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Issues
15 May 2005
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
BRIEF REVIEWS
License to Heal: Bidirectional Interaction of Antigen-Specific Regulatory T Cells and Tolerogenic APC
J Immunol (2005) 174 (10): 5907–5914.
CUTTING EDGE
Cutting Edge: CD95 Maintains Effector T Cell Homeostasis in Chronic Immune Activation
Ramon Arens; Paul A. Baars; Margot Jak; Kiki Tesselaar; Martin van der Valk; Marinus H. J. van Oers; René A. W. van Lier
J Immunol (2005) 174 (10): 5915–5920.
Cutting Edge: The Acquisition of TLR Tolerance during Malaria Infection Impacts T Cell Activation 1
J Immunol (2005) 174 (10): 5921–5925.
Cutting Edge: Emergence of CD127high Functionally Competent Memory T Cells Is Compromised by High Viral Loads and Inadequate T Cell Help1
Michael J. Fuller; David A. Hildeman; Steffanie Sabbaj; Dalia E. Gaddis; Anne E. Tebo; Liang Shang; Paul A. Goepfert; Allan J. Zajac
J Immunol (2005) 174 (10): 5926–5930.
Cutting Edge: The SLAM Family Receptor Ly108 Controls T Cell and Neutrophil Functions 1
Duncan Howie; F. Stephen Laroux; Massimo Morra; Abhay R. Satoskar; Lucia E. Rosas; William A. Faubion; Aimee Julien; Svend Rietdijk; Anthony J. Coyle; Christopher Fraser; Cox Terhorst
J Immunol (2005) 174 (10): 5931–5935.
Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8+ T Cells during Primary and Secondary Viral Infections1
J Immunol (2005) 174 (10): 5936–5940.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
TGF-β1 Uses Distinct Mechanisms to Inhibit IFN-γ Expression in CD4+ T Cells at Priming and at Recall: Differential Involvement of Stat4 and T-bet1
J Immunol (2005) 174 (10): 5950–5958.
Identification of Grb2 As a Novel Binding Partner of the Signaling Lymphocytic Activation Molecule-Associated Protein Binding Receptor CD229 1
J Immunol (2005) 174 (10): 5977–5986.
TGF-β1 Inhibits Mast Cell FcεRI Expression 1
Gregorio Gomez; Carlos D. Ramirez; Juan Rivera; Manish Patel; Farnaz Norozian; Harry V. Wright; Mohit V. Kashyap; Brian O. Barnstein; Krista Fischer-Stenger; Lawrence B. Schwartz; Christopher L. Kepley; John J. Ryan
J Immunol (2005) 174 (10): 5987–5993.
IFN Regulatory Factor-2 Deficiency Revealed a Novel Checkpoint Critical for the Generation of Peripheral NK Cells 1
J Immunol (2005) 174 (10): 6005–6012.
Estrogen Regulates CCR Gene Expression and Function in T Lymphocytes 1
RuRan Mo; Jun Chen; Annabelle Grolleau-Julius; Hedwig S. Murphy; Bruce C. Richardson; Raymond L. Yung
J Immunol (2005) 174 (10): 6023–6029.
Cyclophilin A-Deficient Mice Are Resistant to Immunosuppression by Cyclosporine1
J Immunol (2005) 174 (10): 6030–6038.
Spontaneous and Homeostatic Proliferation of CD4 T Cells Are Regulated by Different Mechanisms
J Immunol (2005) 174 (10): 6039–6044.
γδ T Cells Respond Directly to Pathogen-Associated Molecular Patterns 12
J Immunol (2005) 174 (10): 6045–6053.
Selective Expression of the 21-Kilodalton Tyrosine-Phosphorylated Form of TCR ζ Promotes the Emergence of T Cells with Autoreactive Potential 1
Lisa A. Pitcher; Meredith A. Mathis; Srividya Subramanian; Jennifer A. Young; Edward K. Wakeland; Paul E. Love; Nicolai S. C. van Oers
J Immunol (2005) 174 (10): 6071–6079.
Reactive Oxygen Species and 12/15-Lipoxygenase Contribute to the Antiproliferative Capacity of Alternatively Activated Myeloid Cells Elicited during Helminth Infection 1
Lea Brys; Alain Beschin; Geert Raes; Gholamreza Hassanzadeh Ghassabeh; Wim Noël; Jef Brandt; Frank Brombacher; Patrick De Baetselier
J Immunol (2005) 174 (10): 6095–6104.
