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CUTTING EDGE

Cutting Edge: Requirement for IL-15 in the Generation of Primary and Memory Antigen-Specific CD8 T Cells ¹

Kimberly S. Schluns; Kristina Williams; Averil Ma; Xin X. Zheng; Leo Lefrançois

J Immunol (2002) 168 (10): 4827–4831.

Abstract

View articletitled, Cutting Edge: Requirement for IL-15 in the Generation of Primary and Memory Antigen-Specific CD8 T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Selective Impairment of CD8⁺ T Cell Function in Mice Lacking the TNF Superfamily Member LIGHT

Koji Tamada; Jian Ni; Gefeng Zhu; Michele Fiscella; Baiqin Teng; Jan M. A. van Deursen; Lieping Chen

J Immunol (2002) 168 (10): 4832–4835.

Abstract

View articletitled, Cutting Edge: Selective Impairment of CD8+ T Cell Function in Mice Lacking the TNF Superfamily Member LIGHT

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Evidence for a Dual Mechanism for IL-10 Suppression of TNF-α Production That Does Not Involve Inhibition of p38 Mitogen-Activated Protein Kinase or NF-κB in Primary Human Macrophages ¹

Agnes Denys; Irina A. Udalova; Clive Smith; Lynn M. Williams; Cathleen J. Ciesielski; Jamie Campbell; Caroline Andrews; Dominic Kwaitkowski; Brian M. J. Foxwell

J Immunol (2002) 168 (10): 4837–4845.

Abstract

View articletitled, Evidence for a Dual Mechanism for IL-10 Suppression of TNF-α Production That Does Not Involve Inhibition of p38 Mitogen-Activated Protein Kinase or NF-κB in Primary Human Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Dendritic Cell Differentiation and Maturation by Decoy Receptor 3 ¹

Tsui-Ling Hsu; Yung-Chi Chang; Siu-Ju Chen; Yong-Jun Liu; Allen W. Chiu; Chung-Ching Chio; Lieping Chen; Shie-Liang Hsieh

J Immunol (2002) 168 (10): 4846–4853.

Abstract

View articletitled, Modulation of Dendritic Cell Differentiation and Maturation by Decoy Receptor 3<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunostimulatory CpG-DNA Activates Murine Microglia ¹

Alexander H. Dalpke; Martin K.-H. Schäfer; Markus Frey; Stefan Zimmermann; Johannes Tebbe; Eberhard Weihe; Klaus Heeg

J Immunol (2002) 168 (10): 4854–4863.

Abstract

View articletitled, Immunostimulatory CpG-DNA Activates Murine Microglia<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of CD94/NKG2-A on Human T Lymphocytes Is Induced by IL-12: Implications for Adoptive Immunotherapy ¹

Laurent Derre; Murielle Corvaisier; Marie-Christine Pandolfino; Elisabeth Diez; Francine Jotereau; Nadine Gervois

J Immunol (2002) 168 (10): 4864–4870.

Abstract

View articletitled, Expression of CD94/NKG2-A on Human T Lymphocytes Is Induced by IL-12: Implications for Adoptive Immunotherapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human B Cells Become Highly Responsive to Macrophage-Inflammatory Protein-3α/CC Chemokine Ligand-20 After Cellular Activation Without Changes in CCR6 Expression or Ligand Binding

Fang Liao; Aiko-Konno Shirakawa; John F. Foley; Ronald L. Rabin; Joshua M. Farber

J Immunol (2002) 168 (10): 4871–4880.

Abstract

View articletitled, Human B Cells Become Highly Responsive to Macrophage-Inflammatory Protein-3α/CC Chemokine Ligand-20 After Cellular Activation Without Changes in CCR6 Expression or Ligand Binding

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Death Ligand TRAIL Induces No Apoptosis but Inhibits Activation of Human (Auto)antigen-Specific T Cells ¹

Jan D. Lünemann; Sonia Waiczies; Stefan Ehrlich; Uwe Wendling; Bibiane Seeger; Thomas Kamradt; Frauke Zipp

J Immunol (2002) 168 (10): 4881–4888.

