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J Immunol (2005) 174 (1): 1–2.

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PILLARS OF IMMUNOLOGY

Putting a Face to MHC Restriction

Peter Parham

J Immunol (2005) 174 (1): 3–5.

View articletitled, Putting a Face to MHC Restriction

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Pillars Article: Structure of the human class I histocompatibility antigen, HLA-A2.

P. J. Bjorkman; M. A. Saper; B. Samraoui; W. S. Bennett; J. L. Strominger; D. C. Wiley

J Immunol (2005) 174 (1): 6–12.

View articletitled, Pillars Article: Structure of the human class I histocompatibility antigen, HLA-A2.

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Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens.

P. J. Bjorkman; M. A. Saper; B. Samraoui; W. S. Bennett; J. L. Strominger; D. C. Wiley

J Immunol (2005) 174 (1): 13–19.

View articletitled, Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens.

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BRIEF REVIEWS

Cellular Interactions in Lymph Node Development

Tom Cupedo; Reina E. Mebius

J Immunol (2005) 174 (1): 21–25.

Abstract

View articletitled, Cellular Interactions in Lymph Node Development

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CUTTING EDGE

Cutting Edge: NF-κB-Activating Kinase-Associated Protein 1 Participates in TLR3/Toll-IL-1 Homology Domain-Containing Adapter Molecule-1-Mediated IFN Regulatory Factor 3 Activation ¹

Miwa Sasai; Hiroyuki Oshiumi; Misako Matsumoto; Norimitsu Inoue; Fumitaka Fujita; Makoto Nakanishi; Tsukasa Seya

J Immunol (2005) 174 (1): 27–30.

Abstract

View articletitled, Cutting Edge: NF-κB-Activating Kinase-Associated Protein 1 Participates in TLR3/Toll-IL-1 Homology Domain-Containing Adapter Molecule-1-Mediated IFN Regulatory Factor 3 Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Localization of Linker for Activation of T Cells to Lipid Rafts Is Not Essential in T Cell Activation and Development ¹

Minghua Zhu; Shudan Shen; Yan Liu; Olivia Granillo; Weiguo Zhang

J Immunol (2005) 174 (1): 31–35.

Abstract

View articletitled, Cutting Edge: Localization of Linker for Activation of T Cells to Lipid Rafts Is Not Essential in T Cell Activation and Development<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Epitope-Dependent Effect of Nef-Mediated HLA Class I Down-Regulation on Ability of HIV-1-Specific CTLs to Suppress HIV-1 Replication ¹

Hiroko Tomiyama; Mamoru Fujiwara; Shinichi Oka; Masafumi Takiguchi

J Immunol (2005) 174 (1): 36–40.

Abstract

View articletitled, Cutting Edge: Epitope-Dependent Effect of Nef-Mediated HLA Class I Down-Regulation on Ability of HIV-1-Specific CTLs to Suppress HIV-1 Replication<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Activation of CD40 in Cervical Carcinoma Cells Facilitates CTL Responses and Augments Chemotherapy-Induced Apoptosis ¹

Seran C. Hill; Sarah J. Youde; Stephen Man; Glyn R. Teale; Amanda J. Baxendale; Andrew Hislop; Clare C. Davies; David M. Luesley; Anna M. Blom; Alan B. Rickinson; Lawrence S. Young; Aristides G. Eliopoulos

J Immunol (2005) 174 (1): 41–50.

Abstract

View articletitled, Activation of CD40 in Cervical Carcinoma Cells Facilitates CTL Responses and Augments Chemotherapy-Induced Apoptosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Plexin C1 Engagement on Mouse Dendritic Cells by Viral Semaphorin A39R Induces Actin Cytoskeleton Rearrangement and Inhibits Integrin-Mediated Adhesion and Chemokine-Induced Migration

Thierry Walzer; Laurent Galibert; Michael R. Comeau; Thibaut De Smedt

J Immunol (2005) 174 (1): 51–59.