Tid1 Is Required for T Cell Transition from Double-Negative 3 to Double-Positive Stages 1
J Immunol (2005) 174 (10): 6105–6112.
CpG-Independent Synergistic Induction of β-Chemokines and a Dendritic Cell Phenotype by Orthophosphorothioate Oligodeoxynucleotides and Granulocyte-Macrophage Colony-Stimulating Factor in Elutriated Human Primary Monocytes1
Jinhai Wang; Raymond Alvarez; Gregory Roderiquez; Ennan Guan; Quincy Caldwell; Jiun Wang; Michael Phelan; Michael A. Norcross
J Immunol (2005) 174 (10): 6113–6121.
Impaired TGF-β Responses in Peripheral T Cells of Gαi2−/− Mice 1
J Immunol (2005) 174 (10): 6122–6128.
TGF-α Regulates TLR Expression and Function on Epidermal Keratinocytes1
Lloyd S. Miller; Ole E. Sørensen; Philip T. Liu; H. Ray Jalian; Deborah Eshtiaghpour; Behnaz E. Behmanesh; Woosin Chung; Timothy D. Starner; Jenny Kim; Peter A. Sieling; Tomas Ganz; Robert L. Modlin
J Immunol (2005) 174 (10): 6137–6143.
Transcriptional Profiling of γδ T Cells Identifies a Role for Vitamin D in the Immunoregulation of the Vγ9Vδ2 Response to Phosphate-Containing Ligands1
Lanfen Chen; Maria Teresa Cencioni; Daniela F. Angelini; Giovanna Borsellino; Luca Battistini; Celia F. Brosnan
J Immunol (2005) 174 (10): 6144–6152.
An Ancient Role for a Prokineticin Domain in Invertebrate Hematopoiesis 1
J Immunol (2005) 174 (10): 6153–6160.
TGF-β Inhibits Fas-Mediated Apoptosis of a Follicular Dendritic Cell Line by Down-Regulating the Expression of Fas and Caspase-8: Counteracting Role of TGF-β on TNF Sensitization of Fas-Mediated Apoptosis 1
Sun-Mi Park; Sunshin Kim; Jin-Suk Choi; Dae-Young Hur; Wang-Jae Lee; Myung-Shik Lee; Jongseon Choe; Tae H. Lee
J Immunol (2005) 174 (10): 6169–6175.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Enforced Expression of Spi-B Reverses T Lineage Commitment and Blocks β-Selection 1
Juliette M. Lefebvre; Mariëlle C. Haks; Michael O. Carleton; Michele Rhodes; Gomathinayagam Sinnathamby; M. Celeste Simon; Laurence C. Eisenlohr; Lee Ann Garrett-Sinha; David L. Wiest
J Immunol (2005) 174 (10): 6184–6194.
Mechanisms of Dimethyl Sulfoxide Augmentation of IL-1β Production 1
J Immunol (2005) 174 (10): 6195–6202.
Demethylation of the Same Promoter Sequence Increases CD70 Expression in Lupus T Cells and T Cells Treated with Lupus-Inducing Drugs1
J Immunol (2005) 174 (10): 6212–6219.
Beyond the 12/23 Rule of VDJ Recombination Independent of the Rag Proteins 1
J Immunol (2005) 174 (10): 6220–6226.
Recombinant C345C and Factor I Modules of Complement Components C5 and C7 Inhibit C7 Incorporation into the Complement Membrane Attack Complex 1
J Immunol (2005) 174 (10): 6227–6232.
Transcriptional Regulation of the Human CD3γ Gene: The TATA-Less CD3γ Promoter Functions via an Initiator and Contiguous Sp-Binding Elements 1
Bassam M. Badran; Kevin Kunstman; Jennifer Stanton; Maria Moschitta; Anne Zerghe; Haidar Akl; Arsène Burny; Steven M. Wolinsky; Karen E. Willard-Gallo
J Immunol (2005) 174 (10): 6238–6249.
Human Factor H-Related Protein 5 Has Cofactor Activity, Inhibits C3 Convertase Activity, Binds Heparin and C-Reactive Protein, and Associates with Lipoprotein 1
Jennifer L. McRae; Thomas G. Duthy; Kim M. Griggs; Rebecca J. Ormsby; Peter J. Cowan; Brett A. Cromer; William J. McKinstry; Michael W. Parker; Brendan F. Murphy; David L. Gordon
J Immunol (2005) 174 (10): 6250–6256.
