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J Immunol (2006) 176 (5): 2679–2680.

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PILLARS OF IMMUNOLOGY

The TCR of Mice and Men

Stephen M. Hedrick

J Immunol (2006) 176 (5): 2681–2682.

View articletitled, The TCR of Mice and Men

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Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302.

John Kappler; Ralph Kubo; Kathryn Haskins; Charles Hannum; Philippa Marrack; Michele Pigeon; Bradley McIntyre; James Allison; Ian Trowbridge

J Immunol (2006) 176 (5): 2683–2690.

View articletitled, Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302.

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BRIEF REVIEWS

Patients, Pathogens, and Protective Immunity: The Relevance of Virus-Induced Alloreactivity in Transplantation

Brent Koehn; Shivaprakash Gangappa; Joeseph D. Miller; Rafi Ahmed; Christian P. Larsen

J Immunol (2006) 176 (5): 2691–2696.

Abstract

View articletitled, Patients, Pathogens, and Protective Immunity: The Relevance of Virus-Induced Alloreactivity in Transplantation

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CUTTING EDGE

Cutting Edge: HLA-B27 Acquires Many N-Terminal Dibasic Peptides: Coupling Cytosolic Peptide Stability to Antigen Presentation ¹

Carla A. Herberts; Joost J. Neijssen; Jolanda de Haan; Lennert Janssen; Jan Wouter Drijfhout; Eric A. Reits; Jacques J. Neefjes

J Immunol (2006) 176 (5): 2697–2701.

Abstract

View articletitled, Cutting Edge: HLA-B27 Acquires Many N-Terminal Dibasic Peptides: Coupling Cytosolic Peptide Stability to Antigen Presentation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Supplementary data

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Hormonal Regulation of B Cell Development: 17β-Estradiol Impairs Negative Selection of High-Affinity DNA-Reactive B Cells at More Than One Developmental Checkpoint ¹

Christine M. Grimaldi; Venkatesh Jeganathan; Betty Diamond

J Immunol (2006) 176 (5): 2703–2710.

Abstract

View articletitled, Hormonal Regulation of B Cell Development: 17β-Estradiol Impairs Negative Selection of High-Affinity DNA-Reactive B Cells at More Than One Developmental Checkpoint<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes ¹

Jing Chen; Isharat Yusuf; Hilde-Marie Andersen; David A. Fruman

J Immunol (2006) 176 (5): 2711–2721.

Abstract

View articletitled, FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Chemoimmunotherapy of Tumors: Cyclophosphamide Synergizes with Exosome Based Vaccines ¹

Julien Taieb; Nathalie Chaput; Noël Schartz; Stéphan Roux; Sophie Novault; Cédric Ménard; François Ghiringhelli; Magali Terme; Antoine F. Carpentier; Guillaume Darrasse-Jèse; François Lemonnier; Laurence Zitvogel

J Immunol (2006) 176 (5): 2722–2729.

Abstract

View articletitled, Chemoimmunotherapy of Tumors: Cyclophosphamide Synergizes with Exosome Based Vaccines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Prolonged TCR/CD28 Engagement Drives IL-2-Independent T Cell Clonal Expansion through Signaling Mediated by the Mammalian Target of Rapamycin ¹

Sara Colombetti; Veronica Basso; Daniel L. Mueller; Anna Mondino

J Immunol (2006) 176 (5): 2730–2738.

Abstract

View articletitled, Prolonged TCR/CD28 Engagement Drives IL-2-Independent T Cell Clonal Expansion through Signaling Mediated by the Mammalian Target of Rapamycin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-15-Dependent Induction of 4-1BB Promotes Antigen-Independent CD8 Memory T Cell Survival ¹

Gayle Pulle; Mariana Vidric; Tania H. Watts

J Immunol (2006) 176 (5): 2739–2748.

Abstract

View articletitled, IL-15-Dependent Induction of 4-1BB Promotes Antigen-Independent CD8 Memory T Cell Survival<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dendritic Cell-Mediated Induction of Mucosal Cytotoxic Responses following Intravaginal Immunization with the Nontoxic B Subunit of Cholera Toxin ¹

Carmelo Luci; Catherine Hervouet; Déborah Rousseau; Jan Holmgren; Cecil Czerkinsky; Fabienne Anjuère

J Immunol (2006) 176 (5): 2749–2757.

