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J Immunol (2004) 173 (10): 5899–5900.

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BRIEF REVIEWS

TLR Signaling: An Emerging Bridge from Innate Immunity to Atherogenesis ¹

Kathrin S. Michelsen; Terence M. Doherty; Prediman K. Shah; Moshe Arditi

J Immunol (2004) 173 (10): 5901–5907.

Abstract

View articletitled, TLR Signaling: An Emerging Bridge from Innate Immunity to Atherogenesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CUTTING EDGE

Cutting Edge: Human Eosinophils Regulate T Cell Subset Selection through Indoleamine 2,3-Dioxygenase ¹

Solomon O. Odemuyiwa; Ahmad Ghahary; Yunyuan Li; Lakshmi Puttagunta; Joo Eun Lee; Sorin Musat-Marcu; Aziz Ghahary; Redwan Moqbel

J Immunol (2004) 173 (10): 5909–5913.

Abstract

View articletitled, Cutting Edge: Human Eosinophils Regulate T Cell Subset Selection through Indoleamine 2,3-Dioxygenase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Bone Morphogenetic Protein Antagonists Drm/Gremlin and Dan Interact with Slits and Act as Negative Regulators of Monocyte Chemotaxis ¹^²

Bo Chen; Donald G. Blair; Sergei Plisov; Gennady Vasiliev; Alan O. Perantoni; Qian Chen; Meropi Athanasiou; Jane Y. Wu; Joost J. Oppenheim; De Yang

J Immunol (2004) 173 (10): 5914–5917.

Abstract

View articletitled, Cutting Edge: Bone Morphogenetic Protein Antagonists Drm/Gremlin and Dan Interact with Slits and Act as Negative Regulators of Monocyte Chemotaxis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Cutting Edge: Immunity and IFN-γ Production during Listeria monocytogenes Infection in the Absence of T-bet ¹

Sing Sing Way; Christopher B. Wilson

J Immunol (2004) 173 (10): 5918–5922.

Abstract

View articletitled, Cutting Edge: Immunity and IFN-γ Production during Listeria monocytogenes Infection in the Absence of T-bet<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Tumor-Specific CTL Are Constitutively Cross-Armed in Draining Lymph Nodes and Transiently Disseminate to Mediate Tumor Regression following Systemic CD40 Activation ¹

Philip A. Stumbles; Robyn Himbeck; Jeffrey A. Frelinger; Edward J. Collins; Richard A. Lake; Bruce W. S. Robinson

J Immunol (2004) 173 (10): 5923–5928.

Abstract

View articletitled, Cutting Edge: Tumor-Specific CTL Are Constitutively Cross-Armed in Draining Lymph Nodes and Transiently Disseminate to Mediate Tumor Regression following Systemic CD40 Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Cross-Presentation of Cell-Associated Antigens to MHC Class I Molecule Is Regulated by a Major Transcription Factor for Heat Shock Proteins ¹

Hong Zheng; Zihai Li

J Immunol (2004) 173 (10): 5929–5933.

Abstract

View articletitled, Cutting Edge: Cross-Presentation of Cell-Associated Antigens to MHC Class I Molecule Is Regulated by a Major Transcription Factor for Heat Shock Proteins<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Replication-Dependent Potent IFN-α Induction in Human Plasmacytoid Dendritic Cells by a Single-Stranded RNA Virus ¹

Veit Hornung; Jörg Schlender; Margit Guenthner-Biller; Simon Rothenfusser; Stefan Endres; Karl-Klaus Conzelmann; Gunther Hartmann

J Immunol (2004) 173 (10): 5935–5943.

Abstract

View articletitled, Replication-Dependent Potent IFN-α Induction in Human Plasmacytoid Dendritic Cells by a Single-Stranded RNA Virus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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4-1BB and OX40 Act Independently to Facilitate Robust CD8 and CD4 Recall Responses ¹

Wojciech Dawicki; Edward M. Bertram; Arlene H. Sharpe; Tania H. Watts

J Immunol (2004) 173 (10): 5944–5951.

Abstract

View articletitled, 4-1BB and OX40 Act Independently to Facilitate Robust CD8 and CD4 Recall Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mechanism of Prostaglandin (PG)E₂-Induced Prolactin Expression in Human T Cells: Cooperation of Two PGE₂ Receptor Subtypes, E-Prostanoid (EP) 3 and EP4, Via Calcium- and Cyclic Adenosine 5′-Monophosphate-Mediated Signaling Pathways ¹

Sarah Gerlo; Peggy Verdood; Birgit Gellersen; Elisabeth L. Hooghe-Peters; Ron Kooijman

J Immunol (2004) 173 (10): 5952–5962.

