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CUTTING EDGE

Cutting Edge: IFN-Producing Cells Respond to CXCR3 Ligands in the Presence of CXCL12 and Secrete Inflammatory Chemokines upon Activation ¹

Anne Krug; Ravindra Uppaluri; Fabio Facchetti; Brigitte G. Dorner; Kathleen C. F. Sheehan; Robert D. Schreiber; Marina Cella; Marco Colonna

J Immunol (2002) 169 (11): 6079–6083.

Abstract

View articletitled, Cutting Edge: IFN-Producing Cells Respond to CXCR3 Ligands in the Presence of CXCL12 and Secrete Inflammatory Chemokines upon Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

The Fate of Effector T Cells In Vivo Is Determined During Activation and Differs for CD4⁺ and CD8⁺ Cells ¹

Ulrike Bode; Andrea Sahle; Gisela Sparmann; Frauke Weidner; Jürgen Westermann

J Immunol (2002) 169 (11): 6085–6091.

Abstract

View articletitled, The Fate of Effector T Cells In Vivo Is Determined During Activation and Differs for CD4+ and CD8+ Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Live-Cell Dynamics and the Role of Costimulation in Immunological Synapse Formation ¹

Scott A. Wetzel; Timothy W. McKeithan; David C. Parker

J Immunol (2002) 169 (11): 6092–6101.

Abstract

View articletitled, Live-Cell Dynamics and the Role of Costimulation in Immunological Synapse Formation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Supplementary data

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NK Cell CD94/NKG2A Inhibitory Receptors Are Internalized and Recycle Independently of Inhibitory Signaling Processes

Francisco Borrego; Juraj Kabat; Tolib B. Sanni; John E. Coligan

J Immunol (2002) 169 (11): 6102–6111.

Abstract

View articletitled, NK Cell CD94/NKG2A Inhibitory Receptors Are Internalized and Recycle Independently of Inhibitory Signaling Processes

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Bacterial-Reactive T Regulatory Cells Inhibit Pathogenic Immune Responses to the Enteric Flora ¹

Yingzi Cong; Casey T. Weaver; Audrey Lazenby; Charles O. Elson

J Immunol (2002) 169 (11): 6112–6119.

Abstract

View articletitled, Bacterial-Reactive T Regulatory Cells Inhibit Pathogenic Immune Responses to the Enteric Flora<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Determinants of Autoantibody Induction by Conjugated Papillomavirus Virus-Like Particles

Bryce Chackerian; Petra Lenz; Douglas R. Lowy; John T. Schiller

J Immunol (2002) 169 (11): 6120–6126.

Abstract

View articletitled, Determinants of Autoantibody Induction by Conjugated Papillomavirus Virus-Like Particles

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Age-Associated Augmentation of the Synthetic Ligand- Mediated Function of Mouse NK1.1 Ag⁺ T Cells: Their Cytokine Production and Hepatotoxicity In Vivo and In Vitro

Takuo Inui; Ryusuke Nakagawa; Shuri Ohkura; Yoshiko Habu; Yuji Koike; Kazuhiro Motoki; Noritsugu Kuranaga; Masashi Fukasawa; Nariyoshi Shinomiya; Shuhji Seki

J Immunol (2002) 169 (11): 6127–6132.

Abstract

View articletitled, Age-Associated Augmentation of the Synthetic Ligand- Mediated Function of Mouse NK1.1 Ag+ T Cells: Their Cytokine Production and Hepatotoxicity In Vivo and In Vitro

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Multilineage Engraftment with Minimal Graft-Versus-Host Disease Following In Utero Transplantation of S-59 Psoralen/Ultraviolet A Light-Treated, Sensitized T Cells and Adult T Cell-Depleted Bone Marrow in Fetal Mice ¹

Swati Bhattacharyya; Anjulika Chawla; Kristofer Smith; Yungui Zhou; Sohel Talib; Brian Wardwell; Morton J. Cowan

J Immunol (2002) 169 (11): 6133–6140.

Abstract

View articletitled, Multilineage Engraftment with Minimal Graft-Versus-Host Disease Following In Utero Transplantation of S-59 Psoralen/Ultraviolet A Light-Treated, Sensitized T Cells and Adult T Cell-Depleted Bone Marrow in Fetal Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Different Efficiency of Heat Shock Proteins (HSP) to Activate Human Monocytes and Dendritic Cells: Superiority of HSP60 ¹

Karen Bethke; Frank Staib; Martin Distler; Ute Schmitt; Helmut Jonuleit; Alexander H. Enk; Peter R. Galle; Michael Heike

J Immunol (2002) 169 (11): 6141–6148.

