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J Immunol (2006) 176 (6): 3289–3290.

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BRIEF REVIEWS

Mechanisms of Immunopathology in Murine Models of Central Nervous System Demyelinating Disease ¹

Anne M. Ercolini; Stephen D. Miller

J Immunol (2006) 176 (6): 3293–3298.

Abstract

View articletitled, Mechanisms of Immunopathology in Murine Models of Central Nervous System Demyelinating Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CUTTING EDGE

Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4⁺CD25⁺ T Regulatory Cells ¹

Adam P. Kohm; Jeffrey S. McMahon; Joseph R. Podojil; Wendy Smith Begolka; Mathew DeGutes; Deborah J. Kasprowicz; Steven F. Ziegler; Stephen D. Miller

J Immunol (2006) 176 (6): 3301–3305.

Abstract

View articletitled, Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4+CD25+ T Regulatory Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: CD28 Controls Dominant Regulatory T Cell Activity during Active Immunization ¹

Clay Lyddane; Beata U. Gajewska; Elmer Santos; Philip D. King; Glaucia C. Furtado; Michel Sadelain

J Immunol (2006) 176 (6): 3306–3310.

Abstract

View articletitled, Cutting Edge: CD28 Controls Dominant Regulatory T Cell Activity during Active Immunization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Hormonal Milieu, Not Antigenic Specificity, Determines the Mature Phenotype of Autoreactive B Cells ¹

Jeganathan Venkatesh; Elena Peeva; Xiaonan Xu; Betty Diamond

J Immunol (2006) 176 (6): 3311–3314.

Abstract

View articletitled, Cutting Edge: Hormonal Milieu, Not Antigenic Specificity, Determines the Mature Phenotype of Autoreactive B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: The Direct Action of Type I IFN on CD4 T Cells Is Critical for Sustaining Clonal Expansion in Response to a Viral but Not a Bacterial Infection ¹

Colin Havenar-Daughton; Ganesh A. Kolumam; Kaja Murali-Krishna

J Immunol (2006) 176 (6): 3315–3319.

Abstract

View articletitled, Cutting Edge: The Direct Action of Type I IFN on CD4 T Cells Is Critical for Sustaining Clonal Expansion in Response to a Viral but Not a Bacterial Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

TGF-β Requires CTLA-4 Early after T Cell Activation to Induce FoxP3 and Generate Adaptive CD4⁺CD25⁺ Regulatory Cells ¹

Song Guo Zheng; Ju Hua Wang; William Stohl; Kyoung Soo Kim; J. Dixon Gray; David A. Horwitz

J Immunol (2006) 176 (6): 3321–3329.

Abstract

View articletitled, TGF-β Requires CTLA-4 Early after T Cell Activation to Induce FoxP3 and Generate Adaptive CD4+CD25+ Regulatory Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dendritic Cell Synthesis of C3 Is Required for Full T Cell Activation and Development of a Th1 Phenotype ¹

Qi Peng; Ke Li; Hetal Patel; Steven H. Sacks; Wuding Zhou

J Immunol (2006) 176 (6): 3330–3341.

Abstract

View articletitled, Dendritic Cell Synthesis of C3 Is Required for Full T Cell Activation and Development of a Th1 Phenotype<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vitro Suppression of CD8⁺ T Cell Function by Friend Virus-Induced Regulatory T Cells ¹

Shelly J. Robertson; Ronald J. Messer; Aaron B. Carmody; Kim J. Hasenkrug

J Immunol (2006) 176 (6): 3342–3349.

Abstract

View articletitled, In Vitro Suppression of CD8+ T Cell Function by Friend Virus-Induced Regulatory T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Attenuation of IL-7 Receptor Signaling Is Not Required for Allelic Exclusion ¹

Wynette M. Will; Joshua D. Aaker; Matthew A. Burchill; Ian R. Harmon; Jennifer J. O’Neil; Christine A. Goetz; Keli L. Hippen; Michael A. Farrar

J Immunol (2006) 176 (6): 3350–3355.

Abstract

View articletitled, Attenuation of IL-7 Receptor Signaling Is Not Required for Allelic Exclusion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Soluble MHC-Peptide Complexes Containing Long Rigid Linkers Abolish CTL-Mediated Cytotoxicity ¹

Georgi S. Angelov; Philippe Guillaume; Marek Cebecauer; Giovanna Bosshard; Danijel Dojcinovic; Petra Baumgaertner; Immanuel F. Luescher

J Immunol (2006) 176 (6): 3356–3365.

