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J Immunol (2003) 170 (10): 4879–4880.

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CUTTING EDGE

Cutting Edge: The NK Cell Receptor 2B4 Augments Antigen-Specific T Cell Cytotoxicity Through CD48 Ligation on Neighboring T Cells ¹

Kyung-Mi Lee; Sadhna Bhawan; Takashi Majima; Hairong Wei; Michael I. Nishimura; Hideo Yagita; Vinay Kumar

J Immunol (2003) 170 (10): 4881–4885.

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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment ¹

Atsunobu Takeda; Shinjiro Hamano; Atsushi Yamanaka; Toshikatsu Hanada; Tatsuro Ishibashi; Tak W. Mak; Akihiko Yoshimura; Hiroki Yoshida

J Immunol (2003) 170 (10): 4886–4890.

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Cutting Edge: Dependence of TCR Antagonism on Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Activity ¹

Neely E. Kilgore; Jenny D. Carter; Ulrike Lorenz; Brian D. Evavold

J Immunol (2003) 170 (10): 4891–4895.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Environmental Chemical-Induced Pro/Pre-B Cell Apoptosis: Analysis of c-Myc, p27^Kip1, and p21^WAF1 Reveals a Death Pathway Distinct from Clonal Deletion ¹

Heui-Young Ryu; Koren K. Mann; Jennifer J. Schlezinger; Brenda Jensen; David H. Sherr

J Immunol (2003) 170 (10): 4897–4904.

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Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells ¹

Anna K. Nowak; Richard A. Lake; Amanda L. Marzo; Bernadette Scott; William R. Heath; Edward J. Collins; Jeffrey A. Frelinger; Bruce W. S. Robinson

J Immunol (2003) 170 (10): 4905–4913.

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Two Regions of Down-Regulation in the IgE-Mediated Signaling Pathway in Human Basophils ¹

Donald MacGlashan, Jr.

J Immunol (2003) 170 (10): 4914–4925.

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The Lymphoid Past of Mouse Plasmacytoid Cells and Thymic Dendritic Cells ¹

Lynn Corcoran; Isabel Ferrero; David Vremec; Karen Lucas; Jason Waithman; Meredith O’Keeffe; Li Wu; Anne Wilson; Ken Shortman

J Immunol (2003) 170 (10): 4926–4932.

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Regulation of CD8⁺ T Cells Undergoing Primary and Secondary Responses to Infection in the Same Host ¹

Vladimir P. Badovinac; Kelly A. Nordyke Messingham; Sara E. Hamilton; John T. Harty

J Immunol (2003) 170 (10): 4933–4942.

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Prostaglandin D₂ Affects the Maturation of Human Monocyte-Derived Dendritic Cells: Consequence on the Polarization of Naive Th Cells ¹

Philippe Gosset; Fabrice Bureau; Veronique Angeli; Muriel Pichavant; Christelle Faveeuw; André-Bernard Tonnel; François Trottein

J Immunol (2003) 170 (10): 4943–4952.

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Differential Roles of CB1 and CB2 Cannabinoid Receptors in Mast Cells ¹

Maria-Teresa Samson; Andrea Small-Howard; Lori M. N. Shimoda; Murielle Koblan-Huberson; Alexander J. Stokes; Helen Turner

J Immunol (2003) 170 (10): 4953–4962.

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Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and Survival ¹

Elissa K. Deenick; Amanda V. Gett; Philip D. Hodgkin

J Immunol (2003) 170 (10): 4963–4972.

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Active Form of Notch Members Can Enforce T Lymphopoiesis on Lymphoid Progenitors in the Monolayer Culture Specific for B Cell Development ¹

Katsuto Hozumi; Natsumi Abe; Shigeru Chiba; Hisamaru Hirai; Sonoko Habu

J Immunol (2003) 170 (10): 4973–4979.

