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J Immunol (2006) 176 (7): 3851–3852.

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LETTERS TO THE EDITOR

Comment on “CD226 Is Specifically Expressed on the Surface of Th1 Cells and Regulates Their Expansion and Effector Functions”

Kazuko Shibuya; Kai Shibata; Satoko Tahara-Hanaoka; Akira Shibuya

J Immunol (2006) 176 (7): 3855.

View articletitled, Comment on “CD226 Is Specifically Expressed on the Surface of Th1 Cells and Regulates Their Expansion and Effector Functions”

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Response to Comment on “CD226 Is Specifically Expressed on the Surface of Th1 Cells and Regulates Their Expansion and Effector Functions”

Valerie Dardalhon; Anna S. Schubart; Vijay K. Kuchroo

J Immunol (2006) 176 (7): 3856.

View articletitled, Response to Comment on “CD226 Is Specifically Expressed on the Surface of Th1 Cells and Regulates Their Expansion and Effector Functions”

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Comment on “Cutting Edge: TLR4 Deficiency Confers Susceptibility to Lethal Oxidant Lung Injury”

Hiroshi Kubo; Kota Ishizawa

J Immunol (2006) 176 (7): 3856–3857.

View articletitled, Comment on “Cutting Edge: TLR4 Deficiency Confers Susceptibility to Lethal Oxidant Lung Injury”

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Response to Comment on “Cutting Edge: TLR4 Deficiency Confers Susceptibility to Lethal Oxidant Lung Injury”

Xuchen Zhang; Patty J. Lee

J Immunol (2006) 176 (7): 3857.

View articletitled, Response to Comment on “Cutting Edge: TLR4 Deficiency Confers Susceptibility to Lethal Oxidant Lung Injury”

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PILLARS OF IMMUNOLOGY

The Birth of Functionally Distinct T Cell Subsets

Leonard Chess

J Immunol (2006) 176 (7): 3859–3860.

View articletitled, The Birth of Functionally Distinct T Cell Subsets

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Pillars Article: Functional Subclasses of T Lymphocytes Bearing Different Ly Antigens. I. The Generation of Functionally Distinct T-Cell Subclasses is a Differentiative Process Independent of Antigen. J. Exp. Med. 1975. 141: 1376–1389.

H. Cantor; E. A. Boyse

J Immunol (2006) 176 (7): 3861–3874.

View articletitled, Pillars Article: Functional Subclasses of T Lymphocytes Bearing Different Ly Antigens. I. The Generation of Functionally Distinct T-Cell Subclasses is a Differentiative Process Independent of Antigen. J. Exp. Med. 1975. 141: 1376–1389.

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BRIEF REVIEWS

The P2X₇ Receptor: A Key Player in IL-1 Processing and Release ¹

Davide Ferrari; Cinzia Pizzirani; Elena Adinolfi; Roberto M. Lemoli; Antonio Curti; Marco Idzko; Elisabeth Panther; Francesco Di Virgilio

J Immunol (2006) 176 (7): 3877–3883.

Abstract

View articletitled, The P2X7 Receptor: A Key Player in IL-1 Processing and Release<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CUTTING EDGE

Cutting Edge: Diminished T Cell TLR Expression and Function Modulates the Immune Response in Human Filarial Infection ¹

Subash Babu; Carla P. Blauvelt; V. Kumaraswami; Thomas B. Nutman

J Immunol (2006) 176 (7): 3885–3889.

Abstract

View articletitled, Cutting Edge: Diminished T Cell TLR Expression and Function Modulates the Immune Response in Human Filarial Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Enhanced Pulmonary Clearance of Pseudomonas aeruginosa by Muc1 Knockout Mice ¹

Wenju Lu; Akinori Hisatsune; Takeshi Koga; Kosuke Kato; Ippei Kuwahara; Erik P. Lillehoj; Wilbur Chen; Alan S. Cross; Sandra J. Gendler; Andrew T. Gewirtz; K. Chul Kim

J Immunol (2006) 176 (7): 3890–3894.

Abstract

View articletitled, Cutting Edge: Enhanced Pulmonary Clearance of Pseudomonas aeruginosa by Muc1 Knockout Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Itk-Dependent Signals Required for CD4⁺ T Cells to Exert, but Not Gain, Th2 Effector Function ¹

Byron B. Au-Yeung; Shoshana D. Katzman; Deborah J. Fowell

J Immunol (2006) 176 (7): 3895–3899.

Abstract

View articletitled, Cutting Edge: Itk-Dependent Signals Required for CD4+ T Cells to Exert, but Not Gain, Th2 Effector Function<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: IL-4-Induced Protection of CD4⁺CD25⁻ Th Cells from CD4⁺CD25⁺ Regulatory T Cell-Mediated Suppression ¹

Luigia Pace; Stefania Rizzo; Cecilia Palombi; Frank Brombacher; Gino Doria

J Immunol (2006) 176 (7): 3900–3904.