Abstract

View articletitled, Mechanism of Prostaglandin (PG)E2-Induced Prolactin Expression in Human T Cells: Cooperation of Two PGE2 Receptor Subtypes, E-Prostanoid (EP) 3 and EP4, Via Calcium- and Cyclic Adenosine 5′-Monophosphate-Mediated Signaling Pathways<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Eosinophil Adhesion to Cholinergic IMR-32 Cells Protects against Induced Neuronal Apoptosis ¹

Ross K. Morgan; Paul J. Kingham; Marie Therese Walsh; David C. Curran; Niamh Durcan; W. Graham McLean; Richard W. Costello

J Immunol (2004) 173 (10): 5963–5970.

Abstract

View articletitled, Eosinophil Adhesion to Cholinergic IMR-32 Cells Protects against Induced Neuronal Apoptosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rac2-Deficient Murine Macrophages Have Selective Defects in Superoxide Production and Phagocytosis of Opsonized Particles ¹

Akira Yamauchi; Chaekyun Kim; Shijun Li; Christophe C. Marchal; Jason Towe; Simon J. Atkinson; Mary C. Dinauer

J Immunol (2004) 173 (10): 5971–5979.

Abstract

View articletitled, Rac2-Deficient Murine Macrophages Have Selective Defects in Superoxide Production and Phagocytosis of Opsonized Particles<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Impaired Receptor Editing in the Primary B Cell Repertoire of BASH-Deficient Mice ¹

Katsuhiko Hayashi; Takuya Nojima; Ryo Goitsuka; Daisuke Kitamura

J Immunol (2004) 173 (10): 5980–5988.

Abstract

View articletitled, Impaired Receptor Editing in the Primary B Cell Repertoire of BASH-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Extract of Reishi Polysaccharides Induces Cytokine Expression via TLR4-Modulated Protein Kinase Signaling Pathways ¹

Hsien-Yeh Hsu; Kuo-Feng Hua; Chun-Cheng Lin; Chun-Hung Lin; Jason Hsu; Chi-Huey Wong

J Immunol (2004) 173 (10): 5989–5999.

Abstract

View articletitled, Extract of Reishi Polysaccharides Induces Cytokine Expression via TLR4-Modulated Protein Kinase Signaling Pathways<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD63 as an Activation-Linked T Cell Costimulatory Element ¹

Katharina Pfistershammer; Otto Majdic; Johannes Stöckl; Gerhard Zlabinger; Stefanie Kirchberger; Peter Steinberger; Walter Knapp

J Immunol (2004) 173 (10): 6000–6008.

Abstract

View articletitled, CD63 as an Activation-Linked T Cell Costimulatory Element<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of B Cell-Mediated T Cell Costimulation in the Efficacy of the T Cell Retargeting Bispecific Antibody BIS20x3 ¹

Alja J. Stel; Bart-Jan Kroesen; Susan Jacobs; Herman Groen; Lou F. M. H. de Leij; Hanneke C. Kluin-Nelemans; Sebo Withoff

J Immunol (2004) 173 (10): 6009–6016.

Abstract

View articletitled, The Role of B Cell-Mediated T Cell Costimulation in the Efficacy of the T Cell Retargeting Bispecific Antibody BIS20x3<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rescuing Melanoma Epitope-Specific Cytolytic T Lymphocytes from Activation-Induced Cell Death, by SP600125, an Inhibitor of JNK: Implications in Cancer Immunotherapy ¹

Shikhar Mehrotra; Arvind Chhabra; Subhasis Chattopadhyay; David I. Dorsky; Nitya G. Chakraborty; Bijay Mukherji

J Immunol (2004) 173 (10): 6017–6024.

Abstract

View articletitled, Rescuing Melanoma Epitope-Specific Cytolytic T Lymphocytes from Activation-Induced Cell Death, by SP600125, an Inhibitor of JNK: Implications in Cancer Immunotherapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Immunization Site of Cytokine-Secreting Tumor Cell Vaccines Influences the Trafficking of Tumor-Specific T Lymphocytes and Antitumor Efficacy against Regional Tumors ¹

Chun-Jung Chang; Kuo-Feng Tai; Steve Roffler; Lih-Hwa Hwang

J Immunol (2004) 173 (10): 6025–6032.

Abstract

View articletitled, The Immunization Site of Cytokine-Secreting Tumor Cell Vaccines Influences the Trafficking of Tumor-Specific T Lymphocytes and Antitumor Efficacy against Regional Tumors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Final Antigenic Melan-A Peptides Produced Directly by the Proteasomes Are Preferentially Selected for Presentation by HLA-A*0201 in Melanoma Cells ¹

Laurence Chapatte; Catherine Servis; Danila Valmori; Odile Burlet-Schiltz; Johanna Dayer; Bernard Monsarrat; Pedro Romero; Frédéric Lévy

J Immunol (2004) 173 (10): 6033–6040.