Abstract

View articletitled, Dendritic Cell-Mediated Induction of Mucosal Cytotoxic Responses following Intravaginal Immunization with the Nontoxic B Subunit of Cholera Toxin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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B Cell Induction of IL-13 Expression in NK Cells: Role of CD244 and SLAM-Associated Protein

Ning Gao; Pamela Schwartzberg; Julie A. Wilder; Bruce R. Blazar; Dorothy Yuan

J Immunol (2006) 176 (5): 2758–2764.

Abstract

View articletitled, B Cell Induction of IL-13 Expression in NK Cells: Role of CD244 and SLAM-Associated Protein

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Oxidative Stress Promotes Polarization of Human T Cell Differentiation Toward a T Helper 2 Phenotype ¹

Miranda R. King; Anisa S. Ismail; Laurie S. Davis; David R. Karp

J Immunol (2006) 176 (5): 2765–2772.

Abstract

View articletitled, Oxidative Stress Promotes Polarization of Human T Cell Differentiation Toward a T Helper 2 Phenotype<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-27 Suppresses CD28-Medicated IL-2 Production through Suppressor of Cytokine Signaling 3 ¹

Toshiyuki Owaki; Masayuki Asakawa; Sadahiro Kamiya; Kiyoshi Takeda; Fumio Fukai; Junichiro Mizuguchi; Takayuki Yoshimoto

J Immunol (2006) 176 (5): 2773–2780.

Abstract

View articletitled, IL-27 Suppresses CD28-Medicated IL-2 Production through Suppressor of Cytokine Signaling 3<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein-Reactive CD4⁺ T Cells in Human Subjects ¹

Junbao Yang; Nancy A. Danke; DeAnna Berger; Sandra Reichstetter; Helena Reijonen; Carla Greenbaum; Catherine Pihoker; Eddie A. James; William W. Kwok

J Immunol (2006) 176 (5): 2781–2789.

Abstract

View articletitled, Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein-Reactive CD4+ T Cells in Human Subjects<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Recombinant Ig-Like Transcript 3-Fc Modulates T Cell Responses via Induction of Th Anergy and Differentiation of CD8⁺ T Suppressor Cells ¹

Seunghee Kim-Schulze; Luigi Scotto; George Vlad; Flavia Piazza; Hana Lin; Zhuoru Liu; Raffaello Cortesini; Nicole Suciu-Foca

J Immunol (2006) 176 (5): 2790–2798.

Abstract

View articletitled, Recombinant Ig-Like Transcript 3-Fc Modulates T Cell Responses via Induction of Th Anergy and Differentiation of CD8+ T Suppressor Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Antibody-Induced Transplantation Tolerance That Is Dependent on Thymus-Derived Regulatory T Cells ¹

Shaoping Deng; Daniel J. Moore; Xiaolun Huang; Mohammad Mohiuddin; Major K. Lee, IV; Ergun Velidedeoglu; Moh-Moh Lian; Meredith Chiaccio; Samsher Sonawane; Anton Orlin; Jing Wang; Haiying Chen; Andrew Caton; Robert Zhong; James F. Markmann

J Immunol (2006) 176 (5): 2799–2807.

Abstract

View articletitled, Antibody-Induced Transplantation Tolerance That Is Dependent on Thymus-Derived Regulatory T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulated Compartmentalization of Programmed Cell Death-1 Discriminates CD4⁺CD25⁺ Resting Regulatory T Cells from Activated T Cells ¹

Giorgio Raimondi; William J. Shufesky; Daisuke Tokita; Adrian E. Morelli; Angus W. Thomson

J Immunol (2006) 176 (5): 2808–2816.

Abstract

View articletitled, Regulated Compartmentalization of Programmed Cell Death-1 Discriminates CD4+CD25+ Resting Regulatory T Cells from Activated T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dengue Virus-Reactive CD8⁺ T Cells Display Quantitative and Qualitative Differences in Their Response to Variant Epitopes of Heterologous Viral Serotypes ¹

Hema S. Bashyam; Sharone Green; Alan L. Rothman

J Immunol (2006) 176 (5): 2817–2824.