Abstract

View articletitled, Cutting Edge: IL-4-Induced Protection of CD4+CD25− Th Cells from CD4+CD25+ Regulatory T Cell-Mediated Suppression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cutting Edge: Elimination of an Endogenous Adjuvant Reduces the Activation of CD8 T Lymphocytes to Transplanted Cells and in an Autoimmune Diabetes Model

Yan Shi; Shelly A. Galusha; Kenneth L. Rock

J Immunol (2006) 176 (7): 3905–3908.

Abstract

View articletitled, Cutting Edge: Elimination of an Endogenous Adjuvant Reduces the Activation of CD8 T Lymphocytes to Transplanted Cells and in an Autoimmune Diabetes Model

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Cutting Edge: B and T Lymphocyte Attenuator and Programmed Death Receptor-1 Inhibitory Receptors Are Required for Termination of Acute Allergic Airway Inflammation ¹

Christine Deppong; Twyla I. Juehne; Michelle Hurchla; Lindzy D. Friend; Dulari D. Shah; Christine M. Rose; Traci L. Bricker; Laurie P. Shornick; Erika C. Crouch; Theresa L. Murphy; Michael J. Holtzman; Kenneth M. Murphy; Jonathan M. Green

J Immunol (2006) 176 (7): 3909–3913.

Abstract

View articletitled, Cutting Edge: B and T Lymphocyte Attenuator and Programmed Death Receptor-1 Inhibitory Receptors Are Required for Termination of Acute Allergic Airway Inflammation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Dominant Tolerance to Kidney Allografts Induced by Anti-Donor MHC Class II Antibodies: Cooperation between T and Non-T CD103⁺ Cells

Nicolas Degauque; David Lair; Alexandre Dupont; Anne Moreau; Gwénaelle Roussey; Frédérique Moizant; François Xavier Hubert; Cédric Louvet; Marcelo Hill; Fabienne Haspot; Régis Josien; Claire Usal; Bernard Vanhove; Jean Paul Soulillou; Sophie Brouard

J Immunol (2006) 176 (7): 3915–3922.

Abstract

View articletitled, Dominant Tolerance to Kidney Allografts Induced by Anti-Donor MHC Class II Antibodies: Cooperation between T and Non-T CD103+ Cells

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Nitric Oxide Promotes Resistance to Tumor Suppression by CTLs ¹

Zhanhai Su; Jürgen Kuball; Ana-Paula Barreiros; Daniela Gottfried; Edite Antunes Ferreira; Matthias Theobald; Peter R. Galle; Dennis Strand; Susanne Strand

J Immunol (2006) 176 (7): 3923–3930.

Abstract

View articletitled, Nitric Oxide Promotes Resistance to Tumor Suppression by CTLs<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HIV-1 Envelope Triggers Polyclonal Ig Class Switch Recombination through a CD40-Independent Mechanism Involving BAFF and C-Type Lectin Receptors ¹

Bing He; Xugang Qiao; Per J. Klasse; April Chiu; Amy Chadburn; Daniel M. Knowles; John P. Moore; Andrea Cerutti

J Immunol (2006) 176 (7): 3931–3941.

Abstract

View articletitled, HIV-1 Envelope Triggers Polyclonal Ig Class Switch Recombination through a CD40-Independent Mechanism Involving BAFF and C-Type Lectin Receptors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phenotypic and Functional Similarity of Gut Intraepithelial and Systemic T Cells in a Teleost Fish ¹

David Bernard; Adrien Six; Lionel Rigottier-Gois; Sébastien Messiaen; Stefan Chilmonczyk; Edwige Quillet; Pierre Boudinot; Abdenour Benmansour

J Immunol (2006) 176 (7): 3942–3949.

Abstract

View articletitled, Phenotypic and Functional Similarity of Gut Intraepithelial and Systemic T Cells in a Teleost Fish<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Desiccating Stress Induces T Cell-Mediated Sjögren’s Syndrome-Like Lacrimal Keratoconjunctivitis ¹

Jerry Y. Niederkorn; Michael E. Stern; Stephen C. Pflugfelder; Cintia S. De Paiva; Rosa M. Corrales; Jianping Gao; Karyn Siemasko

J Immunol (2006) 176 (7): 3950–3957.