Abstract

View articletitled, Soluble MHC-Peptide Complexes Containing Long Rigid Linkers Abolish CTL-Mediated Cytotoxicity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Loss of the Surface Antigen 3G11 Characterizes a Distinct Population of Anergic/Regulatory T Cells in Experimental Autoimmune Encephalomyelitis ¹

Guang-Xian Zhang; Shuo Yu; Divina Calida; Zhao Zhao; Bruno Gran; Malek Kamoun; Abdolmohamad Rostami

J Immunol (2006) 176 (6): 3366–3373.

Abstract

View articletitled, Loss of the Surface Antigen 3G11 Characterizes a Distinct Population of Anergic/Regulatory T Cells in Experimental Autoimmune Encephalomyelitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CTL Adoptive Immunotherapy Concurrently Mediates Tumor Regression and Tumor Escape

Kebin Liu; Sheila A. Caldwell; Kristy M. Greeneltch; Dafeng Yang; Scott I. Abrams

J Immunol (2006) 176 (6): 3374–3382.

Abstract

View articletitled, CTL Adoptive Immunotherapy Concurrently Mediates Tumor Regression and Tumor Escape

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Alloantigen Affinity and CD4 Help Determine Severity of Graft-versus-Host Disease Mediated by CD8 Donor T Cells ¹

Xue-Zhong Yu; Michael H. Albert; Claudio Anasetti

J Immunol (2006) 176 (6): 3383–3390.

Abstract

View articletitled, Alloantigen Affinity and CD4 Help Determine Severity of Graft-versus-Host Disease Mediated by CD8 Donor T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The BZLF1 Homolog of an Epstein-Barr-Related γ-Herpesvirus Is a Frequent Target of the CTL Response in Persistently Infected Rhesus Macaques ¹

Mark H. Fogg; Deirdre Garry; Amany Awad; Fred Wang; Amitinder Kaur

J Immunol (2006) 176 (6): 3391–3401.

Abstract

View articletitled, The BZLF1 Homolog of an Epstein-Barr-Related γ-Herpesvirus Is a Frequent Target of the CTL Response in Persistently Infected Rhesus Macaques<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of Antigen-Processing Machinery in the In Vitro Resistance of Squamous Cell Carcinoma of the Head and Neck Cells to Recognition by CTL ¹

Andrés López-Albaitero; Jayakar V. Nayak; Takeshi Ogino; Avinash Machandia; William Gooding; Albert B. DeLeo; Soldano Ferrone; Robert L. Ferris

J Immunol (2006) 176 (6): 3402–3409.

Abstract

View articletitled, Role of Antigen-Processing Machinery in the In Vitro Resistance of Squamous Cell Carcinoma of the Head and Neck Cells to Recognition by CTL<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Alloreactive CD4 T Cell Tolerance in Molecular Chimeras: A Possible Role for Regulatory T Cells ¹

Daron Forman; Eun-Suk Kang; Chaorui Tian; Jesus Paez-Cortez; John Iacomini

J Immunol (2006) 176 (6): 3410–3416.

Abstract

View articletitled, Induction of Alloreactive CD4 T Cell Tolerance in Molecular Chimeras: A Possible Role for Regulatory T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Combinations of CD45 Isoforms Are Crucial for Immune Function and Disease

Ritu Dawes; Svetla Petrova; Zhe Liu; David Wraith; Peter C. L. Beverley; Elma Z. Tchilian

J Immunol (2006) 176 (6): 3417–3425.

Abstract

View articletitled, Combinations of CD45 Isoforms Are Crucial for Immune Function and Disease

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Immunization with Murine Breast Cancer Cells Treated with Antisense Oligodeoxynucleotides to Type I Insulin-Like Growth Factor Receptor Induced an Antitumoral Effect Mediated by a CD8⁺ Response Involving Fas/Fas Ligand Cytotoxic Pathway ¹

Roxana Schillaci; Mariana Salatino; Juliana Cassataro; Cecilia J. Proietti; Guillermo H. Giambartolomei; Martín A. Rivas; Romina P. Carnevale; Eduardo H. Charreau; Patricia V. Elizalde

J Immunol (2006) 176 (6): 3426–3437.