Abstract

View articletitled, Plexin C1 Engagement on Mouse Dendritic Cells by Viral Semaphorin A39R Induces Actin Cytoskeleton Rearrangement and Inhibits Integrin-Mediated Adhesion and Chemokine-Induced Migration

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Ontogeny and Regulation of IL-7-Expressing Thymic Epithelial Cells ¹

Monica Zamisch; Billie Moore-Scott; Dong-ming Su; Philip J. Lucas; Nancy Manley; Ellen R. Richie

J Immunol (2005) 174 (1): 60–67.

Abstract

View articletitled, Ontogeny and Regulation of IL-7-Expressing Thymic Epithelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distinct Calcium Channels Regulate Responses of Primary B Lymphocytes to B Cell Receptor Engagement and Mechanical Stimuli

Qing-Hua Liu; Xiaohong Liu; Zhiyun Wen; Brian Hondowicz; Leslie King; John Monroe; Bruce D. Freedman

J Immunol (2005) 174 (1): 68–79.

Abstract

View articletitled, Distinct Calcium Channels Regulate Responses of Primary B Lymphocytes to B Cell Receptor Engagement and Mechanical Stimuli

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Peptide-Specific Intercellular Transfer of MHC Class II to CD4⁺ T Cells Directly from the Immunological Synapse upon Cellular Dissociation ¹

Scott A. Wetzel; Timothy W. McKeithan; David C. Parker

J Immunol (2005) 174 (1): 80–89.

Abstract

View articletitled, Peptide-Specific Intercellular Transfer of MHC Class II to CD4+ T Cells Directly from the Immunological Synapse upon Cellular Dissociation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Supplementary data

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Dendritic Cells Loaded with Stressed Tumor Cells Elicit Long-Lasting Protective Tumor Immunity in Mice Depleted of CD4⁺CD25⁺ Regulatory T Cells ¹

Simon J. Prasad; Kathryn J. Farrand; Stephanie A. Matthews; Joe H. Chang; Rebecca S. McHugh; Franca Ronchese

J Immunol (2005) 174 (1): 90–98.

Abstract

View articletitled, Dendritic Cells Loaded with Stressed Tumor Cells Elicit Long-Lasting Protective Tumor Immunity in Mice Depleted of CD4+CD25+ Regulatory T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Type I IFN Negatively Regulates CD8⁺ T Cell Responses through IL-10-Producing CD4⁺ T Regulatory 1 Cells ¹

Nektarios Dikopoulos; Antonio Bertoletti; Andrea Kröger; Hansjörg Hauser; Reinhold Schirmbeck; Jörg Reimann

J Immunol (2005) 174 (1): 99–109.

Abstract

View articletitled, Type I IFN Negatively Regulates CD8+ T Cell Responses through IL-10-Producing CD4+ T Regulatory 1 Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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2B4 (CD244) Is Expressed and Functional on Human Eosinophils ¹

Ariel Munitz; Ido Bachelet; Shira Fraenkel; Gil Katz; Ofer Mandelboim; Hans-Uwe Simon; Lorenzo Moretta; Marco Colonna; Francesca Levi-Schaffer

J Immunol (2005) 174 (1): 110–118.

Abstract

View articletitled, 2B4 (CD244) Is Expressed and Functional on Human Eosinophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Ca²⁺ Signaling by Na⁺/Ca²⁺ Exchangers in Mast Cells

Eduardo Aneiros; Stephan Philipp; Annette Lis; Marc Freichel; Adolfo Cavalié

J Immunol (2005) 174 (1): 119–130.

Abstract

View articletitled, Modulation of Ca2+ Signaling by Na+/Ca2+ Exchangers in Mast Cells

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TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats ¹

Danny Zipris; Egil Lien; Jenny X. Xie; Dale L. Greiner; John P. Mordes; Aldo A. Rossini

J Immunol (2005) 174 (1): 131–142.

Abstract

View articletitled, TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge ¹

Neil Taylor; Karen McConnachie; Claudia Calder; Rosemary Dawson; Andrew Dick; Jonathon D. Sedgwick; Janet Liversidge

J Immunol (2005) 174 (1): 143–154.

Abstract

View articletitled, Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Uncoupling of IL-2 Signaling from Cell Cycle Progression in Naive CD4⁺ T Cells by Regulatory CD4⁺CD25⁺ T Lymphocytes ¹

Christine T. Duthoit; Divya J. Mekala; Rajshekkhar S. Alli; Terrence L. Geiger

J Immunol (2005) 174 (1): 155–163.

