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Issues
1 September 2004
ISSN 0022-1767
EISSN 1550-6606
PRESIDENTIAL ADDRESS
How We Can Help the Next Generation of Scientists: Introducing The “Hands-On” Primary Caregiver’s Support Program1
J Immunol (2004) 173 (5): 2891–2892.
IN THIS ISSUE
LETTERS TO THE EDITOR
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: 1,25-Dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene Expression1
Tian-Tian Wang; Frederick P. Nestel; Véronique Bourdeau; Yoshihiko Nagai; Qiuyu Wang; Jie Liao; Luz Tavera-Mendoza; Roberto Lin; John W. Hanrahan; Sylvie Mader; John H. White
J Immunol (2004) 173 (5): 2909–2912.
Cutting Edge: IL-5 Primes Th2 Cytokine-Producing Capacity in Eosinophils through a STAT5-Dependent Mechanism1
Yuechun Zhu; Luqiu Chen; Zan Huang; Serhan Alkan; Kevin D. Bunting; Renren Wen; Demin Wang; Hua Huang
J Immunol (2004) 173 (5): 2918–2922.
Cutting Edge: Regulation of CD8+ T Cell Effector Population Size1
J Immunol (2004) 173 (5): 2923–2927.
Cutting Edge: Critical Role for CD5 in Experimental Autoimmune Encephalomyelitis: Inhibition of Engagement Reverses Disease in Mice1
J Immunol (2004) 173 (5): 2928–2932.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
CD30/CD30 Ligand (CD153) Interaction Regulates CD4+ T Cell-Mediated Graft-versus-Host Disease1
Bruce R. Blazar; Robert B. Levy; Tak W. Mak; Angela Panoskaltsis-Mortari; Hiromi Muta; Monica Jones; Melinda Roskos; Jonathan S. Serody; Hideo Yagita; Eckhard R. Podack; Patricia A. Taylor
J Immunol (2004) 173 (5): 2933–2941.
CD4+CD25+ Cells Controlling a Pathogenic CD4 Response Inhibit Cytokine Differentiation, CXCR-3 Expression, and Tissue Invasion1
J Immunol (2004) 173 (5): 2942–2951.
Lymphocyte Development and Function in the Absence of Retinoic Acid-Related Orphan Receptor α1
J Immunol (2004) 173 (5): 2952–2959.
Lipid Rafts Mediate Association of LFA-1 and CD3 and Formation of the Immunological Synapse of CTL1
J Immunol (2004) 173 (5): 2960–2967.
Caspase-8 Serves Both Apoptotic and Nonapoptotic Roles1
Tae-Bong Kang; Tehila Ben-Moshe; Eugene E. Varfolomeev; Yael Pewzner-Jung; Nir Yogev; Anna Jurewicz; Ari Waisman; Ori Brenner; Rebecca Haffner; Erika Gustafsson; Parameswaran Ramakrishnan; Tsvee Lapidot; David Wallach
J Immunol (2004) 173 (5): 2976–2984.
Phosphatidylserine Regulates the Maturation of Human Dendritic Cells1
J Immunol (2004) 173 (5): 2985–2994.
A Novel Mutation in CD83 Results in the Development of a Unique Population of CD4+ T Cells
Leon F. García-Martínez; Mark W. Appleby; Karen Staehling-Hampton; Dawn M. Andrews; Yuching Chen; Mark McEuen; Phuong Tang; Rebecca L. Rhinehart; Sean Proll; Bryan Paeper; Mary E. Brunkow; Andres G. Grandea, III; Edward D. Howard; Don E. Walker; Patrick Charmley; Mechthild Jonas; Stevan Shaw; John A. Latham; Fred Ramsdell
J Immunol (2004) 173 (5): 2995–3001.
Constitutive Expression of CCR7 Directs Effector CD8 T Cells into the Splenic White Pulp and Impairs Functional Activity1
J Immunol (2004) 173 (5): 3013–3019.
Bcl-2 Transduction Protects Human Endothelial Cell Synthetic Microvessel Grafts from Allogeneic T Cells In Vivo1
J Immunol (2004) 173 (5): 3020–3026.
Vascular Endothelium Does Not Activate CD4+ Direct Allorecognition in Graft Rejection1
Daniel Kreisel; Alyssa M. Krasinskas; Alexander S. Krupnick; Andrew E. Gelman; Keki R. Balsara; Sicco H. Popma; Markus Riha; Ariella M. Rosengard; Laurence A. Turka; Bruce R. Rosengard
J Immunol (2004) 173 (5): 3027–3034.