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Histone Deacetylation, But Not Hypermethylation, Modifies Class II Transactivator and MHC Class II Gene Expression in Squamous Cell Carcinomas ¹

Takayuki Kanaseki; Hideyuki Ikeda; Yukio Takamura; Minoru Toyota; Yoshihiko Hirohashi; Takashi Tokino; Tetsuo Himi; Noriyuki Sato

J Immunol (2003) 170 (10): 4980–4985.

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Differential Control of Cell Cycle, Proliferation, and Survival of Primary T Lymphocytes by Purine and Pyrimidine Nucleotides ¹

Laurence Quéméneur; Luc-Marie Gerland; Monique Flacher; Martine Ffrench; Jean-Pierre Revillard; Laurent Genestier

J Immunol (2003) 170 (10): 4986–4995.

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Mechanisms of Accelerated Immune-Mediated Diabetes Resulting from Islet β Cell Expression of a Fas Ligand Transgene ¹

Diego G. Silva; Nikolai Petrovsky; Luis Socha; Robyn Slattery; Paul Gatenby; Brett Charlton

J Immunol (2003) 170 (10): 4996–5002.

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IL-18 and IL-12 Signal Through the NF-κB Pathway to Induce NK-1R Expression on T Cells ¹

Joel V. Weinstock; Arthur Blum; Ahmed Metwali; David Elliott; Razvan Arsenescu

J Immunol (2003) 170 (10): 5003–5007.

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Superantigen-Induced Regulatory T Cells Display Different Suppressive Functions in the Presence or Absence of Natural CD4⁺CD25⁺ Regulatory T Cells In Vivo ¹

Susanna Grundström; Lukas Cederbom; Anette Sundstedt; Peter Scheipers; Fredrik Ivars

J Immunol (2003) 170 (10): 5008–5017.

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IL-15 Promotes the Survival of Naive and Memory Phenotype CD8⁺ T Cells ¹

Marion Berard; Katja Brandt; Silvia Bulfone Paus; David F. Tough

J Immunol (2003) 170 (10): 5018–5026.

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A Peptide from Heat Shock Protein 60 Is the Dominant Peptide Bound To Qa-1 in the Absence of the MHC Class Ia Leader Sequence Peptide Qdm ¹

Adrian Davies; Suzanne Kalb; Bitao Liang; Carla J. Aldrich; François A. Lemonnier; Hong Jiang; Robert Cotter; Mark J. Soloski

J Immunol (2003) 170 (10): 5027–5033.

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Extracellular Matrix Conditions T Cells for Adhesion to Tissue Interstitium ¹

Kimberly A. Krivacic; Alan D. Levine

J Immunol (2003) 170 (10): 5034–5044.

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Mast Cells Express Novel Functional IL-15 Receptor α Isoforms ¹

Elena Bulanova; Vadim Budagian; Zane Orinska; Hans Krause; Ralf Paus; Silvia Bulfone-Paus

J Immunol (2003) 170 (10): 5045–5055.

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Attenuation of Immunological Symptoms of Allergic Asthma in Mice Lacking the Tyrosine Kinase ITK ¹

Cynthia Mueller; Avery August

J Immunol (2003) 170 (10): 5056–5063.

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Nitric Oxide-Independent CTL Suppression during Tumor Progression: Association with Arginase-Producing (M2) Myeloid Cells ¹

Yuanqing Liu; Jo A. Van Ginderachter; Lea Brys; Patrick De Baetselier; Geert Raes; Anja B. Geldhof

J Immunol (2003) 170 (10): 5064–5074.

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Early IL-2 Production by Mouse Dendritic Cells Is the Result of Microbial-Induced Priming ¹

Francesca Granucci; Sonia Feau; Véronique Angeli; François Trottein; Paola Ricciardi-Castagnoli

J Immunol (2003) 170 (10): 5075–5081.

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TNF Enhances CD4⁺ T Cell Alloproliferation, IFN-γ Responses, and Intestinal Graft-Versus-Host Disease by IL-12-Independent Mechanisms ¹

Geri R. Brown; Edward L. Lee; Dwain L. Thiele

J Immunol (2003) 170 (10): 5082–5088.