Abstract

View articletitled, Uncoupling of IL-2 Signaling from Cell Cycle Progression in Naive CD4+ T Cells by Regulatory CD4+CD25+ T Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dysfunctional Blood and Target Tissue CD4⁺CD25^high Regulatory T Cells in Psoriasis: Mechanism Underlying Unrestrained Pathogenic Effector T Cell Proliferation ¹

Hideaki Sugiyama; Rolland Gyulai; Eiko Toichi; Edina Garaczi; Shinji Shimada; Seth R. Stevens; Thomas S. McCormick; Kevin D. Cooper

J Immunol (2005) 174 (1): 164–173.

Abstract

View articletitled, Dysfunctional Blood and Target Tissue CD4+CD25high Regulatory T Cells in Psoriasis: Mechanism Underlying Unrestrained Pathogenic Effector T Cell Proliferation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CTLA-4 Signaling Regulates the Intensity of Hypersensitivity Responses to Food Antigens, but is Not Decisive in the Induction of Sensitization

Femke van Wijk; Sanne Hoeks; Stefan Nierkens; Stef J. Koppelman; Peter van Kooten; Louis Boon; Léon M. J. Knippels; Raymond Pieters

J Immunol (2005) 174 (1): 174–179.

Abstract

View articletitled, CTLA-4 Signaling Regulates the Intensity of Hypersensitivity Responses to Food Antigens, but is Not Decisive in the Induction of Sensitization

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CD28 Regulates the Translation of Bcl-x_L via the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Pathway ¹

Linda X. Wu; Jose La Rose; Liane Chen; Chris Neale; Tak Mak; Klaus Okkenhaug; Ronald Wange; Robert Rottapel

J Immunol (2005) 174 (1): 180–194.

Abstract

View articletitled, CD28 Regulates the Translation of Bcl-xL via the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Generation of Murine CTL by a Hepatitis B Virus-Specific Peptide and Evaluation of the Adjuvant Effect of Heat Shock Protein Glycoprotein 96 and Its Terminal Fragments ¹

Hongtao Li; Minghai Zhou; Jinle Han; Xiaodong Zhu; Tao Dong; George F. Gao; Po Tien

J Immunol (2005) 174 (1): 195–204.

Abstract

View articletitled, Generation of Murine CTL by a Hepatitis B Virus-Specific Peptide and Evaluation of the Adjuvant Effect of Heat Shock Protein Glycoprotein 96 and Its Terminal Fragments<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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BCL-6 Negatively Regulates Expression of the NF-κB1 p105/p50 Subunit ¹

Zhiping Li; Xing Wang; Raymond Yick-Loi Yu; B. Belinda Ding; J. Jessica Yu; Xu-Ming Dai; Akira Naganuma; E. Richard Stanley; B. Hilda Ye

J Immunol (2005) 174 (1): 205–214.

Abstract

View articletitled, BCL-6 Negatively Regulates Expression of the NF-κB1 p105/p50 Subunit<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Roles of Vascular Endothelial Growth Factor Receptors 1 and 2 in Dendritic Cell Differentiation ¹

Mikhail M. Dikov; Joyce E. Ohm; Neelanjan Ray; Elena E. Tchekneva; Jared Burlison; Drew Moghanaki; Sorena Nadaf; David P. Carbone

J Immunol (2005) 174 (1): 215–222.

Abstract

View articletitled, Differential Roles of Vascular Endothelial Growth Factor Receptors 1 and 2 in Dendritic Cell Differentiation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Hyperthermia Enhances CD95-Ligand Gene Expression in T Lymphocytes ¹

Marco Cippitelli; Cinzia Fionda; Danilo Di Bona; Mario Piccoli; Luigi Frati; Angela Santoni

J Immunol (2005) 174 (1): 223–232.

Abstract

View articletitled, Hyperthermia Enhances CD95-Ligand Gene Expression in T Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Immunomodulatory Effects of Novel β-Oxa, β-Thia, and γ-Thia Polyunsaturated Fatty Acids on Human T Lymphocyte Proliferation, Cytokine Production, and Activation of Protein Kinase C and MAPKs ¹

Maurizio Costabile; Charles S. T. Hii; Michelle Melino; Christopher Easton; Antonio Ferrante

J Immunol (2005) 174 (1): 233–243.