Abstract

View articletitled, Different Efficiency of Heat Shock Proteins (HSP) to Activate Human Monocytes and Dendritic Cells: Superiority of HSP60<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Zwitterionic Polysaccharides Stimulate T Cells by MHC Class II-Dependent Interactions ¹

Wiltrud M. Kalka-Moll; Arthur O. Tzianabos; Paula W. Bryant; Marcus Niemeyer; Hidde L. Ploegh; Dennis L. Kasper

J Immunol (2002) 169 (11): 6149–6153.

Abstract

View articletitled, Zwitterionic Polysaccharides Stimulate T Cells by MHC Class II-Dependent Interactions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mouse Vascular Endothelium Activates CD8⁺ T Lymphocytes in a B7-Dependent Fashion ¹

Daniel Kreisel; Alexander S. Krupnick; Keki R. Balsara; Markus Riha; Andrew E. Gelman; Sicco H. Popma; Wilson Y. Szeto; Laurence A. Turka; Bruce R. Rosengard

J Immunol (2002) 169 (11): 6154–6161.

Abstract

View articletitled, Mouse Vascular Endothelium Activates CD8+ T Lymphocytes in a B7-Dependent Fashion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Acquisition of CD80 by Human T Cells at Early Stages of Activation: Functional Involvement of CD80 Acquisition in T Cell to T Cell Interaction

Zohreh Tatari-Calderone; Roshanak Tolouei Semnani; Thomas B. Nutman; Jeffrey Schlom; Helen Sabzevari

J Immunol (2002) 169 (11): 6162–6169.

Abstract

View articletitled, Acquisition of CD80 by Human T Cells at Early Stages of Activation: Functional Involvement of CD80 Acquisition in T Cell to T Cell Interaction

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Kinetics of Gene Induction After FcεRI Ligation of Atopic Monocytes Identified by Suppression Subtractive Hybridization ¹

Dagmar von Bubnoff; Heike Matz; Jean-Pierre Cazenave; Daniel Hanau; Thomas Bieber; Henri de la Salle

J Immunol (2002) 169 (11): 6170–6177.

Abstract

View articletitled, Kinetics of Gene Induction After FcεRI Ligation of Atopic Monocytes Identified by Suppression Subtractive Hybridization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Clonal Anergy Is Maintained Independently of T Cell Proliferation ¹

Sara Colombetti; Fabio Benigni; Veronica Basso; Anna Mondino

J Immunol (2002) 169 (11): 6178–6186.

Abstract

View articletitled, Clonal Anergy Is Maintained Independently of T Cell Proliferation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Autocrine IL-15 Mediates Intestinal Epithelial Cell Death Via the Activation of Neighboring Intraepithelial NK Cells ¹

Naotoshi Kinoshita; Takachika Hiroi; Noriyuki Ohta; Satoshi Fukuyama; Eun Jeong Park; Hiroshi Kiyono

J Immunol (2002) 169 (11): 6187–6192.

Abstract

View articletitled, Autocrine IL-15 Mediates Intestinal Epithelial Cell Death Via the Activation of Neighboring Intraepithelial NK Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Bone Marrow B Cell Apoptosis During In Vivo Influenza Virus Infection Requires TNF-α and Lymphotoxin-α ¹

Lisa M. Sedger; Sam Hou; Sarah R. Osvath; Moira B. Glaccum; Jacques J. Peschon; Nico van Rooijen; Lisa Hyland

J Immunol (2002) 169 (11): 6193–6201.

Abstract

View articletitled, Bone Marrow B Cell Apoptosis During In Vivo Influenza Virus Infection Requires TNF-α and Lymphotoxin-α<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CTLA-4 Differentially Regulates T Cell Responses to Endogenous Tissue Protein Versus Exogenous Immunogen ¹

Lucy S. K. Walker; Lara J. Ausubel; Anna Chodos; Nyree Bekarian; Abul K. Abbas

J Immunol (2002) 169 (11): 6202–6209.

Abstract

View articletitled, CTLA-4 Differentially Regulates T Cell Responses to Endogenous Tissue Protein Versus Exogenous Immunogen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of Human CD4⁺CD25^+high Regulatory T Cell Function ¹

Clare Baecher-Allan; Vissia Viglietta; David A. Hafler

J Immunol (2002) 169 (11): 6210–6217.