Characterization of the Systemic Loss of Dendritic Cells in Murine Lymph Nodes During Polymicrobial Sepsis12
Philip A. Efron; Antonio Martins; Douglas Minnich; Kevin Tinsley; Ricardo Ungaro; Frances R. Bahjat; Richard Hotchkiss; Michael Clare-Salzler; Lyle L. Moldawer
J Immunol (2004) 173 (5): 3035–3043.
Opsonization with C1q and Mannose-Binding Lectin Targets Apoptotic Cells to Dendritic Cells1
Alma J. Nauta; Giuseppe Castellano; Wei Xu; Andrea M. Woltman; Maria C. Borrias; Mohamed R. Daha; Cees van Kooten; Anja Roos
J Immunol (2004) 173 (5): 3044–3050.
Identification and Characterization of pDC-Like Cells in Normal Mouse Skin and Melanomas Treated with Imiquimod1
J Immunol (2004) 173 (5): 3051–3061.
An Evaluation of Enforced Rapid Proteasomal Degradation as a Means of Enhancing Vaccine-Induced CTL Responses1
J Immunol (2004) 173 (5): 3073–3083.
Functional Maturation of CD4+CD25+CTLA4+CD45RA+ T Regulatory Cells in Human Neonatal T Cell Responses to Environmental Antigens/Allergens1
Catherine A. Thornton; John W. Upham; Matthew E. Wikström; Barbara J. Holt; Gregory P. White; Mary J. Sharp; Peter D. Sly; Patrick G. Holt
J Immunol (2004) 173 (5): 3084–3092.
p21Cip1 and p27Kip1 Act in Synergy to Alter the Sensitivity of Naive T Cells to TGF-β-Mediated G1 Arrest through Modulation of IL-2 Responsiveness
J Immunol (2004) 173 (5): 3093–3102.
Proliferation and Differentiation of CD8+ T Cells in the Absence of IL-2/15 Receptor β-Chain Expression or STAT5 Activation
J Immunol (2004) 173 (5): 3131–3139.
Functional and Genetic Analysis of Two CD8 T Cell Subsets Defined by the Level of CD45RC Expression in the Rat1
Emmanuel Xystrakis; Pierre Cavailles; Anne S. Dejean; Bastien Cautain; Céline Colacios; Dominique Lagrange; Marie-Jose van de Gaar; Isabelle Bernard; Daniel Gonzalez-Dunia; Jan Damoiseaux; Gilbert J. Fournié; Abdelhadi Saoudi
J Immunol (2004) 173 (5): 3140–3147.
IL-15Rα Is a Negative Regulator of TCR-Activated Proliferation in CD4+ T Cells1
J Immunol (2004) 173 (5): 3155–3164.
Environmental and Endogenous Peroxisome Proliferator-Activated Receptor γ Agonists Induce Bone Marrow B Cell Growth Arrest and Apoptosis: Interactions between Mono(2-ethylhexyl)phthalate, 9-cis-Retinoic Acid, and 15-Deoxy-Δ12,14-prostaglandin J21
Jennifer J. Schlezinger; Gregory J. Howard; Christopher H. Hurst; Jessica K. Emberley; David J. Waxman; Thomas Webster; David H. Sherr
J Immunol (2004) 173 (5): 3165–3177.
Fas-Mediated Inhibition of CD4+ T Cell Priming Results in Dominance of Type 1 CD8+ T Cells in the Immune Response to the Contact Sensitizer Trinitrophenyl1
Stefan F. Martin; Jan C. Dudda; Virginie Delattre; Eva Bachtanian; Cornelia Leicht; Beate Burger; Hans Ulrich Weltzien; Jan C. Simon
J Immunol (2004) 173 (5): 3178–3185.
Folate Deficiency Inhibits the Proliferation of Primary Human CD8+ T Lymphocytes In Vitro1
J Immunol (2004) 173 (5): 3186–3192.
Ceramide Inhibits IL-2 Production by Preventing Protein Kinase C-Dependent NF-κB Activation: Possible Role in Protein Kinase Cθ Regulation1
Nour Abboushi; Aimee El-Hed; Wissal El-Assaad; Lina Kozhaya; Marwan E. El-Sabban; Ali Bazarbachi; Rami Badreddine; Alicja Bielawska; Julnar Usta; Ghassan S. Dbaibo
J Immunol (2004) 173 (5): 3193–3200.
Naive T Cells Are Resistant to Anergy Induction by Anti-CD3 Antibodies1
J Immunol (2004) 173 (5): 3201–3208.