Abstract

View articletitled, Immunization with Murine Breast Cancer Cells Treated with Antisense Oligodeoxynucleotides to Type I Insulin-Like Growth Factor Receptor Induced an Antitumoral Effect Mediated by a CD8+ Response Involving Fas/Fas Ligand Cytotoxic Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential MHC Class II Presentation of a Pathogenic Autoantigen during Health and Disease ¹

Fei F. Shih; Jennifer Racz; Paul M. Allen

J Immunol (2006) 176 (6): 3438–3448.

Abstract

View articletitled, Differential MHC Class II Presentation of a Pathogenic Autoantigen during Health and Disease<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulatory T Cells Can Mediate Their Function through the Stimulation of APCs to Produce Immunosuppressive Nitric Oxide ¹

Cyndi Chen; Wen-hui Lee; Lingwen Zhong; Chih-Pin Liu

J Immunol (2006) 176 (6): 3449–3460.

Abstract

View articletitled, Regulatory T Cells Can Mediate Their Function through the Stimulation of APCs to Produce Immunosuppressive Nitric Oxide<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Superior Protective and Therapeutic Effects of IL-12 and IL-18 Gene-Transduced Dendritic Neuroblastoma Fusion Cells on Liver Metastasis of Murine Neuroblastoma ¹

Hisae Iinuma; Kota Okinaga; Ryoji Fukushima; Tsuyoshi Inaba; Kota Iwasaki; Akira Okinaga; Ichiro Takahashi; Michio Kaneko

J Immunol (2006) 176 (6): 3461–3469.

Abstract

View articletitled, Superior Protective and Therapeutic Effects of IL-12 and IL-18 Gene-Transduced Dendritic Neuroblastoma Fusion Cells on Liver Metastasis of Murine Neuroblastoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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GATA-3 Directly Remodels the IL-10 Locus Independently of IL-4 in CD4⁺ T Cells

John Shoemaker; Margarida Saraiva; Anne O’Garra

J Immunol (2006) 176 (6): 3470–3479.

Abstract

View articletitled, GATA-3 Directly Remodels the IL-10 Locus Independently of IL-4 in CD4+ T Cells

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Differential Role of Programmed Death-Ligand 1 and Programmed Death-Ligand 2 in Regulating the Susceptibility and Chronic Progression of Experimental Autoimmune Encephalomyelitis ¹

Bing Zhu; Indira Guleria; Arezou Khosroshahi; Tanuja Chitnis; Jaime Imitola; Miyuki Azuma; Hideo Yagita; Mohamed H. Sayegh; Samia J. Khoury

J Immunol (2006) 176 (6): 3480–3489.

Abstract

View articletitled, Differential Role of Programmed Death-Ligand 1 and Programmed Death-Ligand 2 in Regulating the Susceptibility and Chronic Progression of Experimental Autoimmune Encephalomyelitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Overexpression of Cellular Prion Protein Induces an Antioxidant Environment Altering T Cell Development in the Thymus ¹

Evelyne Jouvin-Marche; Valérie Attuil-Audenis; Catherine Aude-Garcia; Walid Rachidi; Mark Zabel; Valérie Podevin-Dimster; Carole Siret; Christoph Huber; Marianne Martinic; Jacqueline Riondel; Christian L. Villiers; Alain Favier; Philippe Naquet; Jean-Yves Cesbron; Patrice N. Marche

J Immunol (2006) 176 (6): 3490–3497.

Abstract

View articletitled, Overexpression of Cellular Prion Protein Induces an Antioxidant Environment Altering T Cell Development in the Thymus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Primary T Cell Expansion and Differentiation In Vivo Requires Antigen Presentation by B Cells ¹

Alison Crawford; Megan MacLeod; Ton Schumacher; Louise Corlett; David Gray

J Immunol (2006) 176 (6): 3498–3506.

Abstract

View articletitled, Primary T Cell Expansion and Differentiation In Vivo Requires Antigen Presentation by B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Engagement of Glucocorticoid-Induced TNF Receptor Costimulates NKT Cell Activation In Vitro and In Vivo ¹

Hyun Jung Kim; Hye Young Kim; Byoung Kwon Kim; Sanghee Kim; Doo Hyun Chung

J Immunol (2006) 176 (6): 3507–3515.