Abstract

View articletitled, Death Ligand TRAIL Induces No Apoptosis but Inhibits Activation of Human (Auto)antigen-Specific T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Vγ2Vδ2 T Cells Augment Migration-Inhibitory Factor Secretion and Counteract the Inhibitory Effect of Glucocorticoids on IL-1β and TNF-α Production ¹

Lisheng Wang; Hiranmoy Das; Arati Kamath; Lin Li; Jack F. Bukowski

J Immunol (2002) 168 (10): 4889–4896.

Abstract

View articletitled, Human Vγ2Vδ2 T Cells Augment Migration-Inhibitory Factor Secretion and Counteract the Inhibitory Effect of Glucocorticoids on IL-1β and TNF-α Production<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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4-1BB Ligand-Mediated Costimulation of Human T Cells Induces CD4 and CD8 T Cell Expansion, Cytokine Production, and the Development of Cytolytic Effector Function ¹

Tao Wen; Jacob Bukczynski; Tania H. Watts

J Immunol (2002) 168 (10): 4897–4906.

Abstract

View articletitled, 4-1BB Ligand-Mediated Costimulation of Human T Cells Induces CD4 and CD8 T Cell Expansion, Cytokine Production, and the Development of Cytolytic Effector Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-αβ Promote Priming of Antigen-Specific CD8⁺ and CD4⁺ T Lymphocytes by Immunostimulatory DNA-Based Vaccines ¹

Hearn Jay Cho; Tomoko Hayashi; Sandip K. Datta; Kenji Takabayashi; John Henry Van Uden; Anthony Horner; Maripat Corr; Eyal Raz

J Immunol (2002) 168 (10): 4907–4913.

Abstract

View articletitled, IFN-αβ Promote Priming of Antigen-Specific CD8+ and CD4+ T Lymphocytes by Immunostimulatory DNA-Based Vaccines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity ¹

Keith Dredge; J. Blake Marriott; Stephen M. Todryk; George W. Muller; Roger Chen; David I. Stirling; Angus G. Dalgleish

J Immunol (2002) 168 (10): 4914–4919.

Abstract

View articletitled, Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells ¹

Andrea Glatzel; Daniela Wesch; Florian Schiemann; Ernst Brandt; Ottmar Janssen; Dieter Kabelitz

J Immunol (2002) 168 (10): 4920–4929.

Abstract

View articletitled, Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Absence of Fer Protein-Tyrosine Kinase Exacerbates Leukocyte Recruitment in Response to Endotoxin ¹

Donna-Marie McCafferty; Andrew W. B. Craig; Yotis A. Senis; Peter A. Greer

J Immunol (2002) 168 (10): 4930–4935.

Abstract

View articletitled, Absence of Fer Protein-Tyrosine Kinase Exacerbates Leukocyte Recruitment in Response to Endotoxin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Sustained NFAT Signaling Promotes a Th1-Like Pattern of Gene Expression in Primary Murine CD4⁺ T Cells ¹

Cynthia M. Porter; Neil A. Clipstone

J Immunol (2002) 168 (10): 4936–4945.

Abstract

View articletitled, Sustained NFAT Signaling Promotes a Th1-Like Pattern of Gene Expression in Primary Murine CD4+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Role for CD147 in Thymic Development

Toufic Renno; Anne Wilson; Caroline Dunkel; Isabelle Coste; Karine Maisnier-Patin; Amélie Benoit de Coignac; Jean-Pierre Aubry; Rosemary K. Lees; Jean-Yves Bonnefoy; H. Robson MacDonald; Jean-François Gauchat

J Immunol (2002) 168 (10): 4946–4950.

Abstract

View articletitled, A Role for CD147 in Thymic Development

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Priming Th1 Immunity to Viral Core Particles Is Facilitated by Trace Amounts of RNA Bound to Its Arginine-Rich Domain ¹

Petra Riedl; Detlef Stober; Claude Oehninger; Karl Melber; Jörg Reimann; Reinhold Schirmbeck

J Immunol (2002) 168 (10): 4951–4959.

Abstract

View articletitled, Priming Th1 Immunity to Viral Core Particles Is Facilitated by Trace Amounts of RNA Bound to Its Arginine-Rich Domain<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fas-Dependent Elimination of Nonselected CD8 Cells and lpr Disease ¹

Linda A. Trimble; Kenya A. Prince; Gary A. Pestano; John Daley; Harvey Cantor

J Immunol (2002) 168 (10): 4960–4967.

