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J Immunol (2005) 174 (2): 587–588.

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BRIEF REVIEWS

Leukotrienes: Underappreciated Mediators of Innate Immune Responses ¹

Marc Peters-Golden; Claudio Canetti; Peter Mancuso; Michael J. Coffey

J Immunol (2005) 174 (2): 589–594.

Abstract

View articletitled, Leukotrienes: Underappreciated Mediators of Innate Immune Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CUTTING EDGE

Cutting Edge: Macrophage Inhibition by Cyclic AMP (cAMP): Differential Roles of Protein Kinase A and Exchange Protein Directly Activated by cAMP-1 ¹

David M. Aronoff; Claudio Canetti; Carlos H. Serezani; Ming Luo; Marc Peters-Golden

J Immunol (2005) 174 (2): 595–599.

Abstract

View articletitled, Cutting Edge: Macrophage Inhibition by Cyclic AMP (cAMP): Differential Roles of Protein Kinase A and Exchange Protein Directly Activated by cAMP-1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Bcl-3 Up-Regulation by Signal 3 Cytokine (IL-12) Prolongs Survival of Antigen-Activated CD8 T Cells ¹

Javier O. Valenzuela; Christopher D. Hammerbeck; Matthew F. Mescher

J Immunol (2005) 174 (2): 600–604.

Abstract

View articletitled, Cutting Edge: Bcl-3 Up-Regulation by Signal 3 Cytokine (IL-12) Prolongs Survival of Antigen-Activated CD8 T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Species-Specific TLR9-Mediated Recognition of CpG and Non-CpG Phosphorothioate-Modified Oligonucleotides ¹

Tara L. Roberts; Matthew J. Sweet; David A. Hume; Katryn J. Stacey

J Immunol (2005) 174 (2): 605–608.

Abstract

View articletitled, Cutting Edge: Species-Specific TLR9-Mediated Recognition of CpG and Non-CpG Phosphorothioate-Modified Oligonucleotides<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Role of STAT1, STAT3, and STAT5 in IFN-αβ Responses in T Lymphocytes

Yoshinari Tanabe; Takeaki Nishibori; Leon Su; Robert M. Arduini; Darren P. Baker; Michael David

J Immunol (2005) 174 (2): 609–613.

Abstract

View articletitled, Cutting Edge: Role of STAT1, STAT3, and STAT5 in IFN-αβ Responses in T Lymphocytes

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Cutting Edge: MHC Class II-Restricted Killing In Vivo during Viral Infection ¹

Evan R. Jellison; Sung-Kwon Kim; Raymond M. Welsh

J Immunol (2005) 174 (2): 614–618.

Abstract

View articletitled, Cutting Edge: MHC Class II-Restricted Killing In Vivo during Viral Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Peripheral “CD8 Tuning” Dynamically Modulates the Size and Responsiveness of an Antigen-Specific T Cell Pool In Vivo ¹

Robert Maile; Catherine A. Siler; Samantha E. Kerry; Katherine E. Midkiff; Edward J. Collins; Jeffrey A. Frelinger

J Immunol (2005) 174 (2): 619–627.

Abstract

View articletitled, Peripheral “CD8 Tuning” Dynamically Modulates the Size and Responsiveness of an Antigen-Specific T Cell Pool In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Heterogeneity of Expression of IgA Receptors by Human, Mouse, and Rat Eosinophils ¹

Véronique Decot; Gaëtane Woerly; Marc Loyens; Sylvie Loiseau; Brigitte Quatannens; Monique Capron; David Dombrowicz

J Immunol (2005) 174 (2): 628–635.

Abstract

View articletitled, Heterogeneity of Expression of IgA Receptors by Human, Mouse, and Rat Eosinophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease ¹

Pratima Sinha; Virginia K. Clements; Suzanne Ostrand-Rosenberg

J Immunol (2005) 174 (2): 636–645.

Abstract

View articletitled, Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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LIGHT Is Constitutively Expressed on T and NK Cells in the Human Gut and Can Be Induced by CD2-Mediated Signaling ¹

Offer Cohavy; Jaclyn Zhou; Carl F. Ware; Stephan R. Targan

J Immunol (2005) 174 (2): 646–653.