Abstract

View articletitled, Inhibition of Human CD4+CD25+high Regulatory T Cell Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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T Cell Receptor Ligation Triggers Novel Nonapoptotic Cell Death Pathways That Are Fas-Independent or Fas-Dependent ³

Wendy F. Davidson; Christian Haudenschild; Jaeyul Kwon; Mark S. Williams

J Immunol (2002) 169 (11): 6218–6230.

Abstract

View articletitled, T Cell Receptor Ligation Triggers Novel Nonapoptotic Cell Death Pathways That Are Fas-Independent or Fas-Dependent<a href="javascript:;" reveal-id="FN3" data-open="FN3" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">3</a>

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Cyclic Adenosine 5′-Monophosphate and Calcium Induce CD152 (CTLA-4) Up-Regulation in Resting CD4⁺ T Lymphocytes

Silvia Vendetti; Antonella Riccomi; Alessandra Sacchi; Lucia Gatta; Claudio Pioli; Maria Teresa De Magistris

J Immunol (2002) 169 (11): 6231–6235.

Abstract

View articletitled, Cyclic Adenosine 5′-Monophosphate and Calcium Induce CD152 (CTLA-4) Up-Regulation in Resting CD4+ T Lymphocytes

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

NF-κB Regulates the Expression of the Human Complement Receptor 2 Gene ¹

Mate Tolnay; Lyudmila A. Vereshchagina; George C. Tsokos

J Immunol (2002) 169 (11): 6236–6243.

Abstract

View articletitled, NF-κB Regulates the Expression of the Human Complement Receptor 2 Gene<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Primary Structure and Complementarity-Determining Region (CDR) 3 Spectratyping of Rainbow Trout TCRβ Transcripts Identify Ten Vβ Families with Vβ6 Displaying Unusual CDR2 and Differently Spliced Forms ¹

Pierre Boudinot; Samira Boubekeur; Abdenour Benmansour

J Immunol (2002) 169 (11): 6244–6252.

Abstract

View articletitled, Primary Structure and Complementarity-Determining Region (CDR) 3 Spectratyping of Rainbow Trout TCRβ Transcripts Identify Ten Vβ Families with Vβ6 Displaying Unusual CDR2 and Differently Spliced Forms<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dominant TCR-α Requirements for a Self Antigen Recognition in Humans

Stefania Mantovani; Belinda Palermo; Silvia Garbelli; Rita Campanelli; Gioacchino Robustelli della Cuna; Roberto Gennari; Federica Benvenuto; Erica Lantelme; Claudia Giachino

J Immunol (2002) 169 (11): 6253–6260.

Abstract

View articletitled, Dominant TCR-α Requirements for a Self Antigen Recognition in Humans

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CD4 Dimers Constitute the Functional Component Required for T Cell Activation ¹

Maria-Cristina Moldovan; Abdelkader Yachou; Karine Lévesque; Hao Wu; Wayne A. Hendrickson; Eric A. Cohen; Rafick-Pierre Sékaly

J Immunol (2002) 169 (11): 6261–6268.

Abstract

View articletitled, CD4 Dimers Constitute the Functional Component Required for T Cell Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulation of Constitutive TCR Internalization by the ζ-Chain

Ugo D’Oro; Ivana Munitic; George Chacko; Tatiana Karpova; James McNally; Jonathan D. Ashwell

J Immunol (2002) 169 (11): 6269–6278.

Abstract

View articletitled, Regulation of Constitutive TCR Internalization by the ζ-Chain

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Making Sense of the Diverse Ligand Recognition by NKG2D ¹

Sergei Radaev; Michael Kattah; Zhongcheng Zou; Marco Colonna; Peter D. Sun

J Immunol (2002) 169 (11): 6279–6285.

Abstract

View articletitled, Making Sense of the Diverse Ligand Recognition by NKG2D<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Mycobacterium avium Infection and Modulation of Human Macrophage Gene Expression

Teresa Greenwell-Wild; Nancy Vázquez; Davis Sim; Marco Schito; Delphi Chatterjee; Jan M. Orenstein; Sharon M. Wahl

J Immunol (2002) 169 (11): 6286–6297.

Abstract

View articletitled, Mycobacterium avium Infection and Modulation of Human Macrophage Gene Expression

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B7/CD28-Dependent CD4⁺CD25⁺ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans¹

Claudia Montagnoli; Angela Bacci; Silvia Bozza; Roberta Gaziano; Paolo Mosci; Arlene H. Sharpe; Luigina Romani

J Immunol (2002) 169 (11): 6298–6308.