Abstract

View articletitled, Fas-Dependent Elimination of Nonselected CD8 Cells and lpr Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Reevaluation of T Cell Receptor Excision Circles as a Measure of Human Recent Thymic Emigrants ¹

Ping Ye; Denise E. Kirschner

J Immunol (2002) 168 (10): 4968–4979.

Abstract

View articletitled, Reevaluation of T Cell Receptor Excision Circles as a Measure of Human Recent Thymic Emigrants<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Orderly and Nonstochastic Acquisition of CD94/NKG2 Receptors by Developing NK Cells Derived from Embryonic Stem Cells In Vitro ¹

Rebecca H. Lian; Motoi Maeda; Stefan Lohwasser; Marc Delcommenne; Toru Nakano; Russell E. Vance; David H. Raulet; Fumio Takei

J Immunol (2002) 168 (10): 4980–4987.

Abstract

View articletitled, Orderly and Nonstochastic Acquisition of CD94/NKG2 Receptors by Developing NK Cells Derived from Embryonic Stem Cells In Vitro<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Postgestational Lymphotoxin/Lymphotoxin β Receptor Interactions Are Essential for the Presence of Intestinal B Lymphocytes ¹

Rodney D. Newberry; Jacquelyn S. McDonough; Keely G. McDonald; Robin G. Lorenz

J Immunol (2002) 168 (10): 4988–4997.

Abstract

View articletitled, Postgestational Lymphotoxin/Lymphotoxin β Receptor Interactions Are Essential for the Presence of Intestinal B Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Optimizing the Efficacy of Epitope-Directed DNA Vaccination ¹

Monika C. Wolkers; Mireille Toebes; Masaru Okabe; John B. A. G. Haanen; Ton N. M. Schumacher

J Immunol (2002) 168 (10): 4998–5004.

Abstract

View articletitled, Optimizing the Efficacy of Epitope-Directed DNA Vaccination<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rat Peripheral CD4⁺CD8⁺ T Lymphocytes Are Partially Immunocompetent Thymus-Derived Cells That Undergo Post-Thymic Maturation to Become Functionally Mature CD4⁺ T Lymphocytes ¹

Eva Jiménez; Rosa Sacedón; Angeles Vicente; Carmen Hernández-López; Agustín G. Zapata; Alberto Varas

J Immunol (2002) 168 (10): 5005–5013.

Abstract

View articletitled, Rat Peripheral CD4+CD8+ T Lymphocytes Are Partially Immunocompetent Thymus-Derived Cells That Undergo Post-Thymic Maturation to Become Functionally Mature CD4+ T Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Aging-Dependent Exclusion of Antigen-Inexperienced Cells from the Peripheral B Cell Repertoire ¹

Sara A. Johnson; Stephen J. Rozzo; John C. Cambier

J Immunol (2002) 168 (10): 5014–5023.

Abstract

View articletitled, Aging-Dependent Exclusion of Antigen-Inexperienced Cells from the Peripheral B Cell Repertoire<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Forkhead Transcription Factor FoxO Regulates Transcription of p27^Kip1 and Bim in Response to IL-2 ¹

Marie Stahl; Pascale F. Dijkers; Geert J. P. L. Kops; Susanne M. A. Lens; Paul J. Coffer; Boudewijn M. T. Burgering; René H. Medema

J Immunol (2002) 168 (10): 5024–5031.

Abstract

View articletitled, The Forkhead Transcription Factor FoxO Regulates Transcription of p27Kip1 and Bim in Response to IL-2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Increased Generation of Dendritic Cells from Myeloid Progenitors in Autoimmune-Prone Nonobese Diabetic Mice ¹

Raymond J. Steptoe; Janine M. Ritchie; Leonard C. Harrison

J Immunol (2002) 168 (10): 5032–5041.

Abstract

View articletitled, Increased Generation of Dendritic Cells from Myeloid Progenitors in Autoimmune-Prone Nonobese Diabetic Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Conversion of Naive T Cells to a Memory-Like Phenotype in Lymphopenic Hosts Is Not Related to a Homeostatic Mechanism That Fills the Peripheral Naive T Cell Pool ¹

Corinne Tanchot; Armelle Le Campion; Bruno Martin; Sandrine Léaument; Nicole Dautigny; Bruno Lucas

J Immunol (2002) 168 (10): 5042–5046.

