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Issues
1 November 2005
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
The Devil in the Details: The Emerging Role of Anticitrulline Autoimmunity in Rheumatoid Arthritis
J Immunol (2005) 175 (9): 5575–5580.
CUTTING EDGE
Cutting Edge: TRAIL Deficiency Accelerates Hematological Malignancies1
Nadeen Zerafa; Jennifer A. Westwood; Erika Cretney; Sally Mitchell; Paul Waring; Manuela Iezzi; Mark J. Smyth
J Immunol (2005) 175 (9): 5586–5590.
Cutting Edge: MyD88 Controls Phagocyte NADPH Oxidase Function and Killing of Gram-Negative Bacteria1
J Immunol (2005) 175 (9): 5596–5600.
Cutting Edge: A Critical Role for Gene Silencing in Preventing Excessive Type 1 Immunity1
J Immunol (2005) 175 (9): 5606–5610.
Cutting Edge: Double-Stranded DNA Breaks in the IgV Region Gene Were Detected at Lower Frequency in Affinity-Maturation Impeded GANP−/− Mice1
Yousuke Kawatani; Hideya Igarashi; Takeshi Matsui; Kazuhiko Kuwahara; Satoru Fujimura; Nobukazu Okamoto; Katsumasa Takagi; Nobuo Sakaguchi
J Immunol (2005) 175 (9): 5615–5618.
Cutting Edge: Memory CD8 T Cell Maturation Occurs Independently of CD8αα 1
J Immunol (2005) 175 (9): 5619–5623.
Cutting Edge: Early IFN-γ Signaling Directly Enhances Primary Antiviral CD4+ T Cell Responses1
J Immunol (2005) 175 (9): 5624–5628.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
CD4-Dependent Signaling Is Required for a Late Checkpoint during Th2 Development Associated with Resistance to Activation-Induced Cell Death1
J Immunol (2005) 175 (9): 5629–5636.
Cholera Toxin B-Subunit Prevents Activation and Proliferation of Human CD4+ T Cells by Activation of a Neutral Sphingomyelinase in Lipid Rafts1
Alexandre K. Rouquette-Jazdanian; Arnaud Foussat; Laurence Lamy; Claudette Pelassy; Patricia Lagadec; Jean-Philippe Breittmayer; Claude Aussel
J Immunol (2005) 175 (9): 5637–5648.
Distinct Effector Mechanisms in the Development of Autoimmune Neuropathy versus Diabetes in Nonobese Diabetic Mice1
J Immunol (2005) 175 (9): 5649–5655.
Lyme Arthritis Synovial γδ T Cells Instruct Dendritic Cells via Fas Ligand1
J Immunol (2005) 175 (9): 5656–5665.
Durable Human Memory T Cells Quantifiable by Cultured Enzyme-Linked Immunospot Assays Are Induced by Heterologous Prime Boost Immunization and Correlate with Protection against Malaria1
Sheila M. Keating; Philip Bejon; Tamara Berthoud; Jenni M. Vuola; Stephen Todryk; Daniel P. Webster; Susanna J. Dunachie; Vasee S. Moorthy; Samuel J. McConkey; Sarah C. Gilbert; Adrian V. S. Hill
J Immunol (2005) 175 (9): 5675–5680.
Murine Plasmacytoid Dendritic Cells Produce IFN-γ upon IL-4 Stimulation1
Akira Suto; Hiroshi Nakajima; Naoki Tokumasa; Hiroaki Takatori; Shin-ichiro Kagami; Kotaro Suzuki; Itsuo Iwamoto
J Immunol (2005) 175 (9): 5681–5689.
Estrogen Receptor α (ERα) Deficiency in Macrophages Results in Increased Stimulation of CD4+ T Cells while 17β-Estradiol Acts through ERα to Increase IL-4 and GATA-3 Expression in CD4+ T Cells Independent of Antigen Presentation1
K. Chad Lambert; Edward M. Curran; Barbara M. Judy; Gregg N. Milligan; Dennis B. Lubahn; D. Mark Estes
J Immunol (2005) 175 (9): 5716–5723.
Ex Vivo Rapamycin Generates Donor Th2 Cells That Potently Inhibit Graft-versus-Host Disease and Graft-versus-Tumor Effects via an IL-4-Dependent Mechanism1
Jason E. Foley; Unsu Jung; Angel Miera; Todd Borenstein; Jacopo Mariotti; Michael Eckhaus; Barbara E. Bierer; Daniel H. Fowler
J Immunol (2005) 175 (9): 5732–5743.