Abstract

View articletitled, Engagement of Glucocorticoid-Induced TNF Receptor Costimulates NKT Cell Activation In Vitro and In Vivo<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Complement Receptor 1 and 2 Deficiency Increases Coxsackievirus B3-Induced Myocarditis, Dilated Cardiomyopathy, and Heart Failure by Increasing Macrophages, IL-1β, and Immune Complex Deposition in the Heart ¹

DeLisa Fairweather; Sylvia Frisancho-Kiss; Dolores B. Njoku; Jennifer F. Nyland; Ziya Kaya; Susy A. Yusung; Sarah E. Davis; J. Augusto Frisancho; Masheka A. Barrett; Noel R. Rose

J Immunol (2006) 176 (6): 3516–3524.

Abstract

View articletitled, Complement Receptor 1 and 2 Deficiency Increases Coxsackievirus B3-Induced Myocarditis, Dilated Cardiomyopathy, and Heart Failure by Increasing Macrophages, IL-1β, and Immune Complex Deposition in the Heart<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distinct Subsets of Dendritic Cells Regulate the Pattern of Acute Xenograft Rejection and Susceptibility to Cyclosporine Therapy ¹

Hao Wang; Jacqueline Arp; Xuyan Huang; Weihua Liu; Siobhan Ramcharran; Jifu Jiang; Bertha Garcia; Nobuyuki Kanai; Weiping Min; Peta J. O’Connell; Robert Zhong

J Immunol (2006) 176 (6): 3525–3535.

Abstract

View articletitled, Distinct Subsets of Dendritic Cells Regulate the Pattern of Acute Xenograft Rejection and Susceptibility to Cyclosporine Therapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Human Dendritic Cell Expression of HLA-DO Is Subset Specific and Regulated by Maturation ¹

Tara M. C. Hornell; Timo Burster; Frode L. Jahnsen; Achal Pashine; Maria T. Ochoa; James J. Harding; Claudia Macaubas; Andrew W. Lee; Robert L. Modlin; Elizabeth D. Mellins

J Immunol (2006) 176 (6): 3536–3547.

Abstract

View articletitled, Human Dendritic Cell Expression of HLA-DO Is Subset Specific and Regulated by Maturation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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H2-O Expression in Primary Dendritic Cells ¹

Xinjian Chen; Lisa M. Reed-Loisel; Lars Karlsson; Peter E. Jensen

J Immunol (2006) 176 (6): 3548–3556.

Abstract

View articletitled, H2-O Expression in Primary Dendritic Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-4 and IL-13 Form a Negative Feedback Circuit with Surfactant Protein-D in the Allergic Airway Response ¹

Angela Haczku; Yang Cao; Geza Vass; Sonja Kierstein; Puneeta Nath; Elena N. Atochina-Vasserman; Seth T. Scanlon; Lily Li; Don E. Griswold; K. Fan Chung; Francis R. Poulain; Samuel Hawgood; Michael F. Beers; Erika C. Crouch

J Immunol (2006) 176 (6): 3557–3565.

Abstract

View articletitled, IL-4 and IL-13 Form a Negative Feedback Circuit with Surfactant Protein-D in the Allergic Airway Response<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fms-Like Tyrosine Kinase 3 Ligand Recruits Plasmacytoid Dendritic Cells to the Brain ¹

James F. Curtin; Gwendalyn D. King; Carlos Barcia; Chunyan Liu; François X. Hubert; Carole Guillonneau; Régis Josien; Ignacio Anegon; Pedro R. Lowenstein; Maria G. Castro

J Immunol (2006) 176 (6): 3566–3577.

Abstract

View articletitled, Fms-Like Tyrosine Kinase 3 Ligand Recruits Plasmacytoid Dendritic Cells to the Brain<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Dendritic Cell Trafficking to and from the Airways

Claudia Jakubzick; Frank Tacke; Jaime Llodra; Nico van Rooijen; Gwendalyn J. Randolph

J Immunol (2006) 176 (6): 3578–3584.

Abstract

View articletitled, Modulation of Dendritic Cell Trafficking to and from the Airways

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Placenta-Derived Soluble MHC Class I Chain-Related Molecules Down-Regulate NKG2D Receptor on Peripheral Blood Mononuclear Cells during Human Pregnancy: A Possible Novel Immune Escape Mechanism for Fetal Survival ¹

Lucia Mincheva-Nilsson; Olga Nagaeva; Ting Chen; Ulf Stendahl; Julia Antsiferova; Ingrid Mogren; Jenny Hernestål; Vladimir Baranov

J Immunol (2006) 176 (6): 3585–3592.