Abstract

View articletitled, Final Antigenic Melan-A Peptides Produced Directly by the Proteasomes Are Preferentially Selected for Presentation by HLA-A*0201 in Melanoma Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evidence of a Novel IL-2/15Rβ-Targeted Cytokine Involved in Homeostatic Proliferation of Memory CD8⁺ T Cells ¹

Daisuke Kamimura; Naoko Ueda; Yukihisa Sawa; Shinji Hachida; Toru Atsumi; Takayuki Nakagawa; Shin-ichiro Sawa; Gui-Hua Jin; Haruhiko Suzuki; Katsuhiko Ishihara; Masaaki Murakami; Toshio Hirano

J Immunol (2004) 173 (10): 6041–6049.

Abstract

View articletitled, Evidence of a Novel IL-2/15Rβ-Targeted Cytokine Involved in Homeostatic Proliferation of Memory CD8+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mechanisms of Peritoneal B-1a Cells Accumulation Induced by Murine Lupus Susceptibility Locus Sle2¹

Zhiwei Xu; Edward J. Butfiloski; Eric S. Sobel; Laurence Morel

J Immunol (2004) 173 (10): 6050–6058.

Abstract

View articletitled, Mechanisms of Peritoneal B-1a Cells Accumulation Induced by Murine Lupus Susceptibility Locus Sle2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Bystander Suppression by Feeding Antigen Occurs despite Normal Clonal Expansion of the Bystander T Cell Population ¹

Owain R. Millington; Allan McI. Mowat; Paul Garside

J Immunol (2004) 173 (10): 6059–6064.

Abstract

View articletitled, Induction of Bystander Suppression by Feeding Antigen Occurs despite Normal Clonal Expansion of the Bystander T Cell Population<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Homeostatic Proliferation of a Qa-1^b-Restricted T Cell: A Distinction between the Ligands Required for Positive Selection and for Proliferation in Lymphopenic Hosts ¹

Barbara A. Sullivan; Lisa M. Reed-Loisel; Gilbert J. Kersh; Peter E. Jensen

J Immunol (2004) 173 (10): 6065–6071.

Abstract

View articletitled, Homeostatic Proliferation of a Qa-1b-Restricted T Cell: A Distinction between the Ligands Required for Positive Selection and for Proliferation in Lymphopenic Hosts<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Negative Regulation of NK Cell Activities by Inhibitory Receptor CD94/NKG2A Leads to Altered NK Cell-Induced Modulation of Dendritic Cell Functions in Chronic Hepatitis C Virus Infection ¹

Masahisa Jinushi; Tetsuo Takehara; Tomohide Tatsumi; Tatsuya Kanto; Takuya Miyagi; Takahiro Suzuki; Yoshiyuki Kanazawa; Naoki Hiramatsu; Norio Hayashi

J Immunol (2004) 173 (10): 6072–6081.

Abstract

View articletitled, Negative Regulation of NK Cell Activities by Inhibitory Receptor CD94/NKG2A Leads to Altered NK Cell-Induced Modulation of Dendritic Cell Functions in Chronic Hepatitis C Virus Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vasoactive Intestinal Peptide Modulates Langerhans Cell Immune Function ¹

Sreedevi Kodali; Wanhong Ding; Jing Huang; Kristina Seiffert; John A. Wagner; Richard D. Granstein

J Immunol (2004) 173 (10): 6082–6088.

Abstract

View articletitled, Vasoactive Intestinal Peptide Modulates Langerhans Cell Immune Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antigen Targeting to CD11b Allows Efficient Presentation of CD4⁺ and CD8⁺ T Cell Epitopes and In Vivo Th1-Polarized T Cell Priming ¹

Géraldine Schlecht; Jirina Loucka; Hossain Najar; Peter Sebo; Claude Leclerc

J Immunol (2004) 173 (10): 6089–6097.

Abstract

View articletitled, Antigen Targeting to CD11b Allows Efficient Presentation of CD4+ and CD8+ T Cell Epitopes and In Vivo Th1-Polarized T Cell Priming<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Augmentation of T Cell Levels and Responses Induced by Androgen Deprivation ¹

Anja C. Roden; Michael T. Moser; Samuel D. Tri; Maria Mercader; Susan M. Kuntz; Haidong Dong; Arthur A. Hurwitz; David J. McKean; Esteban Celis; Bradley C. Leibovich; James P. Allison; Eugene D. Kwon

J Immunol (2004) 173 (10): 6098–6108.

Abstract

View articletitled, Augmentation of T Cell Levels and Responses Induced by Androgen Deprivation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A General Survey of Thymocyte Differentiation by Transcriptional Analysis of Knockout Mouse Models ¹

Denis Puthier; Florence Joly; Magali Irla; Murielle Saade; Geneviève Victorero; Béatrice Loriod; Catherine Nguyen

J Immunol (2004) 173 (10): 6109–6118.

Abstract

View articletitled, A General Survey of Thymocyte Differentiation by Transcriptional Analysis of Knockout Mouse Models<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Supplementary data

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Regulated Recruitment of MHC Class II and Costimulatory Molecules to Lipid Rafts in Dendritic Cells ¹

Christian O. Meyer zum Bueschenfelde; Julia Unternaehrer; Ira Mellman; Kim Bottomly

J Immunol (2004) 173 (10): 6119–6124.