Physiological Levels of 15-Deoxy-Δ12,14-Prostaglandin J2 Prime Eotaxin-Induced Chemotaxis on Human Eosinophils through Peroxisome Proliferator-Activated Receptor-γ Ligation1
Yoshiki Kobayashi; Shigeharu Ueki; Gulixian Mahemuti; Takahito Chiba; Hajime Oyamada; Norihiro Saito; Akira Kanda; Hiroyuki Kayaba; Junichi Chihara
J Immunol (2005) 175 (9): 5744–5750.
Molecular Signature of Recent Thymic Selection Events on Effector and Regulatory CD4+ T Lymphocytes1
J Immunol (2005) 175 (9): 5751–5758.
Human CD4+ T Cells Are Predominantly Distributed among Six Phenotypically and Functionally Distinct Subsets1
J Immunol (2005) 175 (9): 5765–5773.
Differential Effects of B and T Lymphocyte Attenuator and Programmed Death-1 on Acceptance of Partially versus Fully MHC-Mismatched Cardiac Allografts1
Ran Tao; Liqing Wang; Rongxiang Han; Tao Wang; Qunrui Ye; Takasu Honjo; Theresa L. Murphy; Kenneth M. Murphy; Wayne W. Hancock
J Immunol (2005) 175 (9): 5774–5782.
JNK1 Is Essential for CD8+ T Cell-Mediated Tumor Immune Surveillance1
Yunfei Gao; Jian Tao; Ming O. Li; Dongqing Zhang; Hongbo Chi; Octavian Henegariu; Susan M. Kaech; Roger J. Davis; Richard A. Flavell; Zhinan Yin
J Immunol (2005) 175 (9): 5783–5789.
NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Receptors1
Béatrice Le Maux Chansac; Alessandro Moretta; Isabelle Vergnon; Paule Opolon; Yann Lécluse; Dominique Grunenwald; Marek Kubin; Jean-Charles Soria; Salem Chouaib; Fathia Mami-Chouaib
J Immunol (2005) 175 (9): 5790–5798.
Recognition of Fresh Human Tumor by Human Peripheral Blood Lymphocytes Transduced with a Bicistronic Retroviral Vector Encoding a Murine Anti-p53 TCR
Cyrille J. Cohen; Zhili Zheng; Regina Bray; Yangbing Zhao; Linda A. Sherman; Steven A. Rosenberg; Richard A. Morgan
J Immunol (2005) 175 (9): 5799–5808.
CD4 T Cell-Independent Antibody Response Promotes Resolution of Primary Influenza Infection and Helps to Prevent Reinfection1
Byung O. Lee; Javier Rangel-Moreno; Juan E. Moyron-Quiroz; Louise Hartson; Melissa Makris; Frank Sprague; Frances E. Lund; Troy D. Randall
J Immunol (2005) 175 (9): 5827–5838.
The Earliest Thymic Progenitors in Adults Are Restricted to T, NK, and Dendritic Cell Lineage and Have a Potential to Form More Diverse TCRβ Chains than Fetal Progenitors1
Min Lu; Risa Tayu; Tomokatsu Ikawa; Kyoko Masuda; Isamu Matsumoto; Hideo Mugishima; Hiroshi Kawamoto; Yoshimoto Katsura
J Immunol (2005) 175 (9): 5848–5856.
Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis1
Nadine Hövelmeyer; Zhenyue Hao; Ksanthi Kranidioti; George Kassiotis; Thorsten Buch; Friederike Frommer; Lennart von Hoch; Dana Kramer; Liliana Minichiello; George Kollias; Hans Lassmann; Ari Waisman
J Immunol (2005) 175 (9): 5875–5884.
IL-12 and IL-10 Expression Synergize to Induce the Immune-Mediated Eradication of Established Colon and Mammary Tumors and Lung Metastasis1
J Immunol (2005) 175 (9): 5885–5894.
Molecular Signatures Distinguish Human Central Memory from Effector Memory CD8 T Cell Subsets1
J Immunol (2005) 175 (9): 5895–5903.