Abstract

View articletitled, Desiccating Stress Induces T Cell-Mediated Sjögren’s Syndrome-Like Lacrimal Keratoconjunctivitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Downstream of Tyrosine Kinases-1 and Src Homology 2-Containing Inositol 5′-Phosphatase Are Required for Regulation of CD4⁺CD25⁺ T Cell Development ¹

Masaki Kashiwada; Giorgio Cattoretti; Lisa McKeag; Todd Rouse; Brian M. Showalter; Umaima Al-Alem; Masaru Niki; Pier Paolo Pandolfi; Elizabeth H. Field; Paul B. Rothman

J Immunol (2006) 176 (7): 3958–3965.

Abstract

View articletitled, Downstream of Tyrosine Kinases-1 and Src Homology 2-Containing Inositol 5′-Phosphatase Are Required for Regulation of CD4+CD25+ T Cell Development<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Apoptotic Death Concurrent with CD3 Stimulation in Primary Human CD8⁺ T Lymphocytes: A Role for Endogenous Granzyme B ¹

Mireille Laforge; Nicolas Bidère; Sylvie Carmona; Aurore Devocelle; Bernard Charpentier; Anna Senik

J Immunol (2006) 176 (7): 3966–3977.

Abstract

View articletitled, Apoptotic Death Concurrent with CD3 Stimulation in Primary Human CD8+ T Lymphocytes: A Role for Endogenous Granzyme B<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL-7 Is a Critical Factor in Modulating Lesion Development in Skn-Directed Autoimmunity ¹

Pamela J. Staton; A. Betts Carpenter; Susan H. Jackman

J Immunol (2006) 176 (7): 3978–3986.

Abstract

View articletitled, IL-7 Is a Critical Factor in Modulating Lesion Development in Skn-Directed Autoimmunity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Protein Kinase Bα Is Required for Vesicle Trafficking and Class II Presentation of IgA Fc Receptor (CD89)-Targeted Antigen ¹

Gillian A. Lang; Mark L. Lang

J Immunol (2006) 176 (7): 3987–3994.

Abstract

View articletitled, Protein Kinase Bα Is Required for Vesicle Trafficking and Class II Presentation of IgA Fc Receptor (CD89)-Targeted Antigen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Essential Role of IκB Kinase α in Thymic Organogenesis Required for the Establishment of Self-Tolerance ¹

Dan Kinoshita; Fumiko Hirota; Tsuneyasu Kaisho; Michiyuki Kasai; Keisuke Izumi; Yoshimi Bando; Yasuhiro Mouri; Akemi Matsushima; Shino Niki; Hongwei Han; Kiyotaka Oshikawa; Noriyuki Kuroda; Masahiko Maegawa; Minoru Irahara; Kiyoshi Takeda; Shizuo Akira; Mitsuru Matsumoto

J Immunol (2006) 176 (7): 3995–4002.

Abstract

View articletitled, Essential Role of IκB Kinase α in Thymic Organogenesis Required for the Establishment of Self-Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Distinct, Cross-Reactive Epitope Specificities of CD8 T Cell Responses Are Induced by Natural Hepatitis B Surface Antigen Variants of Different Hepatitis B Virus Genotypes ¹

Petra Riedl; Antonio Bertoletti; Ross Lopes; Francois Lemonnier; Jörg Reimann; Reinhold Schirmbeck

J Immunol (2006) 176 (7): 4003–4011.

Abstract

View articletitled, Distinct, Cross-Reactive Epitope Specificities of CD8 T Cell Responses Are Induced by Natural Hepatitis B Surface Antigen Variants of Different Hepatitis B Virus Genotypes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Peripheral T Cell Tolerance by Antigen-Presenting B Cells. I. Relevance of Antigen Presentation Persistence ¹

Giorgio Raimondi; Ivan Zanoni; Stefania Citterio; Paola Ricciardi-Castagnoli; Francesca Granucci

J Immunol (2006) 176 (7): 4012–4020.

Abstract

View articletitled, Induction of Peripheral T Cell Tolerance by Antigen-Presenting B Cells. I. Relevance of Antigen Presentation Persistence<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Induction of Peripheral T Cell Tolerance by Antigen-Presenting B Cells. II. Chronic Antigen Presentation Overrules Antigen-Presenting B Cell Activation ¹

Giorgio Raimondi; Ivan Zanoni; Stefania Citterio; Paola Ricciardi-Castagnoli; Francesca Granucci

J Immunol (2006) 176 (7): 4021–4028.

Abstract

View articletitled, Induction of Peripheral T Cell Tolerance by Antigen-Presenting B Cells. II. Chronic Antigen Presentation Overrules Antigen-Presenting B Cell Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Suppressor of Cytokine Signaling 1 Stringently Regulates Distinct Functions of IL-7 and IL-15 In Vivo during T Lymphocyte Development and Homeostasis ¹

Sheela Ramanathan; Julien Gagnon; Chantal Leblanc; Robert Rottapel; Subburaj Ilangumaran

J Immunol (2006) 176 (7): 4029–4041.