Abstract

View articletitled, Dengue Virus-Reactive CD8+ T Cells Display Quantitative and Qualitative Differences in Their Response to Variant Epitopes of Heterologous Viral Serotypes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Dual-Specific Binding of Dengue Virus and Target Cells for the Antibody-Dependent Enhancement of Dengue Virus Infection ¹

Kao-Jean Huang; Yu-Ching Yang; Yee-Shin Lin; Jyh-Hsiung Huang; Hsiao-Sheng Liu; Trai-Ming Yeh; Shun-Hua Chen; Ching-Chuan Liu; Huan-Yao Lei

J Immunol (2006) 176 (5): 2825–2832.

Abstract

View articletitled, The Dual-Specific Binding of Dengue Virus and Target Cells for the Antibody-Dependent Enhancement of Dengue Virus Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Quantitative Analysis of Phosphotyrosine Signaling Networks Triggered by CD3 and CD28 Costimulation in Jurkat Cells ¹

Ji-Eun Kim; Forest M. White

J Immunol (2006) 176 (5): 2833–2843.

Abstract

View articletitled, Quantitative Analysis of Phosphotyrosine Signaling Networks Triggered by CD3 and CD28 Costimulation in Jurkat Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Identification of Oncofetal Antigen/Immature Laminin Receptor Protein Epitopes That Activate BALB/c Mouse OFA/iLRP-Specific Effector and Regulatory T Cell Clones ¹

James W. Rohrer; Adel L. Barsoum; Joseph H. Coggin, Jr.

J Immunol (2006) 176 (5): 2844–2856.

Abstract

View articletitled, Identification of Oncofetal Antigen/Immature Laminin Receptor Protein Epitopes That Activate BALB/c Mouse OFA/iLRP-Specific Effector and Regulatory T Cell Clones<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Self-Limitation of Th1-Mediated Inflammation by IFN-γ ¹

Markus Feuerer; Katharina Eulenburg; Christoph Loddenkemper; Alf Hamann; Jochen Huehn

J Immunol (2006) 176 (5): 2857–2863.

Abstract

View articletitled, Self-Limitation of Th1-Mediated Inflammation by IFN-γ<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Immunogenicity and Immunomodulatory Function of Osteogenic Cells Differentiated from Mesenchymal Stem Cells

Hua Liu; David Michael Kemeny; Boon Chin Heng; Hong Wei Ouyang; Alirio J. Melendez; Tong Cao

J Immunol (2006) 176 (5): 2864–2871.

Abstract

View articletitled, The Immunogenicity and Immunomodulatory Function of Osteogenic Cells Differentiated from Mesenchymal Stem Cells

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Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice

Seng-Lai Tan; Jingyong Zhao; Chen Bi; XinYi Cynthia Chen; Deena L. Hepburn; Jian Wang; Jonathon D. Sedgwick; Subba R. Chintalacharuvu; Songqing Na

J Immunol (2006) 176 (5): 2872–2879.

Abstract

View articletitled, Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice

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Lipoteichoic Acid Increases TLR and Functional Chemokine Expression while Reducing Dentin Formation in In Vitro Differentiated Human Odontoblasts

Stéphanie H. Durand; Vincent Flacher; Annick Roméas; Florence Carrouel; Evelyne Colomb; Claude Vincent; Henry Magloire; Marie-Lise Couble; Françoise Bleicher; Marie-Jeanne Staquet; Serge Lebecque; Jean-Christophe Farges

J Immunol (2006) 176 (5): 2880–2887.

Abstract

View articletitled, Lipoteichoic Acid Increases TLR and Functional Chemokine Expression while Reducing Dentin Formation in In Vitro Differentiated Human Odontoblasts

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TLR7/8 Triggering Exerts Opposing Effects in Acute versus Latent HIV Infection ¹

Erika Schlaepfer; Annette Audigé; Helene Joller; Roberto F. Speck

J Immunol (2006) 176 (5): 2888–2895.

Abstract

View articletitled, TLR7/8 Triggering Exerts Opposing Effects in Acute versus Latent HIV Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-18 Reduces Ultraviolet Radiation-Induced DNA Damage and Thereby Affects Photoimmunosuppression ¹

Agatha Schwarz; Akira Maeda; Sonja Ständer; Harry van Steeg; Thomas Schwarz

J Immunol (2006) 176 (5): 2896–2901.