Abstract

View articletitled, LIGHT Is Constitutively Expressed on T and NK Cells in the Human Gut and Can Be Induced by CD2-Mediated Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Autocrine Regulation of T Cell Motility by Calreticulin-Thrombospondin-1 Interaction ¹

Shu Shun Li; Anna Forslöw; Karl-Gösta Sundqvist

J Immunol (2005) 174 (2): 654–661.

Abstract

View articletitled, Autocrine Regulation of T Cell Motility by Calreticulin-Thrombospondin-1 Interaction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-10 Diminishes CTLA-4 Expression on Islet-Resident T Cells and Sustains Their Activation Rather Than Tolerance ¹

Randal K. Gregg; J. Jeremiah Bell; Hyun-Hee Lee; Renu Jain; Scott J. Schoenleber; Rohit Divekar; Habib Zaghouani

J Immunol (2005) 174 (2): 662–670.

Abstract

View articletitled, IL-10 Diminishes CTLA-4 Expression on Islet-Resident T Cells and Sustains Their Activation Rather Than Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phagocytosis-Induced Apoptosis in Macrophages Is Mediated by Up-Regulation and Activation of the Bcl-2 Homology Domain 3-Only Protein Bim ¹

Susanne Kirschnek; Songmin Ying; Silke F. Fischer; Hans Häcker; Andreas Villunger; Hubertus Hochrein; Georg Häcker

J Immunol (2005) 174 (2): 671–679.

Abstract

View articletitled, Phagocytosis-Induced Apoptosis in Macrophages Is Mediated by Up-Regulation and Activation of the Bcl-2 Homology Domain 3-Only Protein Bim<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dysregulated B7-1 and B7-2 Expression on Nonobese Diabetic Mouse B Cells Is Associated with Increased T Cell Costimulation and the Development of Insulitis ¹

Shabbir Hussain; Terry L. Delovitch

J Immunol (2005) 174 (2): 680–687.

Abstract

View articletitled, Dysregulated B7-1 and B7-2 Expression on Nonobese Diabetic Mouse B Cells Is Associated with Increased T Cell Costimulation and the Development of Insulitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Negative Regulation of T Cell Homeostasis by Lymphocyte Activation Gene-3 (CD223)¹

Creg J. Workman; Dario A. A. Vignali

J Immunol (2005) 174 (2): 688–695.

Abstract

View articletitled, Negative Regulation of T Cell Homeostasis by Lymphocyte Activation Gene-3 (CD223)<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vaccination with an Acidic Polymerase Epitope of Influenza Virus Elicits a Potent Antiviral T Cell Response but Delayed Clearance of an Influenza Virus Challenge ¹

Sherry R. Crowe; Shannon C. Miller; Rachael M. Shenyo; David L. Woodland

J Immunol (2005) 174 (2): 696–701.

Abstract

View articletitled, Vaccination with an Acidic Polymerase Epitope of Influenza Virus Elicits a Potent Antiviral T Cell Response but Delayed Clearance of an Influenza Virus Challenge<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Activation of Anti-Erythrocyte and Anti-DNA Autoreactive B Lymphocytes by the Yaa Mutation ¹

Thomas Moll; Eduardo Martinez-Soria; Marie-Laure Santiago-Raber; Hirofumi Amano; Maria Pihlgren-Bosch; Dragan Marinkovic; Shozo Izui

J Immunol (2005) 174 (2): 702–709.

Abstract

View articletitled, Differential Activation of Anti-Erythrocyte and Anti-DNA Autoreactive B Lymphocytes by the Yaa Mutation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of CD70 on Dendritic Cells through CD40 or TLR Stimulation Contributes to the Development of CD8⁺ T Cell Responses in the Absence of CD4⁺ T Cells ¹

Timothy N. J. Bullock; Hideo Yagita

J Immunol (2005) 174 (2): 710–717.