Abstract

View articletitled, Suppressor of Cytokine Signaling 1 Stringently Regulates Distinct Functions of IL-7 and IL-15 In Vivo during T Lymphocyte Development and Homeostasis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunization-Induced Perturbation of Human Blood Plasma Cell Pool: Progressive Maturation, IL-6 Responsiveness, and High PRDI-BF1/BLIMP1 Expression Are Critical Distinctions between Antigen-Specific and Nonspecific Plasma Cells ¹

Inés González-García; Esther Ocaña; Gema Jiménez-Gómez; Antonio Campos-Caro; José A. Brieva

J Immunol (2006) 176 (7): 4042–4050.

Abstract

View articletitled, Immunization-Induced Perturbation of Human Blood Plasma Cell Pool: Progressive Maturation, IL-6 Responsiveness, and High PRDI-BF1/BLIMP1 Expression Are Critical Distinctions between Antigen-Specific and Nonspecific Plasma Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Effector T Cell Differentiation and Memory T Cell Maintenance Outside Secondary Lymphoid Organs ¹

Jagdeep S. Obhrai; Martin H. Oberbarnscheidt; Timothy W. Hand; Lonnette Diggs; Geetha Chalasani; Fadi G. Lakkis

J Immunol (2006) 176 (7): 4051–4058.

Abstract

View articletitled, Effector T Cell Differentiation and Memory T Cell Maintenance Outside Secondary Lymphoid Organs<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Long-Term Retention of Mature NK1.1⁺ NKT Cells in the Thymus ¹

Stuart P. Berzins; Finlay W. McNab; Claerwen M. Jones; Mark J. Smyth; Dale I. Godfrey

J Immunol (2006) 176 (7): 4059–4065.

Abstract

View articletitled, Long-Term Retention of Mature NK1.1+ NKT Cells in the Thymus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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EphA Receptors Inhibit Anti-CD3-Induced Apoptosis in Thymocytes ¹

Andrew Freywald; Nigel Sharfe; Charlotte D’E. Miller; Cher Rashotte; Chaim M. Roifman

J Immunol (2006) 176 (7): 4066–4074.

Abstract

View articletitled, EphA Receptors Inhibit Anti-CD3-Induced Apoptosis in Thymocytes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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T Cells Lacking Immunoproteasome Subunits MECL-1 and LMP7 Hyperproliferate in Response to Polyclonal Mitogens ¹

Christy M. Caudill; Krupakar Jayarapu; Laura Elenich; John J. Monaco; Robert A. Colbert; Thomas A. Griffin

J Immunol (2006) 176 (7): 4075–4082.

Abstract

View articletitled, T Cells Lacking Immunoproteasome Subunits MECL-1 and LMP7 Hyperproliferate in Response to Polyclonal Mitogens<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Rapid Demethylation of the IFN-γ Gene Occurs in Memory but Not Naive CD8 T Cells ¹

Ellen N. Kersh; David R. Fitzpatrick; Kaja Murali-Krishna; John Shires; Samuel H. Speck; Jeremy M. Boss; Rafi Ahmed

J Immunol (2006) 176 (7): 4083–4093.

Abstract

View articletitled, Rapid Demethylation of the IFN-γ Gene Occurs in Memory but Not Naive CD8 T Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses ¹

J Immunol (2006) 176 (7): 4094–4101.

Abstract

View articletitled, Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Supplementary data

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Mast Cell-Associated TNF Promotes Dendritic Cell Migration ¹

Hajime Suto; Susumu Nakae; Maki Kakurai; Jonathon D. Sedgwick; Mindy Tsai; Stephen J. Galli

J Immunol (2006) 176 (7): 4102–4112.

Abstract

View articletitled, Mast Cell-Associated TNF Promotes Dendritic Cell Migration<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immature NK Cells Suppress Dendritic Cell Functions during the Development of Leukemia in a Mouse Model

Kazumi Ebata; Yukihiro Shimizu; Yasuhiro Nakayama; Masami Minemura; Jun Murakami; Tsutomu Kato; Satoshi Yasumura; Terumi Takahara; Toshiro Sugiyama; Shigeru Saito

J Immunol (2006) 176 (7): 4113–4124.

Abstract

View articletitled, Immature NK Cells Suppress Dendritic Cell Functions during the Development of Leukemia in a Mouse Model

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CD4⁺ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody ¹

Keisuke Minamimura; Wenda Gao; Takashi Maki

J Immunol (2006) 176 (7): 4125–4132.

Abstract

View articletitled, CD4+ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Novel Inhibitory NKR-P1C Receptor and Ly49s3 Identify Two Complementary, Functionally Distinct NK Cell Subsets in Rats ¹

Lise Kveberg; Camilla J. Bäck; Ke-Zheng Dai; Marit Inngjerdingen; Bent Rolstad; James C. Ryan; John T. Vaage; Christian Naper

J Immunol (2006) 176 (7): 4133–4140.