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A Subset of Human Dendritic Cells in the T Cell Area of Mucosa-Associated Lymphoid Tissue with a High Potential to Produce TNF-α ¹

Annegret de Baey; Ines Mende; Gustavo Baretton; Axel Greiner; Wolfgang H. Hartl; Patrick A. Baeuerle; Helmut M. Diepolder

J Immunol (2003) 170 (10): 5089–5094.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Repertoire Shift in the Humoral Response to Phosphocholine-Keyhole Limpet Hemocyanin: V_H Somatic Mutation in Germinal Center B Cells Impairs T15 Ig Function ¹

Gregory D. Wiens; McKay Brown; Marvin B. Rittenberg

J Immunol (2003) 170 (10): 5095–5102.

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Prevalent Role of TCR α-Chain in the Selection of the Preimmune Repertoire Specific for a Human Tumor-Associated Self-Antigen ¹

Pierre-Yves Dietrich; Frédérique-Anne Le Gal; Valérie Dutoit; Mikäel J. Pittet; Lydie Trautman; Alfred Zippelius; Isabelle Cognet; Valérie Widmer; Paul R. Walker; Olivier Michielin; Philippe Guillaume; Thierry Connerotte; Francine Jotereau; Pierre G. Coulie; Pedro Romero; Jean-Charles Cerottini; Marc Bonneville; Danila Valmori

J Immunol (2003) 170 (10): 5103–5109.

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Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate ¹

Valérie Dutoit; Philippe Guillaume; Maha Ayyoub; Charles S. Hesdorffer; Immanuel F. Luescher; Danila Valmori

J Immunol (2003) 170 (10): 5110–5117.

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Molecular Identification and Functional Expression of μ₃, a Novel Alternatively Spliced Variant of the Human μ Opiate Receptor Gene ¹

Patrick Cadet; Kirk J. Mantione; George B. Stefano

J Immunol (2003) 170 (10): 5118–5123.

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DNA Methylation and Chromatin Structure Regulate T Cell Perforin Gene Expression ¹

Qianjin Lu; Ailing Wu; Donna Ray; Chun Deng; John Attwood; Samir Hanash; Matthew Pipkin; Mathias Lichtenheld; Bruce Richardson

J Immunol (2003) 170 (10): 5124–5132.

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The H4^b Minor Histocompatibility Antigen Is Caused by a Combination of Genetically Determined and Posttranslational Modifications ¹

Rajwardhan Yadav; Yoshitaka Yoshimura; Alina Boesteanu; Gregory J. Christianson; Wilfred U. Ajayi; R. Shashidharamurthy; Aleksandar K. Stanic; Derry C. Roopenian; Sebastian Joyce

J Immunol (2003) 170 (10): 5133–5142.

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Selective Regulation of Mature IgG1 Transcription by CD86 and β₂-Adrenergic Receptor Stimulation ¹

Joseph R. Podojil; Virginia M. Sanders

J Immunol (2003) 170 (10): 5143–5151.

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HOST DEFENSE

The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility to Leishmania major¹

Nancy Noben-Trauth; Rosalia Lira; Hisashi Nagase; William E. Paul; David L. Sacks

J Immunol (2003) 170 (10): 5152–5158.

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Toll-Like Receptor 2 (TLR2) and TLR9 Signaling Results in HIV-Long Terminal Repeat Trans-Activation and HIV Replication in HIV-1 Transgenic Mouse Spleen Cells: Implications of Simultaneous Activation of TLRs on HIV Replication ¹

Ozlem Equils; Marco L. Schito; Hiase Karahashi; Zeynep Madak; Ayse Yarali; Kathrin S. Michelsen; Alan Sher; Moshe Arditi

J Immunol (2003) 170 (10): 5159–5164.