Respiratory Syncytial Virus Infection of Monocyte-Derived Dendritic Cells Decreases Their Capacity to Activate CD4 T Cells
Patricia M. A. de Graaff; Esther C. de Jong; Toni M. van Capel; Mariska E. A. van Dijk; Paul J. M. Roholl; Jolande Boes; Willem Luytjes; Jan L. L. Kimpen; Grada M. van Bleek
J Immunol (2005) 175 (9): 5904–5911.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Ig Gene Rearrangement Steps Are Initiated in Early Human Precursor B Cell Subsets and Correlate with Specific Transcription Factor Expression1
Menno C. van Zelm; Mirjam van der Burg; Dick de Ridder; Barbara H. Barendregt; Edwin F. E. de Haas; Marcel J. T. Reinders; Arjan C. Lankester; Tom Révész; Frank J. T. Staal; Jacques J. M. van Dongen
J Immunol (2005) 175 (9): 5912–5922.
Tec Kinases Regulate TCR-Mediated Recruitment of Signaling Molecules and Integrin-Dependent Cell Adhesion1
J Immunol (2005) 175 (9): 5923–5930.
Differential Processing of Autoantigens in Lysosomes from Human Monocyte-Derived and Peripheral Blood Dendritic Cells1
Timo Burster; Alexander Beck; Eva Tolosa; Petra Schnorrer; Robert Weissert; Michael Reich; Marianne Kraus; Hubert Kalbacher; Hans-Ulrich Häring; Ekkehard Weber; Herman Overkleeft; Christoph Driessen
J Immunol (2005) 175 (9): 5940–5949.
Impact of Peptides on the Recognition of HLA Class I Molecules by Human HLA Antibodies
Arend Mulder; Chantal Eijsink; Michel G. D. Kester; Marry E. I. Franke; Marrie J. Kardol; Mirjam H. M. Heemskerk; Cees van Kooten; Frank A. Verreck; Jan Wouter Drijfhout; Frits Koning; Ilias I. N. Doxiadis; Frans H. J. Claas
J Immunol (2005) 175 (9): 5950–5957.
Signaling through a Mutant IFN-γ Receptor
Ana P. Costa-Pereira; Heike M. Hermanns; Hayaatun Is’harc; Timothy M. Williams; Diane Watling; Velmurugesan Arulampalam; Sally J. Newman; Peter C. Heinrich; Ian M. Kerr
J Immunol (2005) 175 (9): 5958–5965.
Epigenetic Control of Highly Homologous Killer Ig-Like Receptor Gene Alleles1
J Immunol (2005) 175 (9): 5966–5974.
The Cyclic AMP Response Element Modulator Regulates Transcription of the TCR ζ-Chain1
Klaus Tenbrock; Vasileios C. Kyttaris; Martina Ahlmann; Jan Mauno Ehrchen; Mate Tolnay; Harutyun Melkonyan; Christian Mawrin; Johannes Roth; Clemens Sorg; Yuang-Taung Juang; George C. Tsokos
J Immunol (2005) 175 (9): 5975–5980.
Transcriptional Activators of Helper T Cell Fate Are Required for Establishment but Not Maintenance of Signature Cytokine Expression1
J Immunol (2005) 175 (9): 5981–5985.
IMMUNOGENETICS
The High Frequency Indian Rhesus Macaque MHC Class I Molecule, Mamu-B*01, Does Not Appear to Be Involved in CD8+ T Lymphocyte Responses to SIVmac2391
John T. Loffredo; John Sidney; Shari Piaskowski; Andrew Szymanski; Jessica Furlott; Richard Rudersdorf; Jason Reed; Bjoern Peters; Heather D. Hickman-Miller; Wilfried Bardet; William M. Rehrauer; David H. O’Connor; Nancy A. Wilson; William H. Hildebrand; Alessandro Sette; David I. Watkins
J Immunol (2005) 175 (9): 5986–5997.
HOST DEFENSE
Distinct Regulation of H2-M3-Restricted Memory T Cell Responses in Lymph Node and Spleen1
J Immunol (2005) 175 (9): 5998–6005.
Osteopontin Is Not Required for the Development of Th1 Responses and Viral Immunity1
J Immunol (2005) 175 (9): 6006–6013.