Abstract

View articletitled, Induction of CD70 on Dendritic Cells through CD40 or TLR Stimulation Contributes to the Development of CD8+ T Cell Responses in the Absence of CD4+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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T Cells Undergo Rapid ON/OFF but Not ON/OFF/ON Cycling of Cytokine Production in Response to Antigen ¹

Gail A. Corbin; John T. Harty

J Immunol (2005) 174 (2): 718–726.

Abstract

View articletitled, T Cells Undergo Rapid ON/OFF but Not ON/OFF/ON Cycling of Cytokine Production in Response to Antigen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Reciprocal Interaction of NK Cells with Plasmacytoid or Myeloid Dendritic Cells Profoundly Affects Innate Resistance Functions ¹

Franca Gerosa; Andrea Gobbi; Penelope Zorzi; Stephanie Burg; Francine Briere; Giuseppe Carra; Giorgio Trinchieri

J Immunol (2005) 174 (2): 727–734.

Abstract

View articletitled, The Reciprocal Interaction of NK Cells with Plasmacytoid or Myeloid Dendritic Cells Profoundly Affects Innate Resistance Functions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Antigen-Capturing Cells as Basophils ¹

Matthias Mack; Martin A. Schneider; Cordula Moll; Josef Cihak; Hilke Brühl; Joachim W. Ellwart; Mark P. Hogarth; Manfred Stangassinger; Detlef Schlöndorff

J Immunol (2005) 174 (2): 735–741.

Abstract

View articletitled, Identification of Antigen-Capturing Cells as Basophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TLR Ligands Can Activate Dendritic Cells to Provide a MyD88-Dependent Negative Signal for Th2 Cell Development ¹

Jie Sun; Matthew Walsh; Alejandro V. Villarino; Laura Cervi; Christopher A. Hunter; Yongwon Choi; Edward J. Pearce

J Immunol (2005) 174 (2): 742–751.

Abstract

View articletitled, TLR Ligands Can Activate Dendritic Cells to Provide a MyD88-Dependent Negative Signal for Th2 Cell Development<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-γ Negatively Modulates Self-Renewal of Repopulating Human Hemopoietic Stem Cells ¹

Liping Yang; Ingunn Dybedal; David Bryder; Lars Nilsson; Ewa Sitnicka; Yutaka Sasaki; Sten Eirik W. Jacobsen

J Immunol (2005) 174 (2): 752–757.

Abstract

View articletitled, IFN-γ Negatively Modulates Self-Renewal of Repopulating Human Hemopoietic Stem Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Langerhans Cells Derived from Genetically Modified Human CD34⁺ Hemopoietic Progenitors Are More Potent Than Peptide-Pulsed Langerhans Cells for Inducing Antigen-Specific CD8⁺ Cytolytic T Lymphocyte Responses ¹

Jianda Yuan; Jean-Baptiste Latouche; John L. Reagan; Glenn Heller; Isabelle Riviere; Michel Sadelain; James W. Young

J Immunol (2005) 174 (2): 758–766.

Abstract

View articletitled, Langerhans Cells Derived from Genetically Modified Human CD34+ Hemopoietic Progenitors Are More Potent Than Peptide-Pulsed Langerhans Cells for Inducing Antigen-Specific CD8+ Cytolytic T Lymphocyte Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dendritic Cells and NK Cells Stimulate Bystander T Cell Activation in Response to TLR Agonists through Secretion of IFN-αβ and IFN-γ ¹

Arun T. Kamath; Christopher E. Sheasby; David F. Tough

J Immunol (2005) 174 (2): 767–776.

Abstract

View articletitled, Dendritic Cells and NK Cells Stimulate Bystander T Cell Activation in Response to TLR Agonists through Secretion of IFN-αβ and IFN-γ<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CpG Oligodeoxynucleotides Enhance Neonatal Resistance to Listeria Infection

Shuichi Ito; Ken J. Ishii; Mayda Gursel; Hidekazu Shirotra; Atsushi Ihata; Dennis M. Klinman

J Immunol (2005) 174 (2): 777–782.