HOST DEFENSE
Protective Immunity to Genital Herpes Simpex Virus Type 2 Infection Is Mediated by T-bet 1
J Immunol (2005) 174 (10): 6266–6273.
Analysis of the 5q31-q33 Locus Shows an Association between IL13-1055C/T IL-13-591A/G Polymorphisms and Schistosoma haematobium Infections 1
Bourema Kouriba; Christophe Chevillard; Jay H. Bream; Laurent Argiro; Helia Dessein; Violaine Arnaud; Lansana Sangare; Abdoulaye Dabo; Abdou Habib Beavogui; Charles Arama; Hamar A. Traoré; Ogobara Doumbo; Alain Dessein
J Immunol (2005) 174 (10): 6274–6281.
Dendritic Cells Cross-Present Exogenous Fungal Antigens to Stimulate a Protective CD8 T Cell Response in Infection by Histoplasma capsulatum1
J Immunol (2005) 174 (10): 6282–6291.
Electroporation as a “Prime/Boost” Strategy for Naked DNA Vaccination against a Tumor Antigen1
J Immunol (2005) 174 (10): 6292–6298.
Binding of the Complement Inhibitor C4bp to Serogroup B Neisseria meningitidis 1
J Immunol (2005) 174 (10): 6299–6307.
The Mucosal Adjuvant Macrophage-Activating Lipopeptide-2 Directly Stimulates B Lymphocytes via the TLR2 without the Need of Accessory Cells 1
Stefan Borsutzky; Karsten Kretschmer; Pablo D. Becker; Peter F. Mühlradt; Carsten J. Kirschning; Siegfried Weiss; Carlos A. Guzmán
J Immunol (2005) 174 (10): 6308–6313.
Caspase-8 Activity Prevents Type 2 Cytokine Responses and Is Required for Protective T Cell-Mediated Immunity against Trypanosoma cruzi Infection 1
Elisabeth M. Silva; Landi V. C. Guillermo; Flávia L. Ribeiro-Gomes; Juliana De Meis; Renata M. S. Pereira; Zhengqi Wu; Teresa C. Calegari-Silva; Sérgio H. Seabra; Ulisses G. Lopes; Richard M. Siegel; George A. DosReis; Marcela F. Lopes
J Immunol (2005) 174 (10): 6314–6321.
Exchanging ESAT6 with TB10.4 in an Ag85B Fusion Molecule-Based Tuberculosis Subunit Vaccine: Efficient Protection and ESAT6-Based Sensitive Monitoring of Vaccine Efficacy 1
Jes Dietrich; Claus Aagaard; Robert Leah; Anja W. Olsen; Anette Stryhn; T. Mark Doherty; Peter Andersen
J Immunol (2005) 174 (10): 6332–6339.
Insights into Pathogen Immune Evasion Mechanisms: Anaplasma phagocytophilum Fails to Induce an Apoptosis Differentiation Program in Human Neutrophils 1
Dori L. Borjesson; Scott D. Kobayashi; Adeline R. Whitney; Jovanka M. Voyich; Cynthia M. Argue; Frank R. DeLeo
J Immunol (2005) 174 (10): 6364–6372.
INFLAMMATION
Estradiol Is Required for a Proper Immune Response to Bacterial and Viral Pathogens in the Female Brain 1
J Immunol (2005) 174 (10): 6391–6398.
A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease 1
Madeline M. Fort; Afsaneh Mozaffarian; Axel G. Stöver; Jean da Silva Correia; David A. Johnson; R. Thomas Crane; Richard J. Ulevitch; David H. Persing; Helle Bielefeldt-Ohmann; Peter Probst; Eric Jeffery; Steven P. Fling; Robert M. Hershberg
J Immunol (2005) 174 (10): 6416–6423.
Regulation of c-Jun Phosphorylation by the IκB Kinase-ε Complex in Fibroblast-Like Synoviocytes1
J Immunol (2005) 174 (10): 6424–6430.
Exosomes Derived from IL-10-Treated Dendritic Cells Can Suppress Inflammation and Collagen-Induced Arthritis 1
Seon-Hee Kim; Eric R. Lechman; Nicole Bianco; Rajasree Menon; Annahita Keravala; Joan Nash; Zhibao Mi; Simon C. Watkins; Andrea Gambotto; Paul D. Robbins
J Immunol (2005) 174 (10): 6440–6448.