Abstract

View articletitled, IL-18 Reduces Ultraviolet Radiation-Induced DNA Damage and Thereby Affects Photoimmunosuppression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control ¹

Fabrizio Vianello; Natalia Papeta; Tao Chen; Paul Kraft; Natasha White; William K. Hart; Moritz F. Kircher; Eric Swart; Sarah Rhee; Giorgio Palù; Daniel Irimia; Mehmet Toner; Ralph Weissleder; Mark C. Poznansky

J Immunol (2006) 176 (5): 2902–2914.

Abstract

View articletitled, Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity ¹

Nader Omidvar; Eddie C. Y. Wang; Paul Brennan; M. Paula Longhi; Richard A. G. Smith; B. Paul Morgan

J Immunol (2006) 176 (5): 2915–2923.

Abstract

View articletitled, Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Directed Differentiation of Human Embryonic Stem Cells into Functional Dendritic Cells through the Myeloid Pathway ¹

Igor I. Slukvin; Maxim A. Vodyanik; James A. Thomson; Maryna E. Gumenyuk; Kyung-Dal Choi

J Immunol (2006) 176 (5): 2924–2932.

Abstract

View articletitled, Directed Differentiation of Human Embryonic Stem Cells into Functional Dendritic Cells through the Myeloid Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Unique Structural Determinants for Stat3 Recruitment and Activation by the Granulocyte Colony-Stimulating Factor Receptor at Phosphotyrosine Ligands 704 and 744 ¹

Huang Shao; Xuejun Xu; Naijie Jing; David J. Tweardy

J Immunol (2006) 176 (5): 2933–2941.

Abstract

View articletitled, Unique Structural Determinants for Stat3 Recruitment and Activation by the Granulocyte Colony-Stimulating Factor Receptor at Phosphotyrosine Ligands 704 and 744<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lack of Tyrosine 320 Impairs Spontaneous Endocytosis and Enhances Release of HLA-B27 Molecules

Susana G. Santos; Antony N. Antoniou; Paula Sampaio; Simon J. Powis; Fernando A. Arosa

J Immunol (2006) 176 (5): 2942–2949.

Abstract

View articletitled, Lack of Tyrosine 320 Impairs Spontaneous Endocytosis and Enhances Release of HLA-B27 Molecules

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Evidence That Complement Protein C1q Interacts with C-Reactive Protein through Its Globular Head Region ¹

Fabian D. G. McGrath; Mieke C. Brouwer; Gérard J. Arlaud; Mohamed R. Daha; C. Erik Hack; Anja Roos

J Immunol (2006) 176 (5): 2950–2957.

Abstract

View articletitled, Evidence That Complement Protein C1q Interacts with C-Reactive Protein through Its Globular Head Region<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Amino-Terminal Flanking Residues Determine the Conformation of a Peptide–Class II MHC Complex ¹

Scott B. Lovitch; Zheng Pu; Emil R. Unanue

J Immunol (2006) 176 (5): 2958–2968.

Abstract

View articletitled, Amino-Terminal Flanking Residues Determine the Conformation of a Peptide–Class II MHC Complex<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Pituitary Adenylate Cyclase-Activating Polypeptide 27 Is a Functional Ligand for Formyl Peptide Receptor-Like 1 ¹

Youndong Kim; Byoung Dae Lee; Oekyung Kim; Yoe-Sik Bae; Taehoon Lee; Pann-Ghill Suh; Sung Ho Ryu

J Immunol (2006) 176 (5): 2969–2975.

Abstract

View articletitled, Pituitary Adenylate Cyclase-Activating Polypeptide 27 Is a Functional Ligand for Formyl Peptide Receptor-Like 1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IMMUNOGENETICS

Molecular Genetic Analysis of the Idd4 Locus Implicates the IFN Response in Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice ¹

Evgueni A. Ivakine; Omid M. Gulban; Steven M. Mortin-Toth; Ellen Wankiewicz; Christopher Scott; David Spurrell; Angelo Canty; Jayne S. Danska

J Immunol (2006) 176 (5): 2976–2990.

Abstract

View articletitled, Molecular Genetic Analysis of the Idd4 Locus Implicates the IFN Response in Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evidence for Epigenetic Maintenance of Ly49a Monoallelic Gene Expression ¹

Arefeh Rouhi; Liane Gagnier; Fumio Takei; Dixie L. Mager

J Immunol (2006) 176 (5): 2991–2999.