Abstract

View articletitled, CpG Oligodeoxynucleotides Enhance Neonatal Resistance to Listeria Infection

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Pharmacological Targeting of Anaphylatoxin Receptors during the Effector Phase of Allergic Asthma Suppresses Airway Hyperresponsiveness and Airway Inflammation ¹

Ralf Baelder; Barbara Fuchs; Wilfried Bautsch; Joerg Zwirner; Jörg Köhl; Heinz G Hoymann; Thomas Glaab; Veit Erpenbeck; Norbert Krug; Armin Braun

J Immunol (2005) 174 (2): 783–789.

Abstract

View articletitled, Pharmacological Targeting of Anaphylatoxin Receptors during the Effector Phase of Allergic Asthma Suppresses Airway Hyperresponsiveness and Airway Inflammation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of CD28 in Polyclonal and Specific T and B Cell Responses Required for Protection against Blood Stage Malaria ¹

Rosa M. Elias; Luiz R. Sardinha; Karina R. B. Bastos; Cláudia A. Zago; Ana Paula Freitas da Silva; José M. Alvarez; Maria Regina D’Império Lima

J Immunol (2005) 174 (2): 790–799.

Abstract

View articletitled, Role of CD28 in Polyclonal and Specific T and B Cell Responses Required for Protection against Blood Stage Malaria<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Targeted Disruption of the 2B4 Gene in Mice Reveals an In Vivo Role of 2B4 (CD244) in the Rejection of B16 Melanoma Cells ¹

Swapnil V. Vaidya; Susan E. Stepp; Megan E. McNerney; Jae-Kyung Lee; Michael Bennett; Kyung-Mi Lee; Colin L. Stewart; Vinay Kumar; Porunelloor A. Mathew

J Immunol (2005) 174 (2): 800–807.

Abstract

View articletitled, Targeted Disruption of the 2B4 Gene in Mice Reveals an In Vivo Role of 2B4 (CD244) in the Rejection of B16 Melanoma Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Proinflammatory Bacterial Peptidoglycan as a Cofactor for the Development of Central Nervous System Autoimmune Disease

Lizette Visser; Hendrik Jan de Heer; Leonie A. Boven; Debby van Riel; Marjan van Meurs; Marie-José Melief; Ulrich Zähringer; Jos van Strijp; Bart N. Lambrecht; Edward E. Nieuwenhuis; Jon D. Laman

J Immunol (2005) 174 (2): 808–816.

Abstract

View articletitled, Proinflammatory Bacterial Peptidoglycan as a Cofactor for the Development of Central Nervous System Autoimmune Disease

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Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy ¹

J Immunol (2005) 174 (2): 817–826.

Abstract

View articletitled, Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Uncoupling of Anergy from Developmental Arrest in Anti-Insulin B Cells Supports the Development of Autoimmune Diabetes ¹

Carlos A. Acevedo-Suárez; Chrys Hulbert; Emily J. Woodward; James W. Thomas

J Immunol (2005) 174 (2): 827–833.

Abstract

View articletitled, Uncoupling of Anergy from Developmental Arrest in Anti-Insulin B Cells Supports the Development of Autoimmune Diabetes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Transcriptional Profiling Reveals Complex Regulation of the Monocyte IL-1β System by IL-13 ¹

Chris J. Scotton; Fernando O. Martinez; Maaike J. Smelt; Marina Sironi; Massimo Locati; Alberto Mantovani; Silvano Sozzani

J Immunol (2005) 174 (2): 834–845.

Abstract

View articletitled, Transcriptional Profiling Reveals Complex Regulation of the Monocyte IL-1β System by IL-13<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Matrix Metalloproteinase-9 in Macrophages Induces Thymic Neovascularization following Thymocyte Apoptosis

Chikako Odaka; Masatoshi Tanioka; Takeshi Itoh

J Immunol (2005) 174 (2): 846–853.

Abstract

View articletitled, Matrix Metalloproteinase-9 in Macrophages Induces Thymic Neovascularization following Thymocyte Apoptosis

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Dynamics of Dendritic Cell Phenotype and Interactions with CD4⁺ T Cells in Airway Inflammation and Tolerance ¹

Timothy B. Oriss; Marina Ostroukhova; Carole Seguin-Devaux; Barbara Dixon-McCarthy; Donna B. Stolz; Simon C. Watkins; Brendan Pillemer; Prabir Ray; Anuradha Ray

J Immunol (2005) 174 (2): 854–863.