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The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells ¹

Terry K. Means; Fumitaka Hayashi; Kelly D. Smith; Alan Aderem; Andrew D. Luster

J Immunol (2003) 170 (10): 5165–5175.

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The Induction of HIV Gag-Specific CD8⁺ T Cells in the Spleen and Gut-Associated Lymphoid Tissue by Parenteral or Mucosal Immunization with Recombinant Listeria monocytogenes HIV Gag ¹

Christian Peters; Xiaohui Peng; Dennis Douven; Zhen-Kun Pan; Yvonne Paterson

J Immunol (2003) 170 (10): 5176–5187.

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A Single Heteroclitic Epitope Determines Cancer Immunity After Xenogeneic DNA Immunization Against a Tumor Differentiation Antigen ¹

Jason S. Gold; Cristina R. Ferrone; Jose A. Guevara-Patiño; William G. Hawkins; Ruben Dyall; Manuel E. Engelhorn; Jedd D. Wolchok; Jonathan J. Lewis; Alan N. Houghton

J Immunol (2003) 170 (10): 5188–5194.

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Monocyte-Derived Dendritic Cells Generated After a Short-Term Culture with IFN-α and Granulocyte-Macrophage Colony-Stimulating Factor Stimulate a Potent Epstein-Barr Virus-Specific CD8⁺ T Cell Response ¹

Laura Santodonato; Giuseppina D’Agostino; Roberto Nisini; Sabrina Mariotti; Domenica M. Monque; Massimo Spada; Laura Lattanzi; Maria Paola Perrone; Mauro Andreotti; Filippo Belardelli; Maria Ferrantini

J Immunol (2003) 170 (10): 5195–5202.

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Cumulative Toll-Like Receptor Activation in Human Macrophages Treated with Whole Bacteria ¹

Gerard J. Nau; Ann Schlesinger; Joan F. L. Richmond; Richard A. Young

J Immunol (2003) 170 (10): 5203–5209.

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The Lymphotoxin β Receptor Is Critically Involved in Controlling Infections with the Intracellular Pathogens Mycobacterium tuberculosis and Listeria monocytogenes¹

Stefan Ehlers; Christoph Hölscher; Stefanie Scheu; Christine Tertilt; Thomas Hehlgans; Johanna Suwinski; Robert Endres; Klaus Pfeffer

J Immunol (2003) 170 (10): 5210–5218.

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Macrophages Restrict Pseudomonas aeruginosa Growth, Regulate Polymorphonuclear Neutrophil Influx, and Balance Pro- and Anti-Inflammatory Cytokines in BALB/c Mice ¹

Sharon A. McClellan; Xi Huang; Ronald P. Barrett; Nico van Rooijen; Linda D. Hazlett

J Immunol (2003) 170 (10): 5219–5227.

Abstract

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Neutrophilia in LFA-1-Deficient Mice Confers Resistance to Listeriosis: Possible Contribution of Granulocyte-Colony-Stimulating Factor and IL-17 ¹

Mamiko Miyamoto; Masashi Emoto; Yoshiko Emoto; Volker Brinkmann; Izumi Yoshizawa; Peter Seiler; Peter Aichele; Eiji Kita; Stefan H. E. Kaufmann

J Immunol (2003) 170 (10): 5228–5234.

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INFLAMMATION

Chemotactic Factor-Induced Recruitment and Activation of Tec Family Kinases in Human Neutrophils. II. Effects of LFM-A13, a Specific Btk Inhibitor ¹

Caroline Gilbert; Sylvain Levasseur; Philippe Desaulniers; Andrée-Anne Dusseault; Nathalie Thibault; Sylvain G. Bourgoin; Paul H. Naccache

J Immunol (2003) 170 (10): 5235–5243.