Abstract

View articletitled, Placenta-Derived Soluble MHC Class I Chain-Related Molecules Down-Regulate NKG2D Receptor on Peripheral Blood Mononuclear Cells during Human Pregnancy: A Possible Novel Immune Escape Mechanism for Fetal Survival<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Molecular Mechanisms Underlying FOXP3 Induction in Human T Cells ¹

Pierre-Yves Mantel; Nadia Ouaked; Beate Rückert; Christian Karagiannidis; Roland Welz; Kurt Blaser; Carsten B. Schmidt-Weber

J Immunol (2006) 176 (6): 3593–3602.

Abstract

View articletitled, Molecular Mechanisms Underlying FOXP3 Induction in Human T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Signaling through Mutants of the IgA Receptor CD89 and Consequences for Fc Receptor γ-Chain Interaction ¹

Jantine E. Bakema; Simone de Haij; Constance F. den Hartog-Jager; Johanna Bakker; Gestur Vidarsson; Marjolein van Egmond; Jan G. J. van de Winkel; Jeanette H. W. Leusen

J Immunol (2006) 176 (6): 3603–3610.

Abstract

View articletitled, Signaling through Mutants of the IgA Receptor CD89 and Consequences for Fc Receptor γ-Chain Interaction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The γ-Parvin-Integrin-Linked Kinase Complex Is Critically Involved in Leukocyte-Substrate Interaction ¹

Ryusuke Yoshimi; Satoshi Yamaji; Atsushi Suzuki; Wataru Mishima; Mayumi Okamura; Takashi Obana; Chie Matsuda; Yoshihiro Miwa; Shigeo Ohno; Yoshiaki Ishigatsubo

J Immunol (2006) 176 (6): 3611–3624.

Abstract

View articletitled, The γ-Parvin-Integrin-Linked Kinase Complex Is Critically Involved in Leukocyte-Substrate Interaction<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors ¹

Manfred Brigl; Peter van den Elzen; Xiuxu Chen; Jennifer Hartt Meyers; Douglass Wu; Chi-Huey Wong; Faye Reddington; Petr A. Illarianov; Gurdyal S. Besra; Michael B. Brenner; Jenny E. Gumperz

J Immunol (2006) 176 (6): 3625–3634.

Abstract

View articletitled, Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Bruton’s Tyrosine Kinase Is Required for TLR2 and TLR4-Induced TNF, but Not IL-6, Production ¹

Nicole J. Horwood; Theresa H. Page; John P. McDaid; Christine D. Palmer; Jamie Campbell; Tara Mahon; Fionula M. Brennan; David Webster; Brian M. J. Foxwell

J Immunol (2006) 176 (6): 3635–3641.

Abstract

View articletitled, Bruton’s Tyrosine Kinase Is Required for TLR2 and TLR4-Induced TNF, but Not IL-6, Production<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Characterization of the CCL25 Promoter in Small Intestinal Epithelial Cells Suggests a Regulatory Role for Caudal-Related Homeobox (Cdx) Transcription Factors ¹

Anna Ericsson; Knut Kotarsky; Marcus Svensson; Mikael Sigvardsson; William Agace

J Immunol (2006) 176 (6): 3642–3651.

Abstract

View articletitled, Functional Characterization of the CCL25 Promoter in Small Intestinal Epithelial Cells Suggests a Regulatory Role for Caudal-Related Homeobox (Cdx) Transcription Factors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modification of MyD88 mRNA Splicing and Inhibition of IL-1β Signaling in Cell Culture and in Mice with a 2′-O-Methoxyethyl-Modified Oligonucleotide

Timothy A. Vickers; Hong Zhang; Mark J. Graham; Kristina M. Lemonidis; Chenguang Zhao; Nicholas M. Dean

J Immunol (2006) 176 (6): 3652–3661.

Abstract

View articletitled, Modification of MyD88 mRNA Splicing and Inhibition of IL-1β Signaling in Cell Culture and in Mice with a 2′-O-Methoxyethyl-Modified Oligonucleotide

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IMMUNOGENETICS

Genetic Dissection of Vasculitis, Myeloperoxidase-Specific Antineutrophil Cytoplasmic Autoantibody Production, and Related Traits in Spontaneous Crescentic Glomerulonephritis-Forming/Kinjoh Mice ¹

Yoshitomo Hamano; Kazuyuki Tsukamoto; Masaaki Abe; Guo Dong Sun; Danqing Zhang; Hiroaki Fujii; Shuji Matsuoka; Masumi Tanaka; Akiko Ishida-Okawara; Hitoshi Tachikawa; Hiroyuki Nishimura; Kazuhiro Tokunaka; Sachiko Hirose; Kazuo Suzuki

J Immunol (2006) 176 (6): 3662–3673.