Abstract

View articletitled, The Novel Inhibitory NKR-P1C Receptor and Ly49s3 Identify Two Complementary, Functionally Distinct NK Cell Subsets in Rats<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mast Cell-Dependent Down-Regulation of Antigen-Specific Immune Responses by Mosquito Bites ¹

Nadya Depinay; Fériel Hacini; Walid Beghdadi; Roger Peronet; Salaheddine Mécheri

J Immunol (2006) 176 (7): 4141–4146.

Abstract

View articletitled, Mast Cell-Dependent Down-Regulation of Antigen-Specific Immune Responses by Mosquito Bites<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TLR3-Involved Modulation of Pregnancy Tolerance in Double-Stranded RNA-Stimulated NOD/SCID Mice ¹

Yi Lin; Zhenhong Liang; Yijing Chen; Yaoying Zeng

J Immunol (2006) 176 (7): 4147–4154.

Abstract

View articletitled, TLR3-Involved Modulation of Pregnancy Tolerance in Double-Stranded RNA-Stimulated NOD/SCID Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Relationships between Distinct Blood Monocyte Subsets and Migrating Intestinal Lymph Dendritic Cells In Vivo under Steady-State Conditions

Ulf Yrlid; Christopher D. Jenkins; G. Gordon MacPherson

J Immunol (2006) 176 (7): 4155–4162.

Abstract

View articletitled, Relationships between Distinct Blood Monocyte Subsets and Migrating Intestinal Lymph Dendritic Cells In Vivo under Steady-State Conditions

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Expression of the Adaptor Protein Hematopoietic Src Homology 2 is Up-Regulated in Response to Stimuli That Promote Survival and Differentiation of B Cells

Brantley R. Herrin; Louis B. Justement

J Immunol (2006) 176 (7): 4163–4172.

Abstract

View articletitled, Expression of the Adaptor Protein Hematopoietic Src Homology 2 is Up-Regulated in Response to Stimuli That Promote Survival and Differentiation of B Cells

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

A Novel NF-κB Binding Site Controls Human Granzyme B Gene Transcription ¹

Chunjian Huang; Enguang Bi; Yu Hu; Weiwen Deng; Zhigang Tian; Chen Dong; Yuanjie Hu; Bing Sun

J Immunol (2006) 176 (7): 4173–4181.

Abstract

View articletitled, A Novel NF-κB Binding Site Controls Human Granzyme B Gene Transcription<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Transactivator of Transcription from HIV Type 1 Subtype E Selectively Inhibits TNF Gene Expression via Interference with Chromatin Remodeling of the TNF Locus ¹

Shahin Ranjbar; Ricardo Rajsbaum; Anne E. Goldfeld

J Immunol (2006) 176 (7): 4182–4190.

Abstract

View articletitled, Transactivator of Transcription from HIV Type 1 Subtype E Selectively Inhibits TNF Gene Expression via Interference with Chromatin Remodeling of the TNF Locus<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Costimulatory Receptors in a Teleost Fish: Typical CD28, Elusive CTLA4 ¹

David Bernard; Béatrice Riteau; John D. Hansen; Ruth B. Phillips; Frédérique Michel; Pierre Boudinot; Abdenour Benmansour

J Immunol (2006) 176 (7): 4191–4200.

Abstract

View articletitled, Costimulatory Receptors in a Teleost Fish: Typical CD28, Elusive CTLA4<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of Fyn in the Rearrangement of Tubulin Cytoskeleton Induced through TCR ¹

Noa B. Martín-Cófreces; David Sancho; Edgar Fernández; Miguel Vicente-Manzanares; Mónica Gordón-Alonso; María C. Montoya; Frédérique Michel; Oreste Acuto; Balbino Alarcón; Francisco Sánchez-Madrid

J Immunol (2006) 176 (7): 4201–4207.

Abstract

View articletitled, Role of Fyn in the Rearrangement of Tubulin Cytoskeleton Induced through TCR<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Small Molecules That Enhance the Catalytic Efficiency of HLA-DM ¹

Melissa J. Nicholson; Babak Moradi; Nilufer P. Seth; Xuechao Xing; Gregory D. Cuny; Ross L. Stein; Kai W. Wucherpfennig

J Immunol (2006) 176 (7): 4208–4220.

Abstract

View articletitled, Small Molecules That Enhance the Catalytic Efficiency of HLA-DM<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IMMUNOGENETICS

Complete Sequence Assembly and Characterization of the C57BL/6 Mouse Ig Heavy Chain V Region ¹

Colette M. Johnston; Andrew L. Wood; Daniel J. Bolland; Anne E. Corcoran

J Immunol (2006) 176 (7): 4221–4234.