Abstract

View articletitled, B7/CD28-Dependent CD4+CD25+ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ-Induced Apoptosis and Microbicidal Activity in Monocytes Harboring the Intracellular Bacterium Coxiella burnetii Require Membrane TNF and Homotypic Cell Adherence ¹

Jérôme Dellacasagrande; Eric Ghigo; Didier Raoult; Christian Capo; Jean-Louis Mege

J Immunol (2002) 169 (11): 6309–6315.

Abstract

View articletitled, IFN-γ-Induced Apoptosis and Microbicidal Activity in Monocytes Harboring the Intracellular Bacterium Coxiella burnetii Require Membrane TNF and Homotypic Cell Adherence<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evolution of the Cutaneous Immune Response to Experimental Haemophilus ducreyi Infection and Its Relevance to HIV-1 Acquisition ¹ ^²

Tricia L. Humphreys; Carol T. Schnizlein-Bick; Barry P. Katz; Lee Ann Baldridge; Antoinette F. Hood; Robert A. Hromas; Stanley M. Spinola

J Immunol (2002) 169 (11): 6316–6323.

Abstract

View articletitled, Evolution of the Cutaneous Immune Response to Experimental Haemophilus ducreyi Infection and Its Relevance to HIV-1 Acquisition<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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GM-CSF Transgene-Based Adjuvant Allows the Establishment of Protective Mucosal Immunity Following Vaccination with Inactivated Chlamydia trachomatis¹

Hang Lu; Zhou Xing; Robert C. Brunham

J Immunol (2002) 169 (11): 6324–6331.

Abstract

View articletitled, GM-CSF Transgene-Based Adjuvant Allows the Establishment of Protective Mucosal Immunity Following Vaccination with Inactivated Chlamydia trachomatis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Endocytic Internalization of Adenovirus, Nonspecific Phagocytosis, and Cytoskeletal Organization Are Coordinately Regulated in Alveolar Macrophages by GM-CSF and PU.1 ¹

Pierre-Yves Berclaz; Zsuzsanna Zsengellér; Yoko Shibata; Kazuhisa Otake; Steven Strasbaugh; Jeffrey A. Whitsett; Bruce C. Trapnell

J Immunol (2002) 169 (11): 6332–6342.

Abstract

View articletitled, Endocytic Internalization of Adenovirus, Nonspecific Phagocytosis, and Cytoskeletal Organization Are Coordinately Regulated in Alveolar Macrophages by GM-CSF and PU.1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vivo IL-10 Production Reactivates Chronic Pulmonary Tuberculosis in C57BL/6 Mice ¹

Joanne Turner; Mercedes Gonzalez-Juarrero; Debi L. Ellis; Randy J. Basaraba; Andre Kipnis; Ian M. Orme; Andrea M. Cooper

J Immunol (2002) 169 (11): 6343–6351.

Abstract

View articletitled, In Vivo IL-10 Production Reactivates Chronic Pulmonary Tuberculosis in C57BL/6 Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Novel Interaction of Outer Membrane Protein A with C4b Binding Protein Mediates Serum Resistance of Escherichia coli K1 ¹

Nemani V. Prasadarao; Anna M. Blom; Bruno O. Villoutreix; Linette C. Linsangan

J Immunol (2002) 169 (11): 6352–6360.

Abstract

View articletitled, A Novel Interaction of Outer Membrane Protein A with C4b Binding Protein Mediates Serum Resistance of Escherichia coli K1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HIV-1 Protein Vpr Suppresses IL-12 Production from Human Monocytes by Enhancing Glucocorticoid Action: Potential Implications of Vpr Coactivator Activity for the Innate and Cellular Immunity Deficits Observed in HIV-1 Infection

Marco Mirani; Ilia Elenkov; Simona Volpi; Naoki Hiroi; George P. Chrousos; Tomoshige Kino

J Immunol (2002) 169 (11): 6361–6368.

Abstract

View articletitled, HIV-1 Protein Vpr Suppresses IL-12 Production from Human Monocytes by Enhancing Glucocorticoid Action: Potential Implications of Vpr Coactivator Activity for the Innate and Cellular Immunity Deficits Observed in HIV-1 Infection

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On the Pathogenic Role of Brain-Sequestered αβ CD8⁺ T Cells in Experimental Cerebral Malaria ¹

Elodie Belnoue; Michèle Kayibanda; Ana M. Vigario; Jean-Christophe Deschemin; Nico van Rooijen; Mireille Viguier; Georges Snounou; Laurent Rénia

J Immunol (2002) 169 (11): 6369–6375.