Abstract

View articletitled, Dynamics of Dendritic Cell Phenotype and Interactions with CD4+ T Cells in Airway Inflammation and Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines ¹

Junko Ohata; Nathan J. Zvaifler; Mitsufumi Nishio; David L. Boyle; Susan L. Kalled; Dennis A. Carson; Thomas J. Kipps

J Immunol (2005) 174 (2): 864–870.

Abstract

View articletitled, Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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p53 Potentiation of Tumor Cell Susceptibility to CTL Involves Fas and Mitochondrial Pathways ¹

Jérôme Thiery; Soraya Abouzahr; Guillaume Dorothee; Abdelali Jalil; Catherine Richon; Isabelle Vergnon; Fathia Mami-Chouaib; Salem Chouaib

J Immunol (2005) 174 (2): 871–878.

Abstract

View articletitled, p53 Potentiation of Tumor Cell Susceptibility to CTL Involves Fas and Mitochondrial Pathways<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Expression of 11β-Hydroxysteroid Dehydrogenase Type I by Lymphocytes Provides a Novel Means for Intracrine Regulation of Glucocorticoid Activities ¹

Tian Y. Zhang; Xiaohong Ding; Raymond A. Daynes

J Immunol (2005) 174 (2): 879–889.

Abstract

View articletitled, The Expression of 11β-Hydroxysteroid Dehydrogenase Type I by Lymphocytes Provides a Novel Means for Intracrine Regulation of Glucocorticoid Activities<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Notch Regulator Numb Links the Notch and TCR Signaling Pathways ¹

Ana C. Anderson; Elizabeth A. Kitchens; Shiao Wei Chan; Charles St. Hill; Yuh Nung Jan; Weimin Zhong; Ellen A. Robey

J Immunol (2005) 174 (2): 890–897.

Abstract

View articletitled, The Notch Regulator Numb Links the Notch and TCR Signaling Pathways<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human CD4⁺ Effector Memory T Cells Persisting in the Microenvironment of Lung Cancer Xenografts Are Activated by Local Delivery of IL-12 to Proliferate, Produce IFN-γ, and Eradicate Tumor Cells ¹

Lori Broderick; Sandra J. Yokota; Joshua Reineke; Edith Mathiowitz; Carleton C. Stewart; Maurice Barcos; Raymond J. Kelleher, Jr.; Richard B. Bankert

J Immunol (2005) 174 (2): 898–906.

Abstract

View articletitled, Human CD4+ Effector Memory T Cells Persisting in the Microenvironment of Lung Cancer Xenografts Are Activated by Local Delivery of IL-12 to Proliferate, Produce IFN-γ, and Eradicate Tumor Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Viral Delivery of an Epitope from Haemophilus influenzae Induces Central Nervous System Autoimmune Disease by Molecular Mimicry ¹

J. Ludovic Croxford; Holly A. Anger; Stephen D. Miller

J Immunol (2005) 174 (2): 907–917.

Abstract

View articletitled, Viral Delivery of an Epitope from Haemophilus influenzae Induces Central Nervous System Autoimmune Disease by Molecular Mimicry<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Resolution of a 16.8-Mb Autoimmunity-Regulating Rat Chromosome 4 Region into Multiple Encephalomyelitis Quantitative Trait Loci and Evidence for Epistasis ¹

Maja Jagodic; Monica Marta; Kristina Becanovic; Jian Rong Sheng; Rita Nohra; Tomas Olsson; Johnny C. Lorentzen

J Immunol (2005) 174 (2): 918–924.

Abstract

View articletitled, Resolution of a 16.8-Mb Autoimmunity-Regulating Rat Chromosome 4 Region into Multiple Encephalomyelitis Quantitative Trait Loci and Evidence for Epistasis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Different MHC Class I Heavy Chains Compete with Each Other for Folding Independently of β₂-Microglobulin and Peptide ¹

Sophie Tourdot; Mohamed Nejmeddine; Simon J. Powis; Keith G. Gould

J Immunol (2005) 174 (2): 925–933.