Abstract

View articletitled, Regulated Recruitment of MHC Class II and Costimulatory Molecules to Lipid Rafts in Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression and Characterization of a Novel CD6 Ligand in Cells Derived from Joint and Epithelial Tissues ¹

Mohammad K. Saifullah; David A. Fox; Sujata Sarkar; Syed M. A. Abidi; Judith Endres; Joseph Piktel; Tariq M. Haqqi; Nora G. Singer

J Immunol (2004) 173 (10): 6125–6133.

Abstract

View articletitled, Expression and Characterization of a Novel CD6 Ligand in Cells Derived from Joint and Epithelial Tissues<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Ribonuclease A Superfamily Members, Eosinophil-Derived Neurotoxin and Pancreatic Ribonuclease, Induce Dendritic Cell Maturation and Activation ¹

De Yang; Qian Chen; Helene F. Rosenberg; Susanna M. Rybak; Dianne L. Newton; Zhao Yuan Wang; Qin Fu; Velizar T. Tchernev; Minjuan Wang; Barry Schweitzer; Stephen F. Kingsmore; Dhavalkumar D. Patel; Joost J. Oppenheim; O. M. Zack Howard

J Immunol (2004) 173 (10): 6134–6142.

Abstract

View articletitled, Human Ribonuclease A Superfamily Members, Eosinophil-Derived Neurotoxin and Pancreatic Ribonuclease, Induce Dendritic Cell Maturation and Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vesicle Size Influences the Trafficking, Processing, and Presentation of Antigens in Lipid Vesicles ¹

James M. Brewer; Kevin G. J. Pollock; Laurence Tetley; David G. Russell

J Immunol (2004) 173 (10): 6143–6150.

Abstract

View articletitled, Vesicle Size Influences the Trafficking, Processing, and Presentation of Antigens in Lipid Vesicles<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dietary Docosahexaenoic Acid Suppresses T Cell Protein Kinase Cθ Lipid Raft Recruitment and IL-2 Production ¹

Yang-Yi Fan; Lan H. Ly; Rola Barhoumi; David N. McMurray; Robert S. Chapkin

J Immunol (2004) 173 (10): 6151–6160.

Abstract

View articletitled, Dietary Docosahexaenoic Acid Suppresses T Cell Protein Kinase Cθ Lipid Raft Recruitment and IL-2 Production<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IκB Kinase Complex α Kinase Activity Controls Chemokine and High Endothelial Venule Gene Expression in Lymph Nodes and Nasal-Associated Lymphoid Tissue ¹

Danielle L. Drayton; Giuseppina Bonizzi; Xiaoyan Ying; Shan Liao; Michael Karin; Nancy H. Ruddle

J Immunol (2004) 173 (10): 6161–6168.

Abstract

View articletitled, IκB Kinase Complex α Kinase Activity Controls Chemokine and High Endothelial Venule Gene Expression in Lymph Nodes and Nasal-Associated Lymphoid Tissue<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Follicular Dendritic Cell Regulation of CXCR4-Mediated Germinal Center CD4 T Cell Migration ¹

Jacob D. Estes; Tyler C. Thacker; Denise L. Hampton; Sariah A. Kell; Brandon F. Keele; Emily A. Palenske; Kirk M. Druey; Gregory F. Burton

J Immunol (2004) 173 (10): 6169–6178.

Abstract

View articletitled, Follicular Dendritic Cell Regulation of CXCR4-Mediated Germinal Center CD4 T Cell Migration<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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B Cells Expressing Bcl-2 and a Signaling-Impaired BAFF-Specific Receptor Fail to Mature and Are Deficient in the Formation of Lymphoid Follicles and Germinal Centers ¹

Ziaur S. M. Rahman; Tim Manser

J Immunol (2004) 173 (10): 6179–6188.

Abstract

View articletitled, B Cells Expressing Bcl-2 and a Signaling-Impaired BAFF-Specific Receptor Fail to Mature and Are Deficient in the Formation of Lymphoid Follicles and Germinal Centers<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

PIASy-Deficient Mice Display Modest Defects in IFN and Wnt Signaling ¹

Wera Roth; Claudio Sustmann; Matthias Kieslinger; Andrea Gilmozzi; Denis Irmer; Elisabeth Kremmer; Chris Turck; Rudolf Grosschedl

J Immunol (2004) 173 (10): 6189–6199.

Abstract

View articletitled, PIASy-Deficient Mice Display Modest Defects in IFN and Wnt Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Long Distance Control of MHC Class II Expression by Multiple Distal Enhancers Regulated by Regulatory Factor X Complex and CIITA ¹

Michal Krawczyk; Nicolas Peyraud; Natalia Rybtsova; Krzysztof Masternak; Philipp Bucher; Emmanuèle Barras; Walter Reith

J Immunol (2004) 173 (10): 6200–6210.