Abstract

View articletitled, The Immunomodulatory Effects of Novel β-Oxa, β-Thia, and γ-Thia Polyunsaturated Fatty Acids on Human T Lymphocyte Proliferation, Cytokine Production, and Activation of Protein Kinase C and MAPKs<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Chemokine-Like Receptor 1 Expression and Chemerin-Directed Chemotaxis Distinguish Plasmacytoid from Myeloid Dendritic Cells in Human Blood ¹

Brian A. Zabel; Amanda M. Silverio; Eugene C. Butcher

J Immunol (2005) 174 (1): 244–251.

Abstract

View articletitled, Chemokine-Like Receptor 1 Expression and Chemerin-Directed Chemotaxis Distinguish Plasmacytoid from Myeloid Dendritic Cells in Human Blood<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Reciprocal Activating Interaction Between Dendritic Cells and Pamidronate-Stimulated γδ T Cells: Role of CD86 and Inflammatory Cytokines ¹

Lucia Conti; Rita Casetti; Marco Cardone; Barbara Varano; Angelo Martino; Filippo Belardelli; Fabrizio Poccia; Sandra Gessani

J Immunol (2005) 174 (1): 252–260.

Abstract

View articletitled, Reciprocal Activating Interaction Between Dendritic Cells and Pamidronate-Stimulated γδ T Cells: Role of CD86 and Inflammatory Cytokines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-12 Protects against Coxsackievirus B3-Induced Myocarditis by Increasing IFN-γ and Macrophage and Neutrophil Populations in the Heart ¹

DeLisa Fairweather; Sylvia Frisancho-Kiss; Susy A. Yusung; Masheka A. Barrett; Sarah E. Davis; Ronelle A. Steele; Shannon J. L. Gatewood; Noel R. Rose

J Immunol (2005) 174 (1): 261–269.

Abstract

View articletitled, IL-12 Protects against Coxsackievirus B3-Induced Myocarditis by Increasing IFN-γ and Macrophage and Neutrophil Populations in the Heart<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Suppressive Effect of 1α,25-Dihydroxyvitamin D₃ on Type I IFN-Mediated Monocyte Differentiation into Dendritic Cells: Impairment of Functional Activities and Chemotaxis ¹

Maria Cristina Gauzzi; Cristina Purificato; Karim Donato; Yixin Jin; Ling Wang; Kenn C. Daniel; Azzam A. Maghazachi; Filippo Belardelli; Luciano Adorini; Sandra Gessani

J Immunol (2005) 174 (1): 270–276.

Abstract

View articletitled, Suppressive Effect of 1α,25-Dihydroxyvitamin D3 on Type I IFN-Mediated Monocyte Differentiation into Dendritic Cells: Impairment of Functional Activities and Chemotaxis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role for CXCR6 in Recruitment of Activated CD8⁺ Lymphocytes to Inflamed Liver ¹

Tohru Sato; Henrik Thorlacius; Brent Johnston; Tracy L. Staton; Wenkai Xiang; Dan R. Littman; Eugene C. Butcher

J Immunol (2005) 174 (1): 277–283.

Abstract

View articletitled, Role for CXCR6 in Recruitment of Activated CD8+ Lymphocytes to Inflamed Liver<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62 ¹

Helen S. Goodridge; Fraser A. Marshall; Kathryn J. Else; Katrina M. Houston; Caitlin Egan; Lamyaa Al-Riyami; Foo-Yew Liew; William Harnett; Margaret M. Harnett

J Immunol (2005) 174 (1): 284–293.

Abstract

View articletitled, Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-12, but Not IFN-α, Promotes STAT4 Activation and Th1 Development in Murine CD4⁺ T Cells Expressing a Chimeric Murine/Human Stat2 Gene ¹

Meredith E. Persky; Kenneth M. Murphy; J. David Farrar

J Immunol (2005) 174 (1): 294–301.