Abstract

View articletitled, On the Pathogenic Role of Brain-Sequestered αβ CD8+ T Cells in Experimental Cerebral Malaria<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Presence of HIV-1 Gag-Specific IFN-γ⁺IL-2⁺ and CD28⁺IL-2⁺ CD4 T Cell Responses Is Associated with Nonprogression in HIV-1 Infection ¹

Mark J. Boaz; Anele Waters; Shahed Murad; Philippa J. Easterbrook; Annapurna Vyakarnam

J Immunol (2002) 169 (11): 6376–6385.

Abstract

View articletitled, Presence of HIV-1 Gag-Specific IFN-γ+IL-2+ and CD28+IL-2+ CD4 T Cell Responses Is Associated with Nonprogression in HIV-1 Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

CD4⁺ TCR Repertoire Heterogeneity in Schistosoma mansoni-Induced Granulomas ¹

Laura H. Hogan; Margaret Wang; M. Suresh; Dominic O. Co; Joel V. Weinstock; Matyas Sandor

J Immunol (2002) 169 (11): 6386–6393.

Abstract

View articletitled, CD4+ TCR Repertoire Heterogeneity in Schistosoma mansoni-Induced Granulomas<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Sphingosine Kinase: A Point of Convergence in the Action of Diverse Neutrophil Priming Agents ¹

Alison C. MacKinnon; Avril Buckley; Edwin R. Chilvers; Adriano G. Rossi; Christopher Haslett; Tariq Sethi

J Immunol (2002) 169 (11): 6394–6400.

Abstract

View articletitled, Sphingosine Kinase: A Point of Convergence in the Action of Diverse Neutrophil Priming Agents<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Caspase-1-Deficient Mice Have Delayed Neutrophil Apoptosis and a Prolonged Inflammatory Response to Lipopolysaccharide-Induced Acute Lung Injury ¹

Sarah J. Rowe; Lucy Allen; Victoria C. Ridger; Paul G. Hellewell; Moira K. B. Whyte

J Immunol (2002) 169 (11): 6401–6407.

Abstract

View articletitled, Caspase-1-Deficient Mice Have Delayed Neutrophil Apoptosis and a Prolonged Inflammatory Response to Lipopolysaccharide-Induced Acute Lung Injury<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Restraint of Proinflammatory Cytokine Biosynthesis by Mitogen-Activated Protein Kinase Phosphatase-1 in Lipopolysaccharide-Stimulated Macrophages

Peili Chen; Ji Li; Janice Barnes; Gertrude C. Kokkonen; John C. Lee; Yusen Liu

J Immunol (2002) 169 (11): 6408–6416.

Abstract

View articletitled, Restraint of Proinflammatory Cytokine Biosynthesis by Mitogen-Activated Protein Kinase Phosphatase-1 in Lipopolysaccharide-Stimulated Macrophages

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Function of the Lectin Domain of Mac-1/Complement Receptor Type 3 (CD11b/CD18) in Regulating Neutrophil Adhesion ¹

Yu Xia; Gita Borland; Jibiao Huang; Ikuko F. Mizukami; Howard R. Petty; Robert F. Todd, III; Gordon D. Ross

J Immunol (2002) 169 (11): 6417–6426.

Abstract

View articletitled, Function of the Lectin Domain of Mac-1/Complement Receptor Type 3 (CD11b/CD18) in Regulating Neutrophil Adhesion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Macrophage-Colony-Stimulating Factor-Induced Activation of Extracellular-Regulated Kinase Involves Phosphatidylinositol 3-Kinase and Reactive Oxygen Species in Human Monocytes ¹

Nitin Y. Bhatt; Todd W. Kelley; Valery V. Khramtsov; Yijie Wang; Gregory K. Lam; Thomas L. Clanton; Clay B. Marsh

J Immunol (2002) 169 (11): 6427–6434.