Abstract

View articletitled, Conversion of Naive T Cells to a Memory-Like Phenotype in Lymphopenic Hosts Is Not Related to a Homeostatic Mechanism That Fills the Peripheral Naive T Cell Pool<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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SHP-1- and Phosphotyrosine-Independent Inhibitory Signaling by a Killer Cell Ig-Like Receptor Cytoplasmic Domain in Human NK Cells ¹

Sei-ichi Yusa; Tracey L. Catina; Kerry S. Campbell

J Immunol (2002) 168 (10): 5047–5057.

Abstract

View articletitled, SHP-1- and Phosphotyrosine-Independent Inhibitory Signaling by a Killer Cell Ig-Like Receptor Cytoplasmic Domain in Human NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role for Thymic and Splenic Regulatory CD4⁺ T Cells Induced by Donor Dendritic Cells in Allograft Tolerance by LF15-0195 Treatment ¹

Elise Chiffoleau; Gaëlle Bériou; Patrick Dutartre; Claire Usal; Jean-Paul Soulillou; Maria Cristina Cuturi

J Immunol (2002) 168 (10): 5058–5069.

Abstract

View articletitled, Role for Thymic and Splenic Regulatory CD4+ T Cells Induced by Donor Dendritic Cells in Allograft Tolerance by LF15-0195 Treatment<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of CTLA-4 Function by the Regulatory Subunit of Serine/Threonine Phosphatase 2A ¹

Miren L. Baroja; Lalitha Vijayakrishnan; Estelle Bettelli; Peter J. Darlington; Thu A. Chau; Vincent Ling; Mary Collins; Beatriz M. Carreno; Joaquín Madrenas; Vijay K. Kuchroo

J Immunol (2002) 168 (10): 5070–5078.

Abstract

View articletitled, Inhibition of CTLA-4 Function by the Regulatory Subunit of Serine/Threonine Phosphatase 2A<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Visualization of Lymphotoxin-β and Lymphotoxin-β Receptor Expression in Mouse Embryos ¹

Jeffrey L. Browning; Lars E. French

J Immunol (2002) 168 (10): 5079–5087.

Abstract

View articletitled, Visualization of Lymphotoxin-β and Lymphotoxin-β Receptor Expression in Mouse Embryos<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Different Qualitative and Quantitative Regulation of Vβ TCR Transcripts During Early Acute Allograft Rejection and Tolerance Induction ¹

Marina Guillet; Sophie Brouard; Katia Gagne; Fabien Sébille; Maria-Cristina Cuturi; Marc-André Delsuc; Jean-Paul Soulillou

J Immunol (2002) 168 (10): 5088–5095.

Abstract

View articletitled, Different Qualitative and Quantitative Regulation of Vβ TCR Transcripts During Early Acute Allograft Rejection and Tolerance Induction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CXCR5-Transduced Bone Marrow-Derived Dendritic Cells Traffic to B Cell Zones of Lymph Nodes and Modify Antigen-Specific Immune Responses

Meng-Tse Wu; Sam T. Hwang

J Immunol (2002) 168 (10): 5096–5102.

Abstract

View articletitled, CXCR5-Transduced Bone Marrow-Derived Dendritic Cells Traffic to B Cell Zones of Lymph Nodes and Modify Antigen-Specific Immune Responses

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IL-1 Regulates Cytoskeletal Organization in Osteoclasts Via TNF Receptor-Associated Factor 6/c-Src Complex ¹

Ichiro Nakamura; Yuho Kadono; Hiroshi Takayanagi; Eijiro Jimi; Tsuyoshi Miyazaki; Hiromi Oda; Kozo Nakamura; Sakae Tanaka; Gideon A. Rodan; Le T. Duong

J Immunol (2002) 168 (10): 5103–5109.

Abstract

View articletitled, IL-1 Regulates Cytoskeletal Organization in Osteoclasts Via TNF Receptor-Associated Factor 6/c-Src Complex<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Adapter Molecule Grb2-Associated Binder 1 Is Specifically Expressed in Marginal Zone B Cells and Negatively Regulates Thymus-Independent Antigen-2 Responses ¹

Shousaku Itoh; Motoyuki Itoh; Keigo Nishida; Satoru Yamasaki; Yuichi Yoshida; Masahiro Narimatsu; Sung Joo Park; Masahiko Hibi; Katsuhiko Ishihara; Toshio Hirano

J Immunol (2002) 168 (10): 5110–5116.