Abstract

View articletitled, IL-12, but Not IFN-α, Promotes STAT4 Activation and Th1 Development in Murine CD4+ T Cells Expressing a Chimeric Murine/Human Stat2 Gene<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Down-Regulation of Stromal Cell-Derived Factor-1α-Induced T Cell Chemotaxis by a Peptide Based on the Complementarity-Determining Region 1 of an Anti-DNA Autoantibody via Up-Regulation of TGF-β Secretion ¹

Uri Sela; Rami Hershkoviz; Liora Cahalon; Ofer Lider; Edna Mozes

J Immunol (2005) 174 (1): 302–309.

Abstract

View articletitled, Down-Regulation of Stromal Cell-Derived Factor-1α-Induced T Cell Chemotaxis by a Peptide Based on the Complementarity-Determining Region 1 of an Anti-DNA Autoantibody via Up-Regulation of TGF-β Secretion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-2 Overcomes the Unresponsiveness but Fails to Reverse the Regulatory Function of Antigen-Induced T Regulatory Cells ¹

Per O. Anderson; Anette Sundstedt; Zihni Yazici; Sophie Minaee; Richard Woolf; Kirsty Nicolson; Nathaniel Whitley; Li Li; Suling Li; David C. Wraith; Ping Wang

J Immunol (2005) 174 (1): 310–319.

Abstract

View articletitled, IL-2 Overcomes the Unresponsiveness but Fails to Reverse the Regulatory Function of Antigen-Induced T Regulatory Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

JAK-Mediated Signaling Inhibits Fas Ligand-Induced Apoptosis Independent of De Novo Protein Synthesis ¹

Leslie P. Cousens; Frederick A. Goulette; James W. Darnowski

J Immunol (2005) 174 (1): 320–327.

Abstract

View articletitled, JAK-Mediated Signaling Inhibits Fas Ligand-Induced Apoptosis Independent of De Novo Protein Synthesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Role of C-Terminal Sequence Elements in the Transporter Associated with Antigen Processing ¹

Sarah Ehses; Ralf M. Leonhardt; Guido Hansen; Michael R. Knittler

J Immunol (2005) 174 (1): 328–339.

Abstract

View articletitled, Functional Role of C-Terminal Sequence Elements in the Transporter Associated with Antigen Processing<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Functional and Structural Properties of MD-2 Required for Lipopolysaccharide Binding Are Absent in MD-1 ¹

Naoko Tsuneyoshi; Kenji Fukudome; Jun Kohara; Rika Tomimasu; Jean-Francois Gauchat; Hiroshi Nakatake; Masao Kimoto

J Immunol (2005) 174 (1): 340–344.

Abstract

View articletitled, The Functional and Structural Properties of MD-2 Required for Lipopolysaccharide Binding Are Absent in MD-1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vα and Vβ Public Repertoires Are Highly Conserved in Terminal Deoxynucleotidyl Transferase-Deficient Mice ¹

Nicolas Fazilleau; Jean-Pierre Cabaniols; Fabrice Lemaître; Iris Motta; Philippe Kourilsky; Jean M. Kanellopoulos

J Immunol (2005) 174 (1): 345–355.

Abstract

View articletitled, Vα and Vβ Public Repertoires Are Highly Conserved in Terminal Deoxynucleotidyl Transferase-Deficient Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Complement C2 Receptor Inhibitor Trispanning: A Novel Human Complement Inhibitory Receptor ¹^²

Jameel M. Inal; Kwok-Min Hui; Sylvie Miot; Sigrun Lange; Marcel Ivan Ramirez; Brigitte Schneider; Gerhard Krueger; Jürg-A. Schifferli

J Immunol (2005) 174 (1): 356–366.

Abstract

View articletitled, Complement C2 Receptor Inhibitor Trispanning: A Novel Human Complement Inhibitory Receptor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">2</a>

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Tracing the Pre-B to Immature B Cell Transition in Human Leukemia Cells Reveals a Coordinated Sequence of Primary and Secondary IGK Gene Rearrangement, IGK Deletion, and IGL Gene Rearrangement ¹

Florian Klein; Niklas Feldhahn; Jana L. Mooster; Mieke Sprangers; Wolf-Karsten Hofmann; Peter Wernet; Maria Wartenberg; Markus Müschen

J Immunol (2005) 174 (1): 367–375.