Abstract

View articletitled, Macrophage-Colony-Stimulating Factor-Induced Activation of Extracellular-Regulated Kinase Involves Phosphatidylinositol 3-Kinase and Reactive Oxygen Species in Human Monocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Potent and Selective Nonpeptide Antagonist of CXCR2 Inhibits Acute and Chronic Models of Arthritis in the Rabbit ¹

Patricia L. Podolin; Brian J. Bolognese; James J. Foley; Dulcie B. Schmidt; Peter T. Buckley; Katherine L. Widdowson; Qi Jin; John R. White; Judithann M. Lee; Richard B. Goodman; Tonja R. Hagen; Osamu Kajikawa; Lisa A. Marshall; Douglas W. P. Hay; Henry M. Sarau

J Immunol (2002) 169 (11): 6435–6444.

Abstract

View articletitled, A Potent and Selective Nonpeptide Antagonist of CXCR2 Inhibits Acute and Chronic Models of Arthritis in the Rabbit<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Expression of the C-X-C Chemokine Receptor CXCR4 by Human Bronchial Epithelial Cells: Regulation by Proinflammatory Mediators ¹ ^²

Jane Eddleston; Sandra C. Christiansen; Bruce L. Zuraw

J Immunol (2002) 169 (11): 6445–6451.

Abstract

View articletitled, Functional Expression of the C-X-C Chemokine Receptor CXCR4 by Human Bronchial Epithelial Cells: Regulation by Proinflammatory Mediators<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: I. Loss of Membrane IL-5 Receptor α on Airway Eosinophils and Increased Soluble IL-5 Receptor α in the Airway After Allergen Challenge ¹

Lin Ying Liu; Julie B. Sedgwick; Mary Ellen Bates; Rose F. Vrtis; James E. Gern; Hirohita Kita; Nizar N. Jarjour; William W. Busse; Elizabeth A. B. Kelly

J Immunol (2002) 169 (11): 6452–6458.

Abstract

View articletitled, Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: I. Loss of Membrane IL-5 Receptor α on Airway Eosinophils and Increased Soluble IL-5 Receptor α in the Airway After Allergen Challenge<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: II. IL-5 Down-Modulates Its Receptor Via a Proteinase-Mediated Process ¹

Lin Ying Liu; Julie B. Sedgwick; Mary Ellen Bates; Rose F. Vrtis; James E. Gern; Hirohita Kita; Nizar N. Jarjour; William W. Busse; Elizabeth A. B. Kelly

J Immunol (2002) 169 (11): 6459–6466.

Abstract

View articletitled, Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: II. IL-5 Down-Modulates Its Receptor Via a Proteinase-Mediated Process<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Resident Cell Chemokine Expression Serves as the Major Mechanism for Leukocyte Recruitment During Local Inflammation

Eva García-Ramallo; Teresa Marques; Neus Prats; Jordi Beleta; Steven L. Kunkel; Nuria Godessart

J Immunol (2002) 169 (11): 6467–6473.

Abstract

View articletitled, Resident Cell Chemokine Expression Serves as the Major Mechanism for Leukocyte Recruitment During Local Inflammation

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Proinflammatory Gene Induction by Platelet-Activating Factor Mediated Via Its Cognate Nuclear Receptor ¹

A. Marilise Marrache; Fernand Gobeil, Jr.; Sylvie G. Bernier; Jana Stankova; Marek Rola-Pleszczynski; Sanaa Choufani; Ghassan Bkaily; Annie Bourdeau; Martin G. Sirois; Alejandro Vazquez-Tello; Li Fan; Jean-Sébastien Joyal; Janos G. Filep; Daya R. Varma; Alfredo Ribeiro-da-Silva; Sylvain Chemtob

J Immunol (2002) 169 (11): 6474–6481.

Abstract

View articletitled, Proinflammatory Gene Induction by Platelet-Activating Factor Mediated Via Its Cognate Nuclear Receptor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of IL-13 in Established Allergic Airway Disease ¹

Christian Taube; Catherine Duez; Zhi-Hua Cui; Katsuyuki Takeda; Yeong-Ho Rha; Jung-Won Park; Annette Balhorn; Debra D. Donaldson; Azzeddine Dakhama; Erwin W. Gelfand

J Immunol (2002) 169 (11): 6482–6489.

Abstract

View articletitled, The Role of IL-13 in Established Allergic Airway Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Piceatannol Inhibits TNF-Induced NF-κB Activation and NF-κB-Mediated Gene Expression Through Suppression of IκBα Kinase and p65 Phosphorylation ¹

Kazuhiro Ashikawa; Sekhar Majumdar; Sanjeev Banerjee; Alok C. Bharti; Shishir Shishodia; Bharat B. Aggarwal

J Immunol (2002) 169 (11): 6490–6497.

