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Issues
15 December 2006
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
BRIEF REVIEWS
Alternative Translational Products and Cryptic T Cell Epitopes: Expecting the Unexpected
J Immunol (2006) 177 (12): 8283–8289.
CUTTING EDGE
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Functional Adaptive CD4 Foxp3 T Cells Develop in MHC Class II-Deficient Mice1
J Immunol (2006) 177 (12): 8307–8314.
Human Mast Cell Chymase Cleaves Pro-IL-18 and Generates a Novel and Biologically Active IL-18 Fragment1
Youichi Omoto; Kazuya Tokime; Keiichi Yamanaka; Koji Habe; Tatsuhiko Morioka; Ichiro Kurokawa; Hiroko Tsutsui; Kiyofumi Yamanishi; Kenji Nakanishi; Hitoshi Mizutani
J Immunol (2006) 177 (12): 8315–8319.
Latent Virus Influences the Generation and Maintenance of CD8+ T Cell Memory1
J Immunol (2006) 177 (12): 8356–8364.
Lunatic Fringe Controls T Cell Differentiation through Modulating Notch Signaling1
J Immunol (2006) 177 (12): 8365–8371.
Regulatory Roles of NKT Cells in the Induction and Maintenance of Cyclophosphamide-Induced Tolerance1
Toshiro Iwai; Yukihiro Tomita; Shinji Okano; Ichiro Shimizu; Yohichi Yasunami; Takashi Kajiwara; Yasunobu Yoshikai; Masaru Taniguchi; Kikuo Nomoto; Hisataka Yasui
J Immunol (2006) 177 (12): 8400–8409.
NK and CD4 Cells Collaborate to Protect against Melanoma Tumor Formation in the Brain1
Robert M. Prins; Dan D. Vo; Haumith Khan-Farooqi; Meng-Yin Yang; Horacio Soto; James S. Economou; Linda M. Liau; Antoni Ribas
J Immunol (2006) 177 (12): 8448–8455.
Interactions between T Cells Responding to Concurrent Mycobacterial and Influenza Infections1
Dominic O. Co; Laura H. Hogan; Jozsef Karman; Erika Heninger; Shoua Vang; Krisna Wells; Yoshihiro Kawaoka; Matyas Sandor
J Immunol (2006) 177 (12): 8456–8465.
Structurally Distinct Membrane Nanotubes between Human Macrophages Support Long-Distance Vesicular Traffic or Surfing of Bacteria1
Björn Önfelt; Shlomo Nedvetzki; Richard K. P. Benninger; Marco A. Purbhoo; Stefanie Sowinski; Alistair N. Hume; Miguel C. Seabra; Mark A. A. Neil; Paul M. W. French; Daniel M. Davis
J Immunol (2006) 177 (12): 8476–8483.
Treatment of Experimental Autoimmune Prostatitis in Nonobese Diabetic Mice by the Vitamin D Receptor Agonist Elocalcitol1
Giuseppe Penna; Susana Amuchastegui; Chiara Cossetti; Francesca Aquilano; Roberto Mariani; Francesca Sanvito; Claudio Doglioni; Luciano Adorini
J Immunol (2006) 177 (12): 8504–8511.
Defective Chemokine-Directed Lymphocyte Migration and Development in the Absence of Rho Guanosine Diphosphate-Dissociation Inhibitors α and β1
Hiroyoshi Ishizaki; Atsushi Togawa; Miki Tanaka-Okamoto; Keiko Hori; Miyuki Nishimura; Akiko Hamaguchi; Toshio Imai; Yoshimi Takai; Jun Miyoshi
J Immunol (2006) 177 (12): 8512–8521.
Local and Systemic Effects of Intranodally Injected CpG-C Immunostimulatory-Oligodeoxyribonucleotides in Macaques1
Natalia Teleshova; Jessica Kenney; Gary Van Nest; Jason Marshall; Jeffrey D. Lifson; Irving Sivin; Jason Dufour; Rudolf Bohm; Agegnehu Gettie; Melissa Robbiani
J Immunol (2006) 177 (12): 8531–8541.
Semimature Stage: A Checkpoint in a Dendritic Cell Maturation Program That Allows for Functional Reversion after Signal-Regulatory Protein-α Ligation and Maturation Signals1
Deborah Braun; Laurent Galibert; Toshiharu Nakajima; Hirohisa Saito; Van Vu Quang; Manuel Rubio; Marika Sarfati
J Immunol (2006) 177 (12): 8550–8559.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
A Natural Structural Variant of the Mouse TCR β-Chain Displays Intrinsic Receptor Function and Antigen Specificity1
Anne Aublin; Maria Ciofani; Nancy Willkomm; Abdelbasset Hamrouni; Andrea L. Szymczak-Workman; Tomio Takahashi; Yongoua Sandjeu; Philippe Guillaume; Dario A. A. Vignali; Olivier Michielin; Juan Carlos Zúñiga-Pflücker; Janet L. Maryanski
J Immunol (2006) 177 (12): 8587–8594.