Abstract

View articletitled, Tracing the Pre-B to Immature B Cell Transition in Human Leukemia Cells Reveals a Coordinated Sequence of Primary and Secondary IGK Gene Rearrangement, IGK Deletion, and IGL Gene Rearrangement<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mast Cells Acquire Monocyte-Specific Gene Expression and Monocyte-Like Morphology by Overproduction of PU.1 ¹

Tomonobu Ito; Chiharu Nishiyama; Makoto Nishiyama; Hironori Matsuda; Keiko Maeda; Yushiro Akizawa; Ryoji Tsuboi; Ko Okumura; Hideoki Ogawa

J Immunol (2005) 174 (1): 376–383.

Abstract

View articletitled, Mast Cells Acquire Monocyte-Specific Gene Expression and Monocyte-Like Morphology by Overproduction of PU.1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Stress-Induced Inhibition of the NF-κB Signaling Pathway Results from the Insolubilization of the IκB Kinase Complex following Its Dissociation from Heat Shock Protein 90 ¹

Jean-Francois Pittet; Hyon Lee; Melissa Pespeni; Allison O’Mahony; Jeremie Roux; William J. Welch

J Immunol (2005) 174 (1): 384–394.

Abstract

View articletitled, Stress-Induced Inhibition of the NF-κB Signaling Pathway Results from the Insolubilization of the IκB Kinase Complex following Its Dissociation from Heat Shock Protein 90<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Cytokine, Chemokine, and Adhesion Molecules during Endothelial Cell Activation Induced by Antibodies against Dengue Virus Nonstructural Protein 1 ¹

Chiou-Feng Lin; Shu-Chen Chiu; Yu-Ling Hsiao; Shu-Wen Wan; Huan-Yao Lei; Ai-Li Shiau; Hsiao-Sheng Liu; Trai-Ming Yeh; Shun-Hua Chen; Ching-Chuan Liu; Yee-Shin Lin

J Immunol (2005) 174 (1): 395–403.

Abstract

View articletitled, Expression of Cytokine, Chemokine, and Adhesion Molecules during Endothelial Cell Activation Induced by Antibodies against Dengue Virus Nonstructural Protein 1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Enhancement of Dendritic Cell Production by Fms-Like Tyrosine Kinase-3 Ligand Increases the Resistance of Mice to a Burn Wound Infection ¹

Tracy E. Toliver-Kinsky; Weihua Cui; Erle D. Murphey; Chengyie Lin; Edward R. Sherwood

J Immunol (2005) 174 (1): 404–410.

Abstract

View articletitled, Enhancement of Dendritic Cell Production by Fms-Like Tyrosine Kinase-3 Ligand Increases the Resistance of Mice to a Burn Wound Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of Human Neutrophil IL-8 Production by Hydrogen Peroxide and Dysregulation in Chronic Granulomatous Disease ¹

Julie A. Lekstrom-Himes; Douglas B. Kuhns; W. Gregory Alvord; John I. Gallin

J Immunol (2005) 174 (1): 411–417.

Abstract

View articletitled, Inhibition of Human Neutrophil IL-8 Production by Hydrogen Peroxide and Dysregulation in Chronic Granulomatous Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of L-Ficolin/Mannose-Binding Lectin-Associated Serine Protease Complexes in the Opsonophagocytosis of Type III Group B Streptococci ¹

Youko Aoyagi; Elisabeth E. Adderson; Jin G. Min; Misao Matsushita; Teizo Fujita; Shinji Takahashi; Yoshiyuki Okuwaki; John F. Bohnsack

J Immunol (2005) 174 (1): 418–425.

Abstract

View articletitled, Role of L-Ficolin/Mannose-Binding Lectin-Associated Serine Protease Complexes in the Opsonophagocytosis of Type III Group B Streptococci<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Morphine Impairs Host Innate Immune Response and Increases Susceptibility to Streptococcus pneumoniae Lung Infection ¹

Jinghua Wang; Roderick A. Barke; Richard Charboneau; Sabita Roy

J Immunol (2005) 174 (1): 426–434.