Abstract

View articletitled, Long Distance Control of MHC Class II Expression by Multiple Distal Enhancers Regulated by Regulatory Factor X Complex and CIITA<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Gene Expression Modulated by the Cytoplasmic Domain of FcγRIa (CD64) α-Chain ¹

Hongwei Qin; Jeffrey C. Edberg; Andrew W. Gibson; Grier P. Page; Lihong Teng; Robert P. Kimberly

J Immunol (2004) 173 (10): 6211–6219.

Abstract

View articletitled, Differential Gene Expression Modulated by the Cytoplasmic Domain of FcγRIa (CD64) α-Chain<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Bax N Terminus Is Required for Negative Regulation by the Mitogen-Activated Protein Kinase Kinase and Akt Signaling Pathways in T Cells ¹

Neha Parikh; Hadassah Sade; Leo Kurian; Apurva Sarin

J Immunol (2004) 173 (10): 6220–6227.

Abstract

View articletitled, The Bax N Terminus Is Required for Negative Regulation by the Mitogen-Activated Protein Kinase Kinase and Akt Signaling Pathways in T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HIV-1 Tat-Mediated Effects on Focal Adhesion Assembly and Permeability in Brain Microvascular Endothelial Cells ¹

Hava Karsenty Avraham; Shuxian Jiang; Tae-Hee Lee; Om Prakash; Shalom Avraham

J Immunol (2004) 173 (10): 6228–6233.

Abstract

View articletitled, HIV-1 Tat-Mediated Effects on Focal Adhesion Assembly and Permeability in Brain Microvascular Endothelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification and Partial Characterization of a Variant of Human CXCR3 Generated by Posttranscriptional Exon Skipping ¹

Jan Erik Ehlert; Christina A. Addison; Marie D. Burdick; Steven L. Kunkel; Robert M. Strieter

J Immunol (2004) 173 (10): 6234–6240.

Abstract

View articletitled, Identification and Partial Characterization of a Variant of Human CXCR3 Generated by Posttranscriptional Exon Skipping<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Enhancer Role of STAT5 in CD2 Activation of IFN-γ Gene Expression ¹

Rivkah Gonsky; Richard L. Deem; Jay Bream; Howard A. Young; Stephan R. Targan

J Immunol (2004) 173 (10): 6241–6247.

Abstract

View articletitled, Enhancer Role of STAT5 in CD2 Activation of IFN-γ Gene Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The 3′ Untranslated Region of the Membrane-Bound IL-1R Accessory Protein mRNA Confers Tissue-Specific Destabilization

Liselotte E. Jensen; Alexander S. Whitehead

J Immunol (2004) 173 (10): 6248–6258.

Abstract

View articletitled, The 3′ Untranslated Region of the Membrane-Bound IL-1R Accessory Protein mRNA Confers Tissue-Specific Destabilization

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The Functional Interaction of the β₂ Integrin Lymphocyte Function-Associated Antigen-1 with Junctional Adhesion Molecule-A Is Mediated by the I Domain ¹ ^²

Line Fraemohs; Rory R. Koenen; Georg Ostermann; Bo Heinemann; Christian Weber

J Immunol (2004) 173 (10): 6259–6264.

Abstract

View articletitled, The Functional Interaction of the β2 Integrin Lymphocyte Function-Associated Antigen-1 with Junctional Adhesion Molecule-A Is Mediated by the I Domain<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a> <a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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HOST DEFENSE

Differential Regulation of Primary and Secondary CD8⁺ T Cells in the Central Nervous System ¹

Chandran Ramakrishna; Stephen A. Stohlman; Roscoe A. Atkinson; David R. Hinton; Cornelia C. Bergmann

J Immunol (2004) 173 (10): 6265–6273.

Abstract

View articletitled, Differential Regulation of Primary and Secondary CD8+ T Cells in the Central Nervous System<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Involvement of FcγR I (CD64) in the Mechanism of HIV-1 Inhibition by Polyclonal IgG Purified from Infected Patients in Cultured Monocyte-Derived Macrophages ¹

Vincent Holl; Stéphane Hemmerter; Renaud Burrer; Sylvie Schmidt; Alain Bohbot; Anne-Marie Aubertin; Christiane Moog

J Immunol (2004) 173 (10): 6274–6283.

Abstract

View articletitled, Involvement of FcγR I (CD64) in the Mechanism of HIV-1 Inhibition by Polyclonal IgG Purified from Infected Patients in Cultured Monocyte-Derived Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Single-Epitope DNA Vaccination Prevents Exhaustion and Facilitates a Broad Antiviral CD8⁺ T Cell Response during Chronic Viral Infection ¹

Christina Bartholdy; Anette Stryhn; Jan Pravsgaard Christensen; Allan Randrup Thomsen

J Immunol (2004) 173 (10): 6284–6293.