Vav-Dependent and Vav-Independent Phosphatidylinositol 3-Kinase Activation in Murine B Cells Determined by the Nature of the Stimulus1
J Immunol (2004) 173 (5): 3209–3214.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Functional Analysis of −571 IL-10 Promoter Polymorphism Reveals a Repressor Element Controlled by Sp11
J Immunol (2004) 173 (5): 3215–3222.
Single-Stranded DNA Breaks Adjacent to Cytosines Occur during Ig Gene Class Switch Recombination
J Immunol (2004) 173 (5): 3223–3229.
The Complete Map of the Ig Heavy Chain Constant Gene Region Reveals Evidence for Seven IgG Isotypes and for IgD in the Horse12
J Immunol (2004) 173 (5): 3230–3242.
The Chemoattractants, IL-8 and Formyl-Methionyl-Leucyl-Phenylalanine, Regulate Granulocyte Colony-Stimulating Factor Signaling by Inducing Suppressor of Cytokine Signaling-1 Expression1
Nigel J. Stevenson; Serge Haan; Angela E. McClurg; Michael J. McGrattan; Marilyn A. Armstrong; Peter C. Heinrich; James A. Johnston
J Immunol (2004) 173 (5): 3243–3249.
Targeted Deletion of Protein Kinase C λ Reveals a Distribution of Functions between the Two Atypical Protein Kinase C Isoforms1
J Immunol (2004) 173 (5): 3250–3260.
Rates of Recombination and Chain Pair Biases Greatly Influence the Primary γδ TCR Repertoire in the Thymus of Adult Mice1
J Immunol (2004) 173 (5): 3261–3270.
Dissecting MHC Class II Export, B Cell Maturation, and DM Stability Defects in Invariant Chain Mutant Mice1
J Immunol (2004) 173 (5): 3271–3280.
HOST DEFENSE
CCR5-Deficient Mice Control Mycobacterium tuberculosis Infection despite Increased Pulmonary Lymphocytic Infiltration1
J Immunol (2004) 173 (5): 3287–3296.
Inhibition of Lipopolysaccharide-Induced Macrophage IL-12 Production by Leishmania mexicana Amastigotes: The Role of Cysteine Peptidases and the NF-κB Signaling Pathway1
Pamela Cameron; Adrienne McGachy; Mary Anderson; Andrew Paul; Graham H. Coombs; Jeremy C. Mottram; James Alexander; Robin Plevin
J Immunol (2004) 173 (5): 3297–3304.
TGF-β Receptor Signaling Is Critical for Mucosal IgA Responses1
J Immunol (2004) 173 (5): 3305–3309.
The Cholera Toxin-Derived CTA1-DD Vaccine Adjuvant Administered Intranasally Does Not Cause Inflammation or Accumulate in the Nervous Tissues1
J Immunol (2004) 173 (5): 3310–3319.
Signaling of Apoptosis through TLRs Critically Involves Toll/IL-1 Receptor Domain-Containing Adapter Inducing IFN-β, but Not MyD88, in Bacteria-Infected Murine Macrophages1
Klaus Ruckdeschel; Gudrun Pfaffinger; Rudolf Haase; Andreas Sing; Heike Weighardt; Georg Häcker; Bernhard Holzmann; Jürgen Heesemann
J Immunol (2004) 173 (5): 3320–3328.
Coinfection Modulates Inflammatory Responses and Clinical Outcome of Helicobacter felis and Toxoplasma gondii Infections1
Calin Stoicov; Mark Whary; Arlin B. Rogers; Frederick S. Lee; Kristine Klucevsek; Hanchen Li; Xun Cai; Reza Saffari; Zhongming Ge; Imtiaz A. Khan; Crescent Combe; Andrew Luster; James G. Fox; JeanMarie Houghton
J Immunol (2004) 173 (5): 3329–3336.
Intracellularly Expressed TLR2s and TLR4s Contribution to an Immunosilent Environment at the Ocular Mucosal Epithelium1
Mayumi Ueta; Tomonori Nochi; Myoung-Ho Jang; Eun Jeong Park; Osamu Igarashi; Ayako Hino; Satoshi Kawasaki; Takashi Shikina; Takachika Hiroi; Shigeru Kinoshita; Hiroshi Kiyono
J Immunol (2004) 173 (5): 3337–3347.
Vaccine-Induced Immunity against Helicobacter pylori Infection Is Impaired in IL-18-Deficient Mice1
J Immunol (2004) 173 (5): 3348–3356.
NK Cells Use Perforin Rather than Granulysin for Anticryptococcal Activity1
Ling Ling Ma; Christopher L. C. Wang; Graham G. Neely; Slava Epelman; Alan M. Krensky; Christopher H. Mody
J Immunol (2004) 173 (5): 3357–3365.