Abstract

View articletitled, Adapter Molecule Grb2-Associated Binder 1 Is Specifically Expressed in Marginal Zone B Cells and Negatively Regulates Thymus-Independent Antigen-2 Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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B Cells Control the Migration of a Subset of Dendritic Cells into B Cell Follicles Via CXC Chemokine Ligand 13 in a Lymphotoxin-Dependent Fashion ¹

Ping Yu; Yang Wang; Robert K. Chin; Luisa Martinez-Pomares; Siamon Gordon; Marie H. Kosco-Vibois; Jason Cyster; Yang-Xin Fu

J Immunol (2002) 168 (10): 5117–5123.

Abstract

View articletitled, B Cells Control the Migration of a Subset of Dendritic Cells into B Cell Follicles Via CXC Chemokine Ligand 13 in a Lymphotoxin-Dependent Fashion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD40 Ligation in the Presence of Self-Reactive CD8 T Cells Leads to Severe Immunopathology ¹

Evelyn Roth; Johannes Schwartzkopff; Hanspeter Pircher

J Immunol (2002) 168 (10): 5124–5129.

Abstract

View articletitled, CD40 Ligation in the Presence of Self-Reactive CD8 T Cells Leads to Severe Immunopathology<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

The Human V-PreB Promoter Is a Target for Coordinated Activation by Early B Cell Factor and E47 ¹

Ramiro Gisler; Mikael Sigvardsson

J Immunol (2002) 168 (10): 5130–5138.

Abstract

View articletitled, The Human V-PreB Promoter Is a Target for Coordinated Activation by Early B Cell Factor and E47<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Expression and Signaling in Human, Mouse, and Rat Leukocytes: Evidence for Replacement of the Short Cytoplasmic Domain Isoform by Glycosylphosphatidylinositol-Linked Proteins in Human Leukocytes ¹

Bernhard B. Singer; Inka Scheffrahn; Robert Heymann; Kristmundur Sigmundsson; Robert Kammerer; Björn Öbrink

J Immunol (2002) 168 (10): 5139–5146.

Abstract

View articletitled, Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Expression and Signaling in Human, Mouse, and Rat Leukocytes: Evidence for Replacement of the Short Cytoplasmic Domain Isoform by Glycosylphosphatidylinositol-Linked Proteins in Human Leukocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of a Novel Killer Cell Lectin-Like Receptor (KLRH1) Expressed by Alloreactive Rat NK Cells ¹

Christian Naper; Shigenari Hayashi; Guro Løvik; Lise Kveberg; Eréne C. Niemi; Bent Rolstad; Erik Dissen; James C. Ryan; John T. Vaage

J Immunol (2002) 168 (10): 5147–5154.

Abstract

View articletitled, Characterization of a Novel Killer Cell Lectin-Like Receptor (KLRH1) Expressed by Alloreactive Rat NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Heavy Chain V Region Diversity in the Duck-Billed Platypus (Ornithorhynchus anatinus): Long and Highly Variable Complementarity-Determining Region 3 Compensates for Limited Germline Diversity ¹

Jeannette Johansson; Maria Aveskogh; Barry Munday; Lars Hellman

J Immunol (2002) 168 (10): 5155–5162.

Abstract

View articletitled, Heavy Chain V Region Diversity in the Duck-Billed Platypus (Ornithorhynchus anatinus): Long and Highly Variable Complementarity-Determining Region 3 Compensates for Limited Germline Diversity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of a Novel Ly49 Promoter That Is Active in Bone Marrow and Fetal Thymus ¹

Ali Saleh; Andrew P. Makrigiannis; Deborah L. Hodge; Stephen K. Anderson

J Immunol (2002) 168 (10): 5163–5169.

Abstract

View articletitled, Identification of a Novel Ly49 Promoter That Is Active in Bone Marrow and Fetal Thymus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity ¹

Camie W. Y. Chan; Matthew W. C. Chan; Mingfeng Liu; Laisum Fung; Edward H. Cole; Julian L. Leibowitz; Philip A. Marsden; David A. Clark; Gary A. Levy

J Immunol (2002) 168 (10): 5170–5177.