Abstract

View articletitled, Evidence for Epigenetic Maintenance of Ly49a Monoallelic Gene Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Expression of B7-H1 on Gastric Epithelial Cells: Its Potential Role in Regulating T Cells during Helicobacter pylori Infection ¹

Soumita Das; Giovanni Suarez; Ellen J. Beswick; Johanna C. Sierra; David Y. Graham; Victor E. Reyes

J Immunol (2006) 176 (5): 3000–3009.

Abstract

View articletitled, Expression of B7-H1 on Gastric Epithelial Cells: Its Potential Role in Regulating T Cells during Helicobacter pylori Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Myobacterium tuberculosis Induces Selective Up-Regulation of TLRs in the Mononuclear Leukocytes of Patients with Active Pulmonary Tuberculosis ¹

Jung-Su Chang; Jim F. Huggett; Keertan Dheda; Louise U. Kim; Alimuddin Zumla; Graham A. W. Rook

J Immunol (2006) 176 (5): 3010–3018.

Abstract

View articletitled, Myobacterium tuberculosis Induces Selective Up-Regulation of TLRs in the Mononuclear Leukocytes of Patients with Active Pulmonary Tuberculosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Potent Inhibition of Macrophage Responses to IFN-γ by Live Virulent Mycobacterium tuberculosis Is Independent of Mature Mycobacterial Lipoproteins but Dependent on TLR2 ¹

Niaz Banaiee; Eleanor Z. Kincaid; Ulrike Buchwald; William R. Jacobs, Jr.; Joel D. Ernst

J Immunol (2006) 176 (5): 3019–3027.

Abstract

View articletitled, Potent Inhibition of Macrophage Responses to IFN-γ by Live Virulent Mycobacterium tuberculosis Is Independent of Mature Mycobacterial Lipoproteins but Dependent on TLR2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Precursor Frequency, Nonlinear Proliferation, and Functional Maturation of Virus-Specific CD4⁺ T Cells ¹

Jason K. Whitmire; Nicola Benning; J. Lindsay Whitton

J Immunol (2006) 176 (5): 3028–3036.

Abstract

View articletitled, Precursor Frequency, Nonlinear Proliferation, and Functional Maturation of Virus-Specific CD4+ T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Clonal Competition Inhibits the Proliferation and Differentiation of Adoptively Transferred TCR Transgenic CD4 T Cells in Response to Infection ¹

Kathryn E. Foulds; Hao Shen

J Immunol (2006) 176 (5): 3037–3043.

Abstract

View articletitled, Clonal Competition Inhibits the Proliferation and Differentiation of Adoptively Transferred TCR Transgenic CD4 T Cells in Response to Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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An Antimicrobial Cathelicidin Peptide, Human CAP18/LL-37, Suppresses Neutrophil Apoptosis via the Activation of Formyl-Peptide Receptor-Like 1 and P2X₇ ¹

Isao Nagaoka; Hiroshi Tamura; Michimasa Hirata

J Immunol (2006) 176 (5): 3044–3052.

Abstract

View articletitled, An Antimicrobial Cathelicidin Peptide, Human CAP18/LL-37, Suppresses Neutrophil Apoptosis via the Activation of Formyl-Peptide Receptor-Like 1 and P2X7<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cryptococcus neoformans Glycoantigens Are Captured by Multiple Lectin Receptors and Presented by Dendritic Cells ¹

Michael K. Mansour; Eicke Latz; Stuart M. Levitz

J Immunol (2006) 176 (5): 3053–3061.

Abstract

View articletitled, Cryptococcus neoformans Glycoantigens Are Captured by Multiple Lectin Receptors and Presented by Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vaccine-Induced Memory CD8⁺ T Cells Cannot Prevent Central Nervous System Virus Reactivation ¹

Chandran Ramakrishna; Roscoe A. Atkinson; Stephen A. Stohlman; Cornelia C. Bergmann

J Immunol (2006) 176 (5): 3062–3069.

Abstract

View articletitled, Vaccine-Induced Memory CD8+ T Cells Cannot Prevent Central Nervous System Virus Reactivation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Enterocyte TLR4 Mediates Phagocytosis and Translocation of Bacteria Across the Intestinal Barrier

Matthew D. Neal; Cynthia Leaphart; Ryan Levy; Jose Prince; Timothy R. Billiar; Simon Watkins; Jun Li; Selma Cetin; Henri Ford; Alan Schreiber; David J. Hackam

J Immunol (2006) 176 (5): 3070–3079.