Abstract

View articletitled, Single-Epitope DNA Vaccination Prevents Exhaustion and Facilitates a Broad Antiviral CD8+ T Cell Response during Chronic Viral Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Maximum Immunobioactivity of Murine Small Intestinal Intraepithelial Lymphocytes Resides in a Subpopulation of CD43⁺ T Cells ¹

Heuy-Ching Wang; Dina Montufar-Solis; Ba-Bie Teng; John R. Klein

J Immunol (2004) 173 (10): 6294–6302.

Abstract

View articletitled, Maximum Immunobioactivity of Murine Small Intestinal Intraepithelial Lymphocytes Resides in a Subpopulation of CD43+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Genetic Manipulation of Telomerase in HIV-Specific CD8⁺ T Cells: Enhanced Antiviral Functions Accompany the Increased Proliferative Potential and Telomere Length Stabilization ¹

Mirabelle Dagarag; Tandik Evazyan; Nagesh Rao; Rita B. Effros

J Immunol (2004) 173 (10): 6303–6311.

Abstract

View articletitled, Genetic Manipulation of Telomerase in HIV-Specific CD8+ T Cells: Enhanced Antiviral Functions Accompany the Increased Proliferative Potential and Telomere Length Stabilization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cmv1-Independent Antiviral Role of NK Cells Revealed in Murine Cytomegalovirus-Infected New Zealand White Mice ¹

Marisela Rodriguez; Pearl Sabastian; Patricia Clark; Michael G. Brown

J Immunol (2004) 173 (10): 6312–6318.

Abstract

View articletitled, Cmv1-Independent Antiviral Role of NK Cells Revealed in Murine Cytomegalovirus-Infected New Zealand White Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Pathogen-Induced Apoptotic Neutrophils Express Heat Shock Proteins and Elicit Activation of Human Macrophages ¹

Limin Zheng; Min He; Min Long; Robert Blomgran; Olle Stendahl

J Immunol (2004) 173 (10): 6319–6326.

Abstract

View articletitled, Pathogen-Induced Apoptotic Neutrophils Express Heat Shock Proteins and Elicit Activation of Human Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Hematopoietic Cells Are Required to Initiate a Chlamydia trachomatis-Specific CD8⁺ T Cell Response ¹

Lisa N. Steele; Zarine R. Balsara; Michael N. Starnbach

J Immunol (2004) 173 (10): 6327–6337.

Abstract

View articletitled, Hematopoietic Cells Are Required to Initiate a Chlamydia trachomatis-Specific CD8+ T Cell Response<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Multiple Roles of CLAN (Caspase-Associated Recruitment Domain, Leucine-Rich Repeat, and NAIP CIIA HET-E, and TP1-Containing Protein) in the Mammalian Innate Immune Response ¹

Jason S. Damiano; Ruchi M. Newman; John C. Reed

J Immunol (2004) 173 (10): 6338–6345.

Abstract

View articletitled, Multiple Roles of CLAN (Caspase-Associated Recruitment Domain, Leucine-Rich Repeat, and NAIP CIIA HET-E, and TP1-Containing Protein) in the Mammalian Innate Immune Response<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Helminth Infection Protects Mice from Anaphylaxis via IL-10-Producing B Cells ¹

Niamh E. Mangan; Rosemary E. Fallon; Philip Smith; Nico van Rooijen; Andrew N. McKenzie; Padraic G. Fallon

J Immunol (2004) 173 (10): 6346–6356.

Abstract

View articletitled, Helminth Infection Protects Mice from Anaphylaxis via IL-10-Producing B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis ¹

Jun Wang; Lisa Thorson; Richard W. Stokes; Michael Santosuosso; Kris Huygen; Anna Zganiacz; Mary Hitt; Zhou Xing

J Immunol (2004) 173 (10): 6357–6365.

Abstract

View articletitled, Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Apolipoprotein E Modulates Clearance of Apoptotic Bodies In Vitro and In Vivo, Resulting in a Systemic Proinflammatory State in Apolipoprotein E-Deficient Mice ¹

David J. Grainger; Jill Reckless; Elaine McKilligin

J Immunol (2004) 173 (10): 6366–6375.

Abstract

View articletitled, Apolipoprotein E Modulates Clearance of Apoptotic Bodies In Vitro and In Vivo, Resulting in a Systemic Proinflammatory State in Apolipoprotein E-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ethanol Blocks Leukocyte Recruitment and Endothelial Cell Activation In Vivo and In Vitro ¹

Rubina W. Saeed; Santosh Varma; Tina Peng; Kevin J. Tracey; Barbara Sherry; Christine N. Metz

J Immunol (2004) 173 (10): 6376–6383.