Abstract

View articletitled, Different MHC Class I Heavy Chains Compete with Each Other for Folding Independently of β2-Microglobulin and Peptide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Double-Edged Sword of Activation-Induced Cytidine Deaminase ¹

Xiaosheng Wu; Pedro Geraldes; Jeffrey L. Platt; Marilia Cascalho

J Immunol (2005) 174 (2): 934–941.

Abstract

View articletitled, The Double-Edged Sword of Activation-Induced Cytidine Deaminase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Quality of Recombinant Protein Determines the Amount of Autoreactivity Detected against the Tumor-Associated Epithelial Cell Adhesion Molecule Antigen: Low Frequency of Antibodies against the Natural Protein

Oliver Schmetzer; Gerhard Moldenhauer; Rainer Riesenberg; José Ricardo Pires; Peter Schlag; Antonio Pezzutto

J Immunol (2005) 174 (2): 942–952.

Abstract

View articletitled, Quality of Recombinant Protein Determines the Amount of Autoreactivity Detected against the Tumor-Associated Epithelial Cell Adhesion Molecule Antigen: Low Frequency of Antibodies against the Natural Protein

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Tristetraprolin Down-Regulates IL-2 Gene Expression through AU-Rich Element-Mediated mRNA Decay ¹

Rachel L. Ogilvie; Michelle Abelson; Heidi H. Hau; Irina Vlasova; Perry J. Blackshear; Paul R. Bohjanen

J Immunol (2005) 174 (2): 953–961.

Abstract

View articletitled, Tristetraprolin Down-Regulates IL-2 Gene Expression through AU-Rich Element-Mediated mRNA Decay<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Charged Amino Acid Residue in the Transmembrane/Cytoplasmic Region of Tapasin Influences MHC Class I Assembly and Maturation ¹

Jason L. Petersen; Heather D. Hickman-Miller; Mary M. McIlhaney; Shanna E. Vargas; Anthony W. Purcell; William H. Hildebrand; Joyce C. Solheim

J Immunol (2005) 174 (2): 962–969.

Abstract

View articletitled, A Charged Amino Acid Residue in the Transmembrane/Cytoplasmic Region of Tapasin Influences MHC Class I Assembly and Maturation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Rat Expresses Two Complement Factor C4 Proteins, but Only One Isotype Is Expressed in the Liver ¹

Christian Roos; Ralf Dressel; Bernhard Schmidt; Eberhard Günther; Lutz Walter

J Immunol (2005) 174 (2): 970–975.

Abstract

View articletitled, The Rat Expresses Two Complement Factor C4 Proteins, but Only One Isotype Is Expressed in the Liver<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vaccination with a Human High Molecular Weight Melanoma-Associated Antigen Mimotope Induces a Humoral Response Inhibiting Melanoma Cell Growth In Vitro ¹

Stefan Wagner; Christine Hafner; Dorothee Allwardt; Joanna Jasinska; Soldano Ferrone; Christoph C. Zielinski; Otto Scheiner; Ursula Wiedermann; Hubert Pehamberger; Heimo Breiteneder

J Immunol (2005) 174 (2): 976–982.

Abstract

View articletitled, Vaccination with a Human High Molecular Weight Melanoma-Associated Antigen Mimotope Induces a Humoral Response Inhibiting Melanoma Cell Growth In Vitro<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Reductions in IκBε and Changes in NF-κB Activity during B Lymphocyte Differentiation ¹

Stefan Doerre; Kristin Perkins Mesires; Kylle M. Daley; Thomas McCarty; Sonja Knoetig; Ronald B. Corley

J Immunol (2005) 174 (2): 983–991.

Abstract

View articletitled, Reductions in IκBε and Changes in NF-κB Activity during B Lymphocyte Differentiation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Innate Immunity in the Human Female Reproductive Tract: Antiviral Response of Uterine Epithelial Cells to the TLR3 Agonist Poly(I:C)¹

Todd M. Schaefer; John V. Fahey; Jacqueline A. Wright; Charles R. Wira

J Immunol (2005) 174 (2): 992–1002.