TNF Receptor-Associated Factor 6-Dependent CD40 Signaling Primes Macrophages to Acquire Antimicrobial Activity in Response to TNF-α1
Rosa M. Andrade; Matthew Wessendarp; Jose-Andres C. Portillo; Jun-Qi Yang; Francisco J. Gomez; Joan E. Durbin; Gail A. Bishop; Carlos S. Subauste
J Immunol (2005) 175 (9): 6014–6021.
Differential TLR Recognition of Leptospiral Lipid A and Lipopolysaccharide in Murine and Human Cells1
Marie-Anne Nahori; Edith Fournié-Amazouz; Nanette S. Que-Gewirth; Viviane Balloy; Michel Chignard; Christian R. H. Raetz; Isabelle Saint Girons; Catherine Werts
J Immunol (2005) 175 (9): 6022–6031.
Dendritic Cell Maturation, but Not CD8+ T Cell Induction, Is Dependent on Type I IFN Signaling during Vaccination with Adenovirus Vectors1
J Immunol (2005) 175 (9): 6032–6041.
The MyD88-Dependent, but Not the MyD88-Independent, Pathway of TLR4 Signaling Is Important in Clearing Nontypeable Haemophilus influenzae from the Mouse Lung1
Catharina W. Wieland; Sandrine Florquin; Nico A. Maris; Kasper Hoebe; Bruce Beutler; Kiyoshi Takeda; Shizuo Akira; Tom van der Poll
J Immunol (2005) 175 (9): 6042–6049.
MARCO Is the Major Binding Receptor for Unopsonized Particles and Bacteria on Human Alveolar Macrophages1
Mohamed S. Arredouani; Aiyappa Palecanda; Henry Koziel; Yuh-Ching Huang; Amy Imrich; Timothy H. Sulahian; Yao Yu Ning; Zhiping Yang; Timo Pikkarainen; Marko Sankala; Sara O. Vargas; Motohiro Takeya; Karl Tryggvason; Lester Kobzik
J Immunol (2005) 175 (9): 6058–6064.
Pattern Recognition Molecules Activated by Chlamydia muridarum Infection of Cloned Murine Oviduct Epithelial Cell Lines1
J Immunol (2005) 175 (9): 6065–6075.
INFLAMMATION
Arginine-Specific Gingipains from Porphyromonas gingivalis Stimulate Production of Hepatocyte Growth Factor (Scatter Factor) through Protease-Activated Receptors in Human Gingival Fibroblasts in Culture1
Akiko Uehara; Koji Muramoto; Takahisa Imamura; Koji Nakayama; Jan Potempa; James Travis; Shunji Sugawara; Haruhiko Takada
J Immunol (2005) 175 (9): 6076–6084.
IL-4 Inhibits the Expression of Mouse Formyl Peptide Receptor 2, a Receptor for Amyloid β1–42, in TNF-α-Activated Microglia12
J Immunol (2005) 175 (9): 6100–6106.
CLINICAL IMMUNOLOGY
Low-Level CD4+ T Cell Activation Is Associated with Low Susceptibility to HIV-1 Infection1
Fransje A. Koning; Sigrid A. Otto; Mette D. Hazenberg; Linda Dekker; Maria Prins; Frank Miedema; Hanneke Schuitemaker
J Immunol (2005) 175 (9): 6117–6122.
Selection of T Cell Clones Expressing High-Affinity Public TCRs within Human Cytomegalovirus-Specific CD8 T Cell Responses1
Lydie Trautmann; Marie Rimbert; Klara Echasserieau; Xavier Saulquin; Bérangère Neveu; Julie Dechanet; Vincenzo Cerundolo; Marc Bonneville
J Immunol (2005) 175 (9): 6123–6132.
CD8brightCD56+ T Cells Are Cytotoxic Effectors in Patients with Active Behçet’s Uveitis1
J Immunol (2005) 175 (9): 6133–6142.
Innate Immunity and Human B Cell Clonal Expansion: Effects on the Recirculating B2 Subpopulation1
Patricia K. A. Mongini; John K. Inman; Hanna Han; Susan L. Kalled; Rasem J. Fattah; Steven McCormick
J Immunol (2005) 175 (9): 6143–6154.
Selective Activation of Peripheral Blood T Cell Subsets by Endotoxin Infusion in Healthy Human Subjects Corresponds to Differential Chemokine Activation1
Asit K. De; Carol L. Miller-Graziano; Steve E. Calvano; Krzysztof Laudanski; Stephen F. Lowry; Lyle L. Moldawer; Daniel G. Remick, Jr; Natasa Rajicic; David Schoenfeld; Ronald G. Tompkins
J Immunol (2005) 175 (9): 6155–6162.