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Duffy Antigen Facilitates Movement of Chemokine Across the Endothelium In Vitro and Promotes Neutrophil Transmigration In Vitro and In Vivo ¹

Janet S. Lee; Charles W. Frevert; Mark M. Wurfel; Stephen C. Peiper; Venus A. Wong; Kimberley K. Ballman; John T. Ruzinski; Johng S. Rhim; Thomas R. Martin; Richard B. Goodman

J Immunol (2003) 170 (10): 5244–5251.

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C-C Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Directly Inhibits NKT Cell IL-4 Production and Is Hepatoprotective in T Cell-Mediated Hepatitis in the Mouse ¹

Maureen N. Ajuebor; Cory M. Hogaboam; Tai Le; Mark G. Swain

J Immunol (2003) 170 (10): 5252–5259.

Abstract

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Different Modes of IL-10 and TGF-β to Inhibit Cytokine-Dependent IFN-γ Production: Consequences for Reversal of Lipopolysaccharide Desensitization ¹

Martina Schröder; Christian Meisel; Katharina Buhl; Nina Profanter; Nadine Sievert; Hans-Dieter Volk; Gerald Grütz

J Immunol (2003) 170 (10): 5260–5267.

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Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span ¹

Ian Sabroe; Lynne R. Prince; Elizabeth C. Jones; Malcolm J. Horsburgh; Simon J. Foster; Stefanie N. Vogel; Steven K. Dower; Moira K. B. Whyte

J Immunol (2003) 170 (10): 5268–5275.

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Calcium-Independent Phospholipase A₂ Is Required for Lysozyme Secretion in U937 Promonocytes ¹

María A. Balboa; Yolanda Sáez; Jesús Balsinde

J Immunol (2003) 170 (10): 5276–5280.

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Amyloid Peptide-Induced Cytokine and Chemokine Expression in THP-1 Monocytes Is Blocked by Small Inhibitory RNA Duplexes for Early Growth Response-1 Messenger RNA

Ranjit K. Giri; Suresh K. Selvaraj; Vijay K. Kalra

J Immunol (2003) 170 (10): 5281–5294.

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Peroxisome Proliferator-Activated Receptor γ Inhibits the Migration of Dendritic Cells: Consequences for the Immune Response ¹

Véronique Angeli; Hamida Hammad; Bart Staels; Monique Capron; Bart N. Lambrecht; François Trottein

J Immunol (2003) 170 (10): 5295–5301.

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Akt Phosphorylates p47^phox and Mediates Respiratory Burst Activity in Human Neutrophils ¹

Qingdan Chen; David W. Powell; Madhavi J. Rane; Saurabh Singh; Waseem Butt; Jon B. Klein; Kenneth R. McLeish

J Immunol (2003) 170 (10): 5302–5308.

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Expression and Production of the CXC Chemokine Growth-Related Oncogene-α by Human Eosinophils ¹

Terese Persson-Dajotoy; Pia Andersson; Anders Bjartell; Jero Calafat; Arne Egesten

J Immunol (2003) 170 (10): 5309–5316.

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CLINICAL IMMUNOLOGY

Hybrids of Dendritic Cells and Tumor Cells Generated by Electrofusion Simultaneously Present Immunodominant Epitopes from Multiple Human Tumor-Associated Antigens in the Context of MHC Class I and Class II Molecules ¹

Maria R. Parkhurst; Cormac DePan; John P. Riley; Steven A. Rosenberg; Suyu Shu

J Immunol (2003) 170 (10): 5317–5325.

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Immunization with a Xenobiotic 6-Bromohexanoate Bovine Serum Albumin Conjugate Induces Antimitochondrial Antibodies ¹

Patrick S. C. Leung; Chao Quan; Ogyi Park; Judy Van de Water; Mark J. Kurth; Michael H. Nantz; Aftab A. Ansari; Ross L. Coppel; Kit S. Lam; M. Eric Gershwin

J Immunol (2003) 170 (10): 5326–5332.

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CORRECTIONS

CORRECTION

J Immunol (2003) 170 (10): 5333.

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Issues

IN THIS ISSUE

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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