Molecular Basis of TCR Selectivity, Cross-Reactivity, and Allelic Discrimination by a Bacterial Superantigen: Integrative Functional and Energetic Mapping of the SpeC-Vβ2.1 Molecular Interface1
A. K. M. Nur-ur Rahman; Christine A. Herfst; Beenu Moza; Stephanie R. Shames; Luan A. Chau; Clara Bueno; Joaquín Madrenas; Eric J. Sundberg; John K. McCormick
J Immunol (2006) 177 (12): 8595–8603.
Vav Proteins Regulate the Plasma Cell Program and Secretory Ig Production1
J Immunol (2006) 177 (12): 8620–8625.
IMMUNOGENETICS
Th2 Cell-Selective Enhancement of Human IL13 Transcription by IL13-1112C>T, a Polymorphism Associated with Allergic Inflammation1
Lisa Cameron; Robin B. Webster; Jannine M. Strempel; Patricia Kiesler; Michael Kabesch; Harikrishnan Ramachandran; Lizhi Yu; Debra A. Stern; Penelope E. Graves; I. Carla Lohman; Anne L. Wright; Marilyn Halonen; Walter T. Klimecki; Donata Vercelli
J Immunol (2006) 177 (12): 8633–8642.
Allorecognition of an HLA-A*01 Aberrant Allele by an HLA Identical Family Member Carrying the HLA-A*0101 Allele1
Ingrid Almeciga; Zhigang Charles Wang; Joaquin Zúñiga; Marcelo Fernandez-Viña; Olga Clavijo; Hugo Araujo; Viviana Romero; John Henry; Soldano Ferrone; Edmond J. Yunis
J Immunol (2006) 177 (12): 8643–8649.
HOST DEFENSE
β-Glucan Is a Fungal Determinant for Adhesion-Dependent Human Neutrophil Functions1
J Immunol (2006) 177 (12): 8667–8675.
High Mobility Group B1 Protein Suppresses the Human Plasmacytoid Dendritic Cell Response to TLR9 Agonists1
Petar J. Popovic; Richard DeMarco; Michael T. Lotze; Steven E. Winikoff; David L. Bartlett; Arthur M. Krieg; Z. Sheng Guo; Charles K. Brown; Kevin J. Tracey; Herbert J. Zeh, III
J Immunol (2006) 177 (12): 8701–8707.
INFLAMMATION
Inhibition of Macrophage Migration Inhibitory Factor or Its Receptor (CD74) Attenuates Growth and Invasion of DU-145 Prostate Cancer Cells1
J Immunol (2006) 177 (12): 8730–8739.
Deficiency of P-Selectin or P-Selectin Glycoprotein Ligand-1 Leads to Accelerated Development of Glomerulonephritis and Increased Expression of CC Chemokine Ligand 2 in Lupus-Prone Mice1
Xiaodong He; Trenton R. Schoeb; Angela Panoskaltsis-Mortari; Kurt R. Zinn; Robert A. Kesterson; Junxuan Zhang; Sharon Samuel; M. John Hicks; Michael J. Hickey; Daniel C. Bullard
J Immunol (2006) 177 (12): 8748–8756.
Lysozyme-Modified Probiotic Components Protect Rats against Polymicrobial Sepsis: Role of Macrophages and Cathelicidin-Related Innate Immunity1
Heng-Fu Bu; Xiao Wang; Ya-Qin Zhu; Roxanne Y. Williams; Wei Hsueh; Xiaotian Zheng; Ranna A. Rozenfeld; Xiu-Li Zuo; Xiao-Di Tan
J Immunol (2006) 177 (12): 8767–8776.
SHIP1 Negatively Regulates Proliferation of Osteoclast Precursors via Akt-Dependent Alterations in D-Type Cyclins and p271
J Immunol (2006) 177 (12): 8777–8784.
Gram-Negative Bacteria Aggravate Murine Small Intestinal Th1-Type Immunopathology following Oral Infection with Toxoplasma gondii1
Markus M. Heimesaat; Stefan Bereswill; André Fischer; David Fuchs; Daniela Struck; Julia Niebergall; Hannah-Katharina Jahn; Ildikò R. Dunay; Annette Moter; Dorothee M. Gescher; Ralf R. Schumann; Ulf B. Göbel; Oliver Liesenfeld
J Immunol (2006) 177 (12): 8785–8795.