A Role for B Cell-Activating Factor of the TNF Family in Chemically Induced Autoimmunity1
J Immunol (2005) 175 (9): 6163–6168.
Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma
Steven A. Rosenberg; Richard M. Sherry; Kathleen E. Morton; William J. Scharfman; James C. Yang; Suzanne L. Topalian; Richard E. Royal; Udai Kammula; Nicholas P. Restifo; Marybeth S. Hughes; Douglas Schwartzentruber; David M. Berman; Susan L. Schwarz; Lien T. Ngo; Sharon A. Mavroukakis; Donald E. White; Seth M. Steinberg
J Immunol (2005) 175 (9): 6169–6176.
IL-17 Enhances the Net Angiogenic Activity and In Vivo Growth of Human Non-Small Cell Lung Cancer in SCID Mice through Promoting CXCR-2-Dependent Angiogenesis1
Muneo Numasaki; Mika Watanabe; Takashi Suzuki; Hidenori Takahashi; Akira Nakamura; Florencia McAllister; Takanori Hishinuma; Junichi Goto; Michael T. Lotze; Jay K. Kolls; Hidetada Sasaki
J Immunol (2005) 175 (9): 6177–6189.
CD80/CD86 Costimulation Regulates Acute Vascular Rejection1
Karoline A. Hosiawa; Hao Wang; Mark E. DeVries; Bertha Garcia; Weihua Liu; Dejun Zhou; Ali Akram; Jifu Jiang; Hongtao Sun; Mark J. Cameron; Robert Zhong; David J. Kelvin
J Immunol (2005) 175 (9): 6197–6204.
Increased Susceptibility to Complement Attack due to Down-Regulation of Decay-Accelerating Factor/CD55 in Dysferlin-Deficient Muscular Dystrophy12
Katrin Wenzel; Joanna Zabojszcza; Miriam Carl; Semjon Taubert; Antje Lass; Claire L. Harris; Mengfatt Ho; Herbert Schulz; Oliver Hummel; Norbert Hubner; Karl Josef Osterziel; Simone Spuler
J Immunol (2005) 175 (9): 6219–6225.
A Suppressive Oligodeoxynucleotide Enhances the Efficacy of Myelin Cocktail/IL-4-Tolerizing DNA Vaccination and Treats Autoimmune Disease1
Peggy P. Ho; Paulo Fontoura; Michael Platten; Raymond A. Sobel; Jason J. DeVoss; Lowen Y. Lee; Brian A. Kidd; Beren H. Tomooka; Julien Capers; Ashish Agrawal; Rohit Gupta; Jonathan Zernik; Michael K. Yee; Byung J. Lee; Hideki Garren; William H. Robinson; Lawrence Steinman
J Immunol (2005) 175 (9): 6226–6234.
CORRECTIONS
MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell Receptor ligation facilitates switch to IgG production
J Immunol (2005) 175 (9): 6235.
Dendritic cell-mediated cross-presentation of antigens derived from colon carcinoma cells exposed to a highly cytotoxic multidrug regimen with gemcitabine, oxaliplatin, 5-fluorouracil, and leucovorin, elicits a powerful human antigen-specific CTL response with antitumor activity in vitro
P. Correale; M. G. Cusi; M. T. Del Vecchio; A. Aquino; S. Prete; K. Y. Tsang; L. Micheli; C. Nencini; M. La Placa; F. Montagnani; C. Terrosi; M. Caraglia; V. Formica; G. Giorgi; E. Bonmassar; G. Francini
J Immunol (2005) 175 (9): 6235.
Effects of Bcl-2 levels on Fas signaling-induced caspase-3 activation: molecular genetic tests of computational model predictions
J Immunol (2005) 175 (9): 6235–6237.
Runx3 regulates integrin αE/CD103 and CD4 expression during development of CD4−/CD8+ T cells
B. Grueter; M. Petter; T. Egawa; K. Laule-Kilian; C. J. Aldrian; A. Wuerch; Y. Ludwig; H. Fukuyama; H. Wardemann; R. Waldschuetz; T. Möröy; I. Taniuchi; V. Steimle; D. R. Littman; M. Ehlers
J Immunol (2005) 175 (9): 6238.
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