Abstract

View articletitled, Morphine Impairs Host Innate Immune Response and Increases Susceptibility to Streptococcus pneumoniae Lung Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Enhanced Egg-Induced Immunopathology Correlates With High IFN-γ in Murine Schistosomiasis: Identification of Two Epistatic Genetic Intervals ¹

Laura I. Rutitzky; Hector J. Hernandez; Young-Sun Yim; David E. Ricklan; Eduardo Finger; Chandra Mohan; Inga Peter; Edward K. Wakeland; Miguel J. Stadecker

J Immunol (2005) 174 (1): 435–440.

Abstract

View articletitled, Enhanced Egg-Induced Immunopathology Correlates With High IFN-γ in Murine Schistosomiasis: Identification of Two Epistatic Genetic Intervals<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Proinflammatory Responses to Pneumocystis carinii f. sp. muris in Neonatal Mice by Granulocyte-Macrophage Colony-Stimulating Factor and IL-4: Role of APCs ¹

Mahboob H. Qureshi; Kerry M. Empey; Beth A. Garvy

J Immunol (2005) 174 (1): 441–448.

Abstract

View articletitled, Modulation of Proinflammatory Responses to Pneumocystis carinii f. sp. muris in Neonatal Mice by Granulocyte-Macrophage Colony-Stimulating Factor and IL-4: Role of APCs<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Immunogenicity of Various Heterologous Prime-Boost Vaccine Regimens Using DNA and Viral Vectors in Healthy Volunteers ¹

Jenni M. Vuola; Sheila Keating; Daniel P. Webster; Tamara Berthoud; Susanna Dunachie; Sarah C. Gilbert; Adrian V. S. Hill

J Immunol (2005) 174 (1): 449–455.

Abstract

View articletitled, Differential Immunogenicity of Various Heterologous Prime-Boost Vaccine Regimens Using DNA and Viral Vectors in Healthy Volunteers<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

In Vivo Ethanol Exposure Down-Regulates TLR2-, TLR4-, and TLR9-Mediated Macrophage Inflammatory Response by Limiting p38 and ERK1/2 Activation ¹

Joanna Goral; Elizabeth J. Kovacs

J Immunol (2005) 174 (1): 456–463.

Abstract

View articletitled, In Vivo Ethanol Exposure Down-Regulates TLR2-, TLR4-, and TLR9-Mediated Macrophage Inflammatory Response by Limiting p38 and ERK1/2 Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activation of Cytokine Production by Secreted Phospholipase A₂ in Human Lung Macrophages Expressing the M-Type Receptor ¹

Francescopaolo Granata; Angelica Petraroli; Eric Boilard; Sofiane Bezzine; James Bollinger; Luigi Del Vecchio; Michael H. Gelb; Gerard Lambeau; Gianni Marone; Massimo Triggiani

J Immunol (2005) 174 (1): 464–474.

Abstract

View articletitled, Activation of Cytokine Production by Secreted Phospholipase A2 in Human Lung Macrophages Expressing the M-Type Receptor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Hemozoin Induces Macrophage Chemokine Expression through Oxidative Stress-Dependent and -Independent Mechanisms ¹

Maritza Jaramillo; Marianne Godbout; Martin Olivier

J Immunol (2005) 174 (1): 475–484.

Abstract

View articletitled, Hemozoin Induces Macrophage Chemokine Expression through Oxidative Stress-Dependent and -Independent Mechanisms<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TNF-α Is a Critical Effector and a Target for Therapy in Antiphospholipid Antibody-Induced Pregnancy Loss ¹

Jessica Berman; Guillermina Girardi; Jane E. Salmon

J Immunol (2005) 174 (1): 485–490.

Abstract

View articletitled, TNF-α Is a Critical Effector and a Target for Therapy in Antiphospholipid Antibody-Induced Pregnancy Loss<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of Complement and Complement Membrane Attack Complex in Laser-Induced Choroidal Neovascularization ¹

Puran S. Bora; Jeong-Hyeon Sohn; Jose M. C. Cruz; Purushottam Jha; Hiroki Nishihori; Yali Wang; Sankaranarayanan Kaliappan; Henry J. Kaplan; Nalini S. Bora

J Immunol (2005) 174 (1): 491–497.