CLINICAL IMMUNOLOGY
The Expression and Possible Roles of Chemokine CXCL11 and Its Receptor CXCR3 in the Human Endometrium
Yasushi Hirota; Yutaka Osuga; Kaori Koga; Osamu Yoshino; Tetsuya Hirata; Chieko Morimoto; Miyuki Harada; Yuri Takemura; Emi Nose; Tetsu Yano; Osamu Tsutsumi; Yuji Taketani
J Immunol (2006) 177 (12): 8813–8821.
Characterization of the B Cell Epitopes Associated with a Truncated Form of Pseudomonas Exotoxin (PE38) Used to Make Immunotoxins for the Treatment of Cancer Patients1
Masanori Onda; Satoshi Nagata; David J. FitzGerald; Richard Beers; Robert J. Fisher; James J. Vincent; Byungkook Lee; Michihiro Nakamura; Jaulang Hwang; Robert J. Kreitman; Raffit Hassan; Ira Pastan
J Immunol (2006) 177 (12): 8822–8834.
Familial NK Cell Deficiency Associated with Impaired IL-2- and IL-15-Dependent Survival of Lymphocytes1
Céline Eidenschenk; Emmanuelle Jouanguy; Alexandre Alcaïs; Jean-Jacques Mention; Benoit Pasquier; Ingrid M. Fleckenstein; Anne Puel; Laure Gineau; Jean-Claude Carel; Eric Vivier; Françoise Le Deist; Jean-Laurent Casanova
J Immunol (2006) 177 (12): 8835–8843.
Aberrant Regulation of Synovial T Cell Activation by Soluble Costimulatory Molecules in Rheumatoid Arthritis1
Bing Wan; Hong Nie; Ailian Liu; Guozhang Feng; Dongyi He; Rong Xu; Qi Zhang; Chen Dong; Jingwu Z. Zhang
J Immunol (2006) 177 (12): 8844–8850.
Adenovirus-Specific CD4+ T Cell Clones Recognizing Endogenous Antigen Inhibit Viral Replication In Vitro through Cognate Interaction1
Bianca Heemskerk; Tamara van Vreeswijk; Louise A. Veltrop-Duits; Claudia C. Sombroek; Kees Franken; Renate M. Verhoosel; Pieter S. Hiemstra; Daphne van Leeuwen; Maaike E. Ressing; René E. M. Toes; Maarten J. D. van Tol; Marco W. Schilham
J Immunol (2006) 177 (12): 8851–8859.
Synergism between CpG-Containing Oligodeoxynucleotides and IL-2 Causes Dramatic Enhancement of Vaccine-Elicited CD8+ T Cell Responses1
J Immunol (2006) 177 (12): 8860–8873.
CORRECTIONS
Mycobacterium tuberculosis-induced CXCR4 and chemokine expression leads to preferential X4 HIV-1 replication in human macrophages
Y. Hoshino; D. B. Tse; G. Rochford; S. Prabhakar; S. Hoshino; N. Chitkara; K. Kuwabara; E. Ching; B. Raju; J. A. Gold; W. Borkowsky; W. N. Rom; R. Pine; M. Weiden
J Immunol (2006) 177 (12): 8874.
CD8α coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10
J Immunol (2006) 177 (12): 8875–8876.
Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype
A. Leslie; D. A. Price; P. Mkhize; K. Bishop; A. Rathod; C. Day; H. Crawford; I. Honeyborne; T. E. Asher; G. Luzzi; A. Edwards; C. M. Rosseau; J. I. Mullins; G. Tudor-Williams; V. Novelli; C. Brander; D. C. Douek; P. Kiepiela; B. D. Walker; P. J. R. Goulder
J Immunol (2006) 177 (12): 8878.
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
A. Bibeau-Poirier; S.-P. Gravel; J.-F. Clément; S. Rolland; G. Rodier; P. Coulombe; J. Hiscott; N. Grandvaux; S. Meloche; M. J. Servant
J Immunol (2006) 177 (12): 8878–8879.
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Cover Image
Cover Image
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On the cover: Luminal gut bacteria (orange-yellow) were visualized in an ileal section from an uninfected C57BL/6 mouse using FISH. Cellular nuclei (blue) were stained using DAPI. Gut content contains bacteria and autofluorescent (yellow-green) food components. Following oral infection with T. gondii, overgrowth of Gram-negative bacteria is observed associated with translocation of bacteria to submucosal tissues contributing to ileal inflammation and ileal necrosis. Heimesaat, M. M., S. Bereswill, A. Fischer, D. Fuchs, D. Struck, J. Niebergall, H.-K. Jahn, I. R. Dunay, A. Moter, D. M. Gescher, R. R. Schumann, U. B. Göbel, and O. Liesenfeld. 2006. Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii. J. Immunol. 177: 8785–8795.
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