Abstract

View articletitled, Genetic Dissection of Vasculitis, Myeloperoxidase-Specific Antineutrophil Cytoplasmic Autoantibody Production, and Related Traits in Spontaneous Crescentic Glomerulonephritis-Forming/Kinjoh Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ancestral Organization of the MHC Revealed in the Amphibian Xenopus¹

Yuko Ohta; Wilfried Goetz; M. Zulfiquer Hossain; Masaru Nonaka; Martin F. Flajnik

J Immunol (2006) 176 (6): 3674–3685.

Abstract

View articletitled, Ancestral Organization of the MHC Revealed in the Amphibian Xenopus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

Phospholipase D1 Regulates Phagocyte Adhesion ¹

Shankar S. Iyer; Reitu S. Agrawal; Christopher R. Thompson; Steven Thompson; James A. Barton; David J. Kusner

J Immunol (2006) 176 (6): 3686–3696.

Abstract

View articletitled, Phospholipase D1 Regulates Phagocyte Adhesion<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Combined CTA1-DD/ISCOM Adjuvant Vector Promotes Priming of Mucosal and Systemic Immunity to Incorporated Antigens by Specific Targeting of B Cells ¹

Anja Helgeby; Neil C. Robson; Anne M. Donachie; Helen Beackock-Sharp; Karin Lövgren; Karin Schön; Allan Mowat; Nils Y. Lycke

J Immunol (2006) 176 (6): 3697–3706.

Abstract

View articletitled, The Combined CTA1-DD/ISCOM Adjuvant Vector Promotes Priming of Mucosal and Systemic Immunity to Incorporated Antigens by Specific Targeting of B Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Mechanism of Virulence: Virulent Mycobacterium tuberculosis Strain H37Rv, but Not Attenuated H37Ra, Causes Significant Mitochondrial Inner Membrane Disruption in Macrophages Leading to Necrosis ¹

Minjian Chen; Huixian Gan; Heinz G. Remold

J Immunol (2006) 176 (6): 3707–3716.

Abstract

View articletitled, A Mechanism of Virulence: Virulent Mycobacterium tuberculosis Strain H37Rv, but Not Attenuated H37Ra, Causes Significant Mitochondrial Inner Membrane Disruption in Macrophages Leading to Necrosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Dectin-1 and TLRs Permit Macrophages to Distinguish between Different Aspergillus fumigatus Cellular States ¹

Geoffrey M. Gersuk; David M. Underhill; Liqun Zhu; Kieren A. Marr

J Immunol (2006) 176 (6): 3717–3724.

Abstract

View articletitled, Dectin-1 and TLRs Permit Macrophages to Distinguish between Different Aspergillus fumigatus Cellular States<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Structure and Regulatory Profile of the Monkeypox Inhibitor of Complement: Comparison to Homologs in Vaccinia and Variola and Evidence for Dimer Formation ¹

M. Kathryn Liszewski; Marilyn K. Leung; Richard Hauhart; R. Mark L. Buller; Paula Bertram; Xuefeng Wang; Ariella M. Rosengard; Girish J. Kotwal; John P. Atkinson

J Immunol (2006) 176 (6): 3725–3734.

Abstract

View articletitled, Structure and Regulatory Profile of the Monkeypox Inhibitor of Complement: Comparison to Homologs in Vaccinia and Variola and Evidence for Dimer Formation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Matrix Metalloproteinase-9 Deficiency Impairs Host Defense against Abdominal Sepsis ¹

Rosemarijn Renckens; Joris J. T. H. Roelofs; Sandrine Florquin; Alex F. de Vos; H. Roger Lijnen; Cornelis van’t Veer; Tom van der Poll

J Immunol (2006) 176 (6): 3735–3741.

Abstract

View articletitled, Matrix Metalloproteinase-9 Deficiency Impairs Host Defense against Abdominal Sepsis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of Neonatal Microbial Recognition: TLR-Mediated Innate Immune Responses Are Specifically and Differentially Modulated by Human Milk ¹

Emmanuel LeBouder; Julia E. Rey-Nores; Anne-Catherine Raby; Michael Affolter; Karine Vidal; Catherine A. Thornton; Mario O. Labéta

J Immunol (2006) 176 (6): 3742–3752.