Abstract

View articletitled, Innate Immunity in the Human Female Reproductive Tract: Antiviral Response of Uterine Epithelial Cells to the TLR3 Agonist Poly(I:C)<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-αβ Secreted during Infection Is Necessary but Not Sufficient for Negative Feedback Regulation of IFN-αβ Signaling by Mycobacterium tuberculosis¹

Savita Prabhakar; Yaming Qiao; Antony Canova; Doris B. Tse; Richard Pine

J Immunol (2005) 174 (2): 1003–1012.

Abstract

View articletitled, IFN-αβ Secreted during Infection Is Necessary but Not Sufficient for Negative Feedback Regulation of IFN-αβ Signaling by Mycobacterium tuberculosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Abnormal Th1 Cell Differentiation and IFN-γ Production in T Lymphocytes from Motheaten Viable Mice Mutant for Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-1 ¹

Wen-Mei Yu; Siying Wang; Achsah D. Keegan; Mark S. Williams; Cheng-Kui Qu

J Immunol (2005) 174 (2): 1013–1019.

Abstract

View articletitled, Abnormal Th1 Cell Differentiation and IFN-γ Production in T Lymphocytes from Motheaten Viable Mice Mutant for Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Bacterial Lipoprotein Induces Resistance to Gram-Negative Sepsis in TLR4-Deficient Mice via Enhanced Bacterial Clearance ¹

Gavin C. O’Brien; Jiang Huai Wang; H. Paul Redmond

J Immunol (2005) 174 (2): 1020–1026.

Abstract

View articletitled, Bacterial Lipoprotein Induces Resistance to Gram-Negative Sepsis in TLR4-Deficient Mice via Enhanced Bacterial Clearance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distinct Roles for IL-4 and IL-10 in Regulating T2 Immunity during Allergic Bronchopulmonary Mycosis ¹

Yadira Hernandez; Shikha Arora; John R. Erb-Downward; Roderick A. McDonald; Galen B. Toews; Gary B. Huffnagle

J Immunol (2005) 174 (2): 1027–1036.

Abstract

View articletitled, Distinct Roles for IL-4 and IL-10 in Regulating T2 Immunity during Allergic Bronchopulmonary Mycosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Heterogeneity of Memory CD4 T Cell Responses in Different Conditions of Antigen Exposure and Persistence ¹

Alexandre Harari; Florence Vallelian; Pascal R. Meylan; Giuseppe Pantaleo

J Immunol (2005) 174 (2): 1037–1045.

Abstract

View articletitled, Functional Heterogeneity of Memory CD4 T Cell Responses in Different Conditions of Antigen Exposure and Persistence<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Restricted IgA Repertoire in Both B-1 and B-2 Cell-Derived Gut Plasmablasts ¹

Maaike Stoel; Han-Qing Jiang; Cleo C. van Diemen; Judy C. A. M. Bun; Peter M. Dammers; M. Christine Thurnheer; Frans G. M. Kroese; John J. Cebra; Nicolaas A. Bos

J Immunol (2005) 174 (2): 1046–1054.

Abstract

View articletitled, Restricted IgA Repertoire in Both B-1 and B-2 Cell-Derived Gut Plasmablasts<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

CXC Chemokine Ligand 16 Promotes Integrin-Mediated Adhesion of Liver-Infiltrating Lymphocytes to Cholangiocytes and Hepatocytes within the Inflamed Human Liver ¹

Mathis Heydtmann; Patricia F. Lalor; J. Albertus Eksteen; Stefan G. Hübscher; Mike Briskin; David H. Adams

J Immunol (2005) 174 (2): 1055–1062.

Abstract

View articletitled, CXC Chemokine Ligand 16 Promotes Integrin-Mediated Adhesion of Liver-Infiltrating Lymphocytes to Cholangiocytes and Hepatocytes within the Inflamed Human Liver<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mast Cells, Basophils, and Eosinophils Acquire Constitutive IL-4 and IL-13 Transcripts during Lineage Differentiation That Are Sufficient for Rapid Cytokine Production ¹

André Gessner; Katja Mohrs; Markus Mohrs

J Immunol (2005) 174 (2): 1063–1072.