Abstract

View articletitled, Piceatannol Inhibits TNF-Induced NF-κB Activation and NF-κB-Mediated Gene Expression Through Suppression of IκBα Kinase and p65 Phosphorylation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lipopolysaccharide-Induced Leukocyte Lipid Body Formation In Vivo: Innate Immunity Elicited Intracellular Loci Involved in Eicosanoid Metabolism ¹

Patrícia Pacheco; Fernando A. Bozza; Rachel N. Gomes; Marcelo Bozza; Peter F. Weller; Hugo C. Castro-Faria-Neto; Patrícia T. Bozza

J Immunol (2002) 169 (11): 6498–6506.

Abstract

View articletitled, Lipopolysaccharide-Induced Leukocyte Lipid Body Formation In Vivo: Innate Immunity Elicited Intracellular Loci Involved in Eicosanoid Metabolism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

A Novel Class II-Binding Motif Selects Peptides That Mediate Organ-Specific Autoimmune Disease in SWXJ, SJL/J, and SWR/J Mice ¹

Daniel Jane-wit; Min Yu; Andrea E. Edling; Seiko Kataoka; Justin M. Johnson; Linda B. Stull; Christine S. Moravec; Vincent K. Tuohy

J Immunol (2002) 169 (11): 6507–6514.

Abstract

View articletitled, A Novel Class II-Binding Motif Selects Peptides That Mediate Organ-Specific Autoimmune Disease in SWXJ, SJL/J, and SWR/J Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Imbalance in the Expression of CXC Chemokines Correlates with Bronchoalveolar Lavage Fluid Angiogenic Activity and Procollagen Levels in Acute Respiratory Distress Syndrome ¹

Michael P. Keane; Seamas C. Donnelly; John A. Belperio; Richard B. Goodman; Maria Dy; Marie D. Burdick; Michael C. Fishbein; Robert M. Strieter

J Immunol (2002) 169 (11): 6515–6521.

Abstract

View articletitled, Imbalance in the Expression of CXC Chemokines Correlates with Bronchoalveolar Lavage Fluid Angiogenic Activity and Procollagen Levels in Acute Respiratory Distress Syndrome<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Production of Type I IFN Sensitizes Macrophages to Cell Death Induced by Listeria monocytogenes¹

Silvia Stockinger; Tilo Materna; Dagmar Stoiber; Lourdes Bayr; Ralf Steinborn; Thomas Kolbe; Hermann Unger; Trinad Chakraborty; David E. Levy; Mathias Müller; Thomas Decker

J Immunol (2002) 169 (11): 6522–6529.

Abstract

View articletitled, Production of Type I IFN Sensitizes Macrophages to Cell Death Induced by Listeria monocytogenes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of TGFβ1 by Anti-TGFβ1 Antibody or Lisinopril Reduces Thyroid Fibrosis in Granulomatous Experimental Autoimmune Thyroiditis ¹

Kemin Chen; Yongzhong Wei; Gordon C. Sharp; Helen Braley-Mullen

J Immunol (2002) 169 (11): 6530–6538.

Abstract

View articletitled, Inhibition of TGFβ1 by Anti-TGFβ1 Antibody or Lisinopril Reduces Thyroid Fibrosis in Granulomatous Experimental Autoimmune Thyroiditis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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First-Generation Adenovirus Vectors Shorten Survival Time in a Murine Model of Sepsis ¹

Kevin Doerschug; Salih Sanlioglu; Dawn M. Flaherty; Rebecca L. Wilson; Timur Yarovinsky; Martha M. Monick; John F. Engelhardt; Gary W. Hunninghake

J Immunol (2002) 169 (11): 6539–6545.

Abstract

View articletitled, First-Generation Adenovirus Vectors Shorten Survival Time in a Murine Model of Sepsis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Programmed Death-1 Targeting Can Promote Allograft Survival ¹

Engin Özkaynak; Liqing Wang; Andrew Goodearl; Kevin McDonald; Shixin Qin; Theresa O’Keefe; Thao Duong; Tammy Smith; Jose-Carlos Gutierrez-Ramos; James B. Rottman; Anthony J. Coyle; Wayne W. Hancock

J Immunol (2002) 169 (11): 6546–6553.