Abstract

View articletitled, Modulation of Neonatal Microbial Recognition: TLR-Mediated Innate Immune Responses Are Specifically and Differentially Modulated by Human Milk<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Epitope Enhancement of a CD4 HIV Epitope toward the Development of the Next Generation HIV Vaccine ¹

Takahiro Okazaki; C. David Pendleton; Pablo Sarobe; Elaine K. Thomas; Sujatha Iyengar; Clayton Harro; David Schwartz; Jay A. Berzofsky

J Immunol (2006) 176 (6): 3753–3759.

Abstract

View articletitled, Epitope Enhancement of a CD4 HIV Epitope toward the Development of the Next Generation HIV Vaccine<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Genome-Wide Analysis Reveals a Highly Diverse CD8 T Cell Response to Murine Cytomegalovirus ¹

Michael W. Munks; Marielle C. Gold; Allison L. Zajac; Carmen M. Doom; Christopher S. Morello; Deborah H. Spector; Ann B. Hill

J Immunol (2006) 176 (6): 3760–3766.

Abstract

View articletitled, Genome-Wide Analysis Reveals a Highly Diverse CD8 T Cell Response to Murine Cytomegalovirus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

A Quantitative Trait Loci Analysis to Map Genes Involved in Lipopolysaccharide-Induced Inflammatory Response: Identification of Macrophage Scavenger Receptor 1 as a Candidate Gene ¹

William B. Fulton; Roger H. Reeves; Motohiro Takeya; Antonio De Maio

J Immunol (2006) 176 (6): 3767–3773.

Abstract

View articletitled, A Quantitative Trait Loci Analysis to Map Genes Involved in Lipopolysaccharide-Induced Inflammatory Response: Identification of Macrophage Scavenger Receptor 1 as a Candidate Gene<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Pancreatitis-Associated Protein I Suppresses NF-κB Activation through a JAK/STAT-Mediated Mechanism in Epithelial Cells ¹

Emma Folch-Puy; Susana Granell; Jean C. Dagorn; Juan L. Iovanna; Daniel Closa

J Immunol (2006) 176 (6): 3774–3779.

Abstract

View articletitled, Pancreatitis-Associated Protein I Suppresses NF-κB Activation through a JAK/STAT-Mediated Mechanism in Epithelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regulation of IL-1 Family Cytokines IL-1α, IL-1 Receptor Antagonist, and IL-18 by 1,25-Dihydroxyvitamin D₃ in Primary Keratinocytes ¹

Juan Kong; Sergei A. Grando; Yan Chun Li

J Immunol (2006) 176 (6): 3780–3787.

Abstract

View articletitled, Regulation of IL-1 Family Cytokines IL-1α, IL-1 Receptor Antagonist, and IL-18 by 1,25-Dihydroxyvitamin D3 in Primary Keratinocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mast Cell β-Tryptase Selectively Cleaves Eotaxin and RANTES and Abrogates Their Eosinophil Chemotactic Activities ¹

Linhua Pang; Mei Nie; Lisa Corbett; Amy Sutcliffe; Alan J. Knox

J Immunol (2006) 176 (6): 3788–3795.

Abstract

View articletitled, Mast Cell β-Tryptase Selectively Cleaves Eotaxin and RANTES and Abrogates Their Eosinophil Chemotactic Activities<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MyD88 and TNF Receptor-Associated Factor 6 Are Critical Signal Transducers in Helicobacter pylori-Infected Human Epithelial Cells ¹

Yoshihiro Hirata; Tomoya Ohmae; Wataru Shibata; Shin Maeda; Keiji Ogura; Haruhiko Yoshida; Takao Kawabe; Masao Omata

J Immunol (2006) 176 (6): 3796–3803.

Abstract

View articletitled, MyD88 and TNF Receptor-Associated Factor 6 Are Critical Signal Transducers in Helicobacter pylori-Infected Human Epithelial Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Microglia Recognize Double-Stranded RNA via TLR3 ¹

Terrence Town; David Jeng; Lena Alexopoulou; Jun Tan; Richard A. Flavell

J Immunol (2006) 176 (6): 3804–3812.

Abstract

View articletitled, Microglia Recognize Double-Stranded RNA via TLR3<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Preprotachykinin-A Gene Products Are Key Mediators of Lung Injury in Polymicrobial Sepsis ¹

Padmam Puneet; Akhil Hegde; Siaw Wei Ng; Hon Yen Lau; Jia Lu; Shabbir M. Moochhala; Madhav Bhatia

J Immunol (2006) 176 (6): 3813–3820.