Abstract

View articletitled, Complete Sequence Assembly and Characterization of the C57BL/6 Mouse Ig Heavy Chain V Region<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HOST DEFENSE

CXCL10 Is the Key Ligand for CXCR3 on CD8⁺ Effector T Cells Involved in Immune Surveillance of the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System ¹

Jeanette Erbo Christensen; Carina de Lemos; Torben Moos; Jan Pravsgaard Christensen; Allan Randrup Thomsen

J Immunol (2006) 176 (7): 4235–4243.

Abstract

View articletitled, CXCL10 Is the Key Ligand for CXCR3 on CD8+ Effector T Cells Involved in Immune Surveillance of the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α ¹

Sachiko Akashi-Takamura; Takahisa Furuta; Koichiro Takahashi; Natsuko Tanimura; Yutaka Kusumoto; Toshihiko Kobayashi; Shin-ichiroh Saitoh; Yoshiyuki Adachi; Takahiro Doi; Kensuke Miyake

J Immunol (2006) 176 (7): 4244–4251.

Abstract

View articletitled, Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Hemin Activation Ameliorates HIV-1 Infection via Heme Oxygenase-1 Induction

Krishnakumar Devadas; Subhash Dhawan

J Immunol (2006) 176 (7): 4252–4257.

Abstract

View articletitled, Hemin Activation Ameliorates HIV-1 Infection via Heme Oxygenase-1 Induction

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Trypsin-Sensitive Modulation of Intestinal Epithelial MD-2 as Mechanism of Lipopolysaccharide Tolerance ¹

Elke Cario; Douglas T. Golenbock; Alberto Visintin; Michael Rünzi; Guido Gerken; Daniel K. Podolsky

J Immunol (2006) 176 (7): 4258–4266.

Abstract

View articletitled, Trypsin-Sensitive Modulation of Intestinal Epithelial MD-2 as Mechanism of Lipopolysaccharide Tolerance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Macrophage Apoptosis in Response to High Intracellular Burden of Mycobacterium tuberculosis Is Mediated by a Novel Caspase-Independent Pathway ¹

Jinhee Lee; Heinz G. Remold; Michael H. Ieong; Hardy Kornfeld

J Immunol (2006) 176 (7): 4267–4274.

Abstract

View articletitled, Macrophage Apoptosis in Response to High Intracellular Burden of Mycobacterium tuberculosis Is Mediated by a Novel Caspase-Independent Pathway<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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TLRs Regulate the Gatekeeping Functions of the Intestinal Follicle-Associated Epithelium ¹

Sophie Chabot; Jessica S. Wagner; Stephanie Farrant; Marian R. Neutra

J Immunol (2006) 176 (7): 4275–4283.

Abstract

View articletitled, TLRs Regulate the Gatekeeping Functions of the Intestinal Follicle-Associated Epithelium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IFN-Induced Attrition of CD8 T Cells in the Presence or Absence of Cognate Antigen during the Early Stages of Viral Infections ¹

Kapil Bahl; Sung-Kwon Kim; Claudia Calcagno; Dario Ghersi; Roberto Puzone; Franco Celada; Liisa K. Selin; Raymond M. Welsh

J Immunol (2006) 176 (7): 4284–4295.

Abstract

View articletitled, IFN-Induced Attrition of CD8 T Cells in the Presence or Absence of Cognate Antigen during the Early Stages of Viral Infections<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Contribution of CD8⁺ T Cells to Control of Mycobacterium tuberculosis Infection ¹

Dhruv Sud; Carolyn Bigbee; JoAnne L. Flynn; Denise E. Kirschner

J Immunol (2006) 176 (7): 4296–4314.

Abstract

View articletitled, Contribution of CD8+ T Cells to Control of Mycobacterium tuberculosis Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Complement Component C3 Is Required for Protective Innate and Adaptive Immunity to Larval Strongyloides stercoralis in Mice ¹

Laura A. Kerepesi; Jessica A. Hess; Thomas J. Nolan; Gerhard A. Schad; David Abraham

J Immunol (2006) 176 (7): 4315–4322.

Abstract

View articletitled, Complement Component C3 Is Required for Protective Innate and Adaptive Immunity to Larval Strongyloides stercoralis in Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mycobacterium tuberculosis 19-kDa Lipoprotein Inhibits IFN-γ-Induced Chromatin Remodeling of MHC2TA by TLR2 and MAPK Signaling ¹

Meghan E. Pennini; Rish K. Pai; David C. Schultz; W. Henry Boom; Clifford V. Harding

J Immunol (2006) 176 (7): 4323–4330.