Abstract

View articletitled, Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Heat Shock Protein 47 Synthesis by TGF-β and IL-1β Via Enhancement of the Heat Shock Element Binding Activity of Heat Shock Transcription Factor 1

Hiroyoshi Sasaki; Tsutomu Sato; Naofumi Yamauchi; Tetsuro Okamoto; Daisuke Kobayashi; Satoshi Iyama; Junji Kato; Takuya Matsunaga; Rishu Takimoto; Tetsuji Takayama; Katsuhisa Kogawa; Naoki Watanabe; Yoshiro Niitsu

J Immunol (2002) 168 (10): 5178–5183.

Abstract

View articletitled, Induction of Heat Shock Protein 47 Synthesis by TGF-β and IL-1β Via Enhancement of the Heat Shock Element Binding Activity of Heat Shock Transcription Factor 1

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HOST DEFENSE

Antigenic Topology of Chlamydial PorB Protein and Identification of Targets for Immune Neutralization of Infectivity ¹

Diane E. Kawa; Richard S. Stephens

J Immunol (2002) 168 (10): 5184–5191.

Abstract

View articletitled, Antigenic Topology of Chlamydial PorB Protein and Identification of Targets for Immune Neutralization of Infectivity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Costimulation of Host T Lymphocytes by a Trypanosomal trans-Sialidase: Involvement of CD43 Signaling ¹

Adriane R. Todeschini; Marise P. Nunes; Rachel S. Pires; Marcela F. Lopes; José O. Previato; Lúcia Mendonça-Previato; George A. DosReis

J Immunol (2002) 168 (10): 5192–5198.

Abstract

View articletitled, Costimulation of Host T Lymphocytes by a Trypanosomal trans-Sialidase: Involvement of CD43 Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expansion of NK Cells with Reduction of Their Inhibitory Ly-49A, Ly-49C, and Ly-49G2 Receptor-Expressing Subsets in a Murine Helminth Infection: Contribution to Parasite Control ¹

Simone Korten; Lars Volkmann; Michael Saeftel; Kerstin Fischer; Masaru Taniguchi; Bernhard Fleischer; Achim Hoerauf

J Immunol (2002) 168 (10): 5199–5206.

Abstract

View articletitled, Expansion of NK Cells with Reduction of Their Inhibitory Ly-49A, Ly-49C, and Ly-49G2 Receptor-Expressing Subsets in a Murine Helminth Infection: Contribution to Parasite Control<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Critical Role of Signaling Through IL-1 Receptor for Development of Arthritis and Sepsis During Staphylococcus aureus Infection ¹

Olof H. Hultgren; Lena Svensson; Andrej Tarkowski

J Immunol (2002) 168 (10): 5207–5212.

Abstract

View articletitled, Critical Role of Signaling Through IL-1 Receptor for Development of Arthritis and Sepsis During Staphylococcus aureus Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Complement C2 Receptor Inhibitor Trispanning and the β-Chain of C4 Share a Binding Site for Complement C2 ¹

Jameel M. Inal; Jürg A. Schifferli

J Immunol (2002) 168 (10): 5213–5221.

Abstract

View articletitled, Complement C2 Receptor Inhibitor Trispanning and the β-Chain of C4 Share a Binding Site for Complement C2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Human C1qRp Is Identical with CD93 and the mNI-11 Antigen But Does Not Bind C1q ¹

Eamon P. McGreal; Nobunao Ikewaki; Hiroyasu Akatsu; B. Paul Morgan; Philippe Gasque

J Immunol (2002) 168 (10): 5222–5232.

Abstract

View articletitled, Human C1qRp Is Identical with CD93 and the mNI-11 Antigen But Does Not Bind C1q<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4 ¹

Geoffrey B. Johnson; Gregory J. Brunn; Yuzo Kodaira; Jeffrey L. Platt

J Immunol (2002) 168 (10): 5233–5239.

Abstract

View articletitled, Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Two msbB Genes Encoding Maximal Acylation of Lipid A Are Required for Invasive Shigella flexneri to Mediate Inflammatory Rupture and Destruction of the Intestinal Epithelium ¹

Hélène d’Hauteville; Shahid Khan; Duncan J. Maskell; Anders Kussak; Andrej Weintraub; John Mathison; Richard J. Ulevitch; Nicole Wuscher; Claude Parsot; Philippe J. Sansonetti

J Immunol (2002) 168 (10): 5240–5251.