Abstract

View articletitled, Enterocyte TLR4 Mediates Phagocytosis and Translocation of Bacteria Across the Intestinal Barrier

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Antigen-Specific Responses Accelerate Bacterial Clearance in the Bladder ¹

Praveen Thumbikat; Carl Waltenbaugh; Anthony J. Schaeffer; David J. Klumpp

J Immunol (2006) 176 (5): 3080–3086.

Abstract

View articletitled, Antigen-Specific Responses Accelerate Bacterial Clearance in the Bladder<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Mycobacterium bovis Bacillus Calmette-Guérin Induces TLR2-Mediated Formation of Lipid Bodies: Intracellular Domains for Eicosanoid Synthesis In Vivo ¹

Heloisa D’Avila; Rossana C. N. Melo; Gleydes G. Parreira; Eduardo Werneck-Barroso; Hugo C. Castro-Faria-Neto; Patrícia T. Bozza

J Immunol (2006) 176 (5): 3087–3097.

Abstract

View articletitled, Mycobacterium bovis Bacillus Calmette-Guérin Induces TLR2-Mediated Formation of Lipid Bodies: Intracellular Domains for Eicosanoid Synthesis In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Vascular Endothelial Growth Factor-Induced Signaling Pathways in Endothelial Cells That Mediate Overexpression of the Chemokine IFN-γ-Inducible Protein of 10 kDa In Vitro and In Vivo ¹

Gwénola Boulday; Zdenka Haskova; Marlies E. J. Reinders; Soumitro Pal; David M. Briscoe

J Immunol (2006) 176 (5): 3098–3107.

Abstract

View articletitled, Vascular Endothelial Growth Factor-Induced Signaling Pathways in Endothelial Cells That Mediate Overexpression of the Chemokine IFN-γ-Inducible Protein of 10 kDa In Vitro and In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Renal Ischemia-Reperfusion Injury and Adenosine 2A Receptor-Mediated Tissue Protection: The Role of CD4⁺ T Cells and IFN-γ ¹

Yuan-Ji Day; Liping Huang; Hong Ye; Li Li; Joel Linden; Mark D. Okusa

J Immunol (2006) 176 (5): 3108–3114.

Abstract

View articletitled, Renal Ischemia-Reperfusion Injury and Adenosine 2A Receptor-Mediated Tissue Protection: The Role of CD4+ T Cells and IFN-γ<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Exacerbation of Experimental Autoimmune Encephalomyelitis in P2X₇R^−/− Mice: Evidence for Loss of Apoptotic Activity in Lymphocytes ¹

Lanfen Chen; Celia F. Brosnan

J Immunol (2006) 176 (5): 3115–3126.

Abstract

View articletitled, Exacerbation of Experimental Autoimmune Encephalomyelitis in P2X7R−/− Mice: Evidence for Loss of Apoptotic Activity in Lymphocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Acetyl-11-Keto-β-Boswellic Acid Potentiates Apoptosis, Inhibits Invasion, and Abolishes Osteoclastogenesis by Suppressing NF-κB and NF-κB-Regulated Gene Expression ¹

Yasunari Takada; Haruyo Ichikawa; Vladimir Badmaev; Bharat B. Aggarwal

J Immunol (2006) 176 (5): 3127–3140.

Abstract

View articletitled, Acetyl-11-Keto-β-Boswellic Acid Potentiates Apoptosis, Inhibits Invasion, and Abolishes Osteoclastogenesis by Suppressing NF-κB and NF-κB-Regulated Gene Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Human Specific CCR1 Antagonist CP-481,715 Inhibits Cell Infiltration and Inflammatory Responses in Human CCR1 Transgenic Mice

Ronald P. Gladue; Susan H. Cole; Marsha L. Roach; Laurie A. Tylaska; Robin T. Nelson; Richard M. Shepard; John D. McNeish; Kevin T. Ogborne; Kuldeep S. Neote

J Immunol (2006) 176 (5): 3141–3148.