Abstract

View articletitled, Mast Cells, Basophils, and Eosinophils Acquire Constitutive IL-4 and IL-13 Transcripts during Lineage Differentiation That Are Sufficient for Rapid Cytokine Production<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A_2A Adenosine Receptor Induction Inhibits IFN-γ Production in Murine CD4⁺ T Cells ¹

Courtney M. Lappas; Jayson M. Rieger; Joel Linden

J Immunol (2005) 174 (2): 1073–1080.

Abstract

View articletitled, A2A Adenosine Receptor Induction Inhibits IFN-γ Production in Murine CD4+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TNF Receptor-Associated Factor 6 Is an Essential Mediator of CD40-Activated Proinflammatory Pathways in Monocytes and Macrophages ¹

Lata Mukundan; Gail A. Bishop; Kimberly Z. Head; Lihua Zhang; Larry M. Wahl; Jill Suttles

J Immunol (2005) 174 (2): 1081–1090.

Abstract

View articletitled, TNF Receptor-Associated Factor 6 Is an Essential Mediator of CD40-Activated Proinflammatory Pathways in Monocytes and Macrophages<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phospholipids Inhibit Lipopolysaccharide (LPS)-Induced Cell Activation: A Role for LPS-Binding Protein ¹

Mareile Mueller; Klaus Brandenburg; Russ Dedrick; Andra B. Schromm; Ulrich Seydel

J Immunol (2005) 174 (2): 1091–1096.

Abstract

View articletitled, Phospholipids Inhibit Lipopolysaccharide (LPS)-Induced Cell Activation: A Role for LPS-Binding Protein<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lipoprotein I, a TLR2/4 Ligand Modulates Th2-Driven Allergic Immune Responses

Hilde Revets; Gwenda Pynaert; Johan Grooten; Patrick De Baetselier

J Immunol (2005) 174 (2): 1097–1103.

Abstract

View articletitled, Lipoprotein I, a TLR2/4 Ligand Modulates Th2-Driven Allergic Immune Responses

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CLINICAL IMMUNOLOGY

Changes in the Novel Orphan, C5a Receptor (C5L2), during Experimental Sepsis and Sepsis in Humans ¹

Markus Huber-Lang; J. Vidya Sarma; Daniel Rittirsch; Heike Schreiber; Manfred Weiss; Michael Flierl; Ellen Younkin; Marion Schneider; Heidemarie Suger-Wiedeck; Florian Gebhard; Shannon D. McClintock; Thomas Neff; Firas Zetoune; Uwe Bruckner; Ren-Feng Guo; Peter N. Monk; Peter A. Ward

J Immunol (2005) 174 (2): 1104–1110.

Abstract

View articletitled, Changes in the Novel Orphan, C5a Receptor (C5L2), during Experimental Sepsis and Sepsis in Humans<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Role of Three Major New Zealand Black-Derived Loci Linked with Yaa-Induced Murine Lupus Nephritis ¹

Shuichi Kikuchi; Liliane Fossati-Jimack; Thomas Moll; Hirofumi Amano; Eri Amano; Akinori Ida; Nabila Ibnou-Zekri; Catherine Laporte; Marie-Laure Santiago-Raber; Stephen J. Rozzo; Brian L. Kotzin; Shozo Izui

J Immunol (2005) 174 (2): 1111–1117.

Abstract

View articletitled, Differential Role of Three Major New Zealand Black-Derived Loci Linked with Yaa-Induced Murine Lupus Nephritis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Requirement for CD28 May Not Be Absolute for Collagen-Induced Arthritis: Study with HLA-DQ8 Transgenic Mice ¹

Veena Taneja; Neelam Taneja; Marshall Behrens; Marie M. Griffiths; Harvinder S. Luthra; Chella S. David

J Immunol (2005) 174 (2): 1118–1125.

Abstract

View articletitled, Requirement for CD28 May Not Be Absolute for Collagen-Induced Arthritis: Study with HLA-DQ8 Transgenic Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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