Abstract

View articletitled, Mycobacterium tuberculosis 19-kDa Lipoprotein Inhibits IFN-γ-Induced Chromatin Remodeling of MHC2TA by TLR2 and MAPK Signaling<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Homing and Function of Human Skin γδ T Cells and NK Cells: Relevance for Tumor Surveillance

Lisa M. Ebert; Simone Meuter; Bernhard Moser

J Immunol (2006) 176 (7): 4331–4336.

Abstract

View articletitled, Homing and Function of Human Skin γδ T Cells and NK Cells: Relevance for Tumor Surveillance

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Distinct Roles of TLR2 and the Adaptor ASC in IL-1β/IL-18 Secretion in Response to Listeria monocytogenes¹

Nesrin Özören; Junya Masumoto; Luigi Franchi; Thirumala-Devi Kanneganti; Mathilde Body-Malapel; İlkim Ertürk; Rajesh Jagirdar; Li Zhu; Naohiro Inohara; John Bertin; Anthony Coyle; Ethan P. Grant; Gabriel Núñez

J Immunol (2006) 176 (7): 4337–4342.

Abstract

View articletitled, Distinct Roles of TLR2 and the Adaptor ASC in IL-1β/IL-18 Secretion in Response to Listeria monocytogenes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Type I IFN Receptor Signals Directly Stimulate Local B Cells Early following Influenza Virus Infection ¹

Elizabeth S. Coro; W. L. William Chang; Nicole Baumgarth

J Immunol (2006) 176 (7): 4343–4351.

Abstract

View articletitled, Type I IFN Receptor Signals Directly Stimulate Local B Cells Early following Influenza Virus Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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INFLAMMATION

Oncostatin-M Up-Regulates VCAM-1 and Synergizes with IL-4 in Eotaxin Expression: Involvement of STAT6 ¹

Dominik K. Fritz; Christine Kerr; Li Tong; David Smyth; Carl D. Richards

J Immunol (2006) 176 (7): 4352–4360.

Abstract

View articletitled, Oncostatin-M Up-Regulates VCAM-1 and Synergizes with IL-4 in Eotaxin Expression: Involvement of STAT6<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Lung-Restricted Macrophage Activation in the Pearl Mouse Model of Hermansky-Pudlak Syndrome ¹

Lisa R. Young; Michael T. Borchers; Holly L. Allen; Reta S. Gibbons; Francis X. McCormack

J Immunol (2006) 176 (7): 4361–4368.

Abstract

View articletitled, Lung-Restricted Macrophage Activation in the Pearl Mouse Model of Hermansky-Pudlak Syndrome<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Role of the Property of C-Reactive Protein to Activate the Classical Pathway of Complement in Protecting Mice from Pneumococcal Infection ¹

Madathilparambil V. Suresh; Sanjay K. Singh; Donald A. Ferguson, Jr.; Alok Agrawal

J Immunol (2006) 176 (7): 4369–4374.

Abstract

View articletitled, Role of the Property of C-Reactive Protein to Activate the Classical Pathway of Complement in Protecting Mice from Pneumococcal Infection<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Critical Role for Mast Cells in the Pathogenesis of 2,4-Dinitrobenzene-Induced Murine Colonic Hypersensitivity Reaction

Anneke Rijnierse; Andries S. Koster; Frans P. Nijkamp; Aletta D. Kraneveld

J Immunol (2006) 176 (7): 4375–4384.

Abstract

View articletitled, Critical Role for Mast Cells in the Pathogenesis of 2,4-Dinitrobenzene-Induced Murine Colonic Hypersensitivity Reaction

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IL-4-Induced Peroxisome Proliferator-Activated Receptor γ Activation Inhibits NF-κB Trans Activation in Central Nervous System (CNS) Glial Cells and Protects Oligodendrocyte Progenitors under Neuroinflammatory Disease Conditions: Implication for CNS-Demyelinating Diseases ¹

Ajaib S. Paintlia; Manjeet K. Paintlia; Inderjit Singh; Avtar K. Singh

J Immunol (2006) 176 (7): 4385–4398.

Abstract

View articletitled, IL-4-Induced Peroxisome Proliferator-Activated Receptor γ Activation Inhibits NF-κB Trans Activation in Central Nervous System (CNS) Glial Cells and Protects Oligodendrocyte Progenitors under Neuroinflammatory Disease Conditions: Implication for CNS-Demyelinating Diseases<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Severe Disease, Unaltered Leukocyte Migration, and Reduced IFN-γ Production in CXCR3^−/− Mice with Experimental Autoimmune Encephalomyelitis ¹

LiPing Liu; DeRen Huang; Masaru Matsui; Toby T. He; Taofang Hu; Julie DeMartino; Bao Lu; Craig Gerard; Richard M. Ransohoff

J Immunol (2006) 176 (7): 4399–4409.