Abstract

View articletitled, The Human Specific CCR1 Antagonist CP-481,715 Inhibits Cell Infiltration and Inflammatory Responses in Human CCR1 Transgenic Mice

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Ligation of the FcRγ Chain-Associated Human Osteoclast-Associated Receptor Enhances the Proinflammatory Responses of Human Monocytes and Neutrophils ¹

Estelle Merck; Claude Gaillard; Mathieu Scuiller; Patrizia Scapini; Marco A. Cassatella; Giorgio Trinchieri; Elizabeth E. M. Bates

J Immunol (2006) 176 (5): 3149–3156.

Abstract

View articletitled, Ligation of the FcRγ Chain-Associated Human Osteoclast-Associated Receptor Enhances the Proinflammatory Responses of Human Monocytes and Neutrophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Leukotriene B4 Receptor (BLT1) Is Required for Effector CD8⁺ T Cell-Mediated, Mast Cell-Dependent Airway Hyperresponsiveness ¹

Christian Taube; Nobuaki Miyahara; Vanessa Ott; Brad Swanson; Katsuyuki Takeda; Joan Loader; Leonard D. Shultz; Andrew M. Tager; Andrew D. Luster; Azzeddine Dakhama; Erwin W. Gelfand

J Immunol (2006) 176 (5): 3157–3164.

Abstract

View articletitled, The Leukotriene B4 Receptor (BLT1) Is Required for Effector CD8+ T Cell-Mediated, Mast Cell-Dependent Airway Hyperresponsiveness<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The B12 Anti-Tryptase Monoclonal Antibody Disrupts the Tetrameric Structure of Heparin-Stabilized β-Tryptase to Form Monomers That Are Inactive at Neutral pH and Active at Acidic pH ¹

Yoshihiro Fukuoka; Lawrence B. Schwartz

J Immunol (2006) 176 (5): 3165–3172.

Abstract

View articletitled, The B12 Anti-Tryptase Monoclonal Antibody Disrupts the Tetrameric Structure of Heparin-Stabilized β-Tryptase to Form Monomers That Are Inactive at Neutral pH and Active at Acidic pH<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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C5b-9 Terminal Complex Protects Oligodendrocytes from Apoptotic Cell Death by Inhibiting Caspase-8 Processing and Up-Regulating FLIP ¹

Cornelia Cudrici; Florin Niculescu; Timothy Jensen; Ekaterina Zafranskaia; Matthew Fosbrink; Violeta Rus; Moon L. Shin; Horea Rus

J Immunol (2006) 176 (5): 3173–3180.

Abstract

View articletitled, C5b-9 Terminal Complex Protects Oligodendrocytes from Apoptotic Cell Death by Inhibiting Caspase-8 Processing and Up-Regulating FLIP<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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c-Jun Kinase Is a Critical Signaling Molecule in a Neonatal Model of Group B Streptococcal Sepsis ¹

Sybille Kenzel; Guiseppe Mancuso; Richard Malley; Guiseppe Teti; Douglas T. Golenbock; Philipp Henneke

J Immunol (2006) 176 (5): 3181–3188.

Abstract

View articletitled, c-Jun Kinase Is a Critical Signaling Molecule in a Neonatal Model of Group B Streptococcal Sepsis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Pulmonary Lipopolysaccharide (LPS)-Binding Protein Inhibits the LPS-Induced Lung Inflammation In Vivo ¹

Sylvia Knapp; Sandrine Florquin; Douglas T. Golenbock; Tom van der Poll

J Immunol (2006) 176 (5): 3189–3195.

Abstract

View articletitled, Pulmonary Lipopolysaccharide (LPS)-Binding Protein Inhibits the LPS-Induced Lung Inflammation In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Fibulin-4 Is a Target of Autoimmunity Predominantly in Patients with Osteoarthritis ¹

Yang Xiang; Taichi Sekine; Hiroshi Nakamura; Shinobu Imajoh-Ohmi; Hiroyuki Fukuda; Kazuo Yudoh; Kayo Masuko-Hongo; Kusuki Nishioka; Tomohiro Kato

J Immunol (2006) 176 (5): 3196–3204.

Abstract

View articletitled, Fibulin-4 Is a Target of Autoimmunity Predominantly in Patients with Osteoarthritis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Trophoblast Contact Deactivates Human Neutrophils ¹

Howard R. Petty; Andrei L. Kindzelskii; Jimmy Espinoza; Roberto Romero

J Immunol (2006) 176 (5): 3205–3214.