Role of Lipoteichoic Acid in the Phagocyte Response to Group B Streptococcus1
Philipp Henneke; Siegfried Morath; Satoshi Uematsu; Stefan Weichert; Markus Pfitzenmaier; Osamu Takeuchi; Andrea Müller; Claire Poyart; Shizuo Akira; Reinhard Berner; Giuseppe Teti; Armin Geyer; Thomas Hartung; Patrick Trieu-Cuot; Dennis L. Kasper; Douglas T. Golenbock
J Immunol (2005) 174 (10): 6449–6455.
A Critical Role for Sphingosine Kinase in Anaphylatoxin-Induced Neutropenia, Peritonitis, and Cytokine Production in Vivo 1
J Immunol (2005) 174 (10): 6456–6461.
A Direct Role for C1 Inhibitor in Regulation of Leukocyte Adhesion 1
Shenghe Cai; Vandana S. Dole; Wolfgang Bergmeier; Jennifer Scafidi; Hanping Feng; Denisa D. Wagner; Alvin E. Davis, III
J Immunol (2005) 174 (10): 6462–6466.
TLR4, but Not TLR2, Signals Autoregulatory Apoptosis of Cultured Microglia: A Critical Role of IFN-β as a Decision Maker 1
J Immunol (2005) 174 (10): 6467–6476.
CLINICAL IMMUNOLOGY
Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2Rγnull Mice Engrafted with Mobilized Human Hemopoietic Stem Cells 12
Leonard D. Shultz; Bonnie L. Lyons; Lisa M. Burzenski; Bruce Gott; Xiaohua Chen; Stanley Chaleff; Malak Kotb; Stephen D. Gillies; Marie King; Julie Mangada; Dale L. Greiner; Rupert Handgretinger
J Immunol (2005) 174 (10): 6477–6489.
Activation of Discoidin Domain Receptor 1 on CD14-Positive Bronchoalveolar Lavage Fluid Cells Induces Chemokine Production in Idiopathic Pulmonary Fibrosis 1
Wataru Matsuyama; Masaki Watanabe; Yuko Shirahama; Ken-ichi Oonakahara; Ikkou Higashimoto; Teizo Yoshimura; Mitsuhiro Osame; Kimiyoshi Arimura
J Immunol (2005) 174 (10): 6490–6498.
Human 60-kDa Heat Shock Protein Is a Target Autoantigen of T Cells Derived from Atherosclerotic Plaques 1
Marisa Benagiano; Mario M. D’Elios; Amedeo Amedei; Annalisa Azzurri; Ruurd van der Zee; Alessandra Ciervo; Gianni Rombolà; Sergio Romagnani; Antonio Cassone; Gianfranco Del Prete
J Immunol (2005) 174 (10): 6509–6517.
Nucleotide-Binding Oligomerization Domain-2 Modulates Specific TLR Pathways for the Induction of Cytokine Release 1
Mihai G. Netea; Gerben Ferwerda; Dirk J. de Jong; Trees Jansen; Liesbeth Jacobs; Matthijs Kramer; Ton H. J. Naber; Joost P. H. Drenth; Stephen E. Girardin; Bart Jan Kullberg; Gosse J. Adema; Jos W. M. Van der Meer
J Immunol (2005) 174 (10): 6518–6523.
Gene Transfer of Tissue Inhibitor of Metalloproteinases-3 Reverses the Inhibitory Effects of TNF-α on Fas-Induced Apoptosis in Rheumatoid Arthritis Synovial Fibroblasts1
Andreas Drynda; Paul H. A. Quax; Manfred Neumann; Willemijn H. van der Laan; Géza Pap; Susanne Drynda; Ingmar Meinecke; Joern Kekow; Wolfram Neumann; Tom W. J. Huizinga; Michael Naumann; Wolfgang König; Thomas Pap
J Immunol (2005) 174 (10): 6524–6531.
Hepatitis C Virus Drives the Unconstrained Monoclonal Expansion of VH1–69-Expressing Memory B Cells in Type II Cryoglobulinemia: A Model of Infection-Driven Lymphomagenesis 1
Maurizio Carbonari; Elisabetta Caprini; Tiziana Tedesco; Francesca Mazzetta; Valeria Tocco; Milvia Casato; Giandomenico Russo; Massimo Fiorilli
J Immunol (2005) 174 (10): 6532–6539.
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