Inhibition of the Growth of Toxoplasma gondii in Immature Human Dendritic Cells Is Dependent on the Expression of TNF-α Receptor 21
J Immunol (2004) 173 (5): 3366–3374.
A Novel Recombinant Multisubunit Vaccine against Chlamydia1
Francis O. Eko; Qing He; Teresa Brown; Lucinda McMillan; Godwin O. Ifere; Godwin A. Ananaba; Deborah Lyn; Werner Lubitz; Kathryn L. Kellar; Carolyn M. Black; Joseph U. Igietseme
J Immunol (2004) 173 (5): 3375–3382.
Prolonged Production of TNF-α Exacerbates Illness during Respiratory Syncytial Virus Infection1
J Immunol (2004) 173 (5): 3408–3417.
INFLAMMATION
Expression of a Functional C5a Receptor in Regenerating Hepatocytes and Its Involvement in a Proliferative Signaling Pathway in Rat1
Maryvonne Daveau; Magalie Benard; Michel Scotte; Marie-Therese Schouft; Martine Hiron; Arnaud Francois; Jean-Philippe Salier; Marc Fontaine
J Immunol (2004) 173 (5): 3418–3424.
Regulation of Found in Inflammatory Zone 1 Expression in Bleomycin-Induced Lung Fibrosis: Role of IL-4/IL-13 and Mediation via STAT-61
Tianju Liu; Hong Jin; Matthew Ullenbruch; Biao Hu; Naozumi Hashimoto; Bethany Moore; Andrew McKenzie; Nicholas W. Lukacs; Sem H. Phan
J Immunol (2004) 173 (5): 3425–3431.
Vitamin D Receptor-Deficient Mice Fail to Develop Experimental Allergic Asthma1
J Immunol (2004) 173 (5): 3432–3436.
C5a Initiates the Inflammatory Cascade in Immune Complex Peritonitis1
Jeanne Godau; Tanja Heller; Heiko Hawlisch; Matthew Trappe; Elaine Howells; Jennifer Best; Jörg Zwirner; J. Sjef Verbeek; P. Mark Hogarth; Craig Gerard; Nico van Rooijen; Andreas Klos; J. Engelbert Gessner; Jörg Köhl
J Immunol (2004) 173 (5): 3437–3445.
n-Nonanoyl-CC Chemokine Ligand 14, a Potent CC Chemokine Ligand 14 Analogue That Prevents the Recruitment of Eosinophils in Allergic Airway Inflammation1
Ulf Forssmann; Inka Hartung; Ralf Bälder; Barbara Fuchs; Sylvia E. Escher; Nikolaj Spodsberg; Yasmin Dulkys; Michael Walden; Aleksandra Heitland; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner
J Immunol (2004) 173 (5): 3456–3466.
Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals1
Ning Li; Jawed Alam; M. Indira Venkatesan; Arantza Eiguren-Fernandez; Debra Schmitz; Emma Di Stefano; Ndaisha Slaughter; Erin Killeen; Xiaorong Wang; Aaron Huang; Meiying Wang; Antonio H. Miguel; Arthur Cho; Constantinos Sioutas; Andre E. Nel
J Immunol (2004) 173 (5): 3467–3481.
Presence of IFN-γ Does Not Indicate Its Necessity for Induction of Coronary Arteritis in an Animal Model of Kawasaki Disease1
J Immunol (2004) 173 (5): 3492–3503.
CLINICAL IMMUNOLOGY
Short- and Long-Term Effects of IL-1 and TNF Antagonists on Periodontal Wound Healing1
J Immunol (2004) 173 (5): 3514–3523.
Mechanism of Action of Transmembrane Activator and Calcium Modulator Ligand Interactor-Ig in Murine Systemic Lupus Erythematosus1
Meera Ramanujam; Xiaobo Wang; Weiqing Huang; Lena Schiffer; Christine Grimaldi; Alla Akkerman; Betty Diamond; Michael P. Madaio; Anne Davidson
J Immunol (2004) 173 (5): 3524–3534.
Ig-Reactive CD4+CD25+ T Cells from Tolerized (New Zealand Black × New Zealand White)F1 Mice Suppress In Vitro Production of Antibodies to DNA1
J Immunol (2004) 173 (5): 3542–3548.
Frequent Joining of Bcl-2 to a JH6 Gene in Hepatitis C Virus-Associated t(14;18)1
Eric H. Sasso; Marina Martinez; Stuart L. Yarfitz; Pascale Ghillani; Lucile Musset; Jean-Charles Piette; Patrice Cacoub
J Immunol (2004) 173 (5): 3549–3556.
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