Abstract

View articletitled, Trophoblast Contact Deactivates Human Neutrophils<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of the Transcription Factor Foxp3 Converts Desmoglein 3-Specific Type 1 Regulatory T Cells into Th2-Like Cells ¹

Christian Veldman; Andreas Pahl; Stefan Beissert; Wiebke Hansen; Jan Buer; Detlef Dieckmann; Gerold Schuler; Michael Hertl

J Immunol (2006) 176 (5): 3215–3222.

Abstract

View articletitled, Inhibition of the Transcription Factor Foxp3 Converts Desmoglein 3-Specific Type 1 Regulatory T Cells into Th2-Like Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Visualization of p53_264–272/HLA-A*0201 Complexes Naturally Presented on Tumor Cell Surface by a Multimeric Soluble Single-Chain T Cell Receptor ¹

Xiaoyun Zhu; Heather J. Belmont; Shari Price-Schiavi; Bai Liu; Hyung-il Lee; Marilyn Fernandez; Richard L. Wong; Janette Builes; Peter R. Rhode; Hing C. Wong

J Immunol (2006) 176 (5): 3223–3232.

Abstract

View articletitled, Visualization of p53264–272/HLA-A*0201 Complexes Naturally Presented on Tumor Cell Surface by a Multimeric Soluble Single-Chain T Cell Receptor<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Lupus-Susceptibility Locus, Sle3, Mediates Enhanced Resistance to Bacterial Infections ¹

Borna Mehrad; Stacy J. Park; Gangaram Akangire; Theodore J. Standiford; Tianfu Wu; Jiankun Zhu; Chandra Mohan

J Immunol (2006) 176 (5): 3233–3239.

Abstract

View articletitled, The Lupus-Susceptibility Locus, Sle3, Mediates Enhanced Resistance to Bacterial Infections<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Contribution of NZB Autoimmunity 2 to Y-Linked Autoimmune Acceleration-Induced Monocytosis in Association with Murine Systemic Lupus ¹

Shuichi Kikuchi; Marie-Laure Santiago-Raber; Hirofumi Amano; Eri Amano; Liliane Fossati-Jimack; Thomas Moll; Brian L. Kotzin; Shozo Izui

J Immunol (2006) 176 (5): 3240–3247.

Abstract

View articletitled, Contribution of NZB Autoimmunity 2 to Y-Linked Autoimmune Acceleration-Induced Monocytosis in Association with Murine Systemic Lupus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulatory Networks Induced by Live Parasites Impair Both Th1 and Th2 Pathways in Patent Lymphatic Filariasis: Implications for Parasite Persistence ¹

Subash Babu; Carla P. Blauvelt; V. Kumaraswami; Thomas B. Nutman

J Immunol (2006) 176 (5): 3248–3256.

Abstract

View articletitled, Regulatory Networks Induced by Live Parasites Impair Both Th1 and Th2 Pathways in Patent Lymphatic Filariasis: Implications for Parasite Persistence<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HLA-A*0201-Restricted T Cells from Humanized NOD Mice Recognize Autoantigens of Potential Clinical Relevance to Type 1 Diabetes ¹

Toshiyuki Takaki; Michele P. Marron; Clayton E. Mathews; Stephen T. Guttmann; Rita Bottino; Massimo Trucco; Teresa P. DiLorenzo; David V. Serreze

J Immunol (2006) 176 (5): 3257–3265.

Abstract

View articletitled, HLA-A*0201-Restricted T Cells from Humanized NOD Mice Recognize Autoantigens of Potential Clinical Relevance to Type 1 Diabetes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evidence to Support the Role of HLA-G5 in Allograft Acceptance through Induction of Immunosuppressive/ Regulatory T Cells ¹

Solène Le Rond; Christine Azéma; Irène Krawice-Radanne; Antoine Durrbach; Catherine Guettier; Edgardo D. Carosella; Nathalie Rouas-Freiss

J Immunol (2006) 176 (5): 3266–3276.

Abstract

View articletitled, Evidence to Support the Role of HLA-G5 in Allograft Acceptance through Induction of Immunosuppressive/ Regulatory T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

IN THIS ISSUE

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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