Abstract

View articletitled, Severe Disease, Unaltered Leukocyte Migration, and Reduced IFN-γ Production in CXCR3−/− Mice with Experimental Autoimmune Encephalomyelitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Spatial and Temporal Profiles for Anti-Inflammatory Gene Expression in Leukocytes during a Resolving Model of Peritonitis ¹

Amilcar S. Damazo; Simon Yona; Roderick J. Flower; Mauro Perretti; Sonia M. Oliani

J Immunol (2006) 176 (7): 4410–4418.

Abstract

View articletitled, Spatial and Temporal Profiles for Anti-Inflammatory Gene Expression in Leukocytes during a Resolving Model of Peritonitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CSMD1 Is a Novel Multiple Domain Complement-Regulatory Protein Highly Expressed in the Central Nervous System and Epithelial Tissues ¹

Damian M. Kraus; Gary S. Elliott; Hilary Chute; Thomas Horan; Karl H. Pfenninger; Staci D. Sanford; Stephen Foster; Sheila Scully; Andrew A. Welcher; V. Michael Holers

J Immunol (2006) 176 (7): 4419–4430.

Abstract

View articletitled, CSMD1 Is a Novel Multiple Domain Complement-Regulatory Protein Highly Expressed in the Central Nervous System and Epithelial Tissues<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Vast Majority of CLA⁺ T Cells Are Resident in Normal Skin ¹

Rachael A. Clark; Benjamin Chong; Nina Mirchandani; Nooshin K. Brinster; Kei-ichi Yamanaka; Rebecca K. Dowgiert; Thomas S. Kupper

J Immunol (2006) 176 (7): 4431–4439.

Abstract

View articletitled, The Vast Majority of CLA+ T Cells Are Resident in Normal Skin<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cysteinyl Leukotrienes Regulate Th2 Cell-Dependent Pulmonary Inflammation ¹

Daniel C. Kim; F. Ida Hsu; Nora A. Barrett; Daniel S. Friend; Roland Grenningloh; I-Cheng Ho; Amal Al-Garawi; Jose M. Lora; Bing K. Lam; K. Frank Austen; Yoshihide Kanaoka

J Immunol (2006) 176 (7): 4440–4448.

Abstract

View articletitled, Cysteinyl Leukotrienes Regulate Th2 Cell-Dependent Pulmonary Inflammation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Ecto-5′-Nucleotidase (CD73)-Mediated Adenosine Production Is Tissue Protective in a Model of Bleomycin-Induced Lung Injury ¹

Jonathan B. Volmer; Linda F. Thompson; Michael R. Blackburn

J Immunol (2006) 176 (7): 4449–4458.

Abstract

View articletitled, Ecto-5′-Nucleotidase (CD73)-Mediated Adenosine Production Is Tissue Protective in a Model of Bleomycin-Induced Lung Injury<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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CLINICAL IMMUNOLOGY

Monitoring the Antitumor Response of Naive and Memory CD8 T Cells in RAG1^−/− Mice by Positron-Emission Tomography ¹

Helen Su; Daisy S. Chang; Sanjiv S. Gambhir; Jonathan Braun

J Immunol (2006) 176 (7): 4459–4467.

Abstract

View articletitled, Monitoring the Antitumor Response of Naive and Memory CD8 T Cells in RAG1−/− Mice by Positron-Emission Tomography<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Potential of Adiponectin in Driving Arthritis ¹

Angela Ehling; Andreas Schäffler; Hans Herfarth; Ingo H. Tarner; Sven Anders; Oliver Distler; Gisela Paul; Jörg Distler; Steffen Gay; Jürgen Schölmerich; Elena Neumann; Ulf Müller-Ladner

J Immunol (2006) 176 (7): 4468–4478.

Abstract

View articletitled, The Potential of Adiponectin in Driving Arthritis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Iodination of Tyrosyls in Thyroglobulin Generates Neoantigenic Determinants That Cause Thyroiditis ¹

Haiyan S. Li; George Carayanniotis

J Immunol (2006) 176 (7): 4479–4483.

Abstract

View articletitled, Iodination of Tyrosyls in Thyroglobulin Generates Neoantigenic Determinants That Cause Thyroiditis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Functional Study of CD4⁺CD25⁺ Regulatory T Cells in Health and Autoimmune Hepatitis ¹

Maria Serena Longhi; Munther J. Hussain; Ragai R. Mitry; Sunil K. Arora; Giorgina Mieli-Vergani; Diego Vergani; Yun Ma

J Immunol (2006) 176 (7): 4484–4491.

Abstract

View articletitled, Functional Study of CD4+CD25+ Regulatory T Cells in Health and Autoimmune Hepatitis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Issues

IN THIS ISSUE

LETTERS TO THE EDITOR

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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