Abstract

View articletitled, Two msbB Genes Encoding Maximal Acylation of Lipid A Are Required for Invasive Shigella flexneri to Mediate Inflammatory Rupture and Destruction of the Intestinal Epithelium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulation of Toll-Like Receptor 4 Expression in the Lung Following Hemorrhagic Shock and Lipopolysaccharide ¹

Jie Fan; Andras Kapus; Philip A. Marsden; Yue Hua Li; George Oreopoulos; John C. Marshall; Stefan Frantz; Ralph A. Kelly; Ruslan Medzhitov; Ori D. Rotstein

J Immunol (2002) 168 (10): 5252–5259.

Abstract

View articletitled, Regulation of Toll-Like Receptor 4 Expression in the Lung Following Hemorrhagic Shock and Lipopolysaccharide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lipoxin A₄ Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis ¹

Andrew T. Gewirtz; Lauren S. Collier-Hyams; Andrew N. Young; Torsten Kucharzik; William J. Guilford; John F. Parkinson; Ifor R. Williams; Andrew S. Neish; James L. Madara

J Immunol (2002) 168 (10): 5260–5267.

Abstract

View articletitled, Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Chemokine Stromal Cell-Derived Factor-1α Modulates α₄β₇ Integrin-Mediated Lymphocyte Adhesion to Mucosal Addressin Cell Adhesion Molecule-1 and Fibronectin ¹

Natalia Wright; Andrés Hidalgo; José Miguel Rodríguez-Frade; Silvia F. Soriano; Mario Mellado; Marisa Parmo-Cabañas; Michael J. Briskin; Joaquin Teixidó

J Immunol (2002) 168 (10): 5268–5277.

Abstract

View articletitled, The Chemokine Stromal Cell-Derived Factor-1α Modulates α4β7 Integrin-Mediated Lymphocyte Adhesion to Mucosal Addressin Cell Adhesion Molecule-1 and Fibronectin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ-Inducible Protein 10 (CXCL10) Contributes to Airway Hyperreactivity and Airway Inflammation in a Mouse Model of Asthma ¹

Benjamin D. Medoff; Alain Sauty; Andrew M. Tager; James A. Maclean; R. Neal Smith; Anuja Mathew; Jennifer H. Dufour; Andrew D. Luster

J Immunol (2002) 168 (10): 5278–5286.

Abstract

View articletitled, IFN-γ-Inducible Protein 10 (CXCL10) Contributes to Airway Hyperreactivity and Airway Inflammation in a Mouse Model of Asthma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Localized Exocytosis of Primary (Lysosomal) Granules During Phagocytosis: Role of Ca²⁺-Dependent Tyrosine Phosphorylation and Microtubules ¹

Hans Tapper; Wendy Furuya; Sergio Grinstein

J Immunol (2002) 168 (10): 5287–5296.

Abstract

View articletitled, Localized Exocytosis of Primary (Lysosomal) Granules During Phagocytosis: Role of Ca2+-Dependent Tyrosine Phosphorylation and Microtubules<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mast Cell-Derived TNF-α Primes Sensory Nerve Endings in a Pulmonary Hypersensitivity Reaction

Anneke H. van Houwelingen; Mirjam Kool; Saskia C. A. de Jager; Frank A. M. Redegeld; Dicky van Heuven-Nolsen; Aletta D. Kraneveld; Frans P. Nijkamp

J Immunol (2002) 168 (10): 5297–5302.

Abstract

View articletitled, Mast Cell-Derived TNF-α Primes Sensory Nerve Endings in a Pulmonary Hypersensitivity Reaction

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Inhibition of Mitogen-Activated Protein Kinase Signaling by Chloroquine ¹

Stephen M. Weber; Jian-Min Chen; Stuart M. Levitz

J Immunol (2002) 168 (10): 5303–5309.

Abstract

View articletitled, Inhibition of Mitogen-Activated Protein Kinase Signaling by Chloroquine<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inflammatory Microcrystals Alter the Functional Phenotype of Human Osteoblast-Like Cells In Vitro: Synergism with IL-1 to Overexpress Cyclooxygenase-2 ¹

Line Bouchard; Rinaldo de Médicis; André Lussier; Paul H. Naccache; Patrice E. Poubelle

J Immunol (2002) 168 (10): 5310–5317.