Abstract

View articletitled, Role of Complement and Complement Membrane Attack Complex in Laser-Induced Choroidal Neovascularization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Acetyl-Boswellic Acids Inhibit Lipopolysaccharide-Mediated TNF-α Induction in Monocytes by Direct Interaction with IκB Kinases ¹

Tatiana Syrovets; Berthold Büchele; Christine Krauss; Yves Laumonnier; Thomas Simmet

J Immunol (2005) 174 (1): 498–506.

Abstract

View articletitled, Acetyl-Boswellic Acids Inhibit Lipopolysaccharide-Mediated TNF-α Induction in Monocytes by Direct Interaction with IκB Kinases<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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SHIP Down-Regulates FcεR1-Induced Degranulation at Supraoptimal IgE or Antigen Levels

Kerstin Gimborn; Eva Lessmann; Stephan Kuppig; Gerald Krystal; Michael Huber

J Immunol (2005) 174 (1): 507–516.

Abstract

View articletitled, SHIP Down-Regulates FcεR1-Induced Degranulation at Supraoptimal IgE or Antigen Levels

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Macrophages Expressing Triggering Receptor Expressed on Myeloid Cells-1 Are Underrepresented in the Human Intestine ¹

Mirjam Schenk; Axel Bouchon; Stefan Birrer; Marco Colonna; Christoph Mueller

J Immunol (2005) 174 (1): 517–524.

Abstract

View articletitled, Macrophages Expressing Triggering Receptor Expressed on Myeloid Cells-1 Are Underrepresented in the Human Intestine<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cyclooxygenase Inhibition Augments Allergic Inflammation through CD4-Dependent, STAT6-Independent Mechanisms ¹

Koichi Hashimoto; James R. Sheller; Jason D. Morrow; Robert D. Collins; Kasia Goleniewska; Jamye O’Neal; Weisong Zhou; Shaoquan Ji; Daphne B. Mitchell; Barney S. Graham; R. Stokes Peebles, Jr

J Immunol (2005) 174 (1): 525–532.

Abstract

View articletitled, Cyclooxygenase Inhibition Augments Allergic Inflammation through CD4-Dependent, STAT6-Independent Mechanisms<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Genetic Interactions in Eae2 Control Collagen-Induced Arthritis and the CD4⁺/CD8⁺ T Cell Ratio ¹

Jenny Karlsson; Martina Johannesson; Therese Lindvall; Patrik Wernhoff; Rikard Holmdahl; Åsa Andersson

J Immunol (2005) 174 (1): 533–541.

Abstract

View articletitled, Genetic Interactions in Eae2 Control Collagen-Induced Arthritis and the CD4+/CD8+ T Cell Ratio<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival ¹

Andrew B. Adams; Nozomu Shirasugi; Thomas R. Jones; Megan M. Durham; Elizabeth A. Strobert; Shannon Cowan; Phyllis Rees; Rose Hendrix; Karen Price; Norma S. Kenyon; David Hagerty; Robert Townsend; Dianne Hollenbaugh; Thomas C. Pearson; Christian P. Larsen

J Immunol (2005) 174 (1): 542–550.

Abstract

View articletitled, Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Stimulation of Host NKT Cells by Synthetic Glycolipid Regulates Acute Graft-versus-Host Disease by Inducing Th2 Polarization of Donor T Cells ¹

Daigo Hashimoto; Shoji Asakura; Sachiko Miyake; Takashi Yamamura; Luc Van Kaer; Chen Liu; Mitsune Tanimoto; Takanori Teshima

J Immunol (2005) 174 (1): 551–556.

Abstract

View articletitled, Stimulation of Host NKT Cells by Synthetic Glycolipid Regulates Acute Graft-versus-Host Disease by Inducing Th2 Polarization of Donor T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Autoantibodies Modulate the T Cell Epitope Repertoire but Fail to Unmask a Pathogenic Cryptic Epitope ¹

Sonia Quaratino; Jean Ruf; Mohamed Osman; Jin Guo; Sandra McLachlan; Basil Rapoport; Marco Londei

J Immunol (2005) 174 (1): 557–563.

Abstract

View articletitled, Human Autoantibodies Modulate the T Cell Epitope Repertoire but Fail to Unmask a Pathogenic Cryptic Epitope<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

IN THIS ISSUE

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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