Abstract

View articletitled, Ethanol Blocks Leukocyte Recruitment and Endothelial Cell Activation In Vivo and In Vitro<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Intranasal Exposure of Mice to House Dust Mite Elicits Allergic Airway Inflammation via a GM-CSF-Mediated Mechanism ¹

Elizabeth C. Cates; Ramzi Fattouh; Jennifer Wattie; Mark D. Inman; Susanna Goncharova; Anthony J. Coyle; José-Carlos Gutierrez-Ramos; Manel Jordana

J Immunol (2004) 173 (10): 6384–6392.

Abstract

View articletitled, Intranasal Exposure of Mice to House Dust Mite Elicits Allergic Airway Inflammation via a GM-CSF-Mediated Mechanism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Novel Role of Cysteinyl Leukotrienes to Promote Dendritic Cell Activation in the Antigen-Induced Immune Responses in the Lung

Katsuhide Okunishi; Makoto Dohi; Kazuyuki Nakagome; Ryoichi Tanaka; Kazuhiko Yamamoto

J Immunol (2004) 173 (10): 6393–6402.

Abstract

View articletitled, A Novel Role of Cysteinyl Leukotrienes to Promote Dendritic Cell Activation in the Antigen-Induced Immune Responses in the Lung

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Platelet Endothelial Cell Adhesion Molecule Deficiency or Blockade Significantly Reduces Leukocyte Emigration in a Majority of Mouse Strains

Alan R. Schenkel; Tina W. Chew; William A. Muller

J Immunol (2004) 173 (10): 6403–6408.

Abstract

View articletitled, Platelet Endothelial Cell Adhesion Molecule Deficiency or Blockade Significantly Reduces Leukocyte Emigration in a Majority of Mouse Strains

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IL-5 and Granulocyte-Macrophage Colony-Stimulating Factor Activate STAT3 and STAT5 and Promote Pim-1 and Cyclin D3 Protein Expression in Human Eosinophils ¹

Barbara A. Stout; Mary Ellen Bates; Lin Ying Liu; Natasha N. Farrington; Paul J. Bertics

J Immunol (2004) 173 (10): 6409–6417.

Abstract

View articletitled, IL-5 and Granulocyte-Macrophage Colony-Stimulating Factor Activate STAT3 and STAT5 and Promote Pim-1 and Cyclin D3 Protein Expression in Human Eosinophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CD56^bright NK Cells Are Enriched at Inflammatory Sites and Can Engage with Monocytes in a Reciprocal Program of Activation ¹

Nicola Dalbeth; Roger Gundle; Robert J. O. Davies; Y. C. Gary Lee; Andrew J. McMichael; Margaret F. C. Callan

J Immunol (2004) 173 (10): 6418–6426.

Abstract

View articletitled, CD56bright NK Cells Are Enriched at Inflammatory Sites and Can Engage with Monocytes in a Reciprocal Program of Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Class A Macrophage Scavenger Receptor Attenuates CXC Chemokine Production and the Early Infiltration of Neutrophils in Sterile Peritonitis ¹

Alessia Cotena; Siamon Gordon; Nick Platt

J Immunol (2004) 173 (10): 6427–6432.

Abstract

View articletitled, The Class A Macrophage Scavenger Receptor Attenuates CXC Chemokine Production and the Early Infiltration of Neutrophils in Sterile Peritonitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Group IB Secretory Phospholipase A₂ Stimulates CXC Chemokine Ligand 8 Production via ERK and NF-κB in Human Neutrophils ¹

Eun Jin Jo; Ha-Young Lee; Youl-Nam Lee; Jung Im Kim; Hyun-Kyu Kang; Dae-Won Park; Suk-Hwan Baek; Jong-Young Kwak; Yoe-Sik Bae

J Immunol (2004) 173 (10): 6433–6439.

Abstract

View articletitled, Group IB Secretory Phospholipase A2 Stimulates CXC Chemokine Ligand 8 Production via ERK and NF-κB in Human Neutrophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Regulation of Th2 and Th1 Lung Inflammatory Responses by Protein Kinase Cθ ¹

Shahram Salek-Ardakani; Takanori So; Beth S. Halteman; Amnon Altman; Michael Croft

J Immunol (2004) 173 (10): 6440–6447.

Abstract

View articletitled, Differential Regulation of Th2 and Th1 Lung Inflammatory Responses by Protein Kinase Cθ<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Selective Basophil Chemoattractants in Human Nasal Polyps as Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-2 ¹

Adele Hartnell; Akos Heinemann; Dolores M. Conroy; Robin Wait; Gunter J. Sturm; Marco Caversaccio; Peter J. Jose; Timothy J. Williams

J Immunol (2004) 173 (10): 6448–6457.