Abstract

View articletitled, Preprotachykinin-A Gene Products Are Key Mediators of Lung Injury in Polymicrobial Sepsis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

T Cell Responses in Dengue Hemorrhagic Fever: Are Cross-Reactive T Cells Suboptimal?¹

Juthathip Mongkolsapaya; Thaneeya Duangchinda; Wanwisa Dejnirattisai; Sirijit Vasanawathana; Panisadee Avirutnan; Aroonroong Jairungsri; Nuanpan Khemnu; Nattaya Tangthawornchaikul; Pojchong Chotiyarnwong; Kanokwan Sae-Jang; Michael Koch; Yvonne Jones; Andrew McMichael; Xiaoning Xu; Prida Malasit; Gavin Screaton

J Immunol (2006) 176 (6): 3821–3829.

Abstract

View articletitled, T Cell Responses in Dengue Hemorrhagic Fever: Are Cross-Reactive T Cells Suboptimal?<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Sensitization of IL-2 Signaling through TLR-7 Enhances B Lymphoma Cell Immunogenicity ¹

Jelena Tomic; Dionne White; Yonghong Shi; Jenny Mena; Caitlin Hammond; Liwei He; Richard L. Miller; David E. Spaner

J Immunol (2006) 176 (6): 3830–3839.

Abstract

View articletitled, Sensitization of IL-2 Signaling through TLR-7 Enhances B Lymphoma Cell Immunogenicity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CORRECTIONS

IL-21 induces the functional maturation of murine NK cells.

J. Brady; Y. Hayakawa; M. J. Smyth; S. L. Nutt

J Immunol (2006) 176 (6): 3840.

View articletitled, IL-21 induces the functional maturation of murine NK cells.

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Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo.

G. V. Shurin; R. Ferris; I. L. Tourkova; L. Perez; A. Lokshin; L. Balkir; B. Collins; G. S. Chatta; M. R. Shurin

J Immunol (2006) 176 (6): 3840.

View articletitled, Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo.

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Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth.

H. C. Santiago; C. G. Feng; A. Bafica; E. Roffe; R. M. Arantes; A. Cheever; G. Taylor; L. Q. Vierira; J. Aliberti; R. T. Gazzinelli; A. Sher

J Immunol (2006) 176 (6): 3840.

View articletitled, Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth.

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Integrin α_IIbβ₃ induces the adhesion and activation of mast cells through interaction with fibrinogen.

T. Oki; J. Kitaura; K. Eto; Y. Lu; M. Maeda-Yamamoto; N. Inagaki; H. Nagai; Y. Yamanishi; H. Nakajina; H. Kumagai; T. Kitamura

J Immunol (2006) 176 (6): 3841.

View articletitled, Integrin αIIbβ3 induces the adhesion and activation of mast cells through interaction with fibrinogen.

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Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.

D. B. Graham; M. P. Bell; M. M. McCausland; C. J. Huntoon; J. van Deursen; W. A. Faubion; S. Crotty; D. J. McKean

J Immunol (2006) 176 (6): 3841.

View articletitled, Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.

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Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells.

M.-T. Tien; S. E. Girardin; B. Regnault; L. Le Bourhis; M.-A. Dillies; J.-Y. Coppée; R. Bourdet-Sicard; P. J. Sansonetti; T. Pédron

J Immunol (2006) 176 (6): 3841.

View articletitled, Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells.

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Tec kinases Itk and Rlk are required for CD8⁺ T cell responses to virus infection independent of their role in CD4⁺ T cell help.

L. O. Atherly; M. A. Brehm; R. M. Welsh; L. J. Berg

J Immunol (2006) 176 (6): 3842.

View articletitled, Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help.

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CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement.

J. D. Stone; L. J. Stern

J Immunol (2006) 176 (6): 3843.

View articletitled, CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement.

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Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes.

C. N. Serhan; K. Gotlinger; S. Hong; Y. Lu; J. Siegelman; T. Baer; R. Yang; S. P. Colgan; N. A. Petasis

J Immunol (2006) 176 (6): 3843.

View articletitled, Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes.

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Thymocyte negative selection is mediated by protein kinase C- and Ca²⁺-dependent transcriptional induction of Bim of cell death.

K. Canté-Barrett; E. M. Gallo; M. M. Winslow; G. R. Crabtree

J Immunol (2006) 176 (6): 3843.

View articletitled, Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of Bim of cell death.

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Issues

IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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