Abstract

View articletitled, Inflammatory Microcrystals Alter the Functional Phenotype of Human Osteoblast-Like Cells In Vitro: Synergism with IL-1 to Overexpress Cyclooxygenase-2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Proinflammatory Role for the Cyclopentenone Prostaglandins at Low Micromolar Concentrations: Oxidative Stress-Induced Extracellular Signal-Regulated Kinase Activation Without NF-κB Inhibition ¹

Fabrice Bureau; Christophe Desmet; Dorothée Mélotte; Fabrice Jaspar; Cédric Volanti; Alain Vanderplasschen; Paul-Pierre Pastoret; Jacques Piette; Pierre Lekeux

J Immunol (2002) 168 (10): 5318–5325.

Abstract

View articletitled, A Proinflammatory Role for the Cyclopentenone Prostaglandins at Low Micromolar Concentrations: Oxidative Stress-Induced Extracellular Signal-Regulated Kinase Activation Without NF-κB Inhibition<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Immune Responses to Small Nuclear Ribonucleoproteins: Antigen-Dependent Distinct B Cell Epitope Spreading Patterns in Mice Immunized with Recombinant Polypeptides of Small Nuclear Ribonucleoproteins ¹

Umesh S. Deshmukh; Carol C. Kannapell; Shu Man Fu

J Immunol (2002) 168 (10): 5326–5332.

Abstract

View articletitled, Immune Responses to Small Nuclear Ribonucleoproteins: Antigen-Dependent Distinct B Cell Epitope Spreading Patterns in Mice Immunized with Recombinant Polypeptides of Small Nuclear Ribonucleoproteins<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Anatomic Localization of Immature and Mature Dendritic Cells in an Ectopic Lymphoid Organ: Correlation with Selective Chemokine Expression in Rheumatoid Synovium

Guillaume Page; Serge Lebecque; Pierre Miossec

J Immunol (2002) 168 (10): 5333–5341.

Abstract

View articletitled, Anatomic Localization of Immature and Mature Dendritic Cells in an Ectopic Lymphoid Organ: Correlation with Selective Chemokine Expression in Rheumatoid Synovium

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p38 Mitogen-Activated Protein Kinase Is Activated and Linked to TNF-α Signaling in Inflammatory Bowel Disease ¹

Georg H. Waetzig; Dirk Seegert; Philip Rosenstiel; Susanna Nikolaus; Stefan Schreiber

J Immunol (2002) 168 (10): 5342–5351.

Abstract

View articletitled, p38 Mitogen-Activated Protein Kinase Is Activated and Linked to TNF-α Signaling in Inflammatory Bowel Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Intact Active Bone Transplantation Synergizes with Anti-CD40 Ligand Therapy to Induce B Cell Tolerance ¹

Dengping Yin; LianLi Ma; Anncy Varghese; JiKun Shen; Anita S.-F. Chong

J Immunol (2002) 168 (10): 5352–5358.

Abstract

View articletitled, Intact Active Bone Transplantation Synergizes with Anti-CD40 Ligand Therapy to Induce B Cell Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Characterization of Drug-Specific T Cells in Phenobarbital- Induced Eruption

Hideo Hashizume; Masahiro Takigawa; Yoshiki Tokura

J Immunol (2002) 168 (10): 5359–5368.

Abstract

View articletitled, Characterization of Drug-Specific T Cells in Phenobarbital- Induced Eruption

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Molecular Mechanisms for Gender Differences in Susceptibility to T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice ¹

Min Bao; Yang Yang; Hee-Sook Jun; Ji-Won Yoon

J Immunol (2002) 168 (10): 5369–5375.

Abstract

View articletitled, Molecular Mechanisms for Gender Differences in Susceptibility to T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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ERRATA

Toll-Like Receptor 4-MD-2 Complex Mediates the Signal Transduction Induced by Flavolipin, an Amino Acid-Containing Lipid Unique to Flavobacterium meningosepticum

Kazunori Gomi; Kiyoshi Kawasaki; Yohko Kawai; Masao Shiozaki; Masahiro Nishijima

J Immunol (2002) 168 (10): 5376.

View articletitled, Toll-Like Receptor 4-MD-2 Complex Mediates the Signal Transduction Induced by Flavolipin, an Amino Acid-Containing Lipid Unique to Flavobacterium meningosepticum

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Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis

Larisa Y. Poluektova; David H. Munn; Yuri Persidsky; Howard E. Gendelman

J Immunol (2002) 168 (10): 5376.

View articletitled, Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

ERRATA

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