Abstract

View articletitled, Identification of Selective Basophil Chemoattractants in Human Nasal Polyps as Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Polymorphisms in the FcεRIβ Promoter Region Affecting Transcription Activity: A Possible Promoter-Dependent Mechanism for Association between FcεRIβ and Atopy ¹

Chiharu Nishiyama; Yushiro Akizawa; Makoto Nishiyama; Tomoko Tokura; Hiroshi Kawada; Kouichi Mitsuishi; Masanari Hasegawa; Tomonobu Ito; Nobuhiro Nakano; Atsushi Okamoto; Atsushi Takagi; Hideo Yagita; Ko Okumura; Hideoki Ogawa

J Immunol (2004) 173 (10): 6458–6464.

Abstract

View articletitled, Polymorphisms in the FcεRIβ Promoter Region Affecting Transcription Activity: A Possible Promoter-Dependent Mechanism for Association between FcεRIβ and Atopy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Suppression of Ongoing Experimental Autoimmune Encephalomyelitis by Neutralizing the Function of the p28 Subunit of IL-27 ¹

Ruth Goldberg; Yaniv Zohar; Gizi Wildbaum; Yifat Geron; Gila Maor; Nathan Karin

J Immunol (2004) 173 (10): 6465–6471.

Abstract

View articletitled, Suppression of Ongoing Experimental Autoimmune Encephalomyelitis by Neutralizing the Function of the p28 Subunit of IL-27<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immune Responses of Breast Cancer Patients to Mutated Epidermal Growth Factor Receptor (EGF-RvIII, ΔEGF-R, and de2–7 EGF-R)¹

Enkhtsetseg Purev; Dewei Cai; Eric Miller; Rolf Swoboda; Ted Mayer; Andres Klein-Szanto; Francesco M. Marincola; Rosemarie Mick; Laszlo Otvos; William Wunner; Brigitte Birebent; Rajasekharan Somasundaram; Carol J. Wikstrand; Darell Bigner; Angela DeMichele; Geza Acs; Jesse A. Berlin; Dorothee Herlyn

J Immunol (2004) 173 (10): 6472–6480.

Abstract

View articletitled, Immune Responses of Breast Cancer Patients to Mutated Epidermal Growth Factor Receptor (EGF-RvIII, ΔEGF-R, and de2–7 EGF-R)<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Decreased Expression of the Ets Family Transcription Factor Fli-1 Markedly Prolongs Survival and Significantly Reduces Renal Disease in MRL/lpr Mice ¹

Xian K. Zhang; Sarah Gallant; Ivan Molano; Omar M. Moussa; Phillip Ruiz; Demetri D. Spyropoulos; Dennis K. Watson; Gary Gilkeson

J Immunol (2004) 173 (10): 6481–6489.

Abstract

View articletitled, Decreased Expression of the Ets Family Transcription Factor Fli-1 Markedly Prolongs Survival and Significantly Reduces Renal Disease in MRL/lpr Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CORRECTIONS

Evidence for Distinct Intracellular Signaling Pathways in CD34⁺ Progenitor to Dendritic Cell Differentiation from a Human Cell Line Model

Daniel C. St. Louis; Juliana B. Woodcock; Guido Fransozo; Patrick J. Blair; Louise M. Carlson; Maria Murillo; Mark R. Wells; Amanda J. Williams; Douglas S. Smoot; Sumesh Kaushal; Janelle L. Grimes; David M. Harlan; John P. Chute; Carl H. June; Ulrich Siebenlist; Kelvin P. Lee

J Immunol (2004) 173 (10): 6490.

View articletitled, Evidence for Distinct Intracellular Signaling Pathways in CD34+ Progenitor to Dendritic Cell Differentiation from a Human Cell Line Model

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Role of IFN Regulatory Factor-1 and IL-12 in Immunological Resistance to Pathogenesis of N-Methyl-N- Nitrosourea-Induced T Lymphoma

Jianguo Liu; Zhaoying Xiang; Xiaojing Ma

J Immunol (2004) 173 (10): 6490.

View articletitled, Role of IFN Regulatory Factor-1 and IL-12 in Immunological Resistance to Pathogenesis of N-Methyl-N- Nitrosourea-Induced T Lymphoma

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pH-Triggered Microparticles for Peptide Vaccination

W. Nicholas Haining; Daniel G. Anderson; Steven R. Little; Michael S. von Berwelt-Baildon; Angelo A. Cardoso; Pedro Alves; Kostas Kosmatopoulos; Lee M. Nadler; Robert Langer; Daniel S. Kohane

J Immunol (2004) 173 (10): 6490.

View articletitled, pH-Triggered Microparticles for Peptide Vaccination

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Cutting Edge: 1,25-Dihydroxyvitamin D₃ Is a Direct Inducer of Antimicrobial Peptide Gene Expression

Tian-Tian Wang; Frederick P. Nestel; Véronique Bourdeau; Yoshihiko Nagai; Qiuyu Wang; Jie Liao; Luz Tavera-Mendoza; Roberto Lin; John H. Hanrahan; Sylvie Mader; John H. White

J Immunol (2004) 173 (10): 6490.

View articletitled, Cutting Edge: 1,25-Dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene Expression

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Issues

IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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