2418.

View articletitled, CORRECTION

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Issues

EDITORIALS

IN MEMORIUM

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

ERRATA

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