Abstract

View articletitled, Programmed Death-1 Targeting Can Promote Allograft Survival<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Prevention of Experimental Autoimmune Encephalomyelitis in Common Marmosets Using an Anti-IL-12p40 Monoclonal Antibody ¹

Herbert P. M. Brok; Marjan van Meurs; Erwin Blezer; Allen Schantz; David Peritt; George Treacy; Jon D. Laman; Jan Bauer; Bert A. ’t Hart

J Immunol (2002) 169 (11): 6554–6563.

Abstract

View articletitled, Prevention of Experimental Autoimmune Encephalomyelitis in Common Marmosets Using an Anti-IL-12p40 Monoclonal Antibody<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antigen-Based Immunotherapy Drives the Precocious Development of Autoimmunity ¹

Jide Tian; Angelica P. Olcott; Daniel L. Kaufman

J Immunol (2002) 169 (11): 6564–6569.

Abstract

View articletitled, Antigen-Based Immunotherapy Drives the Precocious Development of Autoimmunity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Split Tolerance in a Novel Transgenic Model of Autoimmune Myasthenia Gravis ¹

Sue Stacy; Bruce E. Gelb; Barbara A. Koop; Jolene J. Windle; Katherine A. Wall; Keith A. Krolick; Anthony J. Infante; Ellen Kraig

J Immunol (2002) 169 (11): 6570–6579.

Abstract

View articletitled, Split Tolerance in a Novel Transgenic Model of Autoimmune Myasthenia Gravis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Increased Nonobese Diabetic Th1:Th2 (IFN-γ:IL-4) Ratio Is CD4⁺ T Cell Intrinsic and Independent of APC Genetic Background ¹

Syuichi Koarada; Yuehong Wu; Grace Olshansky; William M. Ridgway

J Immunol (2002) 169 (11): 6580–6587.

Abstract

View articletitled, Increased Nonobese Diabetic Th1:Th2 (IFN-γ:IL-4) Ratio Is CD4+ T Cell Intrinsic and Independent of APC Genetic Background<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rapid Induction of Apoptosis in CD8⁺ HIV-1 Envelope-Specific Murine CTLs by Short Exposure to Antigenic Peptide ¹

Megumi Takahashi; Eiichi Osono; Yohko Nakagawa; Jian Wang; Jay A. Berzofsky; David H. Margulies; Hidemi Takahashi

J Immunol (2002) 169 (11): 6588–6593.

Abstract

View articletitled, Rapid Induction of Apoptosis in CD8+ HIV-1 Envelope-Specific Murine CTLs by Short Exposure to Antigenic Peptide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ongoing In Vivo Immunoglobulin Class Switch DNA Recombination in Chronic Lymphocytic Leukemia B Cells ¹

Andrea Cerutti; Hong Zan; Edmund C. Kim; Shefali Shah; Elaine J. Schattner; András Schaffer; Paolo Casali

J Immunol (2002) 169 (11): 6594–6603.

Abstract

View articletitled, Ongoing In Vivo Immunoglobulin Class Switch DNA Recombination in Chronic Lymphocytic Leukemia B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of FcγR Signaling in the K/B × N Serum Transfer Model of Arthritis ¹

Maripat Corr; Brian Crain

J Immunol (2002) 169 (11): 6604–6609.

Abstract

View articletitled, The Role of FcγR Signaling in the K/B × N Serum Transfer Model of Arthritis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rheumatoid Arthritis Synoviocyte Survival Is Dependent on Stat3 ¹

Anja Krause; Nicholas Scaletta; Jong-Dae Ji; Lionel B. Ivashkiv

J Immunol (2002) 169 (11): 6610–6616.

Abstract

View articletitled, Rheumatoid Arthritis Synoviocyte Survival Is Dependent on Stat3<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Natural Autoantibody Repertoire of Nonobese Diabetic Mice Is Highly Active ¹

James W. Thomas; Peggy L. Kendall; Holly G. Mitchell

J Immunol (2002) 169 (11): 6617–6624.

Abstract

View articletitled, The Natural Autoantibody Repertoire of Nonobese Diabetic Mice Is Highly Active<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential MHC Class II-Mediated Presentation of Rheumatoid Arthritis Autoantigens by Human Dendritic Cells and Macrophages ¹

Eleanor C. Tsark; Wei Wang; Yu-Chin Teng; Daniel Arkfeld; George R. Dodge; Susan Kovats

J Immunol (2002) 169 (11): 6625–6633.

Abstract

View articletitled, Differential MHC Class II-Mediated Presentation of Rheumatoid Arthritis Autoantigens by Human Dendritic Cells and Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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